Protein: VEGFA
Vascular endothelial growth factor A, long form (L-VEGF) (Vascular permeability factor) (VPF) [Cleaved into: N-VEGF; VEGFA]

Gene: VEGFA
Organism: Homo sapiens
Interactions: 53
UniProt ID: P15692

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001525 - angiogenesis
GO:0001541 - ovarian follicle development
GO:0001569 - branching involved in blood vessel morphogenesis
GO:0001570 - vasculogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

585441

VGFR2
Vascular endothelial growth factor receptor 2

19

20

Small-scale

0.988

High

164239

NRP1
Neuropilin-1

17

7

Small-scale

0.987

High

585434

VGFR1
Vascular endothelial growth factor receptor 1

12

20

Small-scale

0.980

High

585432

VEGFA
Vascular endothelial growth factor A, long form

7

10

Small-scale

0.963

High

585445

VEGFB
Vascular endothelial growth factor B

3

8

High-throughput

0.861

High

249030

NRP2
Neuropilin-2

2

7

Small-scale

0.778

High

585444

PLGF
Placenta growth factor

2

10

Small-scale

0.737

High

585455

HIF1A
Hypoxia-inducible factor 1-alpha

6

0

Small-scale

0.695

High

585449

PGBM
Basement membrane-specific heparan sulfate proteoglycan core protein

1

2

Small-scale

0.647

High

585447

NGAL
Neutrophil gelatinase-associated lipocalin

1

0

High-throughput

0.630

High

482668

SPRC
SPARC

2

3

Small-scale

0.602

High

585448

SMAD3
Mothers against decapentaplegic homolog 3

2

2

Small-scale

0.601

High

585452

SMAD4
Mothers against decapentaplegic homolog 4

2

2

Small-scale

0.601

High

585463

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

3

Small-scale

0.586

High

464672

CXB1
Gap junction beta-1 protein

2

0

High-throughput

0.580

High

585459

TM237
Transmembrane protein 237

2

0

High-throughput

0.580

High

585462

S35C2
Solute carrier family 35 member C2

2

0

High-throughput

0.580

High

384622

CRYAB
Alpha-crystallin B chain

2

1

Small-scale

0.563

High

388990

FINC
Fibronectin

1

4

Small-scale

0.561

High

585461

TMG4
Transmembrane gamma-carboxyglutamic acid protein 4

1

2

High-throughput

0.541

High

585437

CCN2
CCN family member 2

1

0

Small-scale

0.537

High

585457

ACTBL
Beta-actin-like protein 2

1

1

High-throughput

0.536

High

563130

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

585460

VPS35
Vacuolar protein sorting-associated protein 35

1

0

High-throughput

0.518

High

464788

SP1
Transcription factor Sp1

1

1

Small-scale

0.501

High

585439

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

1

Small-scale

0.501

High

585451

SP3
Transcription factor Sp3

1

1

Small-scale

0.501

High

585454

IBP7
Insulin-like growth factor-binding protein 7

1

3

Small-scale

0.501

High

585464

LYVE1
Lymphatic vessel endothelial hyaluronic acid receptor 1

1

1

Small-scale

0.501

High

585465

UBIA1
UbiA prenyltransferase domain-containing protein 1

1

0

Small-scale

0.486

High

399538

VTNC
Vitronectin

1

0

Small-scale

0.480

High

431510

AP2A
Transcription factor AP-2-alpha

1

0

Small-scale

0.480

High

178671

ANGP2
Angiopoietin-2

1

1

Small-scale

0.479

High

370540

FOS
Protein c-Fos

1

1

Small-scale

0.479

High

464413

TSP1
Thrombospondin-1

1

8

Small-scale

0.479

High

585435

PTPRB
Receptor-type tyrosine-protein phosphatase beta

1

4

Small-scale

0.479

High

585436

PTPRZ
Receptor-type tyrosine-protein phosphatase zeta

1

2

Small-scale

0.479

High

585443

STAT3
Signal transducer and activator of transcription 3

1

1

Small-scale

0.479

High

585453

SMAD2
Mothers against decapentaplegic homolog 2

1

2

Small-scale

0.479

High

169423

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

0

Small-scale

0.458

High

442572

RB
Retinoblastoma-associated protein

1

0

Small-scale

0.458

High

461111

HS90A
Heat shock protein HSP 90-alpha

1

0

Small-scale

0.458

High

533580

CLUS
Clusterin

1

0

Small-scale

0.458

High

566535

PDIA4
Protein disulfide-isomerase A4

1

0

Small-scale

0.458

High

585433

ITF2
Transcription factor 4

1

0

Small-scale

0.458

High

585438

HSP74
Heat shock 70 kDa protein 4

1

0

Small-scale

0.458

High

585440

CTNB1
Catenin beta-1

1

0

Small-scale

0.458

High

585446

GSK3B
Glycogen synthase kinase-3 beta

1

0

Small-scale

0.458

High

585458

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

0

Small-scale

0.458

High

585456

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.426

High

585450

U2AF1
Splicing factor U2AF 35 kDa subunit

1

0

High-throughput

0.282

High

585442

MOT8
Monocarboxylate transporter 8

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025