Protein: DCA16
DDB1- and CUL4-associated factor 16

Gene: DCA16, DCAF16
Organism: Homo sapiens
Interactions: 65
UniProt ID: Q9NXF7

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0016567 - protein ubiquitination
GO:0080008 - Cul4-RING E3 ubiquitin ligase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1157965

DDB1
DNA damage-binding protein 1

3

0

Small-scale

0.803

High

1115098

CUL4A
Cullin-4A

5

1

Small-scale

0.709

High

1115461

CUL4B
Cullin-4B

4

1

Small-scale

0.702

High

279519

TULP3
Tubby-related protein 3

3

0

High-throughput

0.638

High

1054800

SUH
Recombining binding protein suppressor of hairless

3

0

High-throughput

0.638

High

1433614

DEFI6
Differentially expressed in FDCP 6 homolog

3

0

High-throughput

0.638

High

1201232

SPIN4
Spindlin-4

3

0

Small-scale

0.622

High

1272575

CSN6
COP9 signalosome complex subunit 6

3

0

High-throughput

0.622

High

260538

BRD4
Bromodomain-containing protein 4

1

0

Small-scale

0.586

High

1370408

CSN5
COP9 signalosome complex subunit 5

2

0

High-throughput

0.585

High

1094426

CSN1
COP9 signalosome complex subunit 1

2

0

High-throughput

0.576

High

254442

CC14B
Dual specificity protein phosphatase CDC14B

1

1

High-throughput

0.536

High

177723

SMAD7
Mothers against decapentaplegic homolog 7

1

0

High-throughput

0.513

High

987484

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

0

High-throughput

0.513

High

1349228

PI42C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

1

0

High-throughput

0.513

High

1357769

TRI41
E3 ubiquitin-protein ligase TRIM41

1

0

High-throughput

0.513

High

1396936

ANM6
Protein arginine N-methyltransferase 6

1

1

High-throughput

0.508

High

1407914

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.508

High

961226

FGF12
Fibroblast growth factor 12

1

1

High-throughput

0.489

High

1370586

FGF11
Fibroblast growth factor 11

1

1

High-throughput

0.489

High

1451066

PKHJ1
Pleckstrin homology domain-containing family J member 1

1

1

High-throughput

0.489

High

58747

PTPC1
Protein tyrosine phosphatase domain-containing protein 1

1

1

High-throughput

0.479

High

1161883

DUS5
Dual specificity protein phosphatase 5

1

0

High-throughput

0.458

High

1357581

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.458

High

1406787

BARD1
BRCA1-associated RING domain protein 1

1

0

High-throughput

0.458

High

1415884

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

1435364

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1436508

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

1437935

SP110
Sp110 nuclear body protein

1

0

High-throughput

0.458

High

1452007

CSN7A
COP9 signalosome complex subunit 7a

1

0

High-throughput

0.458

High

722888

SSR2
Somatostatin receptor type 2

1

0

High-throughput

0.426

High

1452008

CSN3
COP9 signalosome complex subunit 3

1

0

High-throughput

0.426

High

1065034

FGL1
Fibrinogen-like protein 1

3

0

High-throughput

0.347

High

1232382

SFRP4
Secreted frizzled-related protein 4

3

0

High-throughput

0.347

High

554259

BMP4
Bone morphogenetic protein 4

2

0

High-throughput

0.328

High

1006953

KC1G2
Casein kinase I isoform gamma-2

2

0

High-throughput

0.328

High

1135535

RHG19
Rho GTPase-activating protein 19

2

0

High-throughput

0.328

High

1280024

CE024
UPF0461 protein C5orf24

2

0

High-throughput

0.328

High

1307247

TF2LY
Homeobox protein TGIF2LY

2

0

High-throughput

0.328

High

1394350

ZN414
Zinc finger protein 414

2

0

High-throughput

0.328

High

1398269

TEAN2
Transcription elongation factor A N-terminal and central domain-containing protein 2

2

0

High-throughput

0.328

High

1432719

TXNIP
Thioredoxin-interacting protein

2

0

High-throughput

0.328

High

1335955

ZBT44
Zinc finger and BTB domain-containing protein 44

2

0

High-throughput

0.318

High

1435052

CIAO3
Cytosolic iron-sulfur assembly component 3

2

0

High-throughput

0.313

High

505111

BNIP5
Protein BNIP5

1

0

High-throughput

0.279

Low

885014

DGKG
Diacylglycerol kinase gamma

1

0

High-throughput

0.279

Low

954627

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.279

Low

1052916

HME1
Homeobox protein engrailed-1

1

0

High-throughput

0.279

Low

1208246

SPXN4
Sperm protein associated with the nucleus on the X chromosome N4

1

0

High-throughput

0.279

Low

1331868

SYT2
Synaptotagmin-2

1

0

High-throughput

0.279

Low

1335352

ZN784
Zinc finger protein 784

1

0

High-throughput

0.279

Low

1371204

GLMN
Glomulin

1

0

High-throughput

0.279

Low

1398138

CC140
Coiled-coil domain-containing protein 140

1

0

High-throughput

0.279

Low

1410840

PSD2
PH and SEC7 domain-containing protein 2

1

0

High-throughput

0.279

Low

1433626

SMOC1
SPARC-related modular calcium-binding protein 1

1

0

High-throughput

0.279

Low

1435552

GREM2
Gremlin-2

1

0

High-throughput

0.279

Low

144326

ACACB
Acetyl-CoA carboxylase 2

1

0

High-throughput

0.249

Low

1249264

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

637762

FLNA
Filamin-A

1

0

High-throughput

0.249

Low

971185

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

986870

FKB1A
Peptidyl-prolyl cis-trans isomerase FKBP1A

1

0

Small-scale

0.249

Low

1211064

ARH
Low density lipoprotein receptor adapter protein 1

1

0

High-throughput

0.249

Low

1213851

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.249

Low

1327233

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low

1434057

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025