Protein: LYPL1
Lysophospholipase-like protein 1 (EC 3.1.2.22)

Gene: LYPL1, LYPLAL1
Organism: Homo sapiens
Interactions: 66
UniProt ID: Q5VWZ2

Gene Ontology (top 5):
GO:0004622 - phosphatidylcholine lysophospholipase activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0008474 - palmitoyl-(protein) hydrolase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1219168

CT55
Cancer/testis antigen 55

2

0

High-throughput

0.580

High

279793

CISY
Citrate synthase, mitochondrial

2

0

High-throughput

0.559

High

664058

PRTN3
Myeloblastin

1

1

High-throughput

0.536

High

830903

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

897304

CDK7
Cyclin-dependent kinase 7

1

1

High-throughput

0.479

High

1090432

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

1

High-throughput

0.479

High

1219161

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

1219174

EFGM
Elongation factor G, mitochondrial

1

1

High-throughput

0.479

High

1219182

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

241961

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

281978

MPPB
Mitochondrial-processing peptidase subunit beta

1

0

High-throughput

0.458

High

293829

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

471080

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.458

High

519137

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

532661

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

629913

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

786128

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.458

High

809674

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.458

High

828809

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

841783

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

851920

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

856286

IF2M
Translation initiation factor IF-2, mitochondrial

1

0

High-throughput

0.458

High

1048556

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1058075

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1087419

GRSF1
G-rich sequence factor 1

1

0

High-throughput

0.458

High

1128741

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

1142570

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

1162369

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.458

High

1207038

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1219160

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

1219162

TAXB1
Tax1-binding protein 1

1

0

High-throughput

0.458

High

1219164

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.458

High

1219165

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1219169

TOPB1
DNA topoisomerase 2-binding protein 1

1

0

High-throughput

0.458

High

1219171

FAKD4
FAST kinase domain-containing protein 4

1

0

High-throughput

0.458

High

1219172

SCLT1
Sodium channel and clathrin linker 1

1

0

High-throughput

0.458

High

1219176

TR61B
tRNA

1

0

High-throughput

0.458

High

1219177

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

0

High-throughput

0.458

High

1219179

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

0

High-throughput

0.458

High

1219180

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

0

High-throughput

0.458

High

1219183

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

538765

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

1

High-throughput

0.445

High

1209237

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.445

High

1099999

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.437

High

64877

RCCD1
RCC1 domain-containing protein 1

1

0

High-throughput

0.426

High

653374

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

1098712

NDK3
Nucleoside diphosphate kinase 3

1

0

High-throughput

0.426

High

1219163

OSTM1
Osteopetrosis-associated transmembrane protein 1

1

0

High-throughput

0.426

High

1219166

SETD6
N-lysine methyltransferase SETD6

1

0

High-throughput

0.426

High

1219175

CCM2
Cerebral cavernous malformations 2 protein

1

0

High-throughput

0.426

High

1219178

CHIA
Acidic mammalian chitinase

1

0

High-throughput

0.426

High

1219184

TRAK1
Trafficking kinesin-binding protein 1

1

0

High-throughput

0.426

High

73817

C1T9B
Complement C1q and tumor necrosis factor-related protein 9B

1

1

High-throughput

0.407

High

388640

C1QA
Complement C1q subcomponent subunit A

1

1

High-throughput

0.407

High

260880

RAMP3
Receptor activity-modifying protein 3

2

0

High-throughput

0.313

High

608288

EGLN
Endoglin

1

0

High-throughput

0.279

Low

1193245

CLM2
CMRF35-like molecule 2

1

0

High-throughput

0.279

Low

1219181

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

1

0

High-throughput

0.279

Low

327059

NXPH3
Neurexophilin-3

1

0

High-throughput

0.232

Low

449610

KLK1
Kallikrein-1

1

0

High-throughput

0.232

Low

479060

CEL3A
Chymotrypsin-like elastase family member 3A

1

0

High-throughput

0.232

Low

754042

CD80
T-lymphocyte activation antigen CD80

1

0

High-throughput

0.232

Low

976814

LCN6
Epididymal-specific lipocalin-6

1

0

High-throughput

0.232

Low

1219167

F174A
Membrane protein FAM174A

1

0

High-throughput

0.232

Low

1219170

SNX21
Sorting nexin-21

1

0

High-throughput

0.232

Low

1219173

OPALI
Opalin

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025