Protein: PAX8
Paired box protein Pax-8

Gene: PAX8
Organism: Homo sapiens
Interactions: 113
UniProt ID: Q06710

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

988754

TLE5
TLE family member 5

3

20

High-throughput

0.653

High

988755

EP300
Histone acetyltransferase p300

2

20

Small-scale

0.606

High

257464

CREST
Calcium-responsive transactivator

2

16

High-throughput

0.606

High

270982

GCM2
Chorion-specific transcription factor GCMb

2

1

High-throughput

0.606

High

678904

HXC8
Homeobox protein Hox-C8

2

20

High-throughput

0.606

High

678996

HXC9
Homeobox protein Hox-C9

2

20

High-throughput

0.606

High

960084

CDK3
Cyclin-dependent kinase 3

2

5

High-throughput

0.606

High

988815

SAE1
SUMO-activating enzyme subunit 1

2

2

High-throughput

0.606

High

160529

AURKA
Aurora kinase A

1

3

Small-scale

0.578

High

443175

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.561

High

799089

NKX21
Homeobox protein Nkx-2.1

1

18

Small-scale

0.561

High

988759

SKP2
S-phase kinase-associated protein 2

1

7

Small-scale

0.561

High

988763

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.561

High

988767

LONF1
LON peptidase N-terminal domain and RING finger protein 1

2

8

High-throughput

0.553

High

167529

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

4

High-throughput

0.541

High

988766

OBF1
POU domain class 2-associating factor 1

1

1

High-throughput

0.541

High

589182

ANXA7
Annexin A7

1

0

High-throughput

0.537

High

971654

PAX5
Paired box protein Pax-5

1

11

High-throughput

0.536

High

537883

KPYM
Pyruvate kinase PKM

1

0

High-throughput

0.518

High

135110

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.515

High

414257

RB
Retinoblastoma-associated protein

1

5

Small-scale

0.515

High

973845

PAX2
Paired box protein Pax-2

1

10

High-throughput

0.515

High

988756

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.515

High

727508

HNF1B
Hepatocyte nuclear factor 1-beta

1

16

High-throughput

0.501

High

988799

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

4

High-throughput

0.500

High

131717

BCL9
B-cell CLL/lymphoma 9 protein

1

20

High-throughput

0.479

High

146202

ARI1A
AT-rich interactive domain-containing protein 1A

1

20

High-throughput

0.479

High

152634

KMT2D
Histone-lysine N-methyltransferase 2D

1

20

High-throughput

0.479

High

164218

ZN609
Zinc finger protein 609

1

20

High-throughput

0.479

High

183108

KDM6A
Lysine-specific demethylase 6A

1

8

High-throughput

0.479

High

231229

ZEB2
Zinc finger E-box-binding homeobox 2

1

8

High-throughput

0.479

High

261479

NCOR1
Nuclear receptor corepressor 1

1

20

High-throughput

0.479

High

473502

ATX1L
Ataxin-1-like

1

10

High-throughput

0.479

High

550373

ZEP1
Zinc finger protein 40

1

10

High-throughput

0.479

High

567834

HXB9
Homeobox protein Hox-B9

1

20

High-throughput

0.479

High

582246

NUCL
Nucleolin

1

1

High-throughput

0.479

High

782526

HNF4A
Hepatocyte nuclear factor 4-alpha

1

8

Small-scale

0.479

High

823922

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

20

High-throughput

0.479

High

837763

MNX1
Motor neuron and pancreas homeobox protein 1

1

20

High-throughput

0.479

High

846757

SMCA2
Probable global transcription activator SNF2L2

1

16

High-throughput

0.479

High

868449

ATX1
Ataxin-1

1

10

High-throughput

0.479

High

902887

DCAF7
DDB1- and CUL4-associated factor 7

1

5

High-throughput

0.479

High

980588

TLE1
Transducin-like enhancer protein 1

1

20

High-throughput

0.479

High

980733

TLE3
Transducin-like enhancer protein 3

1

20

High-throughput

0.479

High

980927

TLE4
Transducin-like enhancer protein 4

1

20

High-throughput

0.479

High

988758

GPS2
G protein pathway suppressor 2

1

4

High-throughput

0.479

High

988762

MEF2D
Myocyte-specific enhancer factor 2D

1

3

High-throughput

0.479

High

988764

RBBP5
Retinoblastoma-binding protein 5

1

4

High-throughput

0.479

High

988765

NCOA2
Nuclear receptor coactivator 2

1

15

High-throughput

0.479

High

988771

NIPBL
Nipped-B-like protein

1

12

High-throughput

0.479

High

988773

MDEAS
Mitotic deacetylase-associated SANT domain protein

1

7

High-throughput

0.479

High

988774

BCOR
BCL-6 corepressor

1

7

High-throughput

0.479

High

988775

PAXI1
PAX-interacting protein 1

1

20

High-throughput

0.479

High

988776

PCGF5
Polycomb group RING finger protein 5

1

18

High-throughput

0.479

High

988777

LDB1
LIM domain-binding protein 1

1

7

High-throughput

0.479

High

988778

PB1
Protein polybromo-1

1

12

High-throughput

0.479

High

