Protein: EMC7
Endoplasmic reticulum membrane protein complex subunit 7 (ER membrane protein complex subunit 7)

Gene: EMC7
Organism: Homo sapiens
Interactions: 163
UniProt ID: Q9NPA0

Gene Ontology (top 5):
GO:0005789 - endoplasmic reticulum membrane
GO:0016020 - membrane
GO:0030246 - carbohydrate binding
GO:0045050 - protein insertion into ER membrane by stop-transfer membrane-anchor sequence
GO:0071816 - tail-anchored membrane protein insertion into ER membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1330405

EMC1
ER membrane protein complex subunit 1

6

1

High-throughput

0.949

High

1136376

EMC2
ER membrane protein complex subunit 2

9

1

Small-scale

0.753

High

215656

EMC8
ER membrane protein complex subunit 8

5

2

High-throughput

0.720

High

1205491

EMC4
ER membrane protein complex subunit 4

5

1

High-throughput

0.720

High

1217117

EMC10
ER membrane protein complex subunit 10

5

1

High-throughput

0.720

High

1446114

EMC3
ER membrane protein complex subunit 3

5

1

High-throughput

0.720

High

1446126

EMC9
ER membrane protein complex subunit 9

5

2

High-throughput

0.720

High

1326913

EMC5
ER membrane protein complex subunit 5

7

0

High-throughput

0.717

High

1446110

FBX6
F-box only protein 6

4

1

High-throughput

0.683

High

926849

VMAT1
Chromaffin granule amine transporter

3

1

High-throughput

0.667

High

1415008

EMC6
ER membrane protein complex subunit 6

3

1

High-throughput

0.662

High

1405348

P2RX4
P2X purinoceptor 4

3

0

High-throughput

0.638

High

889012

TMEDA
Transmembrane emp24 domain-containing protein 10

2

4

High-throughput

0.611

High

1093585

TRDN
Triadin

2

0

High-throughput

0.602

High

1180868

S4A8
Electroneutral sodium bicarbonate exchanger 1

2

0

High-throughput

0.602

High

1146643

TMED2
Transmembrane emp24 domain-containing protein 2

2

4

High-throughput

0.601

High

1446121

FBX2
F-box only protein 2

2

1

High-throughput

0.601

High

699157

CALX
Calnexin

2

0

High-throughput

0.585

High

1350080

SPP2B
Signal peptide peptidase-like 2B

2

0

High-throughput

0.576

High

1214916

WLS
Protein wntless homolog

2

0

Small-scale

0.559

High

685958

KRA59
Keratin-associated protein 5-9

2

2

High-throughput

0.553

High

1059746

KRA11
Keratin-associated protein 1-1

2

1

High-throughput

0.553

High

873794

CD151
CD151 antigen

1

1

High-throughput

0.536

High

1415422

TMED9
Transmembrane emp24 domain-containing protein 9

1

3

High-throughput

0.536

High

1446124

TMED5
Transmembrane emp24 domain-containing protein 5

1

4

High-throughput

0.536

High

1446125

TMED7
Transmembrane emp24 domain-containing protein 7

1

4

High-throughput

0.536

High

1446106

AT132
Polyamine-transporting ATPase 13A2

1

0

Small-scale

0.518

High

1446118

SEC63
Translocation protein SEC63 homolog

1

1

High-throughput

0.515

High

182786

GP182
G-protein coupled receptor 182

1

0

High-throughput

0.513

High

226372

SNG1
Synaptogyrin-1

1

0

High-throughput

0.513

High

230208

S28A2
Sodium/nucleoside cotransporter 2

1

0

High-throughput

0.513

High

329016

RTN3
Reticulon-3

1

0

High-throughput

0.513

High

705995

CD1B
T-cell surface glycoprotein CD1b

1

0

High-throughput

0.513

High

833075

OX2G
OX-2 membrane glycoprotein

1

0

High-throughput

0.513

High

1064186

ADCY2
Adenylate cyclase type 2

1

0

High-throughput

0.513

High

1200252

T4S20
Transmembrane 4 L6 family member 20

1

0

High-throughput

0.513

High

1228407

SE1L3
Protein sel-1 homolog 3

1

0

High-throughput

0.513

High

1322529

D106A
Beta-defensin 106

1

0

High-throughput

0.513

High

1381349

NCLN
BOS complex subunit NCLN

1

0

High-throughput

0.513

High

1382208

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

1395867

CLP1L
Lipid scramblase CLPTM1L

1

0

High-throughput

0.513

High

1446113

TM140
Transmembrane protein 140

1

0

High-throughput

0.513

High

1446120

CC018
Uncharacterized protein C3orf18

1

0

High-throughput

0.513

High

1446122

CAH14
Carbonic anhydrase 14

1

0

High-throughput

0.513

High

1446128

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

0

High-throughput

0.513

High

252723

TSN3
Tetraspanin-3

1

1

High-throughput

0.489

High

835397

