Protein: FXRD2
FAD-dependent oxidoreductase domain-containing protein 2 (Endoplasmic reticulum flavoprotein associated with degradation)

Gene: FXRD2, FOXRED2
Organism: Homo sapiens
Interactions: 102
UniProt ID: Q8IWF2

Gene Ontology (top 5):
GO:0004497 - monooxygenase activity
GO:0005788 - endoplasmic reticulum lumen
GO:0036503 - ERAD pathway
GO:0050660 - flavin adenine dinucleotide binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1310039

SE1L1
Protein sel-1 homolog 1

4

0

Small-scale

0.674

High

1310037

TXD16
Thioredoxin domain-containing protein 16

4

0

High-throughput

0.667

High

698856

CALX
Calnexin

2

2

High-throughput

0.628

High

1310014

ERLEC
Endoplasmic reticulum lectin 1

2

1

High-throughput

0.628

High

170855

CLGN
Calmegin

2

2

High-throughput

0.601

High

1105504

OS9
Protein OS-9

2

1

Small-scale

0.601

High

354357

TOM40
Mitochondrial import receptor subunit TOM40 homolog

2

2

High-throughput

0.574

High

1310038

DNJB9
DnaJ homolog subfamily B member 9

1

1

High-throughput

0.536

High

1310006

DJC10
DnaJ homolog subfamily C member 10

1

2

Small-scale

0.515

High

1131309

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.513

High

1310032

SDF2L
Stromal cell-derived factor 2-like protein 1

1

0

High-throughput

0.513

High

1310044

MTO1
5-taurinomethyluridine-[tRNA] synthase subunit MTO1, mitochondrial

1

0

High-throughput

0.513

High

287962

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

1

High-throughput

0.489

High

426114

PPB1
Alkaline phosphatase, placental type

1

1

High-throughput

0.489

High

449612

KLK1
Kallikrein-1

1

1

High-throughput

0.489

High

531994

PPBN
Alkaline phosphatase, germ cell type

1

1

High-throughput

0.489

High

640947

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

2

High-throughput

0.489

High

852798

VDAC2
Non-selective voltage-gated ion channel VDAC2

1

2

High-throughput

0.489

High

993433

ACTH
Actin, gamma-enteric smooth muscle

1

1

High-throughput

0.489

High

996496

ACTS
Actin, alpha skeletal muscle

1

1

High-throughput

0.489

High

1206987

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

1

1

High-throughput

0.489

High

1259326

TBA1A
Tubulin alpha-1A chain

1

1

High-throughput

0.489

High

1310008

DJB14
DnaJ homolog subfamily B member 14

1

1

High-throughput

0.489

High

1310020

TBA1C
Tubulin alpha-1C chain

1

1

High-throughput

0.489

High

1310022

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

1

High-throughput

0.489

High

1310029

KLK15
Kallikrein-15

1

1

High-throughput

0.489

High

1310035

LIN7C
Protein lin-7 homolog C

1

1

High-throughput

0.489

High

218426

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

566746

PDIA4
Protein disulfide-isomerase A4

1

1

High-throughput

0.479

High

1310015

CALR3
Calreticulin-3

1

2

High-throughput

0.479

High

1310033

FBX6
F-box only protein 6

1

1

High-throughput

0.479

High

1310011

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

0

High-throughput

0.458

High

1310041

FBX2
F-box only protein 2

1

1

High-throughput

0.445

High

1307491

RBM45
RNA-binding protein 45

2

0

High-throughput

0.328

High

1310018

MIPEP
Mitochondrial intermediate peptidase

2

0

High-throughput

0.328

High

1310042

FEM1B
Protein fem-1 homolog B

2

0

High-throughput

0.328

High

976833

LCN6
Epididymal-specific lipocalin-6

2

0

High-throughput

0.313

High

1310009

CA054
Uncharacterized protein C1orf54

2

0

High-throughput

0.313

High

61546

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.279

Low

166680

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

1

0

High-throughput

0.279

Low

168429

NCTR3
Natural cytotoxicity triggering receptor 3

1

0

High-throughput

0.279

Low

168718

CSKP
Peripheral plasma membrane protein CASK

1

0

High-throughput

0.279

Low

224500

PI15
Peptidase inhibitor 15

1

0

High-throughput

0.279

Low

245719

GANP
Germinal-center associated nuclear protein

1

0

High-throughput

0.279

Low

282204

USH2A
Usherin

1

0

High-throughput

0.279

Low

342615

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.279

Low

388725

C1QB
Complement C1q subcomponent subunit B

1

0

High-throughput

0.279

Low

436930

K1C18
Keratin, type I cytoskeletal 18

