Protein: ACSF2
Medium-chain acyl-CoA ligase ACSF2, mitochondrial (EC 6.2.1.2)

Gene: ACSF2
Organism: Homo sapiens
Interactions: 74
UniProt ID: Q96CM8

Gene Ontology (top 5):
GO:0004467 - long-chain fatty acid-CoA ligase activity
GO:0005524 - ATP binding
GO:0005759 - mitochondrial matrix
GO:0006631 - fatty acid metabolic process
GO:0006637 - acyl-CoA metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1156321

ACSM5
Acyl-coenzyme A synthetase ACSM5, mitochondrial

2

6

High-throughput

0.811

High

1286907

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

5

1

High-throughput

0.657

High

1286916

IPYR2
Inorganic pyrophosphatase 2, mitochondrial

2

1

High-throughput

0.611

High

856767

RM12
Large ribosomal subunit protein bL12m

2

0

High-throughput

0.602

High

258502

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

2

2

High-throughput

0.553

High

1169567

DG2L6
Diacylglycerol O-acyltransferase 2-like protein 6

2

1

High-throughput

0.553

High

1255396

GP152
Probable G-protein coupled receptor 152

2

4

High-throughput

0.553

High

1286918

SENP2
Sentrin-specific protease 2

2

1

High-throughput

0.553

High

216794

CREB3
Cyclic AMP-responsive element-binding protein 3

2

1

High-throughput

0.539

High

258752

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

1

2

High-throughput

0.536

High

398389

PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial

1

1

High-throughput

0.536

High

499998

CH60
60 kDa heat shock protein, mitochondrial

1

5

High-throughput

0.536

High

646435

KAD4
Adenylate kinase 4, mitochondrial

1

1

High-throughput

0.536

High

790266

THIM
3-ketoacyl-CoA thiolase, mitochondrial

1

1

High-throughput

0.536

High

1159912

FAHD1
Oxaloacetate decarboxylase, mitochondrial

1

1

High-throughput

0.536

High

1286914

LDH6B
L-lactate dehydrogenase A-like 6B

1

1

High-throughput

0.536

High

1286917

MTG2
Mitochondrial ribosome-associated GTPase 2

1

1

High-throughput

0.536

High

1286925

MRM2
rRNA methyltransferase 2, mitochondrial

1

1

High-throughput

0.536

High

1286926

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

2

High-throughput

0.536

High

272376

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

1

0

High-throughput

0.513

High

1030112

DHRS2
Dehydrogenase/reductase SDR family member 2, mitochondrial

1

0

High-throughput

0.513

High

1246517

PPTC7
Protein phosphatase PTC7 homolog

1

0

High-throughput

0.513

High

245390

RAMP3
Receptor activity-modifying protein 3

1

2

High-throughput

0.489

High

270933

KBL
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial

1

1

High-throughput

0.489

High

595559

GRAH
Granzyme H

1

6

High-throughput

0.489

High

621809

PRTN3
Myeloblastin

1

6

High-throughput

0.489

High

815413

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

2

High-throughput

0.489

High

1127497

WDR44
WD repeat-containing protein 44

1

2

High-throughput

0.489

High

1187909

RM21
Large ribosomal subunit protein bL21m

1

1

High-throughput

0.489

High

1204144

NIT1
Deaminated glutathione amidase

1

1

High-throughput

0.489

High

1252998

F174A
Membrane protein FAM174A

1

2

High-throughput

0.489

High

1266005

AQP3
Aquaporin-3

1

2

High-throughput

0.489

High

1285818

TRI43
Tripartite motif-containing protein 43

1

2

High-throughput

0.489

High

1286906

ARHGQ
Rho guanine nucleotide exchange factor 26

1

1

High-throughput

0.489

High

1286908

RT24
Small ribosomal subunit protein uS3m

1

2

High-throughput

0.489

High

1286910

RSLAB
Ras-like protein family member 10B

1

1

High-throughput

0.489

High

1286913

NPS3B
Protein NipSnap homolog 3B

1

2

High-throughput

0.489

High

1286919

S6A20
Sodium- and chloride-dependent transporter XTRP3

1

1

High-throughput

0.489

High

1286921

DIC
Mitochondrial dicarboxylate carrier

1

1

High-throughput

0.489

High

1286922

NPS3A
Protein NipSnap homolog 3A

1

2

High-throughput

0.489

High

1286924

AMACR
Alpha-methylacyl-CoA racemase

1

1

High-throughput

0.489

High

1286928

GPR45
Probable G-protein coupled receptor 45

1

2

High-throughput

0.489

High

921679

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

1

High-throughput

0.470

High

1286927

SHLB1
Endophilin-B1

1

2

High-throughput

0.470

High

1262373

MAIP1
m-AAA protease-interacting protein 1, mitochondrial

1

0

High-throughput

0.458

High

1286929

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

2

High-throughput

0.445

High

1286920

UBP40
Ubiquitin carboxyl-terminal hydrolase 40

1

3

Small-scale

0.439

High

228304

PRKN
E3 ubiquitin-protein ligase parkin

1

8

High-throughput

0.437

High

553392

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.437

High

651911

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.437

High

1171159

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.437

High

1286923

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.437

High

1065288

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

5

0

High-throughput

0.375

High

1164241

ATRAP
Type-1 angiotensin II receptor-associated protein

2

0

High-throughput

0.327

High

213274

SNG3
Synaptogyrin-3

2

0

High-throughput

0.316

High

361640

APOC1
Apolipoprotein C-I

2

0

High-throughput

0.316

High

1110051

AR13B
ADP-ribosylation factor-like protein 13B

2

0

High-throughput

0.316

High

1140494

MIC13
MICOS complex subunit MIC13

2

0

High-throughput

0.316

High

1156118

RHBD2
Rhomboid domain-containing protein 2

2

0

High-throughput

0.316

High

1163081

APOA5
Apolipoprotein A-V

2

0

High-throughput

0.316

High

1216646

CLC10
C-type lectin domain family 10 member A

2

0

High-throughput

0.316

High

1223314

CJ067
Uncharacterized protein C10orf67, mitochondrial

2

0

High-throughput

0.316

High

1224992

RDH10
Retinol dehydrogenase 10

2

0

High-throughput

0.316

High

1286909

SIG12
Sialic acid-binding Ig-like lectin 12

2

0

High-throughput

0.316

High

326341

BPNT1
3'(2'),5'-bisphosphate nucleotidase 1

1

0

High-throughput

0.279

Low

341454

FA12
Coagulation factor XII

1

0

High-throughput

0.279

Low

726353

BASI
Basigin

1

0

High-throughput

0.279

Low

1082706

RM23
Large ribosomal subunit protein uL23m

1

0

High-throughput

0.279

Low

1084754

TAZ
Tafazzin

1

0

High-throughput

0.279

Low

1286905

NUD16
U8 snoRNA-decapping enzyme

1

0

High-throughput

0.279

Low

1286911

GML
Glycosyl-phosphatidylinositol-anchored molecule-like protein

1

0

High-throughput

0.279

Low

1286912

LSMD1
N-alpha-acetyltransferase 38, NatC auxiliary subunit

1

0

High-throughput

0.279

Low

1286915

COMD5
COMM domain-containing protein 5

1

0

High-throughput

0.279

Low

559208

H15
Histone H1.5

1

0

High-throughput

0.269

Low


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Last updated: 15 Jul 2024