Protein: ARGL1
Arginine and glutamate-rich protein 1

Gene: ARGL1, ARGLU1
Organism: Homo sapiens
Interactions: 178
UniProt ID: Q9NWB6

Gene Ontology (top 5):
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0003713 - transcription coactivator activity
GO:0005654 - nucleoplasm
GO:0005694 - chromosome
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1006750

SRPK2
SRSF protein kinase 2

3

3

High-throughput

0.677

High

1418620

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

3

3

High-throughput

0.650

High

1239680

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

3

0

High-throughput

0.638

High

1451165

PUF60
Poly(U)-binding-splicing factor PUF60

2

1

High-throughput

0.611

High

1451157

ARGL1
Arginine and glutamate-rich protein 1

2

2

High-throughput

0.600

High

898855

RL14
Large ribosomal subunit protein eL14

2

0

High-throughput

0.585

High

285495

EED
Polycomb protein EED

2

1

High-throughput

0.584

High

1135131

CUL7
Cullin-7

2

1

High-throughput

0.584

High

1143283

PLEC
Plectin

2

1

High-throughput

0.584

High

480323

RU1C
U1 small nuclear ribonucleoprotein C

2

0

High-throughput

0.576

High

1198673

NCBP3
Nuclear cap-binding protein subunit 3

2

0

High-throughput

0.576

High

397062

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

473127

RU17
U1 small nuclear ribonucleoprotein 70 kDa

2

3

High-throughput

0.571

High

537999

HSP7C
Heat shock cognate 71 kDa protein

2

1

High-throughput

0.571

High

541716

FGFR1
Fibroblast growth factor receptor 1

2

2

High-throughput

0.571

High

1109671

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

2

1

High-throughput

0.571

High

1402611

SRPK1
SRSF protein kinase 1

1

3

High-throughput

0.550

High

463800

LYN
Tyrosine-protein kinase Lyn

2

0

High-throughput

0.547

High

717356

PEBP1
Phosphatidylethanolamine-binding protein 1

2

0

High-throughput

0.547

High

1144552

PTPRR
Receptor-type tyrosine-protein phosphatase R

2

0

High-throughput

0.547

High

286504

WBP4
WW domain-binding protein 4

1

2

Small-scale

0.541

High

1451174

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.537

High

301240

RL1D1
Ribosomal L1 domain-containing protein 1

1

1

High-throughput

0.536

High

431259

LA
Lupus La protein

1

1

High-throughput

0.536

High

576576

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

2

High-throughput

0.536

High

765934

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.536

High

842874

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

3

High-throughput

0.536

High

883712

CENPA
Histone H3-like centromeric protein A

1

1

High-throughput

0.536

High

889823

CLK3
Dual specificity protein kinase CLK3

1

2

High-throughput

0.536

High

890602

RBP2
E3 SUMO-protein ligase RanBP2

1

1

High-throughput

0.536

High

1061178

SRSF1
Serine/arginine-rich splicing factor 1

1

3

High-throughput

0.536

High

1062133

SRSF4
Serine/arginine-rich splicing factor 4

1

2

High-throughput

0.536

High

1062675

DHX9
ATP-dependent RNA helicase A

1

4

High-throughput

0.536

High

1160107

SRSF7
Serine/arginine-rich splicing factor 7

1

3

High-throughput

0.536

High

1245425

ZC3HE
Zinc finger CCCH domain-containing protein 14

1

1

High-throughput

0.536

High

1368803

EZH1
Histone-lysine N-methyltransferase EZH1

1

1

High-throughput

0.536

High

1415555

GNL3
Guanine nucleotide-binding protein-like 3

1

1

High-throughput

0.536

High

1451070

RBM22
Pre-mRNA-splicing factor RBM22

1

1

High-throughput

0.536

High

1451166

ACINU
Apoptotic chromatin condensation inducer in the nucleus

1

4

High-throughput

0.536

High

1029956

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.518

High

801557

HSPA9
Stress-70 protein, mitochondrial

1

2

High-throughput

0.515

High

134886

SAP18
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.513

High

158673

TYB4Y
Thymosin beta-4, Y-chromosomal

1

0

High-throughput

0.513

High

169213

QCR10
Cytochrome b-c1 complex subunit 10

1

0

High-throughput

0.513

High

183522

CASC3
Protein CASC3

1

0

High-throughput

0.513

High

257981

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

1

0

High-throughput

0.513

High

277960

SH3L1
Adapter SH3BGRL

1

0

High-throughput

0.513

High

485746

RU2A
U2 small nuclear ribonucleoprotein A'

