Protein: BSCL2
Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein)

Gene: BSCL2
Organism: Homo sapiens
Interactions: 194
UniProt ID: Q96G97

Gene Ontology (top 5):
GO:0005543 - phospholipid binding
GO:0005789 - endoplasmic reticulum membrane
GO:0005811 - lipid droplet
GO:0016042 - lipid catabolic process
GO:0019915 - lipid storage

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1291997

USE1
Vesicle transport protein USE1

4

2

High-throughput

0.693

High

1291962

P121A
Nuclear envelope pore membrane protein POM 121

3

1

High-throughput

0.667

High

1291963

TMM19
Transmembrane protein 19

4

1

High-throughput

0.639

High

1260044

CHPT1
Cholinephosphotransferase 1

3

0

High-throughput

0.638

High

791346

NSG1
Neuronal vesicle trafficking-associated protein 1

2

1

High-throughput

0.633

High

1291975

SMIM3
Small integral membrane protein 3

3

1

High-throughput

0.619

High

276534

SC5D
Lathosterol oxidase

2

1

High-throughput

0.611

High

616638

GLRA2
Glycine receptor subunit alpha-2

3

3

High-throughput

0.609

High

905547

TSN5
Tetraspanin-5

3

4

High-throughput

0.609

High

941869

GBRE
Gamma-aminobutyric acid receptor subunit epsilon

3

5

High-throughput

0.609

High

1216527

ZDH17
Palmitoyltransferase ZDHHC17

3

1

High-throughput

0.609

High

1291476

TSN17
Tetraspanin-17

3

4

High-throughput

0.609

High

1068328

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.602

High

1291961

BSCL2
Seipin

1

2

High-throughput

0.590

High

577443

GBRG2
Gamma-aminobutyric acid receptor subunit gamma-2

2

4

High-throughput

0.574

High

802375

5HT3A
5-hydroxytryptamine receptor 3A

2

3

High-throughput

0.574

High

1081908

GBRA6
Gamma-aminobutyric acid receptor subunit alpha-6

2

4

High-throughput

0.574

High

237752

TSN2
Tetraspanin-2

2

3

High-throughput

0.560

High

253805

XYLK
Glycosaminoglycan xylosylkinase

2

1

High-throughput

0.560

High

1291965

GMCL1
Germ cell-less protein-like 1

2

1

High-throughput

0.560

High

72756

B4DET5
cDNA FLJ59484, highly similar to Nuclear envelope pore membrane protein POM 121

