Protein: TBCD
Tubulin-specific chaperone D (Beta-tubulin cofactor D) (tfcD) (SSD-1) (Tubulin-folding cofactor D)

Gene: TBCD
Organism: Homo sapiens
Interactions: 100
UniProt ID: Q9BTW9

Gene Ontology (top 5):
GO:0000226 - microtubule cytoskeleton organization
GO:0000278 - mitotic cell cycle
GO:0005096 - GTPase activator activity
GO:0005737 - cytoplasm
GO:0005813 - centrosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

783120

ARL2
ADP-ribosylation factor-like protein 2

5

3

Small-scale

0.721

High

1118576

TBB2A
Tubulin beta-2A chain

3

5

High-throughput

0.667

High

1413735

TBB2B
Tubulin beta-2B chain

3

5

High-throughput

0.667

High

457660

TBB5
Tubulin beta chain

2

5

High-throughput

0.628

High

997485

TBB4B
Tubulin beta-4B chain

2

5

High-throughput

0.628

High

262294

SCN2B
Sodium channel regulatory subunit beta-2

3

2

High-throughput

0.609

High

774588

BASI
Basigin

3

1

High-throughput

0.609

High

699576

IL1R2
Interleukin-1 receptor type 2

2

0

High-throughput

0.602

High

1413751

NPTN
Neuroplastin

2

1

High-throughput

0.549

High

436730

KPCB
Protein kinase C beta type

2

0

High-throughput

0.547

High

988664

RAC1
Ras-related C3 botulinum toxin substrate 1

2

0

High-throughput

0.547

High

408148

TBB4A
Tubulin beta-4A chain

1

5

High-throughput

0.536

High

698362

MAP4
Microtubule-associated protein 4

1

1

High-throughput

0.536

High

1191957

TBB8
Tubulin beta-8 chain

1

5

High-throughput

0.536

High

1413750

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

1

High-throughput

0.536

High

928537

TERF1
Telomeric repeat-binding factor 1

1

0

High-throughput

0.529

High

296821

ST1C4
Sulfotransferase 1C4

1

0

High-throughput

0.513

High

347292

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.513

High

445250

S10A6
Protein S100-A6

1

0

High-throughput

0.513

High

1385384

ARMC5
Armadillo repeat-containing protein 5

1

0

High-throughput

0.513

High

1394973

VCIP1
Deubiquitinating protein VCPIP1

1

0

High-throughput

0.513

High

1402700

TCPQM
T-complex protein 1 subunit theta-like 2

1

0

High-throughput

0.513

High

1413736

DUS16
Dual specificity protein phosphatase 16

1

0

High-throughput

0.513

High

783170

ARL3
ADP-ribosylation factor-like protein 3

1

3

Small-scale

0.501

High

831340

CCNF
Cyclin-F

1

0

High-throughput

0.493

High

182751

GP182
G-protein coupled receptor 182

1

1

High-throughput

0.489

High

1413738

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

1

1

High-throughput

0.489

High

1413745

SCN3B
Sodium channel regulatory subunit beta-3

1

2

High-throughput

0.489

High

181935

SMAD9
Mothers against decapentaplegic homolog 9

1

0

High-throughput

0.486

High

423033

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

1413739

COMD4
COMM domain-containing protein 4

1

0

Small-scale

0.480

High

530309

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.479

High

242769

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

537814

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

599622

STMN1
Stathmin

1

0

High-throughput

0.458

High

791677

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

935075

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

959240

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.458

High

994354

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

0

Small-scale

0.458

High

1005038

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1114165

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1161380

HIF1A
Hypoxia-inducible factor 1-alpha

1

0

High-throughput

0.458

High

1255315

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1334855

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1347856

RIN3
Ras and Rab interactor 3

1

0

High-throughput

0.458

High

1383237

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.458

High

1397381

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1413741

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1413743

T11L1
T-complex protein 11-like protein 1

1

0

High-throughput

0.458

High

1413748

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1413752

NEMO
NF-kappa-B essential modulator

1

0

High-throughput

0.458

High

487699

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.437

High

166403

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

0

High-throughput

0.426

High

1228650

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

2

0

High-throughput

0.328

High

1293899

VSIG1
V-set and immunoglobulin domain-containing protein 1

2

0

High-throughput

0.328

High

1413742

LRRC4
Leucine-rich repeat-containing protein 4

2

0

High-throughput

0.328

High

1413749

CRYL1
Lambda-crystallin homolog

2

0

High-throughput

0.328

High

106576

APRIO
Alternative prion protein

2

0

High-throughput

0.305

High

1383370

ACD
Adrenocortical dysplasia protein homolog

1

0

High-throughput

0.299

High

1327787

SH2D3
SH2 domain-containing protein 3C

2

0

High-throughput

0.298

High

1413744

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.288

High

558375

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.282

High

787779

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

0

High-throughput

0.282

High

388288

GLPA
Glycophorin-A

1

0

High-throughput

0.279

Low

914335

EFNA4
Ephrin-A4

1

0

High-throughput

0.279

Low

1041795

PPARD
Peroxisome proliferator-activated receptor delta

1

0

High-throughput

0.279

Low

1101648

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

0

High-throughput

0.279

Low

1129868

EPN4
Clathrin interactor 1

1

0

High-throughput

0.279

Low

1142523

PDCD1
Programmed cell death protein 1

1

0

High-throughput

0.279

Low

1292402

OSTM1
Osteopetrosis-associated transmembrane protein 1

1

0

High-throughput

0.279

Low

1324854

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.279

Low

1325830

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1325911

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.279

Low

1350873

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

1390342

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.279

Low

1413737

CDHR2
Cadherin-related family member 2

1

0

High-throughput

0.279

Low

1413740

F234A
Protein FAM234A

1

0

High-throughput

0.279

Low

1413747

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

980247

H4
Histone H4

1

0

High-throughput

0.269

Low

880955

MTR1B
Melatonin receptor type 1B

1

0

High-throughput

0.265

Low

175417

PLXB2
Plexin-B2

1

0

High-throughput

0.249

Low

412534

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

418398

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

589563

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

696371

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

769041

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

895214

5HT6R
5-hydroxytryptamine receptor 6

1

0

Small-scale

0.249

Low

1137999

TNIP1
TNFAIP3-interacting protein 1

1

0

High-throughput

0.249

Low

1141602

OZF
Zinc finger protein OZF

1

0

High-throughput

0.249

Low

1178349

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1249169

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1252744

ZN836
Zinc finger protein 836

1

0

High-throughput

0.249

Low

1276723

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1386346

FAF2
FAS-associated factor 2

1

0

High-throughput

0.249

Low

1403403

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.249

Low

1413746

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.249

Low

336300

DEXI
Dexamethasone-induced protein

1

0

High-throughput

0.238

Low

1118

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.232

Low

231629

PRKY
Putative serine/threonine-protein kinase PRKY

1

0

High-throughput

0.232

Low

1253653

PKHG7
Pleckstrin homology domain-containing family G member 7

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025