Protein: PSMD5
26S proteasome non-ATPase regulatory subunit 5 (26S protease subunit S5 basic) (26S proteasome subunit S5B)

Gene: PSMD5
Organism: Homo sapiens
Interactions: 85
UniProt ID: Q16401

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0005829 - cytosol
GO:0022624 - proteasome accessory complex
GO:0070682 - proteasome regulatory particle assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

778691

PRS7
26S proteasome regulatory subunit 7

17

5

Small-scale

0.766

High

968714

PRS4
26S proteasome regulatory subunit 4

11

5

Small-scale

0.758

High

1097997

PSMD2
26S proteasome non-ATPase regulatory subunit 2

5

2

Small-scale

0.712

High

610342

PRS6A
26S proteasome regulatory subunit 6A

5

8

Small-scale

0.709

High

1157415

PSMD1
26S proteasome non-ATPase regulatory subunit 1

4

2

Small-scale

0.687

High

138133

PSDE
26S proteasome non-ATPase regulatory subunit 14

4

1

Small-scale

0.683

High

128241

PSD12
26S proteasome non-ATPase regulatory subunit 12

3

2

Small-scale

0.662

High

851330

PRS6B
26S proteasome regulatory subunit 6B

3

5

Small-scale

0.662

High

906526

PSMD7
26S proteasome non-ATPase regulatory subunit 7

3

1

Small-scale

0.662

High

968935

PRS8
26S proteasome regulatory subunit 8

3

7

Small-scale

0.662

High

975411

PRS10
26S proteasome regulatory subunit 10B

3

5

Small-scale

0.662

High

1136524

PSMD6
26S proteasome non-ATPase regulatory subunit 6

3

2

Small-scale

0.662

High

508042

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

3

2

Small-scale

0.651

High

210959

PSMD3
26S proteasome non-ATPase regulatory subunit 3

3

0

Small-scale

0.634

High

295505

PSD10
26S proteasome non-ATPase regulatory subunit 10

3

0

High-throughput

0.634

High

874158

PSMD8
26S proteasome non-ATPase regulatory subunit 8

3

0

Small-scale

0.634

High

933649

PSMD4
26S proteasome non-ATPase regulatory subunit 4

3

0

Small-scale

0.634

High

1156444

ADRM1
Proteasomal ubiquitin receptor ADRM1

3

0

Small-scale

0.634

High

1157424

PSD13
26S proteasome non-ATPase regulatory subunit 13

3

0

Small-scale

0.634

High

127974

PSD11
26S proteasome non-ATPase regulatory subunit 11

2

3

High-throughput

0.628

High

1157426

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

3

0

Small-scale

0.622

High

1157418

BTBD2
BTB/POZ domain-containing protein 2

2

1

High-throughput

0.606

High

1157421

BTBD1
BTB/POZ domain-containing protein 1

2

1

High-throughput

0.606

High

1157408

CAST1
Cytosolic arginine sensor for mTORC1 subunit 1

2

0

High-throughput

0.580

High

929959

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

2

0

Small-scale

0.559

High

1086227

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.549

High

1157407

KI18A
Kinesin-like protein KIF18A

1

0

High-throughput

0.513

High

1157411

KIFA3
Kinesin-associated protein 3

1

0

High-throughput

0.513

High

1157416

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.513

High

1157417

PAAF1
Proteasomal ATPase-associated factor 1

1

0

High-throughput

0.513

High

1157419

PAR6B
Partitioning defective 6 homolog beta

1

0

High-throughput

0.513

High

422174

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

241801

PRKN
E3 ubiquitin-protein ligase parkin

1

1

Small-scale

0.479

High

373951

RASN
GTPase NRas

1

2

High-throughput

0.479

High

374626

RASH
GTPase HRas

1

2

High-throughput

0.479

High

375557

RASK
GTPase KRas

1

2

High-throughput

0.479

High

396198

ESR1
Estrogen receptor

1

2

High-throughput

0.479

High

520090

ANDR
Androgen receptor

1

2

High-throughput

0.479

High

931527

RD23A
UV excision repair protein RAD23 homolog A

1

1

Small-scale

0.479

High

958647

CSN2
COP9 signalosome complex subunit 2

1

3

Small-scale

0.479

High

347727

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

385786

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

487360

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

718821

CCND2
G1/S-specific cyclin-D2

1

0

Small-scale

0.458

High

777291

AHR
Aryl hydrocarbon receptor

1

0

Small-scale

0.458

High

791420

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

841013

FRK
Tyrosine-protein kinase FRK

1

0

High-throughput

0.458

High

919995

PLK1
Serine/threonine-protein kinase PLK1

1

0

High-throughput

0.458

High

928691

PMS2
Mismatch repair endonuclease PMS2

1

0

High-throughput

0.458

High

1050431

UBE3A
Ubiquitin-protein ligase E3A

1

0

High-throughput

0.458

High

1115683

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

0

High-throughput

0.458

High

1157403

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1157409

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

0

High-throughput

0.458

High

1157422

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

507206

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

2

Small-scale

0.445

High

1157410

ESR2
Estrogen receptor beta

1

2

High-throughput

0.437

High

397961

ANGI
Angiogenin

1

0

High-throughput

0.426

High

413921

P53
Cellular tumor antigen p53

1

0

Small-scale

0.426

High

1136896

ABRX2
BRISC complex subunit Abraxas 2

1

0

Small-scale

0.426

High

1157400

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1157402

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.426

High

1157405

LNX2
Ligand of Numb protein X 2

1

0

High-throughput

0.292

High

1157412

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.282

High

239836

PCDH7
Protocadherin-7

1

0

High-throughput

0.279

Low

832312

ID1
DNA-binding protein inhibitor ID-1

1

0

High-throughput

0.279

Low

1157398

CCD92
Coiled-coil domain-containing protein 92

1

0

High-throughput

0.279

Low

1157401

RNH2B
Ribonuclease H2 subunit B

1

0

High-throughput

0.279

Low

1157406

FA24B
Protein FAM24B

1

0

High-throughput

0.279

Low

1157423

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

0

High-throughput

0.279

Low

301438

WFS1
Wolframin

1

0

High-throughput

0.268

Low

890961

NDUV1
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

1

0

High-throughput

0.268

Low

106005

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

353358

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

372136

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.249

Low

389397

FINC
Fibronectin

1

0

High-throughput

0.249

Low

418157

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

1099940

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.249

Low

1114846

CUL4A
Cullin-4A

1

0

High-throughput

0.249

Low

1136642

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

0

High-throughput

0.249

Low

1157404

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1157413

RITA1
RBPJ-interacting and tubulin-associated protein 1

1

0

Small-scale

0.249

Low

1157414

UHRF2
E3 ubiquitin-protein ligase UHRF2

1

0

Small-scale

0.249

Low

1157420

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

1

0

Small-scale

0.249

Low

1157425

RNF11
RING finger protein 11

1

0

Small-scale

0.249

Low

1157399

TMM31
Transmembrane protein 31

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025