Protein: SMI1
Cell wall assembly regulator SMI1 (Killer toxin-resistance protein 4)

Gene: SMI1
Organism: Saccharomyces cerevisiae S288C
Interactions: 76
UniProt ID: P32566

Gene Ontology (top 5):
GO:0000131 - incipient cellular bud site
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005935 - cellular bud neck
GO:0007346 - regulation of mitotic cell cycle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

740254

SYYC
Tyrosine--tRNA ligase, cytoplasmic

3

0

Small-scale

0.651

High

740278

SLT2
Mitogen-activated protein kinase SLT2/MPK1

2

0

Small-scale

0.615

High

740283

PIN2
[PSI+] induction protein 2

2

0

High-throughput

0.587

High

740248

BCK2
Protein BCK2

2

0

Small-scale

0.577

High

740270

YAP4
AP-1-like transcription factor YAP4

2

0

Small-scale

0.577

High

740277

ACT
Actin

2

0

Small-scale

0.559

High

523388

HSP71
Heat shock protein SSA1

2

1

High-throughput

0.552

High

526203

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

740246

ATC5
Phospholipid-transporting ATPase DNF1

1

1

High-throughput

0.541

High

544202

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.528

High

740251

MID2
Cell wall integrity sensor MID2

1

0

High-throughput

0.518

High

740284

CHS5
Chitin biosynthesis protein CHS5

1

0

High-throughput

0.518

High

721782

XPO1
Exportin-1

1

0

High-throughput

0.513

High

740262

ATC3
Phospholipid-transporting ATPase DRS2

1

1

High-throughput

0.494

High

643264

BAS1
Myb-like DNA-binding protein BAS1

1

0

High-throughput

0.486

High

665791

KPC1
Protein kinase C-like 1

1

0

Small-scale

0.486

High

740287

RLM1
Transcription factor RLM1

1

0

Small-scale

0.486

High

392433

HSP82
ATP-dependent molecular chaperone HSP82

1

0

Small-scale

0.479

High

640549

UBC1
Ubiquitin-conjugating enzyme E2 1

1

0

Small-scale

0.479

High

699389

CIN8
Kinesin-like protein CIN8

1

0

Small-scale

0.479

High

740255

GBLP
Small ribosomal subunit protein RACK1

1

0

Small-scale

0.479

High

740271

BUD6
Bud site selection protein 6

1

0

Small-scale

0.479

High

477531

MYO1
Myosin-1

1

0

Small-scale

0.460

High

676791

BUD3
Bud site selection protein 3

1

0

Small-scale

0.460

High

740250

TOR1
Serine/threonine-protein kinase TOR1

1

0

High-throughput

0.460

High

740265

RV167
Reduced viability upon starvation protein 167

1

0

Small-scale

0.460

High

740267

NDC80
Kinetochore protein NDC80

1

0

Small-scale

0.460

High

706535

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

734891

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

740279

CIK1
Spindle pole body-associated protein CIK1

1

0

High-throughput

0.458

High

740281

ESP1
Separin

1

0

High-throughput

0.458

High

740286

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.458

High

603435

VATA
V-type proton ATPase catalytic subunit A

1

2

High-throughput

0.445

High

740245

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

740247

PRS7
26S proteasome regulatory subunit 7 homolog

1

1

High-throughput

0.445

High

740258

FKS1
1,3-beta-glucan synthase component FKS1

1

1

High-throughput

0.445

High

740280

PRS8
26S proteasome regulatory subunit 8 homolog

1

1

High-throughput

0.445

High

359177

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

High-throughput

0.426

High

740259

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.426

High

740266

IMB4
Importin subunit beta-4

1

0

High-throughput

0.426

High

366975

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.407

High

592108

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.407

High

597415

EF3A
Elongation factor 3A

1

1

High-throughput

0.407

High

740249

GCN1
eIF-2-alpha kinase activator GCN1

1

1

High-throughput

0.407

High

594913

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

2

0

Small-scale

0.307

High

740261

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

High-throughput

0.288

High

484275

KEX1
Pheromone-processing carboxypeptidase KEX1

1

0

High-throughput

0.282

High

535993

SEC7
ADP-ribosylation factor guanine nucleotide-exchange factor SEC7

1

0

High-throughput

0.282

High

560275

KEX2
Kexin

1

0

High-throughput

0.282

High

625884

HNM1
Choline transporter

1

0

High-throughput

0.282

High

740260

GGA2
ADP-ribosylation factor-binding protein GGA2

1

0

High-throughput

0.282

High

740263

FLC2
Flavin carrier protein 2

1

0

High-throughput

0.282

High

740272

COPB
Coatomer subunit beta

1

0

High-throughput

0.282

High

740273

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.282

High

740252

ANR2
Uncharacterized protein ANR2

1

0

High-throughput

0.269

Low

740253

JNM1
Nuclear migration protein JNM1

1

0

Small-scale

0.261

Low

740269

GVP36
Protein GVP36

1

0

Small-scale

0.261

Low

740276

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

Small-scale

0.261

Low

656295

PP2B1
Serine/threonine-protein phosphatase 2B catalytic subunit A1

1

0

Small-scale

0.251

Low

740282

NUP59
Nucleoporin ASM4

1

0

Small-scale

0.251

Low

740256

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

740285

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low

740264

MBO1
Gamma tubulin complex adapter SPC72

1

0

Small-scale

0.238

Low

358160

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.232

Low

364987

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.232

Low

386634

TBB
Tubulin beta chain

1

0

High-throughput

0.232

Low

394365

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

450550

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.232

Low

453485

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.232

Low

618564

FAS2
Fatty acid synthase subunit alpha

1

0

High-throughput

0.232

Low

734046

EF2
Elongation factor 2

1

0

High-throughput

0.232

Low

740257

OLA1
Obg-like ATPase 1

1

0

High-throughput

0.232

Low

740268

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

0

High-throughput

0.232

Low

740274

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

740275

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.232

Low

740288

HSP42
Heat shock protein 42

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025