Protein: SP382
Pre-mRNA-splicing factor SPP382 (CLF1 complex factor 8) (Nineteen complex-related protein 1) (NTC-related protein 1) (Suppressor of PRP38 protein 2)

Gene: SP382, SPP382
Organism: Saccharomyces cerevisiae S288C
Interactions: 159
UniProt ID: Q06411

Gene Ontology (top 5):
GO:0000349 - generation of catalytic spliceosome for first transesterification step
GO:0000390 - spliceosomal complex disassembly
GO:0000781 - chromosome, telomeric region
GO:0003676 - nucleic acid binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

859436

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

14

0

Small-scale

0.936

High

697265

BRR2
Pre-mRNA-splicing helicase BRR2

3

0

High-throughput

0.816

High

856941

CWC23
Pre-mRNA-splicing factor CWC23

10

0

Small-scale

0.726

High

733097

NTR2
Pre-mRNA-splicing factor NTR2

9

0

Small-scale

0.726

High

987205

CLF1
Pre-mRNA-splicing factor CLF1

4

3

Small-scale

0.699

High

704721

PRP8
Pre-mRNA-splicing factor 8

4

0

Small-scale

0.667

High

859694

LIF1
Ligase-interacting factor 1

4

0

Small-scale

0.659

High

766962

RSMB
Small nuclear ribonucleoprotein-associated protein B

3

0

High-throughput

0.638

High

873669

RUXF
Small nuclear ribonucleoprotein F

3

0

High-throughput

0.629

High

978480

SYF1
Pre-mRNA-splicing factor SYF1

2

3

Small-scale

0.628

High

657771

YJU2
Splicing factor YJU2

3

0

Small-scale

0.623

High

987189

SWC7
SWR1-complex protein 7

3

0

High-throughput

0.612

High

977080

CEF1
Pre-mRNA-splicing factor CEF1

2

0

Small-scale

0.606

High

731775

SN114
Pre-mRNA-splicing factor SNU114

2

0

High-throughput

0.602

High

987208

PRP46
Pre-mRNA-splicing factor PRP46

2

0

High-throughput

0.602

High

655758

PRP45
Pre-mRNA-processing protein 45

2

0

Small-scale

0.596

High

987187

YL419
Putative ATP-dependent RNA helicase YLR419W

1

1

High-throughput

0.590

High

641141

DAL80
Nitrogen regulatory protein DAL80

2

1

High-throughput

0.590

High

792457

GZF3
Protein GZF3

2

1

High-throughput

0.590

High

568418

RTPT
Small ribosomal subunit protein mS26

2

0

High-throughput

0.582

High

860963

DAM1
DASH complex subunit DAM1

2

0

High-throughput

0.582

High

598651

ISY1
Pre-mRNA-splicing factor ISY1

2

0

Small-scale

0.576

High

692361

PRP19
Pre-mRNA-processing factor 19

2

0

Small-scale

0.576

High

761152

PCF11
Protein PCF11

2

0

High-throughput

0.565

High

987185

SP382
Pre-mRNA-splicing factor SPP382

2

0

Small-scale

0.565

High

770339

RUXG
Small nuclear ribonucleoprotein G

2

0

High-throughput

0.563

High

638865

SPB4
ATP-dependent rRNA helicase SPB4

1

0

High-throughput

0.560

High

987196

ULS1
ATP-dependent helicase ULS1

1

0

High-throughput

0.560

High

860104

SWC4
SWR1-complex protein 4

2

0

High-throughput

0.551

High

865567

SQS1
Protein SQS1

2

0

Small-scale

0.551

High

987206

IES3
Ino eighty subunit 3

2

0

High-throughput

0.541

High

492522

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.536

High

512830

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.536

High

969005

SKO1
CRE-binding bZIP protein SKO1

1

0

High-throughput

0.518

High

978106

CTK1
CTD kinase subunit alpha

1

0

High-throughput

0.518

High

987190

BRE1
E3 ubiquitin-protein ligase BRE1

1

0

High-throughput

0.518

High

499086

RL4A
Large ribosomal subunit protein uL4A

1

0

Small-scale

0.513

High

746881

SLT11
Pre-mRNA-splicing factor SLT11

1

0

High-throughput

0.513

High

795425

SMD3
Small nuclear ribonucleoprotein Sm D3

1

0

High-throughput

0.513

High

810168

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.513

High

861077

SYF2
Pre-mRNA-splicing factor SYF2

1

0

Small-scale

0.513

High

982879

RRP5
rRNA biogenesis protein RRP5

1

0

Small-scale

0.513

High

987197

SNX3
Sorting nexin-3

1

1

Small-scale

0.494

High

987199

RKM1
Ribosomal lysine N-methyltransferase 1

1

0

High-throughput

0.493

High

655003

ERV1
Mitochondrial FAD-linked sulfhydryl oxidase ERV1

1

0

High-throughput

0.486

High

861189

BTN2
Protein BTN2

1

0

High-throughput

0.486

High

970405

ADA2
Transcriptional adapter 2

1

0

High-throughput

0.486

High

987165

ATG17
Autophagy-related protein 17

1

0

High-throughput

0.486

High

370990

REP2
Partitioning protein REP2

1

0

Small-scale

0.479

High

700802

SMC1
Structural maintenance of chromosomes protein 1

1

0

High-throughput

0.460

High

743227

CDC27
Anaphase-promoting complex subunit CDC27

1

0

High-throughput

0.460

High

935998

HSK3
DASH complex subunit HSK3

1

0

High-throughput

0.460

High

972071

CENPP
Inner kinetochore subunit CTF19

1

0

High-throughput

0.460

High

986190

NEJ1
Non-homologous end-joining protein 1

1

0

Small-scale

0.460

High

987193

SDO1
Ribosome maturation protein SDO1

1

0

Small-scale

0.460

High

663391

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

987198

NCBP2
Nuclear cap-binding protein subunit 2

1

0

High-throughput

0.458

High

987200

RU2A
U2 small nuclear ribonucleoprotein A'

