Protein: KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

Gene: KAP1, PRKAR1B
Organism: Homo sapiens
Interactions: 158
UniProt ID: P31321

Gene Ontology (top 5):
GO:0004862 - cAMP-dependent protein kinase inhibitor activity
GO:0005771 - multivesicular body
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005952 - cAMP-dependent protein kinase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

498219

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

10

17

Small-scale

0.975

High

568558

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

8

20

Small-scale

0.972

High

610685

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

5

20

High-throughput

0.932

High

679206

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

3

18

High-throughput

0.861

High

609646

KAPCG
cAMP-dependent protein kinase catalytic subunit gamma

2

20

High-throughput

0.811

High

679308

WNK1
Serine/threonine-protein kinase WNK1

2

14

High-throughput

0.793

High

679215

GSK3A
Glycogen synthase kinase-3 alpha

2

6

High-throughput

0.789

High

274183

STK16
Serine/threonine-protein kinase 16

2

6

High-throughput

0.783

High

679218

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

2

4

High-throughput

0.783

High

679277

RPGF5
Rap guanine nucleotide exchange factor 5

2

0

High-throughput

0.770

High

211294

AKA7A
A-kinase anchor protein 7 isoforms alpha and beta

2

8

High-throughput

0.759

High

679320

AKA7G
A-kinase anchor protein 7 isoform gamma

2

8

High-throughput

0.757

High

679216

GSK3B
Glycogen synthase kinase-3 beta

2

6

High-throughput

0.754

High

679205

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

1

17

Small-scale

0.713

High

229925

NUAK1
NUAK family SNF1-like kinase 1

1

6

High-throughput

0.691

High

679232

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

8

High-throughput

0.691

High

310521

VAPB
Vesicle-associated membrane protein-associated protein B/C

3

6

High-throughput

0.667

High

679227

SKP2
S-phase kinase-associated protein 2

2

2

High-throughput

0.628

High

679269

GP161
G-protein coupled receptor 161

2

2

High-throughput

0.628

High

679294

NOX5
NADPH oxidase 5

2

8

High-throughput

0.628

High

679319

VAPA
Vesicle-associated membrane protein-associated protein A

2

6

High-throughput

0.628

High

566299

KPCA
Protein kinase C alpha type

1

11

High-throughput

0.618

High

679231

CUL3
Cullin-3

2

3

High-throughput

0.611

High

679287

AP2M1
AP-2 complex subunit mu

2

1

High-throughput

0.611

High

679300

SYT11
Synaptotagmin-11

2

1

High-throughput

0.611

High

679299

SNAG
Gamma-soluble NSF attachment protein

3

4

High-throughput

0.609

High

338002

EGFR
Epidermal growth factor receptor

2

3

Small-scale

0.608

High

246427

DTNB
Dystrobrevin beta

2

3

High-throughput

0.606

High

297959

FCSD2
F-BAR and double SH3 domains protein 2

2

1

High-throughput

0.606

High

314739

PSMG1
Proteasome assembly chaperone 1

2

1

High-throughput

0.606

High

500392

THA
Thyroid hormone receptor alpha

2

4

High-throughput

0.606

High

679207

KINH
Kinesin-1 heavy chain

2

3

High-throughput

0.606

High

679214

BAG6
Large proline-rich protein BAG6

2

1

High-throughput

0.606

High

679225

ZBT16
Zinc finger and BTB domain-containing protein 16

2

2

High-throughput

0.606

High

679241

QRIC1
Transcriptional regulator QRICH1

2

1

High-throughput

0.606

High

679250

TASO2
Protein TASOR 2

2

1

High-throughput

0.606

High

679258

AKA28
A-kinase anchor protein 14

2

2

High-throughput

0.606

High

679276

SHC3
SHC-transforming protein 3

2

10

High-throughput

0.606

High

679278

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

9

High-throughput

0.606

High

679281

GOGA1
Golgin subfamily A member 1

2

2

High-throughput

0.606

High

679286

SYTL4
Synaptotagmin-like protein 4

2

2

High-throughput

0.606

High

679306

UACA
Uveal autoantigen with coiled-coil domains and ankyrin repeats

2

4

High-throughput

0.606

High

679311

SH24A
SH2 domain-containing protein 4A

2

5

High-throughput

0.606

High

679316

GNL3L
Guanine nucleotide-binding protein-like 3-like protein

2

1

High-throughput

0.606

High

679322

NXF1
Nuclear RNA export factor 1

2

1

High-throughput

0.606

High

679211

ETFB
Electron transfer flavoprotein subunit beta

2

0

High-throughput

0.602

High

679295

ERMAP
Erythroid membrane-associated protein

2

0

High-throughput

0.602

High

679217

PGTB2