2

1

High-throughput

0.558

High

1078814

MSMO1
Methylsterol monooxygenase 1

1

1

High-throughput

0.536

High

1120724

ORML2
ORM1-like protein 2

1

1

High-throughput

0.536

High

1162104

RHDF2
Inactive rhomboid protein 2

1

1

High-throughput

0.536

High

1168246

CERS6
Ceramide synthase 6

1

3

High-throughput

0.536

High

1230214

ORML3
ORM1-like protein 3

1

1

High-throughput

0.536

High

1234288

CERS5
Ceramide synthase 5

1

3

High-throughput

0.536

High

1256017

RHBL4
Rhomboid-related protein 4

1

1

High-throughput

0.536

High

1291977

ELOV4
Very long chain fatty acid elongase 4

1

1

High-throughput

0.536

High

1291996

ELOV5
Very long chain fatty acid elongase 5

1

1

High-throughput

0.536

High

1292005

ZDHC9
Palmitoyltransferase ZDHHC9

1

1

High-throughput

0.536

High

474521

GPHRB
Golgi pH regulator B

2

1

High-throughput

0.533

High

225258

PLIN1
Perilipin-1

1

0

Small-scale

0.529

High

49218

SHSA3
Protein shisa-3 homolog

1

0

High-throughput

0.513

High

126843

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.513

High

168274

DEGS1
Sphingolipid delta(4)-desaturase DES1

1

0

High-throughput

0.513

High

174232

SPTC2
Serine palmitoyltransferase 2

1

0

High-throughput

0.513

High

234135

FADS1
Acyl-CoA

1

0

High-throughput

0.513

High

277449

DGAT1
Diacylglycerol O-acyltransferase 1

1

0

High-throughput

0.513

High

303940

YIF1A
Protein YIF1A

1

0

High-throughput

0.513

High

452262

HMOX1
Heme oxygenase 1

1

0

High-throughput

0.513

High

734423

CXG1
Gap junction gamma-1 protein

1

0

High-throughput

0.513

High

976754

TAP1
Antigen peptide transporter 1

1

0

High-throughput

0.513

High

1060100

STAR3
StAR-related lipid transfer protein 3

1

0

High-throughput

0.513

High

1065293

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

0

High-throughput

0.513

High

1167859

HACD2
Very-long-chain

1

0

High-throughput

0.513

High

1167890

DJC14
DnaJ homolog subfamily C member 14

1

0

High-throughput

0.513

High

1236152

FITM2
Acyl-coenzyme A diphosphatase FITM2

1

0

High-throughput

0.513

High

1283541

PAQR1
Adiponectin receptor protein 1

1

0

High-throughput

0.513

High

1285146

LDAF1
Lipid droplet assembly factor 1

1

0

High-throughput

0.513

High

1289064

NGBR
Dehydrodolichyl diphosphate synthase complex subunit NUS1

1

0

High-throughput

0.513

High

1291971

DERL1
Derlin-1

1

0

High-throughput

0.513

High

1291983

ARV1
Protein ARV1

1

0

High-throughput

0.513

High

1291987

RN121
E3 ubiquitin ligase RNF121

1

0

High-throughput

0.513

High

1292012

PEX16
Peroxisomal membrane protein PEX16

1

0

High-throughput

0.513

High

126046

UPK1A
Uroplakin-1a

1

5

High-throughput

0.489

High

168439

SCAM1
Secretory carrier-associated membrane protein 1

1

2

High-throughput

0.489

High

214785

PM34
Peroxisomal membrane protein PMP34

1

1

High-throughput

0.489

High

237835

TSN3
Tetraspanin-3

1

3

High-throughput

0.489

High

299706

SUN1
SUN domain-containing protein 1

1

1

High-throughput

0.489

High

310018

5HT3B
5-hydroxytryptamine receptor 3B

1

3

High-throughput

0.489

High

488338

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

1

High-throughput

0.489

High

570364

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

1

High-throughput

0.489

High

570875

ACHB2
Neuronal acetylcholine receptor subunit beta-2

1

1

High-throughput

0.489

High

798552

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

1

High-throughput

0.489

High

1037146

MTX1
Metaxin-1

1

1

High-throughput

0.489

High

1089548

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

1

High-throughput

0.489

High

1126171

MTX3
Metaxin-3

1

1

High-throughput

0.489

High

1132685

S35F1
Solute carrier family 35 member F1

1

1

High-throughput

0.489

High

1135917

DEP1A
DEP domain-containing protein 1A

1

1

High-throughput

0.489

High

1203206

LHPL1
LHFPL tetraspan subfamily member 1 protein

1

1

High-throughput

0.489

High

1221311

S35F2
Solute carrier family 35 member F2

1

1

High-throughput

0.489

High

1260757

DEP1B
DEP domain-containing protein 1B

1

1

High-throughput

0.489

High

1281081

SCAM4
Secretory carrier-associated membrane protein 4

1

2

High-throughput

0.489

High

1291968

DIRC2
Solute carrier family 49 member 4

1

1

High-throughput

0.489

High

1291981

PCDC1
Protocadherin alpha-C1

1

2

High-throughput

0.489

High

1291982

S2551
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

1

1

High-throughput

0.489

High

1291998

SUN2
SUN domain-containing protein 2

1

1

High-throughput

0.489

High

1291999

TSN16
Tetraspanin-16

1

3

