Protein: KLK3
Prostate-specific antigen (PSA) (EC 3.4.21.77) (Gamma-seminoprotein) (Seminin) (Kallikrein-3) (P-30 antigen) (Semenogelase)

Gene: KLK3
Organism: Homo sapiens
Interactions: 55
UniProt ID: P07288

Gene Ontology (top 5):
GO:0002803 - positive regulation of antibacterial peptide production
GO:0003073 - regulation of systemic arterial blood pressure
GO:0004175 - endopeptidase activity
GO:0004252 - serine-type endopeptidase activity
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

397629

IPSP
Plasma serine protease inhibitor

2

19

Small-scale

0.811

High

426505

ANDR
Androgen receptor

7

9

Small-scale

0.738

High

270253

LRP6
Low-density lipoprotein receptor-related protein 6

1

16

High-throughput

0.691

High

426510

PRTN3
Myeloblastin

1

15

High-throughput

0.691

High

258288

LRP5
Low-density lipoprotein receptor-related protein 5

1

15

High-throughput

0.618

High

344149

A1AT
Alpha-1-antitrypsin

1

20

Small-scale

0.618

High

344409

A2MG
Alpha-2-macroglobulin

1

10

Small-scale

0.618

High

426511

ZA2G
Zinc-alpha-2-glycoprotein

1

6

High-throughput

0.618

High

69227

MI4GD
MIF4G domain-containing protein

3

2

High-throughput

0.609

High

426517

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

2

3

High-throughput

0.601

High

353615

IGHG1
Immunoglobulin heavy constant gamma 1

1

9

High-throughput

0.575

High

426506

BIP
Endoplasmic reticulum chaperone BiP

2

10

High-throughput

0.571

High

158726

HAT1
Histone acetyltransferase type B catalytic subunit

1

1

High-throughput

0.536

High

305207

NXPH2
Neurexophilin-2

1

2

High-throughput

0.536

High

363690

ALBU
Albumin

1

7

High-throughput

0.536

High

426509

FGFR3
Fibroblast growth factor receptor 3

1

11

High-throughput

0.536

High

426513

GRN
Progranulin

1

1

High-throughput

0.536

High

426516

ANAG
Alpha-N-acetylglucosaminidase

1

2

High-throughput

0.536

High

426525

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

1

5

High-throughput

0.536

High

426531

VWDE
von Willebrand factor D and EGF domain-containing protein

1

11

High-throughput

0.536

High

426532

CHSTE
Carbohydrate sulfotransferase 14

1

3

High-throughput

0.536

High

426535

I17RA
Interleukin-17 receptor A

1

4

High-throughput

0.536

High

426537

DIDO1
Death-inducer obliterator 1

1

3

High-throughput

0.536

High

426539

TX101
Testis-expressed protein 101

1

1

High-throughput

0.536

High

426544

ADA21
Disintegrin and metalloproteinase domain-containing protein 21

1

17

High-throughput

0.536

High

426545

ATS7
A disintegrin and metalloproteinase with thrombospondin motifs 7

1

13

High-throughput

0.536

High

201511

DHH
Desert hedgehog protein

1

0

High-throughput

0.513

High

426528

ZN550
Zinc finger protein 550

1

0

High-throughput

0.513

High

426542

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.513

High

426515

PLXA3
Plexin-A3

1

16

High-throughput

0.489

High

426520

ITA7
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]

1

9

High-throughput

0.489

High

426523

FUT11
Alpha-(1,3)-fucosyltransferase 11

1

2

High-throughput

0.489

High

426529

FRAS1
Extracellular matrix organizing protein FRAS1

1

20

High-throughput

0.489

High

426538

EDEM2
ER degradation-enhancing alpha-mannosidase-like protein 2

1

9

High-throughput

0.489

High

426541

SEM6B
Semaphorin-6B

1

10

High-throughput

0.489

High

426543

SEM4G
Semaphorin-4G

1

12

High-throughput

0.489

High

380974

SEMG1
Semenogelin-1

1

2

High-throughput

0.479

High

426507

PPAP
Prostatic acid phosphatase

1

3

High-throughput

0.479

High

426508

H15
Histone H1.5

1

4

Small-scale

0.479

High

426518

SEMG2
Semenogelin-2

1

2

High-throughput

0.479

High

426519

REL
Proto-oncogene c-Rel

1

3

Small-scale

0.479

High

426524

DCAF6
DDB1- and CUL4-associated factor 6

1

3

High-throughput

0.479

High

426527

MYSM1
Deubiquitinase MYSM1

1

3

Small-scale

0.479

High

426533

KAT2B
Histone acetyltransferase KAT2B

1

2

Small-scale

0.479

High

426504

MSMB
Beta-microseminoprotein

1

0

High-throughput

0.458

High

426514

CTNB1
Catenin beta-1

1

0

Small-scale

0.458

High

426521

H31T
Histone H3.1t

1

0

Small-scale

0.458

High

426522

H2A2C
Histone H2A type 2-C

1

0

Small-scale

0.458

High

426536

ERP44
Endoplasmic reticulum resident protein 44

1

8

High-throughput

0.445

High

426534

SEH1
Nucleoporin SEH1

1

3

High-throughput

0.437

High

426546

GRIP1
Glutamate receptor-interacting protein 1

1

1

Small-scale

0.437

High

426512

DCK
Deoxycytidine kinase

1

0

High-throughput

0.279

Low

426526

TMM69
Transmembrane protein 69

1

0

High-throughput

0.279

Low

426530

CA174
UPF0688 protein C1orf174

1

0

High-throughput

0.279

Low

426540

ITPA
Inosine triphosphate pyrophosphatase

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024