Protein: PRP9
Pre-mRNA-splicing factor PRP9

Gene: PRP9
Organism: Saccharomyces cerevisiae S288C
Interactions: 106
UniProt ID: P19736

Gene Ontology (top 5):
GO:0000395 - mRNA 5'-splice site recognition
GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0003723 - RNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

625076

PRP21
Pre-mRNA-splicing factor PRP21

13

4

Small-scale

0.981

High

625119

SMD1
Small nuclear ribonucleoprotein Sm D1

4

1

High-throughput

0.892

High

625120

CUS1
Cold sensitive U2 snRNA suppressor 1

4

1

High-throughput

0.892

High

625098

RSMB
Small nuclear ribonucleoprotein-associated protein B

4

2

High-throughput

0.886

High

625141

NCBP2
Nuclear cap-binding protein subunit 2

4

2

Small-scale

0.873

High

625131

RSE1
Pre-mRNA-splicing factor RSE1

3

1

High-throughput

0.839

High

625101

RUXG
Small nuclear ribonucleoprotein G

3

4

High-throughput

0.830

High

625114

RUXF
Small nuclear ribonucleoprotein F

3

1

High-throughput

0.830

High

625104

SMD3
Small nuclear ribonucleoprotein Sm D3

2

4

High-throughput

0.776

High

625147

RUXE
Small nuclear ribonucleoprotein E

2

1

High-throughput

0.759

High

625154

HSH49
Protein HSH49

2

2

High-throughput

0.754

High

625106

LSM8
LSM2-LSM8 complex subunit LSM8

2

6

High-throughput

0.737

High

625137

PRP11
Pre-mRNA-splicing factor PRP11

6

2

Small-scale

0.736

High

625142

RU2A
U2 small nuclear ribonucleoprotein A'

6

1

Small-scale

0.726

High

625077

RU1A
U1 small nuclear ribonucleoprotein A

2

0

High-throughput

0.716

High

625099

LSM4
LSM complex subunit LSM4

1

2

High-throughput

0.691

High

625075

PRP19
Pre-mRNA-processing factor 19

4

3

Small-scale

0.691

High

625083

PRP8
Pre-mRNA-splicing factor 8

3

1

High-throughput

0.662

High

625079

BRR2
Pre-mRNA-splicing helicase BRR2

3

1

Small-scale

0.656

High

625134

SMD2
Small nuclear ribonucleoprotein Sm D2

1

1

High-throughput

0.618

High

625143

CWC2
Pre-mRNA-splicing factor CWC2

1

3

High-throughput

0.618

High

625125

CEF1
Pre-mRNA-splicing factor CEF1

2

3

High-throughput

0.611

High

625093

SP381
Pre-mRNA-splicing factor SPP381

2

0

High-throughput

0.595

High

625116

NAM8
Protein NAM8

1

0

High-throughput

0.586

High

625062

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

2

1

High-throughput

0.584

High

625123

CWC21
Pre-mRNA-splicing factor CWC21

2

0

High-throughput

0.576

High

625115

LSM3
LSM complex subunit LSM3

1

5

High-throughput

0.575

High

625084

NCBP1
Nuclear cap-binding protein complex subunit 1

2

0

High-throughput

0.559

High

625100

SSB2
Ribosome-associated molecular chaperone SSB2

2

2

High-throughput

0.552

High

625152

NSI1
RNA polymerase I termination factor

1

0

High-throughput

0.518

High

625109

TAF4
Transcription initiation factor TFIID subunit 4

1

1

High-throughput

0.508

High

625073

RPN12
26S proteasome regulatory subunit RPN12

1

0

High-throughput

0.493

High

625067

MRC1
Mediator of replication checkpoint protein 1

1

0

High-throughput

0.486

High

625081

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

0

High-throughput

0.486

High

625124

VPS72
Vacuolar protein sorting-associated protein 72

1

0

High-throughput

0.486

High

625130

ARO80
Transcriptional activator ARO80

1

0

High-throughput

0.486

High

625139

ULS1
ATP-dependent helicase ULS1

1

0

High-throughput

0.486

High

625144

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.486

High

625151

AHC1
Protein AHC1

1

0

High-throughput

0.486

High

625087

CENPA
Histone H3-like centromeric protein CSE4

1

1

High-throughput

0.481

High

625063

PRP5
Pre-mRNA-processing ATP-dependent RNA helicase PRP5

1

1

High-throughput

0.479

High

625065

BUD31
Pre-mRNA-splicing factor BUD31

1

1

High-throughput

0.479

High

625069

PRP45
Pre-mRNA-processing protein 45

1

1

High-throughput

0.479

High

625088

SN114
Pre-mRNA-splicing factor SNU114

1

1

High-throughput

0.479

High

625090

GBLP
Small ribosomal subunit protein RACK1

1

2

High-throughput

0.479

High

625102

MSL1
U2 small nuclear ribonucleoprotein B''