High-throughput

0.489

High

1292008

RHBD3
Rhomboid domain-containing protein 3

1

3

High-throughput

0.489

High

1292009

PCDB3
Protocadherin beta-3

1

1

High-throughput

0.489

High

1292010

PCDGH
Protocadherin gamma-B5

1

1

High-throughput

0.489

High

1292011

FLVC1
Heme transporter FLVCR1

1

1

High-throughput

0.489

High

1292013

LHPL6
LHFPL tetraspan subfamily member 6 protein

1

1

High-throughput

0.489

High

514451

PSPC
Surfactant protein C

1

1

High-throughput

0.481

High

1187513

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

1

High-throughput

0.481

High

1235410

TR1L1
Translocating chain-associated membrane protein 1-like 1

1

3

High-throughput

0.481

High

1236300

SERP2
Stress-associated endoplasmic reticulum protein 2

1

3

High-throughput

0.481

High

1291980

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

1

High-throughput

0.481

High

1292014

SERP1
Stress-associated endoplasmic reticulum protein 1

1

3

High-throughput

0.481

High

654660

CALX
Calnexin

1

0

Small-scale

0.458

High

1291991

TLR9
Toll-like receptor 9

1

0

Small-scale

0.458

High

1292004

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

0

High-throughput

0.458

High

58320

TM218
Transmembrane protein 218

1

1

High-throughput

0.439

High

67283

CRTP1
Cysteine-rich tail protein 1

1

1

High-throughput

0.439

High

131941

UPK2
Uroplakin-2

1

1

High-throughput

0.439

High

207476

LAT
Linker for activation of T-cells family member 1

1

1

High-throughput

0.439

High

313031

BMP10
Bone morphogenetic protein 10

1

1

High-throughput

0.439

High

829969

HXA1
Homeobox protein Hox-A1

1

1

High-throughput

0.439

High

991078

CXCL9
C-X-C motif chemokine 9

1

1

High-throughput

0.439

High

1022749

MALL
MAL-like protein

1

1

High-throughput

0.439

High

1079399

VAMP3
Vesicle-associated membrane protein 3

1

1

High-throughput

0.439

High

1166165

OLFM4
Olfactomedin-4

1

1

High-throughput

0.439

High

1191240

CPEB2
Cytoplasmic polyadenylation element-binding protein 2

1

1

Small-scale

0.439

High

1202952

ANR46
Ankyrin repeat domain-containing protein 46

1

2

High-throughput

0.439

High

1220527

TARG1
Trafficking regulator of GLUT4 1

1

1

High-throughput

0.439

High

1235908

CLD19
Claudin-19

1

1

High-throughput

0.439

High

1246120

B4GN2
Beta-1,4 N-acetylgalactosaminyltransferase 2

1

1

High-throughput

0.439

High

1291656

CKLF7
CKLF-like MARVEL transmembrane domain-containing protein 7

1

1

High-throughput

0.439

High

1291967

SMIP9
Protein SPMIP9

1

1

High-throughput

0.439

High

1291979

TM222
Transmembrane protein 222

1

1

High-throughput

0.439

High

1291993

RPRM
Protein reprimo

1

1

High-throughput

0.439

High

168573

SCAM2
Secretory carrier-associated membrane protein 2

1

2

High-throughput

0.437

High

205825

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

81831

GPHRA
Golgi pH regulator A

1

1

High-throughput

0.407

High

257094

DJC13
DnaJ homolog subfamily C member 13

3

0

High-throughput

0.347

High

1170478

TMPPE
Transmembrane protein with metallophosphoesterase domain

3

0

High-throughput

0.347

High

1205541

TMM25
Transmembrane protein 25

3

0

High-throughput

0.347

High

1252075

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

3

0

High-throughput

0.347

High

1291970

S39A3
Zinc transporter ZIP3

3

0

High-throughput

0.347

High

206513

B4GA1
Beta-1,4-glucuronyltransferase 1

2

0

High-throughput

0.328

High

1291412

ASIC4
Acid-sensing ion channel 4

2

0

High-throughput

0.328

High

996252

CD47
Leukocyte surface antigen CD47

2

0

High-throughput

0.318

High

1223557

K2013
Uncharacterized protein KIAA2013

2

0

High-throughput

0.318

High

1240524

ATAD1
Outer mitochondrial transmembrane helix translocase

2

0

High-throughput

0.318

High

1292007

HDGR3
Hepatoma-derived growth factor-related protein 3

2

0

High-throughput

0.318

High

110660

SMLR1
Small leucine-rich protein 1

1

0

High-throughput

0.299

High

1291986

PKHF2
Pleckstrin homology domain-containing family F member 2

1

0

High-throughput

0.299

High

49152

TM223
Transmembrane protein 223

1

0

High-throughput

0.279

Low

49484

CLRN2
Clarin-2

1

0

High-throughput

0.279

Low

63424

MET15
12S rRNA N4-methylcytidine

1

0

High-throughput

0.279

Low

129134

IFRD1
Interferon-related developmental regulator 1

1

0

High-throughput

0.279

Low

203593

MBTP2
Membrane-bound transcription factor site-2 protease

1

0

High-throughput

0.279

Low

300594

ENDD1
Endonuclease domain-containing 1 protein

1

0

High-throughput

0.279

Low

309613

GOSR1
Golgi SNAP receptor complex member 1