1

0

High-throughput

0.458

High

987203

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

514591

BIK1
Nuclear fusion protein BIK1

1

1

High-throughput

0.457

High

586444

PRP6
Pre-mRNA-splicing factor 6

1

3

High-throughput

0.457

High

706063

NIP80
Protein NIP100

1

1

High-throughput

0.457

High

752420

STB5
Protein STB5

1

1

High-throughput

0.457

High

817354

ASK10
Activator of SKN7 protein 10

1

1

High-throughput

0.457

High

981850

SNO4
Probable glutathione-independent glyoxalase SNO4

1

1

High-throughput

0.457

High

985923

RGC1
Regulator of the glycerol channel 1

1

1

High-throughput

0.457

High

987201

HSP32
Probable glutathione-independent glyoxalase HSP32

1

1

High-throughput

0.457

High

495031

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

695588

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

696074

HSP79
Heat shock protein homolog SSE2

1

3

High-throughput

0.445

High

769545

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

830682

NU145
Nucleoporin NUP145

1

1

High-throughput

0.445

High

520679

REV1
DNA repair protein REV1

1

0

High-throughput

0.438

High

585877

RDS2
Regulator of drug sensitivity 2

1

0

High-throughput

0.438

High

606223

TRX1
Thioredoxin-1

1

0

High-throughput

0.438

High

631050

SSK22
Serine/threonine-protein kinase SSK22

1

0

High-throughput

0.438

High

635928

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

0

High-throughput

0.438

High

636082

CSM1
Monopolin complex subunit CSM1

1

0

High-throughput

0.438

High

636182

NOT1
General negative regulator of transcription subunit 1

1

0

High-throughput

0.438

High

650396

SPT5
Transcription elongation factor SPT5

1

0

High-throughput

0.438

High

681334

TPS2
Trehalose-phosphatase

1

0

High-throughput

0.438

High

688671

MCM10
Minichromosome maintenance protein 10

1

0

High-throughput

0.438

High

691180

MEI5
Meiosis protein 5

1

0

High-throughput

0.438

High

697877

YBB0
Uncharacterized protein YBL010C

1

0

High-throughput

0.438

High

698574

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

0

High-throughput

0.438

High

700218

RT04
Small ribosomal subunit protein uS2m

1

0

High-throughput

0.438

High

703275

PRP40
Pre-mRNA-processing protein PRP40

1

0

High-throughput

0.438

High

715562

TOM20
Mitochondrial import receptor subunit TOM20

1

0

High-throughput

0.438

High

743696

HMT1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.438

High

747681

YBY8
Uncharacterized protein YBR138C

1

0

High-throughput

0.438

High

748578

RMD9L
RNA-binding protein RMD9-like, mitochondrial

1

0

High-throughput

0.438

High

754038

PIH1
Protein interacting with Hsp90 1

1

0

High-throughput

0.438

High

754261

RSC30
Chromatin structure-remodeling complex protein RSC30

1

0

High-throughput

0.438

High

755671

BZZ1
Protein BZZ1

1

0

High-throughput

0.438

High

762770

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

1

0

High-throughput

0.438

High

763227

MBP1
Transcription factor MBP1

1

0

High-throughput

0.438

High

763956

MTW1
Kinetochore-associated protein MTW1

1

0

High-throughput

0.438

High

765922

HPA3
D-amino-acid N-acetyltransferase HPA3

1

0

High-throughput

0.438

High

766826

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.438

High

768120

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

1

0

High-throughput

0.438

High

769952

WRIP1
DNA-dependent ATPase MGS1

1

0

High-throughput

0.438

High

772341

ATAD2
ATPase histone chaperone YTA7

1

0

High-throughput

0.438

High

774001

MLP2
Protein MLP2

1

0

High-throughput

0.438

High

774821

AIR1
Protein AIR1

1

0

High-throughput

0.438

High

774910

CSN11
Cop9 signalosome complex subunit 11

1

0

High-throughput

0.438

High

775869

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.438

High

797194

EPL1
Enhancer of polycomb-like protein 1

1

0

High-throughput

0.438

High

805191

SUM1
Suppressor of mar1-1 protein

1

0

High-throughput

0.438

High

810734

