Protein: NRAM2
Natural resistance-associated macrophage protein 2 (NRAMP 2) (Divalent cation transporter 1) (Divalent metal transporter 1) (DMT-1) (Solute carrier family 11 member 2)

Gene: NRAM2, SLC11A2
Organism: Homo sapiens
Interactions: 109
UniProt ID: P49281

Gene Ontology (top 5):
GO:0001666 - response to hypoxia
GO:0003032 - detection of oxygen
GO:0005375 - copper ion transmembrane transporter activity
GO:0005381 - iron ion transmembrane transporter activity
GO:0005384 - manganese ion transmembrane transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

880867

NFIP1
NEDD4 family-interacting protein 1

2

1

Small-scale

0.601

High

661239

AT2B4
Plasma membrane calcium-transporting ATPase 4

2

0

High-throughput

0.576

High

698486

CALX
Calnexin

1

1

High-throughput

0.536

High

184142

RER1
Protein RER1

1

0

High-throughput

0.513

High

228072

PM34
Peroxisomal membrane protein PMP34

1

0

High-throughput

0.513

High

397589

NU1M
NADH-ubiquinone oxidoreductase chain 1

1

0

High-throughput

0.513

High

462769

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

1

0

High-throughput

0.513

High

609623

LEG3
Galectin-3

1

0

High-throughput

0.513

High

880843

CP20A
Cytochrome P450 20A1

1

0

High-throughput

0.513

High

880851

SPP2B
Signal peptide peptidase-like 2B

1

0

High-throughput

0.513

High

880877

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.513

High

360395

COX2
Cytochrome c oxidase subunit 2

1

0

Small-scale

0.506

High

281913

MPPB
Mitochondrial-processing peptidase subunit beta

1

0

High-throughput

0.493

High

880863

VPS35
Vacuolar protein sorting-associated protein 35

1

0

Small-scale

0.480

High

126505

RHOD
Rho-related GTP-binding protein RhoD

1

10

High-throughput

0.479

High

241062

PRKN
E3 ubiquitin-protein ligase parkin

1

1

Small-scale

0.479

High

466152

RHOC
Rho-related GTP-binding protein RhoC

1

7

High-throughput

0.479

High

561948

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.479

High

580929

RAC2
Ras-related C3 botulinum toxin substrate 2

1

6

High-throughput

0.479

High

861515

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

2

Small-scale

0.479

High

880824

RAC3
Ras-related C3 botulinum toxin substrate 3

1

7

High-throughput

0.479

High

880825

CDC42
Cell division control protein 42 homolog

1

7

High-throughput

0.479

High

880827

RHOA
Transforming protein RhoA

1

8

High-throughput

0.479

High

880828

RHOB
Rho-related GTP-binding protein RhoB

1

8

High-throughput

0.479

High

880829

RAC1
Ras-related C3 botulinum toxin substrate 1

1

7

High-throughput

0.479

High

880831

RHOG
Rho-related GTP-binding protein RhoG

1

6

High-throughput

0.479

High

880850

RN149
E3 ubiquitin-protein ligase RNF149

1

1

High-throughput

0.479

High

880862

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

2

Small-scale

0.479

High

880872

RHOJ
Rho-related GTP-binding protein RhoJ

1

8

High-throughput

0.479

High

880875

RHOF
Rho-related GTP-binding protein RhoF

1

9

High-throughput

0.479

High

880880

NFIP2
NEDD4 family-interacting protein 2

1

1

Small-scale

0.479

High

880887

LAMP3
Lysosome-associated membrane glycoprotein 3

1

1

High-throughput

0.479

High

374466

RASH
GTPase HRas

1

0

High-throughput

0.458

High

880820

RAB9A
Ras-related protein Rab-9A

1

0

High-throughput

0.458

High

880841

TECT3
Tectonic-3

1

0

High-throughput

0.458

High

156124

TRAD1
TRAF-type zinc finger domain-containing protein 1

1

1

High-throughput

0.445

High

603891

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.445

High

637126

CSRP1
Cysteine and glycine-rich protein 1

1

1

High-throughput

0.445

High

800461

VATA
V-type proton ATPase catalytic subunit A

1

1

High-throughput

0.445

High

880823

ZN121
Zinc finger protein 121

1

1

High-throughput

0.445

High

880836

TRIP6
Thyroid receptor-interacting protein 6

1

2

High-throughput

0.445

High

880842

ZC3HE
Zinc finger CCCH domain-containing protein 14

1

1

High-throughput

0.445

High

880847

GPAT4
Glycerol-3-phosphate acyltransferase 4

1

1

High-throughput

0.445

High

880848

LMTK2
Serine/threonine-protein kinase LMTK2

1

1

High-throughput

0.445

High

880852

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

1

High-throughput

0.445

High

880861

SFXN2
Sideroflexin-2

1

1

High-throughput

0.445

High

880874

SFXN1
Sideroflexin-1

1

1

High-throughput

0.445

High

880886

VATH
V-type proton ATPase subunit H

1

1

High-throughput

0.445

High

880854

TOM6
Mitochondrial import receptor subunit TOM6 homolog

1

0

Small-scale

0.438

High

506577

GPHRB
Golgi pH regulator B

1

1

High-throughput

0.437

High

131362

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

0

High-throughput

0.426

High

144414

SCD
Stearoyl-CoA desaturase

1

0