1

0

High-throughput

0.279

Low

567912

PRG2
Bone marrow proteoglycan

1

0

High-throughput

0.279

Low

600622

NAGAB
Alpha-N-acetylgalactosaminidase

1

0

High-throughput

0.279

Low

637617

FLNA
Filamin-A

1

0

High-throughput

0.279

Low

647375

IDS
Iduronate 2-sulfatase

1

0

High-throughput

0.279

Low

656011

CAH6
Carbonic anhydrase 6

1

0

High-throughput

0.279

Low

693833

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.279

Low

876266

NMU
Neuromedin-U [Cleaved into: Neuromedin precursor-related peptide 36

1

0

High-throughput

0.279

Low

880034

DNSL1
Deoxyribonuclease-1-like 1

1

0

High-throughput

0.279

Low

894883

EMD
Emerin

1

0

High-throughput

0.279

Low

901920

RAB9A
Ras-related protein Rab-9A

1

0

High-throughput

0.279

Low

903619

GALK1
Galactokinase

1

0

High-throughput

0.279

Low

935762

MFAP4
Microfibril-associated glycoprotein 4

1

0

High-throughput

0.279

Low

1008224

PRKDC
DNA-dependent protein kinase catalytic subunit

1

0

High-throughput

0.279

Low

1022087

TSG6
Tumor necrosis factor-inducible gene 6 protein

1

0

High-throughput

0.279

Low

1030188

IL5RA
Interleukin-5 receptor subunit alpha

1

0

High-throughput

0.279

Low

1034770

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.279

Low

1153188

HERC1
Probable E3 ubiquitin-protein ligase HERC1

1

0

High-throughput

0.279

Low

1191873

TBB8
Tubulin beta-8 chain

1

0

High-throughput

0.279

Low

1208932

DCA10
DDB1- and CUL4-associated factor 10

1

0

High-throughput

0.279

Low

1236105

FSTL4
Follistatin-related protein 4

1

0

High-throughput

0.279

Low

1248556

LYPD4
Ly6/PLAUR domain-containing protein 4

1

0

High-throughput

0.279

Low

1309125

MISP
Mitotic interactor and substrate of PLK1

1

0

High-throughput

0.279

Low

1310005

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

1310007

FIBIN
Fin bud initiation factor homolog

1

0

High-throughput

0.279

Low

1310010

MADD
MAP kinase-activating death domain protein

1

0

High-throughput

0.279

Low

1310012

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.279

Low

1310017

SORT
Sortilin

1

0

High-throughput

0.279

Low

1310019

NIPS1
Protein NipSnap homolog 1

1

0

High-throughput

0.279

Low

1310021

MIC25
MICOS complex subunit MIC25

1

0

High-throughput

0.279

Low

1310023

UBAC1
Ubiquitin-associated domain-containing protein 1

1

0

High-throughput

0.279

Low

1310024

NDUF3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3

1

0

High-throughput

0.279

Low

1310025

KPCD2
Serine/threonine-protein kinase D2

1

0

High-throughput

0.279

Low

1310026

DPY30
Protein dpy-30 homolog

1

0

High-throughput

0.279

Low

1310027

CLPB
Mitochondrial disaggregase

1

0

High-throughput

0.279

Low

1310028

CAD23
Cadherin-23

1

0

High-throughput

0.279

Low

1310030

SAV1
Protein salvador homolog 1

1

0

High-throughput

0.279

Low

1310040

DIC
Mitochondrial dicarboxylate carrier

1

0

High-throughput

0.279

Low

1310043

SARDH
Sarcosine dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

293978

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

417560

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

Small-scale

0.249

Low

1161137

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.249

Low

1248996

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1254534

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1310013

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.249

Low

1310016

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.249

Low

1310031

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.249

Low

1310034

T106B
Transmembrane protein 106B

1

0

High-throughput

0.249

Low

58734

PTPC1
Protein tyrosine phosphatase domain-containing protein 1

1

0

High-throughput

0.232

Low

388543

CRP

1

0

High-throughput

0.232

Low

399456

TRGV3
T cell receptor gamma variable 3

1

0

High-throughput

0.232

Low

1136914

ABRX2
BRISC complex subunit Abraxas 2

1

0

High-throughput

0.232

Low

1251879

CCNI2
Cyclin-I2

1

0

High-throughput

0.232

Low

1308257

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

0

High-throughput

0.232

Low

1310036

BABA2
BRISC and BRCA1-A complex member 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025