Geranylgeranyl transferase type-2 subunit beta

2

0

High-throughput

0.585

High

324250

BAG3
BAG family molecular chaperone regulator 3

2

0

High-throughput

0.580

High

679212

CDN1A
Cyclin-dependent kinase inhibitor 1

2

0

High-throughput

0.580

High

679237

PI5PA
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A

2

0

High-throughput

0.580

High

679238

CDC37
Hsp90 co-chaperone Cdc37

2

0

High-throughput

0.580

High

679272

GA2L2
GAS2-like protein 2

2

0

High-throughput

0.580

High

679288

ZMY19
Zinc finger MYND domain-containing protein 19

2

0

High-throughput

0.580

High

679289

EF2KT
Protein-lysine N-methyltransferase EEF2KMT

2

0

High-throughput

0.580

High

679291

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.580

High

679307

SMG9
Nonsense-mediated mRNA decay factor SMG9

2

0

High-throughput

0.580

High

679324

DACH1
Dachshund homolog 1

2

0

High-throughput

0.580

High

679249

CAMP1
Calmodulin-regulated spectrin-associated protein 1

2

1

High-throughput

0.561

High

530785

RARG
Retinoic acid receptor gamma

2

6

High-throughput

0.553

High

532304

ZNF35
Zinc finger protein 35

2

2

High-throughput

0.553

High

679213

GUC1A
Guanylyl cyclase-activating protein 1

2

1

High-throughput

0.553

High

679226

MTG8
Protein CBFA2T1

2

2

High-throughput

0.553

High

679228

ZN177
Zinc finger protein 177

2

1

High-throughput

0.553

High

679234

VEZF1
Vascular endothelial zinc finger 1

2

3

High-throughput

0.553

High

679251

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

1

High-throughput

0.553

High

679259

IGFN1
Immunoglobulin-like and fibronectin type III domain-containing protein 1

2

3

High-throughput

0.553

High

679260

ZN410
Zinc finger protein 410

2

4

High-throughput

0.553

High

679273

LNX1
E3 ubiquitin-protein ligase LNX

2

5

High-throughput

0.553

High

679305

GLIS2
Zinc finger protein GLIS2

2

4

High-throughput

0.553

High

679312

CBX8
Chromobox protein homolog 8

2

1

High-throughput

0.553

High

679313

DPOE4
DNA polymerase epsilon subunit 4

2

2

High-throughput

0.553

High

679280

AKAP1
A-kinase anchor protein 1, mitochondrial

1

3

Small-scale

0.552

High

257027

DJC13
DnaJ homolog subfamily C member 13

1

2

High-throughput

0.536

High

318930

CEP43
Centrosomal protein 43

1

1

High-throughput

0.536

High

428039

TBB5
Tubulin beta chain

1

3

High-throughput

0.536

High

528402

MYH8
Myosin-8

1

1

High-throughput

0.536

High

679255

PREX2
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein

1

2

High-throughput

0.536

High

679256

FLIP1
Filamin-A-interacting protein 1

1

2

High-throughput

0.536

High

679304

DUS16
Dual specificity protein phosphatase 16

1

1

High-throughput

0.536

High

679318

RAI14
Ankycorbin

1

2

High-throughput

0.536

High

679325

AKA11
A-kinase anchor protein 11

1

5

High-throughput

0.536

High

679245

Q49AR9
ANKS1A protein

1

3

High-throughput

0.515

High

596030

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

1

0

High-throughput

0.513

High

679219

BCAT1
Branched-chain-amino-acid aminotransferase, cytosolic

1

0

High-throughput

0.513

High

679229

PLD1
Phospholipase D1

1

0

High-throughput

0.513

High

679233

AT1A4
Sodium/potassium-transporting ATPase subunit alpha-4

1

0

High-throughput

0.513

High

679239

DOXA2
Dual oxidase maturation factor 2

1

0

High-throughput

0.513

High

679254

ZN746
Zinc finger protein 746

1

0

High-throughput

0.513

High

679264

SULF2
Extracellular sulfatase Sulf-2

1

0

High-throughput

0.513

High

679314

PICK1
PRKCA-binding protein

1

0

High-throughput

0.513

High

475386

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

6

High-throughput

0.501

High

679297

LGMN
Legumain

1

0

High-throughput

0.493

High

201844

ZN749
Zinc finger protein 749

1

1

High-throughput

0.489

High

522594

MYH7
Myosin-7

1

1

High-throughput

0.489

High

679244

TBB8
Tubulin beta-8 chain

1

3

High-throughput

0.489

High

679267

FA43A
Protein FAM43A

1

3

High-throughput

0.489

High

679270

FRMD1
FERM domain-containing protein 1

1

4

High-throughput

0.489

High

679301

AASD1
Alanyl-tRNA editing protein Aarsd1

1

1

High-throughput

0.489

High

679317

KLH28
Kelch-like protein 28

1

1

High-throughput

0.489

High

679279

ANS1A
Ankyrin repeat and SAM domain-containing protein 1A

1

3

High-throughput

0.481

High

162434

XPO1
Exportin-1

1

4

High-throughput

0.479

High

679222

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