1

4

High-throughput

0.479

High

625103

PRP17
Pre-mRNA-processing factor 17

1

3

High-throughput

0.479

High

625108

SF3B1
U2 snRNP component HSH155

1

2

High-throughput

0.479

High

625129

SYF1
Pre-mRNA-splicing factor SYF1

1

3

High-throughput

0.479

High

625136

RDS3
Pre-mRNA-splicing factor RDS3

1

1

High-throughput

0.479

High

625145

BBP
Branchpoint-bridging protein

1

1

High-throughput

0.479

High

625146

CLF1
Pre-mRNA-splicing factor CLF1

1

4

High-throughput

0.479

High

625149

PRP46
Pre-mRNA-splicing factor PRP46

1

2

High-throughput

0.479

High

597628

MER1
Meiotic recombination 1 protein

1

0

Small-scale

0.460

High

602107

SPO12
Sporulation-specific protein 12

1

0

High-throughput

0.460

High

625085

CENPC
Inner kinetochore subunit MIF2

1

0

High-throughput

0.460

High

625097

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.460

High

625110

SKP1
Suppressor of kinetochore protein 1

1

0

High-throughput

0.460

High

625121

CENPP
Inner kinetochore subunit CTF19

1

0

High-throughput

0.460

High

625148

SCM3
Protein SCM3

1

0

High-throughput

0.460

High

409927

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

433437

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

434809

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

454864

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

501736

YSF3
RDS3 complex subunit 10

1

0

High-throughput

0.458

High

625064

ISY1
Pre-mRNA-splicing factor ISY1

1

0

High-throughput

0.458

High

625070

YJU2
Splicing factor YJU2

1

0

High-throughput

0.458

High

625071

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

625072

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

625074

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

0

High-throughput

0.458

High

625086

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

625089

YK21
Uncharacterized protein YKR041W

1

0

High-throughput

0.458

High

625092

SLT11
Pre-mRNA-splicing factor SLT11

1

0

High-throughput

0.458

High

625094

NTC20
Pre-mRNA-splicing factor NTC20

1

0

High-throughput

0.458

High

625105

CWC26
Pre-mRNA-splicing factor CWC26

1

0

High-throughput

0.458

High

625111

SYF2
Pre-mRNA-splicing factor SYF2

1

0

High-throughput

0.458

High

625113

CWC22
Pre-mRNA-splicing factor CWC22

1

0

High-throughput

0.458

High

625118

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

625122

SLU7
Pre-mRNA-splicing factor SLU7

1

0

High-throughput

0.458

High

625126

CWC15
Pre-mRNA-splicing factor CWC15

1

0

High-throughput

0.458

High

625127

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

625128

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

625133

SN309
Pre-mRNA-splicing factor SNT309

1

0

High-throughput

0.458

High

625135

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

625140

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

625150

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

1

0

Small-scale

0.458

High

625132

CIAO1
Cytosolic iron-sulfur protein assembly protein 1

1

2

High-throughput

0.457

High

625091

CDC27
Anaphase-promoting complex subunit CDC27

1

1

High-throughput

0.439

High

533398

MITF2
Mitochondrial translation factor 2

1

0

High-throughput

0.438

High

625153

PSF1
DNA replication complex GINS protein PSF1

1

0

High-throughput

0.438

High

625068

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.437

High

314839

SEM1
26S proteasome complex subunit SEM1

1

0

High-throughput

0.269

Low

625078

PT127
Putative mitochondrial translation system component PET127

1

0

High-throughput

0.265

Low

625117

MDM1
Structural protein MDM1

1

0

High-throughput

0.265

Low

625112

CENPQ
Inner kinetochore subunit OKP1

1

0

High-throughput

0.251

Low

149574

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.249

Low

435761

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.249

Low

514447

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

625066

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.249

Low

625082

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

625095

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

625096

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

625107

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

625080

ELM1
Serine/threonine-protein kinase ELM1

1

0

High-throughput

0.238

Low

625138

ADY3
Accumulates dyads protein 3

1

0

High-throughput

0.238

Low

578819

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025