Protein: CKS2
Cyclin-dependent kinases regulatory subunit 2 (CKS-2)

Gene: CKS2
Organism: Homo sapiens
Interactions: 47
UniProt ID: P33552

Gene Ontology (top 5):
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0003682 - chromatin binding
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0007127 - meiosis I
GO:0007346 - regulation of mitotic cell cycle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

414778

CDK1
Cyclin-dependent kinase 1

12

20

Small-scale

0.981

High

625164

CDK2
Cyclin-dependent kinase 2

7

20

Small-scale

0.969

High

706796

CDK3
Cyclin-dependent kinase 3

5

20

High-throughput

0.926

High

706809

PMYT1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

4

7

High-throughput

0.813

High

706792

CKS1
Cyclin-dependent kinases regulatory subunit 1

2

5

High-throughput

0.811

High

538483

CCNB1
G2/mitotic-specific cyclin-B1

6

20

Small-scale

0.735

High

706805

KCC1D
Calcium/calmodulin-dependent protein kinase type 1D

3

0

High-throughput

0.720

High

590135

CCNA2
Cyclin-A2

5

20

Small-scale

0.714

High

303832

CCNB2
G2/mitotic-specific cyclin-B2

3

20

Small-scale

0.670

High

706818

FZR1
Fizzy-related protein homolog

3

6

High-throughput

0.667

High

267131

GEMI
Geminin

2

1

High-throughput

0.628

High

624551

CCNE1
G1/S-specific cyclin-E1

2

20

High-throughput

0.628

High

706790

CDN1B
Cyclin-dependent kinase inhibitor 1B

2

3

High-throughput

0.628

High

706813

CDT1
DNA replication factor Cdt1

2

1

High-throughput

0.628

High

706815

IKZF5
Zinc finger protein Pegasus

2

3

High-throughput

0.628

High

706791

CDK9
Cyclin-dependent kinase 9

1

16

High-throughput

0.618

High

706797

CDK5
Cyclin-dependent kinase 5

1

20

High-throughput

0.618

High

706817

CDK12
Cyclin-dependent kinase 12

1

16

High-throughput

0.618

High

706788

CDN1A
Cyclin-dependent kinase inhibitor 1

2

3

High-throughput

0.611

High

706787

CKS2
Cyclin-dependent kinases regulatory subunit 2

1

5

Small-scale

0.575

High

706794

EF1A1
Elongation factor 1-alpha 1

1

2

High-throughput

0.541

High

63998

SPDE4
Speedy protein E4

1

5

High-throughput

0.536

High

610198

CCNO
Cyclin-O

1

20

High-throughput

0.536

High

706800

CDC20
Cell division cycle protein 20 homolog

1

6

High-throughput

0.536

High

706804

SPDYC
Speedy protein C

1

5

High-throughput

0.536

High

706793

GRB2
Growth factor receptor-bound protein 2

1

0

High-throughput

0.518

High

706810

NPAS1
Neuronal PAS domain-containing protein 1

1

0

High-throughput

0.513

High

706795

CCNA1
Cyclin-A1

1

20

Small-scale

0.501

High

706799

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

1

Small-scale

0.501

High

706802

CDC37
Hsp90 co-chaperone Cdc37

1

1

Small-scale

0.501

High

706816

PKHG2
Pleckstrin homology domain-containing family G member 2

1

1

High-throughput

0.489

High

706798

KMT2A
Histone-lysine N-methyltransferase 2A

1

1

Small-scale

0.479

High

386190

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

421972

LDHB
L-lactate dehydrogenase B chain

1

1

Small-scale

0.457

High

431578

HS90A
Heat shock protein HSP 90-alpha

1

3

Small-scale

0.457

High

706803

SPDE7
Putative speedy protein E7

1

5

High-throughput

0.445

High

706806

LACC1
Purine nucleoside phosphorylase LACC1

3

0

High-throughput

0.347

High

706808

GA2L1
GAS2-like protein 1

2

0

High-throughput

0.328

High

373000

VTNC
Vitronectin

1

0

High-throughput

0.282

High

706801

U119A
Protein unc-119 homolog A

1

0

High-throughput

0.282

High

706819

T22D4
TSC22 domain family protein 4

1

0

High-throughput

0.282

High

706807

PTGR3
Prostaglandin reductase 3

1

0

High-throughput

0.279

Low

706811

DHRS6
Dehydrogenase/reductase SDR family member 6

1

0

High-throughput

0.279

Low

706812

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.279

Low

706814

GO45
Golgin-45

1

0

High-throughput

0.265

Low

706789

PERI
Peripherin

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024