1

0

High-throughput

0.513

High

488084

IFI6
Interferon alpha-inducible protein 6

1

0

High-throughput

0.513

High

578725

GLNA
Glutamine synthetase

1

0

High-throughput

0.513

High

859477

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.513

High

873795

CD151
CD151 antigen

1

0

High-throughput

0.513

High

1016383

SERF2
Small EDRK-rich factor 2

1

0

High-throughput

0.513

High

1023629

CYC
Cytochrome c

1

0

High-throughput

0.513

High

1116784

AAMP
Angio-associated migratory cell protein

1

0

High-throughput

0.513

High

1130201

SMC1A
Structural maintenance of chromosomes protein 1A

1

0

High-throughput

0.513

High

1134550

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

0

High-throughput

0.513

High

1154298

UB2V2
Ubiquitin-conjugating enzyme E2 variant 2

1

0

High-throughput

0.513

High

1157960

DDB1
DNA damage-binding protein 1

1

0

High-throughput

0.513

High

1187931

KR197
Keratin-associated protein 19-7

1

0

High-throughput

0.513

High

1328848

COMD1
COMM domain-containing protein 1

1

0

High-throughput

0.513

High

1404452

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.513

High

1411878

TCAL7
Transcription elongation factor A protein-like 7

1

0

High-throughput

0.513

High

1429665

COMD4
COMM domain-containing protein 4

1

0

High-throughput

0.513

High

1432368

PININ
Pinin

1

0

High-throughput

0.513

High

1446390

IL26
Interleukin-26

1

0

High-throughput

0.513

High

1447814

DDX21
Nucleolar RNA helicase 2

1

0

High-throughput

0.513

High

1451158

NHP2
H/ACA ribonucleoprotein complex subunit 2

1

0

High-throughput

0.513

High

1451159

BCLF1
Bcl-2-associated transcription factor 1

1

0

High-throughput

0.513

High

1451169

TPX2
Targeting protein for Xklp2

1

0

High-throughput

0.513

High

1311292

CHERP
Calcium homeostasis endoplasmic reticulum protein

1

1

High-throughput

0.508

High

1095188

RED
Protein Red

1

0

High-throughput

0.493

High

1346654

VANG1
Vang-like protein 1

1

1

High-throughput

0.489

High

1451168

VANG2
Vang-like protein 2

1

1

High-throughput

0.489

High

162716

ANM5
Protein arginine N-methyltransferase 5

1

0

High-throughput

0.486

High

423307

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

238960

DHX16
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

1

3

High-throughput

0.479

High

260529

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.479

High

331362

KI20A
Kinesin-like protein KIF20A

1

3

High-throughput

0.479

High

373295

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

406715

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

412698

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

414721

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

685752

U2AF2
Splicing factor U2AF 65 kDa subunit

1

3

High-throughput

0.479

High

1017253

H33
Histone H3.3

1

1

High-throughput

0.479

High

1035949

KIF23
Kinesin-like protein KIF23

1

2

High-throughput

0.479

High

1138100

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.479

High

1155826

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.479

High

1290767

ZCH18
Zinc finger CCCH domain-containing protein 18

1

1

High-throughput

0.479

High

1338998

NUP43
Nucleoporin Nup43

1

2

High-throughput

0.479

High

1340821

COP1
E3 ubiquitin-protein ligase COP1

1

1

High-throughput

0.479

High

1389914

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

1

High-throughput

0.479

High

1414592

DDX23
Probable ATP-dependent RNA helicase DDX23

1

1

High-throughput

0.479

High

1431837

SLK
STE20-like serine/threonine-protein kinase

1

11

High-throughput

0.479

High

1436504

ECT2
Protein ECT2

1

1

High-throughput

0.479

High

1450900

RNF12
E3 ubiquitin-protein ligase RLIM

1

1

High-throughput

0.479

High

1451161

MTCH1
Mitochondrial carrier homolog 1

1

1

High-throughput

0.479

High

1451162

DNJB4
DnaJ homolog subfamily B member 4

1

2

High-throughput

0.479

High

1451163

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

1451170

FBW1A
F-box/WD repeat-containing protein 1A

1

2

High-throughput

0.479

High

1451173

MTCH2
Mitochondrial carrier homolog 2

1

1

High-throughput

0.479

High

124516

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.458

High

157916

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

223372

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

326066

UBR5
E3 ubiquitin-protein ligase UBR5

1

0

High-throughput

0.458

High

343076

HERC2
E3 ubiquitin-protein ligase HERC2

1

0

High-throughput

0.458

High

556374

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

564447

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.458

High

589849

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

668042

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.458

High

696668

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

769335

