Protein: HMOX1
Heme oxygenase 1 (HO-1) (EC 1.14.14.18) [Cleaved into: Heme oxygenase 1 soluble form]

Gene: HMOX1
Organism: Homo sapiens
Interactions: 126
UniProt ID: P09601

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001935 - endothelial cell proliferation
GO:0002246 - wound healing involved in inflammatory response
GO:0002686 - negative regulation of leukocyte migration
GO:0004392 - heme oxygenase (decyclizing) activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

452235

CGT
2-hydroxyacylsphingosine 1-beta-galactosyltransferase

3

1

High-throughput

0.667

High

452298

SRPRB
Signal recognition particle receptor subunit beta

3

3

High-throughput

0.667

High

452300

TX264
Testis-expressed protein 264

3

1

High-throughput

0.667

High

452196

HLAC
HLA class I histocompatibility antigen, C alpha chain

2

1

High-throughput

0.611

High

452211

CY561
Transmembrane ascorbate-dependent reductase CYB561

2

2

High-throughput

0.606

High

452234

STX1A
Syntaxin-1A

2

2

High-throughput

0.606

High

452237

AR13B
ADP-ribosylation factor-like protein 13B

2

3

High-throughput

0.606

High

452238

CYBR1
Plasma membrane ascorbate-dependent reductase CYBRD1

2

2

High-throughput

0.606

High

452239

F209A
Protein FAM209A

2

1

High-throughput

0.606

High

452263

F210B
Protein FAM210B, mitochondrial

2

1

High-throughput

0.606

High

452278

ELOV4
Very long chain fatty acid elongase 4

2

5

High-throughput

0.606

High

452279

ELOV6
Very long chain fatty acid elongase 6

2

5

High-throughput

0.606

High

452285

ELOV5
Very long chain fatty acid elongase 5

2

5

High-throughput

0.606

High

452293

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

3

High-throughput

0.606

High

452265

CDK15
Cyclin-dependent kinase 15

2

0

High-throughput

0.602

High

452275

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

2

0

High-throughput

0.602

High

216652

CREB3
Cyclic AMP-responsive element-binding protein 3

2

1

High-throughput

0.590

High

452292

DD19B
ATP-dependent RNA helicase DDX19B

2

0

High-throughput

0.585

High

238219

MOT2
Monocarboxylate transporter 2

2

0

High-throughput

0.580

High

258390

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

2

0

High-throughput

0.580

High

452224

PDZ1I
PDZK1-interacting protein 1

2

0

High-throughput

0.580

High

452232

MSMO1
Methylsterol monooxygenase 1

2

0

High-throughput

0.580

High

452248

JAGN1
Protein jagunal homolog 1

2

0

High-throughput

0.580

High

452252

F174A
Membrane protein FAM174A

2

0

High-throughput

0.580

High

452261

T4S19
Transmembrane 4 L6 family member 19

2

0

High-throughput

0.580

High

452264

TLCD4
TLC domain-containing protein 4

2

0

High-throughput

0.580

High

452274

SC11C
Signal peptidase complex catalytic subunit SEC11C

2

0

High-throughput

0.580

High

452288

C5AR2
C5a anaphylatoxin chemotactic receptor 2

2

5

High-throughput

0.574

High

452246

CD20B
Cell division cycle protein 20 homolog B

2

2

High-throughput

0.558

High

452198

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

1

High-throughput

0.553

High

452228

AQP6
Aquaporin-6

2

1

High-throughput

0.553

High

452253

GP152
Probable G-protein coupled receptor 152

2

11

High-throughput

0.553

High

452270

CRUM3
Protein crumbs homolog 3

2

1

High-throughput

0.553

High

452283

TM14B
Transmembrane protein 14B

2

1

High-throughput

0.553

High

452195

HMOX1
Heme oxygenase 1

1

0

Small-scale

0.546

High

452284

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.543

High

452205

PE2R4
Prostaglandin E2 receptor EP4 subtype

1

3

High-throughput

0.541

High

452212

TERF1
Telomeric repeat-binding factor 1

1

1

High-throughput

0.541

High

452267

SMO
Protein smoothened

1

1

High-throughput

0.541

High

452256

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

0

Small-scale

0.537

High

125960

UPK1A
Uroplakin-1a

1

2

High-throughput

0.536

High

215798

G6PT1
Glucose-6-phosphate exchanger SLC37A4

1

1

High-throughput

0.536

High

295707

B3GA3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

1

1

High-throughput

0.536

High

326012

TSN15
Tetraspanin-15

1

1

High-throughput

0.536

High

452199

DHB1
17-beta-hydroxysteroid dehydrogenase type 1

1

1

High-throughput

0.536

High

452202

ACHB2
Neuronal acetylcholine receptor subunit beta-2

1

1

High-throughput

0.536

High

452206

HPCL1
Hippocalcin-like protein 1

1

1

High-throughput

0.536

High

452209

PTSS1
Phosphatidylserine synthase 1

1

1

High-throughput

0.536

High

452214

NCS1
Neuronal calcium sensor 1

1

1

High-throughput

0.536

High

452221

TAP1
Antigen peptide transporter 1

1

2

High-throughput

0.536

High

452243

PCAT2
Lysophosphatidylcholine acyltransferase 2

1

3

High-throughput

0.536

High

452245

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

4

High-throughput

0.536

High

452259

CCD47
PAT complex subunit CCDC47

1

1

High-throughput

0.536

High

452268

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

1

High-throughput

0.536

High

452271

DERL1
Derlin-1

1

1

High-throughput

0.536

High

452272

PTSS2
Phosphatidylserine synthase 2

1

1

High-throughput

0.536

High

452287

STIM2
Stromal interaction molecule 2

1

2

High-throughput

0.536

High

452290

PHF11
PHD finger protein 11

