Protein: TM186
Transmembrane protein 186

Gene: TM186, TMEM186
Organism: Homo sapiens
Interactions: 83
UniProt ID: Q96B77

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0032981 - mitochondrial respiratory chain complex I assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

967336

TSN5
Tetraspanin-5

3

4

High-throughput

0.609

High

1242894

S39A4
Zinc transporter ZIP4

3

2

High-throughput

0.609

High

1360191

5HT3C
5-hydroxytryptamine receptor 3C

3

1

High-throughput

0.609

High

1384190

ZDHC7
Palmitoyltransferase ZDHHC7

3

1

High-throughput

0.609

High

722567

CTR1
High affinity cationic amino acid transporter 1

3

1

High-throughput

0.604

High

760485

SDC2
Syndecan-2

3

1

High-throughput

0.604

High

835353

VIPR2
Vasoactive intestinal polypeptide receptor 2

3

1

High-throughput

0.604

High

251243

RNBP6
Ran-binding protein 6

2

0

High-throughput

0.602

High

855369

5HT3A
5-hydroxytryptamine receptor 3A

2

1

High-throughput

0.574

High

622088

CD53
Leukocyte surface antigen CD53

2

3

High-throughput

0.549

High

726687

SDC4
Syndecan-4

2

1

High-throughput

0.549

High

1384181

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

0

High-throughput

0.513

High

166011

FFAR1
Free fatty acid receptor 1

1

2

High-throughput

0.489

High

252560

TSN1
Tetraspanin-1

1

4

High-throughput

0.489

High

349524

TSN15
Tetraspanin-15

1

4

High-throughput

0.489

High

485977

CD3G
T-cell surface glycoprotein CD3 gamma chain

1

1

High-throughput

0.489

High

618407

TSN8
Tetraspanin-8

1

4

High-throughput

0.489

High

640534

TA2R
Thromboxane A2 receptor

1

1

High-throughput

0.489

High

733038

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

1

High-throughput

0.489

High

832438

OPRX
Nociceptin receptor

1

1

High-throughput

0.489

High

956969

CXCR4
C-X-C chemokine receptor type 4

1

2

High-throughput

0.489

High

1192274

ZACN
Ligand-gated cation channel ZACN

1

2

High-throughput

0.489

High

1348617

S7A14
Solute carrier family 7 member 14

1

1

High-throughput

0.489

High

1384177

ZDH12
Palmitoyltransferase ZDHHC12

1

2

High-throughput

0.489

High

1384180

CML1
Chemerin-like receptor 1

1

2

High-throughput

0.489

High

1384183

TSN10
Tetraspanin-10

1

4

High-throughput

0.489

High

1384186

GPR35
G-protein coupled receptor 35

1

2

High-throughput

0.489

High

1384187

S6A20
Sodium- and chloride-dependent transporter XTRP3

1

2

High-throughput

0.489

High

1384198

SC6A5
Sodium- and chloride-dependent glycine transporter 2

1

2

High-throughput

0.489

High

1384173

OMA1
Metalloendopeptidase OMA1, mitochondrial

1

0

High-throughput

0.458

High

1384175

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

0

High-throughput

0.458

High

407201

CD3D
T-cell surface glycoprotein CD3 delta chain

1

1

High-throughput

0.407

High

886116

CXCR3
C-X-C chemokine receptor type 3

1

1

High-throughput

0.407

High

1229419

S6A19
Sodium-dependent neutral amino acid transporter B(0)AT1

1

2

High-throughput

0.407

High

1363416

S39A7
Zinc transporter SLC39A7

1

2

High-throughput

0.407

High

1384188

S39A2
Zinc transporter ZIP2

1

2

High-throughput

0.407

High

1358016

TM171
Transmembrane protein 171

4

0

High-throughput

0.360

High

1278621

HEAT3
HEAT repeat-containing protein 3

4

0

High-throughput

0.358

High

1200247

T4S20
Transmembrane 4 L6 family member 20

3

0

High-throughput

0.347

High

1366164

LPAR1
Lysophosphatidic acid receptor 1

3

0

High-throughput

0.347

High

