Protein: IL25
Interleukin-25 (IL-25) (Interleukin-17E) (IL-17E)

Gene: IL25
Organism: Homo sapiens
Interactions: 44
UniProt ID: Q9H293

Gene Ontology (top 5):
GO:0002437 - inflammatory response to antigenic stimulus
GO:0005125 - cytokine activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0009620 - response to fungus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1431611

I17RB
Interleukin-17 receptor B

2

8

Small-scale

0.806

High

1390351

I17RA
Interleukin-17 receptor A

1

8

Small-scale

0.618

High

504761

FBSP1
F-box/SPRY domain-containing protein 1

2

3

High-throughput

0.601

High

290981

PPM1B
Protein phosphatase 1B

2

1

High-throughput

0.549

High

777010

PPM1A
Protein phosphatase 1A

2

1

High-throughput

0.549

High

63029

POTEF
POTE ankyrin domain family member F

1

1

High-throughput

0.536

High

535535

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.536

High

551822

CO6A1

1

1

High-throughput

0.536

High

551894

CO6A2

1

1

High-throughput

0.536

High

698022

CALR
Calreticulin

1

1

High-throughput

0.536

High

1249908

CREL2
Protein disulfide isomerase CRELD2

1

1

High-throughput

0.536

High

483637

CN37
2',3'-cyclic-nucleotide 3'-phosphodiesterase

1

0

High-throughput

0.513

High

532958

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.513

High

655008

ITA6
Integrin alpha-6

1

0

High-throughput

0.513

High

1420056

KPCD2
Serine/threonine-protein kinase D2

1

0

High-throughput

0.513

High

1431615

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

0

High-throughput

0.513

High

1289768

NT5D3
5'-nucleotidase domain-containing protein 3

1

1

High-throughput

0.489

High

1311106

UBR1
E3 ubiquitin-protein ligase UBR1

1

1

High-throughput

0.489

High

1311171

UBR2
E3 ubiquitin-protein ligase UBR2

1

1

High-throughput

0.489

High

1431610

NT5D2
5'-nucleotidase domain-containing protein 2

1

1

High-throughput

0.489

High

1431612

UGGG2
UDP-glucose:glycoprotein glucosyltransferase 2

1

1

High-throughput

0.489

High

1431613

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

1

High-throughput

0.489

High

1431614

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

1

1

High-throughput

0.489

High

396924

ESR1
Estrogen receptor

1

0

High-throughput

0.426

High

348261

DCMC
Malonyl-CoA decarboxylase, mitochondrial

2

0

High-throughput

0.313

High

136633

MANBA
Beta-mannosidase

1

0

High-throughput

0.279

Low

207878

ZZEF1
Zinc finger ZZ-type and EF-hand domain-containing protein 1

1

0

High-throughput

0.279

Low

252545

SEP15
Selenoprotein F

1

0

High-throughput

0.279

Low

253784

UGDH
UDP-glucose 6-dehydrogenase

1

0

High-throughput

0.279

Low

288012

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

0

High-throughput

0.279

Low

554840

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

1

0

High-throughput

0.279

Low

954609

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.279

Low

1154258

NPTX1
Neuronal pentraxin-1

1

0

High-throughput

0.279

Low

1193213

OFUT4
GDP-fucose protein O-fucosyltransferase 4

1

0

High-throughput

0.279

Low

1272072

SYPM
Probable proline--tRNA ligase, mitochondrial

1

0

High-throughput

0.279

Low

1280971

CTU1
Cytoplasmic tRNA 2-thiolation protein 1

1

0

High-throughput

0.279

Low

1409594

NIPS1
Protein NipSnap homolog 1

1

0

High-throughput

0.279

Low

1411841

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

0

High-throughput

0.279

Low

1431609

EHD1
EH domain-containing protein 1

1

0

High-throughput

0.279

Low

1431616

FBX2
F-box only protein 2

1

0

High-throughput

0.279

Low

596892

MGMT
Methylated-DNA--protein-cysteine methyltransferase

1

0

Small-scale

0.249

Low

1250197

LRC31
Leucine-rich repeat-containing protein 31

1

0

High-throughput

0.249

Low

1372472

TP4A1
Protein tyrosine phosphatase type IVA 1

1

0

High-throughput

0.232

Low

1387387

EOLA2
Protein EOLA2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025