1

1

High-throughput

0.536

High

452296

RN115
E3 ubiquitin-protein ligase RNF115

1

3

High-throughput

0.536

High

382236

ARLY
Argininosuccinate lyase

1

0

High-throughput

0.518

High

155516

TNPO2
Transportin-2

1

0

High-throughput

0.513

High

259405

NIPS2
Protein NipSnap homolog 2

1

0

High-throughput

0.513

High

452201

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.513

High

452210

AGRE5
Adhesion G protein-coupled receptor E5

1

0

High-throughput

0.513

High

452213

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

452216

SSBP2
Single-stranded DNA-binding protein 2

1

0

High-throughput

0.513

High

452217

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.513

High

452219

GCYA1
Guanylate cyclase soluble subunit alpha-1

1

0

High-throughput

0.513

High

452240

PLPP4
Phospholipid phosphatase 4

1

0

High-throughput

0.513

High

452241

NIPA3
Magnesium transporter NIPA3

1

0

High-throughput

0.513

High

452247

CERS3
Ceramide synthase 3

1

0

High-throughput

0.513

High

452257

PIGT
GPI transamidase component PIG-T

1

0

High-throughput

0.513

High

452258

T106A
Transmembrane protein 106A

1

0

High-throughput

0.513

High

452260

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.513

High

452262

BSCL2
Seipin

1

0

High-throughput

0.513

High

452266

PIGS
GPI transamidase component PIG-S

1

0

High-throughput

0.513

High

452273

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

0

High-throughput

0.513

High

452281

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.513

High

452294

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.513

High

452223

ILF3
Interleukin enhancer-binding factor 3

1

0

Small-scale

0.493

High

452204

CCR1
C-C chemokine receptor type 1

1

3

High-throughput

0.489

High

452207

CXA8
Gap junction alpha-8 protein

1

1

High-throughput

0.489

High

452226

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

7

High-throughput

0.489

High

359589

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

2

High-throughput

0.481

High

452295

TMX2
Thioredoxin-related transmembrane protein 2

1

2

High-throughput

0.481

High

204958

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

348479

RASN
GTPase NRas

1

6

High-throughput

0.479

High

349818

RASK
GTPase KRas

1

6

High-throughput

0.479

High

452203

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

1

Small-scale

0.479

High

452215

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.479

High

452218

TIAR
Nucleolysin TIAR

1

1

Small-scale

0.479

High

452229

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

2

Small-scale

0.479

High

452250

RN149
E3 ubiquitin-protein ligase RNF149

1

4

High-throughput

0.479

High

452286

RN181
E3 ubiquitin-protein ligase RNF181

1

1

Small-scale

0.479

High

452291

FZR1
Fizzy-related protein homolog

1

1

High-throughput

0.479

High

452251

TMIE
Transmembrane inner ear expressed protein

1

0

High-throughput

0.460

High

452299

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

1

0

High-throughput

0.460

High

167813

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

199079

SIAH2
E3 ubiquitin-protein ligase SIAH2

1

0

Small-scale

0.458

High

452197

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

452200

ZSC20
Zinc finger and SCAN domain-containing protein 20

1

0

High-throughput

0.458

High

452208

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

452220

NRG1
Pro-neuregulin-1, membrane-bound isoform

1

0

High-throughput

0.458

High

452222

PPID
Peptidyl-prolyl cis-trans isomerase D

1

0

High-throughput

0.458

High

452225

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

0

Small-scale

0.458

High

452227

SQSTM
Sequestosome-1

1

0

Small-scale

0.458

High

452231

ELAV1
ELAV-like protein 1

1

0

Small-scale

0.458

High

452254

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

0

High-throughput

0.458

High

452255

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

1

0

Small-scale

0.458

High

452249

KASH5
Protein KASH5

1

1

High-throughput

0.439

High

452280

SAR1A
Small COPII coat GTPase SAR1A

1

3

High-throughput

0.439

High

452289

ACHA9
Neuronal acetylcholine receptor subunit alpha-9

1

1

High-throughput

0.437

High

452230

CASP8
Caspase-8

1

0

High-throughput

0.426

High

452233

NF2L2
Nuclear factor erythroid 2-related factor 2

1

0

High-throughput

0.426

High

452242

CLC4G
C-type lectin domain family 4 member G

1

2

Small-scale

0.407

High

452276

LRC27
Leucine-rich repeat-containing protein 27

2

0

High-throughput

0.328

High

452277

S39A8
Metal cation symporter ZIP8

2

0

High-throughput

0.328

High

452282

TB22B
TBC1 domain family member 22B

2

0

High-throughput

0.328

High

452297

PCDC2
Protocadherin alpha-C2

2

0

High-throughput

0.328

High

452244

CPLX4
Complexin-4

2

0

High-throughput

0.316

High

239729

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.279

Low

245301

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.279

Low

303634

OR2A4
Olfactory receptor 2A4

1

0

High-throughput

0.279

Low

452269

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.279

Low

452236

SOAT
Sodium-dependent organic anion transporter

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024