1

0

High-throughput

0.279

Low

327020

ABHGA
Phosphatidylserine lipase ABHD16A

1

0

High-throughput

0.279

Low

439160

SYPH
Synaptophysin

1

0

High-throughput

0.279

Low

540328

GPIX
Platelet glycoprotein IX

1

0

High-throughput

0.279

Low

603356

FUT4
Alpha-(1,3)-fucosyltransferase 4

1

0

High-throughput

0.279

Low

648063

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

0

High-throughput

0.279

Low

781209

ETV3
ETS translocation variant 3

1

0

High-throughput

0.279

Low

1019260

TM115
Transmembrane protein 115

1

0

High-throughput

0.279

Low

1078224

CD226
CD226 antigen

1

0

High-throughput

0.279

Low

1083589

SGCA
Alpha-sarcoglycan

1

0

High-throughput

0.279

Low

1108500

TMM95
Sperm-egg fusion protein TMEM95

1

0

High-throughput

0.279

Low

1125095

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.279

Low

1129718

RTP2
Receptor-transporting protein 2

1

0

High-throughput

0.279

Low

1131288

MANEA
Glycoprotein endo-alpha-1,2-mannosidase

1

0

High-throughput

0.279

Low

1137296

TM164
Transmembrane protein 164

1

0

High-throughput

0.279

Low

1147994

LMBD2
G-protein coupled receptor-associated protein LMBRD2

1

0

High-throughput

0.279

Low

1154551

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.279

Low

1156216

SCMC1
Mitochondrial adenyl nucleotide antiporter SLC25A24

1

0

High-throughput

0.279

Low

1156770

MFS12
Major facilitator superfamily domain-containing protein 12

1

0

High-throughput

0.279

Low

1204724

TCAM2
TIR domain-containing adapter molecule 2

1

0

High-throughput

0.279

Low

1219411

LRC8A
Volume-regulated anion channel subunit LRRC8A

1

0

High-throughput

0.279

Low

1245949

MFSD8
Major facilitator superfamily domain-containing protein 8

1

0

High-throughput

0.279

Low

1281773

IGSF8
Immunoglobulin superfamily member 8

1

0

High-throughput

0.279

Low

1283907

S2546
Mitochondrial outer membrane protein SLC25A46

1

0

High-throughput

0.279

Low

1287070

TLCD1
TLC domain-containing protein 1

1

0

High-throughput

0.279

Low

1289487

YIPF6
Protein YIPF6

1

0

High-throughput

0.279

Low

1291964

TM41A
Transmembrane protein 41A

1

0

High-throughput

0.279

Low

1291966

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

0

High-throughput

0.279

Low

1291969

PGAP4
Post-GPI attachment to proteins factor 4

1

0

High-throughput

0.279

Low

1291973

FUT8
Alpha-(1,6)-fucosyltransferase

1

0

High-throughput

0.279

Low

1291976

YIPF3
Protein YIPF3

1

0

High-throughput

0.279

Low

1291984

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.279

Low

1291985

NSUN3
tRNA

1

0

High-throughput

0.279

Low

1291989

NEK6
Serine/threonine-protein kinase Nek6

1

0

High-throughput

0.279

Low

1291990

GPC5C
G-protein coupled receptor family C group 5 member C

1

0

High-throughput

0.279

Low

1291992

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.279

Low

1291995

CLDN1
Claudin domain-containing protein 1

1

0

High-throughput

0.279

Low

1292000

TAOK2
Serine/threonine-protein kinase TAO2

1

0

High-throughput

0.279

Low

1292001

TIM
Protein timeless homolog

1

0

High-throughput

0.279

Low

1292003

CE164
Centrosomal protein of 164 kDa

1

0

High-throughput

0.279

Low

1292006

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.279

Low

121416

HYAS3
Hyaluronan synthase 3

1

0

High-throughput

0.269

Low

557485

PECA1
Platelet endothelial cell adhesion molecule

1

0

High-throughput

0.268

Low

868295

ATX3
Ataxin-3

1

0

High-throughput

0.268

Low

1287332

OPTN
Optineurin

1

0

High-throughput

0.268

Low

1291978

SKI8
Superkiller complex protein 8

1

0

High-throughput

0.268

Low

1291988

CAN10
Calpain-10

1

0

High-throughput

0.268

Low

1292002

CSN3
COP9 signalosome complex subunit 3

1

0

High-throughput

0.268

Low

1291974

TRI54
Tripartite motif-containing protein 54

1

0

High-throughput

0.251

Low

329889

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

530258

ICAM2
Intercellular adhesion molecule 2

1

0

High-throughput

0.249

Low

719057

PHB1
Prohibitin 1

1

0

High-throughput

0.249

Low

1063550

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.249

Low

1166640

I20RB
Interleukin-20 receptor subunit beta

1

0

High-throughput

0.249

Low

1254987

MCLN3
Mucolipin-3

1

0

High-throughput

0.249

Low

1291994

T106B
Transmembrane protein 106B

1

0

High-throughput

0.249

Low

1131801

CE170
Centrosomal protein of 170 kDa

1

0

High-throughput

0.232

Low

1199989

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

0

High-throughput

0.232

Low

1291972

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024