Protein: IOC3
ISWI one complex protein 3

Gene: IOC3
Organism: Saccharomyces cerevisiae S288C
Interactions: 55
UniProt ID: P43596

Gene Ontology (top 5):
GO:0006338 - chromatin remodeling
GO:0006355 - regulation of DNA-templated transcription
GO:0007062 - sister chromatid cohesion
GO:0016587 - Isw1 complex
GO:0036436 - Isw1a complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

794188

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

12

1

Small-scale

0.983

High

382172

H4
Histone H4

4

0

High-throughput

0.653

High

381147

H2B1
Histone H2B.1

3

1

High-throughput

0.650

High

850377

H3
Histone H3

4

0

Small-scale

0.648

High

419782

H2A2
Histone H2A.2

3

1

Small-scale

0.603

High

850380

HMO1
High mobility group protein 1

2

1

Small-scale

0.601

High

547876

NHP6B
Non-histone chromosomal protein 6B

2

0

High-throughput

0.563

High

850388

IOC2
ISWI one complex protein 2

2

0

High-throughput

0.551

High

850379

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.536

High

850391

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.536

High

524324

HSP71
Heat shock protein SSA1

2

2

High-throughput

0.521

High

850371

RSC8
Chromatin structure-remodeling complex protein RSC8

1

0

High-throughput

0.513

High

850373

ITC1
Imitation switch two complex protein 1

1

0

High-throughput

0.513

High

734438

BTAF1
TATA-binding protein-associated factor MOT1

1

2

High-throughput

0.489

High

381546

H2B2
Histone H2B.2

1

1

High-throughput

0.479

High

822991

ATAD2
ATPase histone chaperone YTA7

1

0

High-throughput

0.458

High

850374

H1
Histone H1

1

0

Small-scale

0.458

High

850381

IOC4
ISWI one complex protein 4

1

0

High-throughput

0.458

High

419449

H2A1
Histone H2A.1

1

1

Small-scale

0.457

High

850393

H2AZ
Histone H2A.Z

1

2

High-throughput

0.445

High

850376

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.437

High

448185

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.426

High

781755

SET3
SET domain-containing protein 3

1

0

High-throughput

0.426

High

850378

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

0

High-throughput

0.426

High

850386

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.426

High

545313

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.407

High

819072

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.407

High

850392

CAF1A
Chromatin assembly factor 1 subunit A

1

1

High-throughput

0.407

High

649980

SIN3
Transcriptional regulatory protein SIN3

2

0

High-throughput

0.324

High

826597

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.305

High

744878

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

0

High-throughput

0.282

High

814220

RV167
Reduced viability upon starvation protein 167

1

0

High-throughput

0.282

High

639030

VPS1
Vacuolar protein sorting-associated protein 1

1

0

High-throughput

0.279

Low

647791

RFA1
Replication factor A protein 1

1

0

High-throughput

0.279

Low

850375

FPK1
Flippase kinase 1

1

0

High-throughput

0.279

Low

850385

PBP4
Protein PBP4

1

0

High-throughput

0.269

Low

448979

TOP2
DNA topoisomerase 2

1

0

High-throughput

0.249

Low

557737

SRS2
ATP-dependent DNA helicase SRS2

1

0

High-throughput

0.249

Low

570058

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.249

Low

594432

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.249

Low

707432

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

709832

BMH1
Protein BMH1

1

0

High-throughput

0.249

Low

739672

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.249

Low

745787

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.249

Low

763926

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

812420

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

850372

TAF1
Transcription initiation factor TFIID subunit 1

1

0

High-throughput

0.249

Low

850383

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

850387

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

850389

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.249

Low

850390

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.249

Low

850384

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.238

Low

548778

MCM1
Pheromone receptor transcription factor

1

0

High-throughput

0.232

Low

826017

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.232

Low

850382

RCO1
Transcriptional regulatory protein RCO1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025