Protein: MORC2
ATPase MORC2 (EC 3.6.1.-) (MORC family CW-type zinc finger protein 2) (Zinc finger CW-type coiled-coil domain protein 1)

Gene: MORC2
Organism: Homo sapiens
Interactions: 88
UniProt ID: Q9Y6X9

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0000792 - heterochromatin
GO:0003682 - chromatin binding
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1290322

MORC1
MORC family CW-type zinc finger protein 1

3

5

High-throughput

0.861

High

1491868

MORC2
ATPase MORC2

2

6

Small-scale

0.789

High

1128169

DHX8
ATP-dependent RNA helicase DHX8

4

2

High-throughput

0.694

High

487948

PARP1
Poly [ADP-ribose] polymerase 1

3

7

Small-scale

0.670

High

999018

H31
Histone H3.1

3

7

Small-scale

0.640

High

1100601

TIF1B
Transcription intermediary factor 1-beta

2

4

Small-scale

0.634

High

1429653

NAT10
RNA cytidine acetyltransferase

2

0

Small-scale

0.598

High

981212

H2B1C
Histone H2B type 1-C/E/F/G/I

2

5

High-throughput

0.584

High

1133772

NFIX
Nuclear factor 1 X-type

2

8

High-throughput

0.584

High

397355

ESR1
Estrogen receptor

2

9

High-throughput

0.571

High

1312395

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

2

Small-scale

0.561

High

1454049

SENP1
Sentrin-specific protease 1

1

2

Small-scale

0.561

High

959686

MAX
Protein max

1

2

High-throughput

0.536

High

1113041

CUL2
Cullin-2

1

2

High-throughput

0.536

High

1120421

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

1

High-throughput

0.536

High

1435579

SH24A
SH2 domain-containing protein 4A

1

1

High-throughput

0.515

High

1405081

SORT
Sortilin

1

0

High-throughput

0.513

High

508932

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.501

High

191424

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

0

High-throughput

0.493

High

963554

B2MG
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]

1

0

High-throughput

0.493

High

1389535

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

1

3

High-throughput

0.489

High

129836

CBX4
E3 SUMO-protein ligase CBX4

1

3

Small-scale

0.479

High

143365

NFIB
Nuclear factor 1 B-type

1

8

High-throughput

0.479

High

191189

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

2

High-throughput

0.479

High

243460

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.479

High

260668

BRD4
Bromodomain-containing protein 4

1

3

High-throughput

0.479

High

331457

KI20A
Kinesin-like protein KIF20A

1

4

High-throughput

0.479

High

346578

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

5

High-throughput

0.479

High

401790

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.479

High

412914

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

474419

NFIC
Nuclear factor 1 C-type

1

9

High-throughput

0.479

High

559557

XRCC5
X-ray repair cross-complementing protein 5

1

2

Small-scale

0.479

High

590170

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

675744

TYY1
Transcriptional repressor protein YY1

1

2

High-throughput

0.479

High

685404

PAX6
Paired box protein Pax-6

1

5

High-throughput

0.479

High

697007

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

769656

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.479

High

834108

HNF4A
Hepatocyte nuclear factor 4-alpha

1

6

High-throughput

0.479

High

855548

ATRX
Transcriptional regulator ATRX

1

3

Small-scale

0.479

High

883752

CENPA
Histone H3-like centromeric protein A

1

7

High-throughput

0.479

High

993840

UBC9
SUMO-conjugating enzyme UBC9

1

1

Small-scale

0.479

High

998144

CSK21
Casein kinase II subunit alpha

1

1

Small-scale

0.479

High

1017342

H33
Histone H3.3

1

7

High-throughput

0.479

High

1024975

VIGLN
Vigilin

1

2

High-throughput

0.479

High

1088140

NFIA
Nuclear factor 1 A-type

1

8

High-throughput

0.479

High

1097657

CBX3
Chromobox protein homolog 3

1

3

High-throughput

0.479

High

1133081

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

3

Small-scale

0.479

High

1142053

EEA1
Early endosome antigen 1

1

5

High-throughput

0.479

High

1144520

NONO
Non-POU domain-containing octamer-binding protein

1

1

Small-scale

0.479

High

1145572

RBBP5
Retinoblastoma-binding protein 5

1

2

High-throughput

0.479

High

1207469

HABP4
Intracellular hyaluronan-binding protein 4

1

2

High-throughput

0.479

High

1256331

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

1271635

DHX30
ATP-dependent RNA helicase DHX30

1

3

Small-scale

0.479

High

1277060

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

3

High-throughput

0.479

High

1314508

SLX4
Structure-specific endonuclease subunit SLX4

1

4

High-throughput

0.479

High

1335131

SERB1
SERPINE1 mRNA-binding protein 1

1

2

High-throughput

0.479

High

1339080

NUP43
Nucleoporin Nup43

1

3

High-throughput

0.479

High

1367731

ESR2
Estrogen receptor beta

1

9

High-throughput

0.479

High

1368707

KAT6A
Histone acetyltransferase KAT6A

1

4

High-throughput

0.479

High

1401479

CIC
Protein capicua homolog

1

3

High-throughput

0.479

High

1418664

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

2

High-throughput

0.479

High

1454788

HECW2
E3 ubiquitin-protein ligase HECW2

1

2

High-throughput

0.479

High

1459516

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1491860

NCOA3
Nuclear receptor coactivator 3

1

1

Small-scale

0.479

High

437409

K2C8
Keratin, type II cytoskeletal 8

1

0

High-throughput

0.458

High

630122

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

697315

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

703224

TEAD1
Transcriptional enhancer factor TEF-1

1

0

High-throughput

0.458

High

800201

COIL
Coilin

1

0

High-throughput

0.458

High

873358

COPD
Coatomer subunit delta

1

0

Small-scale

0.458

High

997584

TBB4B
Tubulin beta-4B chain

1

0

Small-scale

0.458

High

1026614

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

1338463

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

1360137

NALP7
NACHT, LRR and PYD domains-containing protein 7

1

0

High-throughput

0.458

High

1393892

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1414641

DDX23
Probable ATP-dependent RNA helicase DDX23

1

0

High-throughput

0.458

High

1458778

NXF1
Nuclear RNA export factor 1

1

0

High-throughput

0.458

High

1461321

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.458

High

1491286

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

1491703

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

1

High-throughput

0.445

High

1448608

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

1453788

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

0

High-throughput

0.426

High

1491501

RBM7
RNA-binding protein 7

1

0

High-throughput

0.426

High

1491764

SNX9
Sorting nexin-9

1

0

High-throughput

0.426

High

887397

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.391

High

1180764

LETM2
LETM1 domain-containing protein LETM2, mitochondrial

1

0

High-throughput

0.232

Low

1350795

MO2R1
Cell surface glycoprotein CD200 receptor 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025