Protein: HPH1
Protein HPH1 (Functionally related to TCP1 protein 1) (High pH protein 1)

Gene: HPH1, FRT1
Organism: Saccharomyces cerevisiae S288C
Interactions: 62
UniProt ID: Q99332

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0031204 - post-translational protein targeting to membrane, translocation
GO:0071469 - cellular response to alkaline pH
GO:0071472 - cellular response to salt stress

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

656361

PP2B1
Serine/threonine-protein phosphatase 2B catalytic subunit A1

3

1

Small-scale

0.580

High

1060051

ADY3
Accumulates dyads protein 3

2

1

High-throughput

0.559

High

575626

PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit A2

2

1

Small-scale

0.535

High

780892

STB6
Protein STB6

2

3

High-throughput

0.535

High

820267

SSB2
Ribosome-associated molecular chaperone SSB2

2

1

High-throughput

0.504

High

1055580

YP153
Uncharacterized protein YPR153W

1

0

High-throughput

0.486

High

1403968

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.486

High

1084886

ERP3
Protein ERP3

1

1

High-throughput

0.481

High

577258

SEC63
Protein translocation protein SEC63

1

1

Small-scale

0.479

High

641406

SEC62
Translocation protein SEC62

1

1

Small-scale

0.479

High

748598

SC61A
Protein transport protein SEC61

1

1

Small-scale

0.479

High

754421

SEC66
Translocation protein SEC66

1

1

Small-scale

0.479

High

814135

HPH2
Protein HPH2

1

1

Small-scale

0.479

High

814192

SEC72
Translocation protein SEC72

1

1

Small-scale

0.479

High

1404048

HPH1
Protein HPH1

1

1

Small-scale

0.479

High

597322

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.460

High

743892

YEF3
Uncharacterized protein YEL043W

1

0

High-throughput

0.460

High

779530

YKT6
Synaptobrevin homolog YKT6

1

0

High-throughput

0.460

High

804924

LAM4
Membrane-anchored lipid-binding protein LAM4

1

0

High-throughput

0.460

High

918785

NNF2
Protein NNF2

1

0

High-throughput

0.460

High

893312

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

0

Small-scale

0.458

High

646105

KIN3
Serine/threonine-protein kinase KIN3

1

2

High-throughput

0.439

High

779819

DYHC
Dynein heavy chain, cytoplasmic

1

1

High-throughput

0.439

High

809250

END3
Actin cytoskeleton-regulatory complex protein END3

1

1

High-throughput

0.439

High

849714

FMP32
Protein FMP32, mitochondrial

1

1

High-throughput

0.439

High

858535

STB2
Protein STB2

1

3

High-throughput

0.439

High

1056307

HDA2
HDA1 complex subunit 2

1

1

High-throughput

0.439

High

580337

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.437

High

525729

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.407

High

546953

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.407

High

626555

AP1
AP-1-like transcription factor YAP1

1

0

High-throughput

0.251

Low

735694

SMY1
Kinesin-related protein SMY1

1

0

High-throughput

0.251

Low

737070

CDC3
Cell division control protein 3

1

0

High-throughput

0.251

Low

748251

VAM7
Vacuolar morphogenesis protein 7

1

0

High-throughput

0.251

Low

750813

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.251

Low

776343

MRP8
Uncharacterized protein MRP8

1

0

High-throughput

0.251

Low

776462

BLI1
Biogenesis of lysosome-related organelles complex 1 subunit BLI1

1

0

High-throughput

0.251

Low

781003

SPC42
Spindle pole body component SPC42

1

0

High-throughput

0.251

Low

781494

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.251

Low

790354

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

0

High-throughput

0.251

Low

817049

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.251

Low

817783

TSC11
Target of rapamycin complex 2 subunit TSC11

1

0

High-throughput

0.251

Low

824895

NDC80
Kinetochore protein NDC80

1

0

High-throughput

0.251

Low

829798

MAD1
Spindle assembly checkpoint component MAD1

1

0

High-throughput

0.251

Low

866087

NNF1
Kinetochore-associated protein NNF1

1

0

High-throughput

0.251

Low

866282

HMS2
Probable transcription factor HMS2

1

0

High-throughput

0.251

Low

917747

KNL1
Outer kinetochore KNL1 complex subunit SPC105

1

0

High-throughput

0.251

Low

924534

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.251

Low

924917

AF9
Protein AF-9 homolog

1

0

High-throughput

0.251

Low

1043814

RCF1
Respiratory supercomplex factor 1, mitochondrial

1

0

High-throughput

0.251

Low

1046733

SPC24
Kinetochore protein SPC24

1

0

High-throughput

0.251

Low

1056287

HDA3
HDA1 complex subunit 3

1

0

High-throughput

0.251

Low

1065591

YP216
Putative ISWI chromatin-remodeling complex subunit YPL216W

1

0

High-throughput

0.251

Low

1085024

NOT5
General negative regulator of transcription subunit 5

1

0

High-throughput

0.251

Low

798389

MTC4
Maintenance of telomere capping protein 4

1

0

High-throughput

0.249

Low

825310

MOB1
DBF2 kinase activator protein MOB1

1

0

High-throughput

0.249

Low

932271

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.249

Low

1059457

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

554077

TCPA
T-complex protein 1 subunit alpha

1

0

High-throughput

0.238

Low

1039676

NOG1
Nucleolar GTP-binding protein 1

1

0

High-throughput

0.238

Low

824606

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025