4

High-throughput

0.479

High

679310

EGLN3
Prolyl hydroxylase EGLN3

1

3

High-throughput

0.479

High

679292

MY15B
Unconventional myosin-XVB

1

4

High-throughput

0.470

High

679221

CDC42
Cell division control protein 42 homolog

1

4

Small-scale

0.457

High

679223

UBC9
SUMO-conjugating enzyme UBC9

1

5

High-throughput

0.457

High

679315

DISC1
Disrupted in schizophrenia 1 protein

1

1

High-throughput

0.457

High

500731

CLUS
Clusterin

1

0

High-throughput

0.438

High

346039

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.407

High

679252

CRBG3
Very large A-kinase anchor protein

1

1

High-throughput

0.407

High

679271

GG6L2
Golgin subfamily A member 6-like protein 2

1

4

High-throughput

0.407

High

679220

MLF1
Myeloid leukemia factor 1

3

0

High-throughput

0.347

High

679253

SFRP4
Secreted frizzled-related protein 4

3

0

High-throughput

0.347

High

225849

KPRB
Phosphoribosyl pyrophosphate synthase-associated protein 2

2

0

High-throughput

0.328

High

679224

RT15
Small ribosomal subunit protein uS15m

2

0

High-throughput

0.328

High

679248

CF141
Uncharacterized protein C6orf141

2

0

High-throughput

0.328

High

328500

MBD3
Methyl-CpG-binding domain protein 3

2

0

High-throughput

0.316

High

495685

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

2

0

High-throughput

0.316

High

679210

ZNF76
Zinc finger protein 76

2

0

High-throughput

0.316

High

679230

SNW1
SNW domain-containing protein 1

2

0

High-throughput

0.316

High

679236

TEAD4
Transcriptional enhancer factor TEF-3

2

0

High-throughput

0.316

High

679242

F161A
Protein FAM161A

2

0

High-throughput

0.316

High

679243

T10IP
Testis-specific protein 10-interacting protein

2

0

High-throughput

0.316

High

679257

ZN329
Zinc finger protein 329

2

0

High-throughput

0.316

High

679261

F90A1
Protein FAM90A1

2

0

High-throughput

0.316

High

679262

Q8IVT4
Hypothetical MGC50722

2

0

High-throughput

0.316

High

679263

CC103
Coiled-coil domain-containing protein 103

2

0

High-throughput

0.316

High

679266

BD1L2
Biorientation of chromosomes in cell division protein 1-like 2

2

0

High-throughput

0.316

High

679283

GPKOW
G-patch domain and KOW motifs-containing protein

2

0

High-throughput

0.316

High

679284

LMBL2
Lethal(3)malignant brain tumor-like protein 2

2

0

High-throughput

0.316

High

679285

LENG1
Leukocyte receptor cluster member 1

2

0

High-throughput

0.316

High

679290

MED8
Mediator of RNA polymerase II transcription subunit 8

2

0

High-throughput

0.316

High

679293

CEP19
Centrosomal protein of 19 kDa

2

0

High-throughput

0.316

High

679298

PRP18
Pre-mRNA-splicing factor 18

2

0

High-throughput

0.316

High

679323

S30BP
SAP30-binding protein

2

0

High-throughput

0.316

High

254650

ZN623
Zinc finger protein 623

1

0

High-throughput

0.279

Low

276689

GATB
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial

1

0

High-throughput

0.279

Low

528080

BMP1
Bone morphogenetic protein 1

1

0

High-throughput

0.279

Low

533412

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

0

High-throughput

0.279

Low

679208

MCM5
DNA replication licensing factor MCM5

1

0

High-throughput

0.279

Low

679209

TIMP3
Metalloproteinase inhibitor 3

1

0

High-throughput

0.279

Low

679235

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.279

Low

679240

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.279

Low

679246

GREB1
Protein GREB1

1

0

High-throughput

0.279

Low

679247

TFDP3
Transcription factor Dp family member 3

1

0

High-throughput

0.279

Low

679265

IQCF2
IQ domain-containing protein F2

1

0

High-throughput

0.279

Low

679268

CQ078
Uncharacterized protein C17orf78

1

0

High-throughput

0.279

Low

679274

ZN564
Zinc finger protein 564

1

0

High-throughput

0.279

Low

679275

ZN507
Zinc finger protein 507

1

0

High-throughput

0.279

Low

679282

FGF11
Fibroblast growth factor 11

1

0

High-throughput

0.279

Low

679302

CCD32
Coiled-coil domain-containing protein 32

1

0

High-throughput

0.279

Low

679303

TALD3
Protein TALPID3

1

0

High-throughput

0.279

Low

679309

SENP3
Sentrin-specific protease 3

1

0

High-throughput

0.279

Low

679321

MAP10
Microtubule-associated protein 10

1

0

High-throughput

0.279

Low

426580

H10
Histone H1.0

1

0

High-throughput

0.269

Low

679296

DCR1C
Protein artemis

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024