1384199

FADS3
Fatty acid desaturase 3

3

0

High-throughput

0.345

High

1198739

MPPE1
Metallophosphoesterase 1

2

0

High-throughput

0.328

High

1247503

POTEE
POTE ankyrin domain family member E

2

0

High-throughput

0.328

High

1259243

NCKX5
Sodium/potassium/calcium exchanger 5

2

0

High-throughput

0.328

High

1350031

SPP2B
Signal peptide peptidase-like 2B

2

0

High-throughput

0.328

High

1384179

GCP5
Gamma-tubulin complex component 5

2

0

High-throughput

0.328

High

1384185

IPPK
Inositol-pentakisphosphate 2-kinase

2

0

High-throughput

0.328

High

1307595

ZDH17
Palmitoyltransferase ZDHHC17

1

0

High-throughput

0.282

High

164951

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

0

High-throughput

0.279

Low

248497

O10H2
Olfactory receptor 10H2

1

0

High-throughput

0.279

Low

469525

SYPH
Synaptophysin

1

0

High-throughput

0.279

Low

692245

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

1

0

High-throughput

0.279

Low

906332

GPC3
Glypican-3

1

0

High-throughput

0.279

Low

914548

EFNA5
Ephrin-A5

1

0

High-throughput

0.279

Low

1023418

AT11A
Phospholipid-transporting ATPase IH

1

0

High-throughput

0.279

Low

1185891

TMM95
Sperm-egg fusion protein TMEM95

1

0

High-throughput

0.279

Low

1200368

KCP3
Keratinocyte-associated protein 3

1

0

High-throughput

0.279

Low

1317075

CKLF8
CKLF-like MARVEL transmembrane domain-containing protein 8

1

0

High-throughput

0.279

Low

1347186

LHPL5
LHFPL tetraspan subfamily member 5 protein

1

0

High-throughput

0.279

Low

1370789

PTPR2
Receptor-type tyrosine-protein phosphatase N2

1

0

High-throughput

0.279

Low

1384171

S67A1
Solute carrier family 67 member A1

1

0

High-throughput

0.279

Low

1384172

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

0

High-throughput

0.279

Low

1384176

PLPR2
Phospholipid phosphatase-related protein type 2

1

0

High-throughput

0.279

Low

1384178

CREL1
Protein disulfide isomerase CRELD1

1

0

High-throughput

0.279

Low

1384184

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.279

Low

1384191

SC5A4
Probable glucose sensor protein SLC5A4

1

0

High-throughput

0.279

Low

1384192

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

0

High-throughput

0.279

Low

1384193

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

1384194

LAMP5
Lysosome-associated membrane glycoprotein 5

1

0

High-throughput

0.279

Low

1384195

DSE
Dermatan-sulfate epimerase

1

0

High-throughput

0.279

Low

387138

TNNC2
Troponin C, skeletal muscle

1

0

High-throughput

0.269

Low

570541

GFAP
Glial fibrillary acidic protein

1

0

High-throughput

0.268

Low

650339

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.268

Low

1360710

JPH3
Junctophilin-3

1

0

High-throughput

0.268

Low

1384196

UBQL1
Ubiquilin-1

1

0

High-throughput

0.268

Low

1384200

Q9Y649
GW128

1

0

High-throughput

0.268

Low

611281

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.249

Low

1384197

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

0

High-throughput

0.249

Low

1098084

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

0

High-throughput

0.232

Low

1242193

NPAL3
NIPA-like protein 3

1

0

High-throughput

0.232

Low

1384174

SAAL1
Protein SAAL1

1

0

High-throughput

0.232

Low

1384182

CINP
Cyclin-dependent kinase 2-interacting protein

1

0

High-throughput

0.232

Low

1384189

S52A3
Solute carrier family 52, riboflavin transporter, member 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025