High-throughput

0.426

High

168977

QCR8
Cytochrome b-c1 complex subunit 8

1

0

High-throughput

0.426

High

231461

ORC4
Origin recognition complex subunit 4

1

0

High-throughput

0.426

High

302779

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

0

High-throughput

0.426

High

327196

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.426

High

353927

NDUBA
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

1

0

High-throughput

0.426

High

469030

SRPRA
Signal recognition particle receptor subunit alpha

1

0

High-throughput

0.426

High

582145

INGR1
Interferon gamma receptor 1

1

0

High-throughput

0.426

High

724000

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.426

High

880818

PSN1
Presenilin-1

1

0

High-throughput

0.426

High

880819

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

1

0

High-throughput

0.426

High

880821

CAV2
Caveolin-2

1

0

High-throughput

0.426

High

880822

CA2D1
Voltage-dependent calcium channel subunit alpha-2/delta-1

1

0

High-throughput

0.426

High

880826

ACTZ
Alpha-centractin

1

0

High-throughput

0.426

High

880830

IGBP1
Immunoglobulin-binding protein 1

1

0

High-throughput

0.426

High

880832

DSC2
Desmocollin-2

1

0

High-throughput

0.426

High

880833

LBR
Delta(14)-sterol reductase LBR

1

0

High-throughput

0.426

High

880834

OXA1L
Mitochondrial inner membrane protein OXA1L

1

0

High-throughput

0.426

High

880835

NOMO1
BOS complex subunit NOMO1

1

0

High-throughput

0.426

High

880838

TM201
Transmembrane protein 201

1

0

High-throughput

0.426

High

880839

SYRM
Probable arginine--tRNA ligase, mitochondrial

1

0

High-throughput

0.426

High

880840

STEA3
Metalloreductase STEAP3

1

0

High-throughput

0.426

High

880845

NFXL1
NF-X1-type zinc finger protein NFXL1

1

0

High-throughput

0.426

High

880846

LRP10
Low-density lipoprotein receptor-related protein 10

1

0

High-throughput

0.426

High

880849

RDH10
Retinol dehydrogenase 10

1

0

High-throughput

0.426

High

880853

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.426

High

880855

OMA1
Metalloendopeptidase OMA1, mitochondrial

1

0

High-throughput

0.426

High

880856

DAZP1
DAZ-associated protein 1

1

0

High-throughput

0.426

High

880859

GMCL1
Germ cell-less protein-like 1

1

0

High-throughput

0.426

High

880860

S35E1
Solute carrier family 35 member E1

1

0

High-throughput

0.426

High

880864

TM209
Transmembrane protein 209

1

0

High-throughput

0.426

High

880865

CHP1
Calcineurin B homologous protein 1

1

0

High-throughput

0.426

High

880866

TIM29
Mitochondrial import inner membrane translocase subunit Tim29

1

0

High-throughput

0.426

High

880868

TMM43
Transmembrane protein 43

1

0

High-throughput

0.426

High

880869

ELOV1
Very long chain fatty acid elongase 1

1

0

High-throughput

0.426

High

880870

TM39B
Transmembrane protein 39B

1

0

High-throughput

0.426

High

880871

RHBG
Ammonium transporter Rh type B

1

0

High-throughput

0.426

High

880873

TRABD
TraB domain-containing protein

1

0

High-throughput

0.426

High

880876

TM9S3
Transmembrane 9 superfamily member 3

1

0

High-throughput

0.426

High

880878

PLCC
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

1

0

High-throughput

0.426

High

880879

T106B
Transmembrane protein 106B

1

0

High-throughput

0.426

High

880881

CC50A
Cell cycle control protein 50A

1

0

High-throughput

0.426

High

880882

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.426

High

880883

NSMA3
Sphingomyelin phosphodiesterase 4

1

0

High-throughput

0.426

High

880884

DIC
Mitochondrial dicarboxylate carrier

1

0

High-throughput

0.426

High

880885

EI2BD
Translation initiation factor eIF2B subunit delta

1

0

High-throughput

0.426

High

880888

CIA30
Complex I intermediate-associated protein 30, mitochondrial

1

0

High-throughput

0.426

High

880889

C2CD2
C2 domain-containing protein 2

1

0

High-throughput

0.426

High

880890

PEX16
Peroxisomal membrane protein PEX16

1

0

High-throughput

0.426

High

880891

ORNT1
Mitochondrial ornithine transporter 1

1

0

High-throughput

0.426

High

85354

GPHRA
Golgi pH regulator A

1

1

High-throughput

0.407

High

880837

GPAT3
Glycerol-3-phosphate acyltransferase 3

1

1

High-throughput

0.407

High

880844

HACD2
Very-long-chain

1

0

High-throughput

0.279

Low

880857

TV23C
Golgi apparatus membrane protein TVP23 homolog C

1

0

High-throughput

0.279

Low

122601

UBXN8
UBX domain-containing protein 8

1

0

High-throughput

0.232

Low

322380

HAUS5
HAUS augmin-like complex subunit 5

1

0

High-throughput

0.232

Low

350535

CF047
Uncharacterized protein C6orf47

1

0

High-throughput

0.232

Low

880858

ALG14
UDP-N-acetylglucosamine transferase subunit ALG14

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025