988779

ZFHX4
Zinc finger homeobox protein 4

1

14

High-throughput

0.479

High

988781

I2BP1
Interferon regulatory factor 2-binding protein 1

1

2

High-throughput

0.479

High

988782

FOXP4
Forkhead box protein P4

1

20

High-throughput

0.479

High

988783

KMT2C
Histone-lysine N-methyltransferase 2C

1

20

High-throughput

0.479

High

988784

ARI1B
AT-rich interactive domain-containing protein 1B

1

20

High-throughput

0.479

High

988785

KDM2B
Lysine-specific demethylase 2B

1

7

High-throughput

0.479

High

988786

MORC4
MORC family CW-type zinc finger protein 4

1

5

High-throughput

0.479

High

988788

BCL7C
B-cell CLL/lymphoma 7 protein family member C

1

6

High-throughput

0.479

High

988789

MAML1
Mastermind-like protein 1

1

20

High-throughput

0.479

High

988790

DPF1
Zinc finger protein neuro-d4

1

20

High-throughput

0.479

High

988791

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.479

High

988792

CBP
CREB-binding protein

1

20

High-throughput

0.479

High

988793

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

14

High-throughput

0.479

High

988795

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

9

High-throughput

0.479

High

988796

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

988797

PYGO2
Pygopus homolog 2

1

2

High-throughput

0.479

High

988798

PCGF1
Polycomb group RING finger protein 1

1

13

High-throughput

0.479

High

988800

SSBP3
Single-stranded DNA-binding protein 3

1

11

High-throughput

0.479

High

988802

MKRN2
E3 ubiquitin-protein ligase makorin-2

1

2

Small-scale

0.479

High

988803

TDIF1
Deoxynucleotidyltransferase terminal-interacting protein 1

1

4

High-throughput

0.479

High

988804

NKX24
Homeobox protein Nkx-2.4

1

20

High-throughput

0.479

High

988805

FOXP1
Forkhead box protein P1

1

20

High-throughput

0.479

High

988807

ZN644
Zinc finger protein 644

1

10

High-throughput

0.479

High

988808

ZN703
Zinc finger protein 703

1

18

High-throughput

0.479

High

988810

HM20A
High mobility group protein 20A

1

20

High-throughput

0.479

High

988813

HM20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

1

20

High-throughput

0.479

High

988814

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

11

High-throughput

0.479

High

988816

TRPS1
Zinc finger transcription factor Trps1

1

13

High-throughput

0.479

High

988818

ZN608
Zinc finger protein 608

1

12

High-throughput

0.479

High

988819

PRR12
Proline-rich protein 12

1

20

High-throughput

0.479

High

988820

SATB2
DNA-binding protein SATB2

1

9

High-throughput

0.479

High

988821

NCOR2
Nuclear receptor corepressor 2

1

20

High-throughput

0.479

High

988822

NCOA3
Nuclear receptor coactivator 3

1

15

High-throughput

0.479

High

302389

CSTN1
Calsyntenin-1

1

0

High-throughput

0.458

High

455355

PARP1
Poly [ADP-ribose] polymerase 1

1

0

Small-scale

0.458

High

988757

ILF2
Interleukin enhancer-binding factor 2

1

0

Small-scale

0.458

High

988770

RSBN1
Lysine-specific demethylase 9

1

0

High-throughput

0.458

High

988772

TET2
Methylcytosine dioxygenase TET2

1

0

High-throughput

0.458

High

988794

TMA16
Translation machinery-associated protein 16

1

0

High-throughput

0.458

High

988812

LYAR
Cell growth-regulating nucleolar protein

1

0

Small-scale

0.458

High

988817

FBX3
F-box only protein 3

1

0

Small-scale

0.458

High

988760

SMAD4
Mothers against decapentaplegic homolog 4

1

6

High-throughput

0.457

High

148713

CTRO
Citron Rho-interacting kinase

1

3

High-throughput

0.457

High

988761

GSE1
Genetic suppressor element 1

1

4

High-throughput

0.437

High

988768

QSER1
Glutamine and serine-rich protein 1

1

20

High-throughput

0.437

High

988769

PRC2B
Protein PRRC2B

1

18

High-throughput

0.437

High

988780

PRSR1
Proline and serine-rich protein 1

1

20

High-throughput

0.437

High

988801

UNK
RING finger protein unkempt homolog

1

3

High-throughput

0.437

High

988806

CPVL
Probable serine carboxypeptidase CPVL

1

1

High-throughput

0.437

High

988809

FBSL
Fibrosin-1-like protein

1

8

High-throughput

0.437

High

988787

DOK4
Docking protein 4

2

0

High-throughput

0.316

High

988811

SERC1
Serine incorporator 1

1

0

High-throughput

0.301

High

988753

CXCL9
C-X-C motif chemokine 9

1

0

High-throughput

0.282

High

279528

FLOT1
Flotillin-1

1

0

High-throughput

0.261

Low

519176

KCRB
Creatine kinase B-type

1

0

High-throughput

0.261

Low

787722

HUTH
Histidine ammonia-lyase

1

0

High-throughput

0.261

Low

400530

RLA2
Large ribosomal subunit protein P2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024