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

1

High-throughput

0.489

High

855287

GPR6
G-protein coupled receptor 6

1

1

High-throughput

0.489

High

1339950

OR4N2
Olfactory receptor 4N2

1

1

High-throughput

0.489

High

1369705

KLK6
Kallikrein-6

1

1

High-throughput

0.489

High

1438458

LPAR2
Lysophosphatidic acid receptor 2

1

1

High-throughput

0.489

High

846099

GLP1R
Glucagon-like peptide 1 receptor

1

1

Small-scale

0.481

High

48810

ESYT2
Extended synaptotagmin-2

1

1

High-throughput

0.479

High

466476

RHOC
Rho-related GTP-binding protein RhoC

1

5

High-throughput

0.479

High

535566

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.479

High

581308

RAC2
Ras-related C3 botulinum toxin substrate 2

1

5

High-throughput

0.479

High

953692

RAC3
Ras-related C3 botulinum toxin substrate 3

1

5

High-throughput

0.479

High

955633

CDC42
Cell division control protein 42 homolog

1

5

High-throughput

0.479

High

962521

RHOA
Transforming protein RhoA

1

6

High-throughput

0.479

High

1015818

RHOG
Rho-related GTP-binding protein RhoG

1

5

High-throughput

0.479

High

1098484

DNJC3
DnaJ homolog subfamily C member 3

1

1

High-throughput

0.479

High

1395955

DNJC1
DnaJ homolog subfamily C member 1

1

3

High-throughput

0.479

High

1412680

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.479

High

1431257

DJC25
DnaJ homolog subfamily C member 25

1

3

High-throughput

0.479

High

1446123

DJC16
DnaJ homolog subfamily C member 16

1

2

High-throughput

0.479

High

517116

NT2NC
Notch homolog 2 N-terminal-like protein C

1

1

High-throughput

0.470

High

1232591

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.470

High

174108

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.458

High

178408

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

246315

MARH6
E3 ubiquitin-protein ligase MARCHF6

1

0

High-throughput

0.458

High

375981

RASK
GTPase KRas

1

0

High-throughput

0.458

High

390776

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.458

High

417776

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

418451

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

537950

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

540694

LAMP1
Lysosome-associated membrane glycoprotein 1

1

0

High-throughput

0.458

High

820757

CEAM6
Cell adhesion molecule CEACAM6

1

0

High-throughput

0.458

High

828975

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

904137

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

944372

NAC3
Sodium/calcium exchanger 3

1

0

High-throughput

0.458

High

951451

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.458

High

1114371

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1248508

C16L2
CD164 sialomucin-like 2 protein

1

0

High-throughput

0.458

High

1249233

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1294266

GOLI
E3 ubiquitin-protein ligase RNF130

1

0

High-throughput

0.458

High

1327001

DJC22
DnaJ homolog subfamily C member 22

1

0

High-throughput

0.458

High

1337681

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.458

High

1352376

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.458

High

1383096

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

1404228

SEC62
Translocation protein SEC62

1

0

High-throughput

0.458

High

1414465

DERL1
Derlin-1

1

0

High-throughput

0.458

High

1436323

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

1439350

SDF2L
Stromal cell-derived factor 2-like protein 1

1

0

High-throughput

0.458

High

1446107

OR2S1
Olfactory receptor 2S2

1

0

High-throughput

0.458

High

1446108

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.458

High

1446109

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.458

High

1446115

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

1446116

DJB11
DnaJ homolog subfamily B member 11

1

0

High-throughput

0.458

High

1446127

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

1

0

High-throughput

0.458

High

1131624

MFS10
Major facilitator superfamily domain-containing protein 10

1

1

High-throughput

0.445

High

1365132

SL9A6
Sodium/hydrogen exchanger 6

1

1

High-throughput

0.445

High

1403634

SL9A7