NET1
Nucleolar protein NET1

1

0

High-throughput

0.438

High

811870

YJ26
Uncharacterized protein YJR056C

1

0

High-throughput

0.438

High

817368

HGH1
Protein HGH1

1

0

High-throughput

0.438

High

860009

PIB2
Glutamine sensor PIB2

1

0

High-throughput

0.438

High

861608

PXR1
Protein PXR1

1

0

High-throughput

0.438

High

862518

RRN9
RNA polymerase I-specific transcription initiation factor RRN9

1

0

High-throughput

0.438

High

866361

NST1
Stress response protein NST1

1

0

High-throughput

0.438

High

972702

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.438

High

976050

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

1

0

High-throughput

0.438

High

976426

EBS1
Nonsense-mediated mRNA decay factor EBS1

1

0

High-throughput

0.438

High

976825

TMA23
Protein TMA23

1

0

High-throughput

0.438

High

980358

RRN11
RNA polymerase I-specific transcription initiation factor RRN11

1

0

High-throughput

0.438

High

987186

BFR2
Protein BFR2

1

0

High-throughput

0.438

High

987188

ELP1
Elongator complex protein 1

1

0

High-throughput

0.438

High

987192

ADY3
Accumulates dyads protein 3

1

0

High-throughput

0.438

High

987204

GIN4
Serine/threonine-protein kinase GIN4

1

0

High-throughput

0.438

High

987207

MPC70
Sporulation-specific protein 21

1

0

High-throughput

0.438

High

987209

NOP56
Nucleolar protein 56

1

0

High-throughput

0.438

High

366933

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.426

High

705687

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.426

High

728322

DEF1
RNA polymerase II degradation factor 1

1

0

High-throughput

0.426

High

754999

RRP4
Exosome complex component RRP4

1

0

High-throughput

0.426

High

757033

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.426

High

766226

HSP7E
Heat shock protein SSC3, mitochondrial

1

0

High-throughput

0.426

High

865920

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.426

High

969364

NUP49
Nucleoporin NUP49/NSP49

1

1

High-throughput

0.417

High

987191

ATG20
Autophagy-related protein 20

1

1

High-throughput

0.417

High

985857

SN309
Pre-mRNA-splicing factor SNT309

2

0

Small-scale

0.328

High

987202

CWC2
Pre-mRNA-splicing factor CWC2

2

0

High-throughput

0.328

High

748393

ATG12
Ubiquitin-like protein ATG12

2

0

High-throughput

0.295

High

748932

BIT2
Probable target of rapamycin complex 2 subunit BIT2

2

0

High-throughput

0.295

High

778427

CHS6
Chitin biosynthesis protein CHS6

2

0

High-throughput

0.295

High

811077

SNX4
Sorting nexin-4

1

0

Small-scale

0.282

High

732792

RL14A
Large ribosomal subunit protein eL14A

1

0

Small-scale

0.279

Low

748090

NTC20
Pre-mRNA-splicing factor NTC20

1

0

Small-scale

0.279

Low

778639

PRP17
Pre-mRNA-processing factor 17

1

0

High-throughput

0.279

Low

732018

YKP3
Putative uncharacterized protein YKL153W

1

0

High-throughput

0.238

Low

747171

YBU6
Probable thioesterase YBR096W

1

0

High-throughput

0.238

Low

747235

EXO84
Exocyst complex component EXO84

1

0

High-throughput

0.238

Low

765866

BOI2
Protein BOI2

1

0

High-throughput

0.238

Low

772466

ALG5
Dolichyl-phosphate beta-glucosyltransferase

1

0

High-throughput

0.238

Low

796985

SNZ3
Probable pyridoxal 5'-phosphate synthase subunit SNZ3

1

0

High-throughput

0.238

Low

797758

IOC3
ISWI one complex protein 3

1

0

High-throughput

0.238

Low

837247

KEL2
Kelch repeat-containing protein 2

1

0

High-throughput

0.238

Low

856972

SC6B2
Protein transport protein SBH2

1

0

High-throughput

0.238

Low

860507

YG2G
Putative uncharacterized protein YGR079W

1

0

High-throughput

0.238

Low

861318

CENPQ
Inner kinetochore subunit OKP1

1

0

High-throughput

0.238

Low

864769

YN91
Uncharacterized membrane protein YNR062C

1

0

High-throughput

0.238

Low

987194

YL031
Putative uncharacterized protein YLR031W

1

0

High-throughput

0.238

Low

987195

YO036
Uncharacterized protein YOL036W

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024