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

831523

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

860625

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.458

High

879528

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

905198

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

971173

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

980431

H4
Histone H4

1

0

High-throughput

0.458

High

995303

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.458

High

1026560

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

1033268

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

1045829

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1058318

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1085627

FOXO1
Forkhead box protein O1

1

0

High-throughput

0.458

High

1140935

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1146846

PCBP1
Poly(rC)-binding protein 1

1

0

High-throughput

0.458

High

1148659

SF3A2
Splicing factor 3A subunit 2

1

0

High-throughput

0.458

High

1159027

RBBP7
Histone-binding protein RBBP7

1

0

High-throughput

0.458

High

1208963

DCA10
DDB1- and CUL4-associated factor 10

1

0

High-throughput

0.458

High

1313470

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1346953

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.458

High

1388293

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.458

High

1416884

NAA15
N-alpha-acetyltransferase 15, NatA auxiliary subunit

1

0

High-throughput

0.458

High

1420958

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1433089

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

1435808

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1437223

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.458

High

1447336

ANLN
Anillin

1

0

High-throughput

0.458

High

1449226

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

911685

NCBP2
Nuclear cap-binding protein subunit 2

1

4

High-throughput

0.445

High

1145401

RNPS1
RNA-binding protein with serine-rich domain 1

1

2

High-throughput

0.445

High

533782

CLUS
Clusterin

1

0

High-throughput

0.438

High

1448492

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

991944

DYLT1
Dynein light chain Tctex-type 1

1

2

High-throughput

0.437

High

1141334

BRD3
Bromodomain-containing protein 3

1

2

High-throughput

0.437

High

1359393

DNJB3
DnaJ homolog subfamily B member 3

1

3

High-throughput

0.437

High

1451164

SEC63
Translocation protein SEC63 homolog

1

2

High-throughput

0.437

High

407721

S100B
Protein S100-B

1

0

High-throughput

0.426

High

430427

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

574491

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

0

High-throughput

0.426

High

974063

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.426

High

1437538

EAF6
Chromatin modification-related protein MEAF6

1

0

High-throughput

0.426

High

1451171

LC7L2
Putative RNA-binding protein Luc7-like 2

1

0

High-throughput

0.426

High

317091

DPM2
Dolichol phosphate-mannose biosynthesis regulatory protein

1

0

High-throughput

0.279

Low

354039

CX001
Putative transmembrane protein CXorf1

1

0

High-throughput

0.279

Low

515905

SAA1
Serum amyloid A-1 protein

1

0

High-throughput

0.279

Low

1009627

CXCL6
C-X-C motif chemokine 6

1

0

High-throughput

0.279

Low

1092825

MALL
MAL-like protein

1

0

High-throughput

0.279

Low

1093775

GAGE5
G antigen 5

1

0

High-throughput

0.279

Low

1175848

T132A
Transmembrane protein 132A

1

0

High-throughput

0.279

Low

1278365

COMD6
COMM domain-containing protein 6

1

0

High-throughput

0.279

Low

1293508

COMD2
COMM domain-containing protein 2

1

0

High-throughput

0.279

Low

1312864

GPAM1
GPALPP motifs-containing protein 1

1

0

High-throughput

0.279

Low

1360761

JPH3
Junctophilin-3

1

0

High-throughput

0.279

Low

1384727

I27L1
Interferon alpha-inducible protein 27-like protein 1

1

0

High-throughput

0.279

Low

1413564

H2AJ
Histone H2A.J

1

0

High-throughput

0.279

Low

1438301

BEX1
Protein BEX1

1

0

High-throughput

0.279

Low

1451160

PEN2
Gamma-secretase subunit PEN-2

1

0

High-throughput

0.279

Low

1451167

ANR50
Ankyrin repeat domain-containing protein 50

1

0

High-throughput

0.279

Low

1451172

CCDC9
Coiled-coil domain-containing protein 9

1

0

High-throughput

0.279

Low

1348977

ZCH10
Zinc finger CCHC domain-containing protein 10

1

0

High-throughput

0.265

Low

583345

FOLR1
Folate receptor alpha

1

0

High-throughput

0.249

Low

1135828

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

Small-scale

0.249

Low

1272680

DET1
DET1 homolog

1

0

High-throughput

0.249

Low

1332520

POC5
Centrosomal protein POC5

1

0

High-throughput

0.232

Low

1335751

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low

1337423

SRFB1
Serum response factor-binding protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025