Protein: CWC15
Spliceosome-associated protein CWC15 homolog

Gene: CWC15
Organism: Homo sapiens
Interactions: 93
UniProt ID: Q9P013

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1111324

SNW1
SNW domain-containing protein 1

4

0

High-throughput

0.840

High

1361536

CTBL1
Beta-catenin-like protein 1

6

2

Small-scale

0.746

High

222539

PLRG1
Pleiotropic regulator 1

2

1

Small-scale

0.737

High

1453665

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

1

High-throughput

0.691

High

1404468

CDC5L
Cell division cycle 5-like protein

4

2

Small-scale

0.691

High

1388757

SIR1
NAD-dependent protein deacetylase sirtuin-1

3

1

High-throughput

0.667

High

1451920

SIR5
NAD-dependent protein deacylase sirtuin-5, mitochondrial

3

1

High-throughput

0.667

High

1453664

PRP19
Pre-mRNA-processing factor 19

3

2

Small-scale

0.662

High

1453666

PPIL1
Peptidyl-prolyl cis-trans isomerase-like 1

1

0

High-throughput

0.656

High

986779

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

1

High-throughput

0.618

High

1387607

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

2

High-throughput

0.618

High

1182869

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

2

1

High-throughput

0.602

High

1450688

DJC17
DnaJ homolog subfamily C member 17

2

0

High-throughput

0.595

High

298106

SPF27
Pre-mRNA-splicing factor SPF27

2

0

Small-scale

0.576

High

1227598

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.553

High

471293

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.536

High

485750

RU2A
U2 small nuclear ribonucleoprotein A'

1

2

High-throughput

0.536

High

807603

IF4A3
Eukaryotic initiation factor 4A-III

1

1

High-throughput

0.536

High

1023035

FGD1
FYVE, RhoGEF and PH domain-containing protein 1

2

1

High-throughput

0.521

High

1309678

ARHGJ
Rho guanine nucleotide exchange factor 19

2

1

High-throughput

0.521

High

286096

SF3B1
Splicing factor 3B subunit 1

1

0

High-throughput

0.513

High

351362

SYF2
Pre-mRNA-splicing factor SYF2

1

0

High-throughput

0.513

High

478236

SNRPA
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.513

High

480333

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

542256

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

574495

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

0

High-throughput

0.513

High

788243

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.513

High

941587

CTBP2
C-terminal-binding protein 2

1

0

High-throughput

0.513

High

973833

RUXE
Small nuclear ribonucleoprotein E

1

0

High-throughput

0.513

High

1051975

KPCD
Protein kinase C delta type

1

0

High-throughput

0.513

High

1057009

FMR1
Fragile X messenger ribonucleoprotein 1

1

0

High-throughput

0.513

High

1114497

CUL3
Cullin-3

1

0

High-throughput

0.513

High

1127209

RBM39
RNA-binding protein 39

1

0

High-throughput

0.513

High

1149210

SF3A1
Splicing factor 3A subunit 1

1

0

High-throughput

0.513

High

1160328

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

0

High-throughput

0.513

High

1163711

PCKGM
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial

1

0

High-throughput

0.513

High

1356578

CCD12
Coiled-coil domain-containing protein 12

1

0

High-throughput

0.513

High

1410079

USB1
U6 snRNA phosphodiesterase 1

1

0

High-throughput

0.513

High

1453663

ISY1
Pre-mRNA-splicing factor ISY1 homolog

1

0

High-throughput

0.513

High

1453667

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

1

0

High-throughput

0.513

High

1394016

SPF45
Splicing factor 45

1

1

High-throughput

0.508

High

1209742

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.501

High

1367450

ESR2
Estrogen receptor beta

1

1

High-throughput

0.484

High

316090

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

373349

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

404489

GCR
Glucocorticoid receptor

1

1

High-throughput

0.479

High

406742

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

1155840

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.479

High

1451076

RBM22
Pre-mRNA-splicing factor RBM22

1

1

High-throughput

0.479

High

302653

RNF8
E3 ubiquitin-protein ligase RNF8

1

0

Small-scale

0.458

High

401610

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

766909

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

879555

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

961113

MGN
Protein mago nashi homolog

1

0

High-throughput

0.458

High

980454

H4
Histone H4

1

0

High-throughput

0.458

High

998887

H31
Histone H3.1

1

0

High-throughput

0.458

High

1024895

VIGLN
Vigilin

1

0

High-throughput

0.458

High

1026569

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.458

High

1033278

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

1094642

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

0

High-throughput

0.458

High

1128131

DHX8
ATP-dependent RNA helicase DHX8

1

0

High-throughput

0.458

High

1137555

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

1148663

SF3A2
Splicing factor 3A subunit 2

1

0

High-throughput

0.458

High

1156882

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

1235550

IFIX
Pyrin and HIN domain-containing protein 1

1

0

High-throughput

0.458

High

1289671

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1290782

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.458

High

1313486

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1338406

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

1346962

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.458

High

1414604

DDX23
Probable ATP-dependent RNA helicase DDX23

1

0

High-throughput

0.458

High

1447370

ANLN
Anillin

1

0

High-throughput

0.458

High

1452445

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1453662

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

348217

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

1

High-throughput

0.437

High

430444

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

538031

HSP7C
Heat shock cognate 71 kDa protein

1

0

Small-scale

0.426

High

1314456

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.426

High

220135

SGCE
Epsilon-sarcoglycan

1

0

High-throughput

0.282

High

881746

FNTB
Protein farnesyltransferase subunit beta

1

0

High-throughput

0.279

Low

1417806

ANGL4
Angiopoietin-related protein 4

1

0

High-throughput

0.279

Low

1436871

ARMT1
Damage-control phosphatase ARMT1

1

0

High-throughput

0.279

Low

106764

APRIO
Alternative prion protein

1

0

Small-scale

0.261

Low

404936

PRIO
Major prion protein

1

0

Small-scale

0.261

Low

423348

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.261

Low

608369

EGLN
Endoglin

1

0

High-throughput

0.261

Low

157938

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

940323

SYMC
Methionine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.249

Low

953717

RAC3
Ras-related C3 botulinum toxin substrate 3

1

0

High-throughput

0.249

Low

995861

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.249

Low

1060723

SOS2
Son of sevenless homolog 2

1

0

High-throughput

0.249

Low

1253000

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.249

Low

255251

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025