Sodium/hydrogen exchanger 7

1

1

High-throughput

0.445

High

894185

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.439

High

1277417

NT2NA
Notch homolog 2 N-terminal-like protein A

1

1

High-throughput

0.439

High

1307459

KRA13
Keratin-associated protein 1-3

1

1

High-throughput

0.439

High

126818

RHOD
Rho-related GTP-binding protein RhoD

1

6

High-throughput

0.437

High

910213

RND2
Rho-related GTP-binding protein RhoN

1

6

High-throughput

0.437

High

1238829

TECT3
Tectonic-3

1

1

High-throughput

0.437

High

1392474

TECT2
Tectonic-2

1

1

High-throughput

0.437

High

1397173

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

1

High-throughput

0.437

High

933484

S12A2
Solute carrier family 12 member 2

1

0

High-throughput

0.426

High

1236333

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.426

High

1312992

S35F2
Solute carrier family 35 member F2

1

0

High-throughput

0.426

High

1346795

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

0

High-throughput

0.426

High

1348065

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

0

High-throughput

0.426

High

1356677

S22AH
Solute carrier family 22 member 17

1

1

High-throughput

0.407

High

1199705

KLH22
Kelch-like protein 22

4

0

High-throughput

0.358

High

566844

PDIA4
Protein disulfide-isomerase A4

2

0

High-throughput

0.319

High

70491

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

1257653

KRA52
Keratin-associated protein 5-2

2

0

High-throughput

0.316

High

869794

MTR1A
Melatonin receptor type 1A

1

0

High-throughput

0.282

High

378299

IFN21
Interferon alpha-21

1

0

High-throughput

0.279

Low

387563

APOA2
Apolipoprotein A-II

1

0

High-throughput

0.279

Low

515904

SAA1
Serum amyloid A-1 protein

1

0

High-throughput

0.279

Low

771820

SCN4A
Sodium channel protein type 4 subunit alpha

1

0

High-throughput

0.279

Low

925981

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

0

High-throughput

0.279

Low

927559

ATX1
Ataxin-1

1

0

High-throughput

0.279

Low

1040978

GNA12
Guanine nucleotide-binding protein subunit alpha-12

1

0

High-throughput

0.279

Low

1185902

TMM95
Sperm-egg fusion protein TMEM95

1

0

High-throughput

0.279

Low

1192294

ZACN
Ligand-gated cation channel ZACN

1

0

High-throughput

0.279

Low

1206608

PLAC9
Placenta-specific protein 9

1

0

High-throughput

0.279

Low

1286714

PP4P1
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

0

High-throughput

0.279

Low

1350760

SG1C1
Secretoglobin family 1C member 1

1

0

High-throughput

0.279

Low

1412312

TMM79
Transmembrane protein 79

1

0

High-throughput

0.279

Low

1446119

UBQL2
Ubiquilin-2

1

0

High-throughput

0.279

Low

1372311

H2B1H
Histone H2B type 1-H

1

0

High-throughput

0.269

Low

636

NBPFJ
NBPF family member NBPF19

1

0

High-throughput

0.251

Low

218812

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

401534

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.249

Low

464062

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

0

High-throughput

0.249

Low

589764

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

611367

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.249

Low

696582

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

769251

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

901594

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.249

Low

931456

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

1

0

High-throughput

0.249

Low

1248841

ENPP6
Glycerophosphocholine cholinephosphodiesterase ENPP6

1

0

High-throughput

0.249

Low

1255654

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1293167

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1382950

S2546
Mitochondrial outer membrane protein SLC25A46

1

0

High-throughput

0.249

Low

1403795

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.249

Low

1433964

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1446111

T106B
Transmembrane protein 106B

1

0

High-throughput

0.249

Low

1446112

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

1446117

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

303290

S22A5
Organic cation/carnitine transporter 2

1

0

High-throughput

0.232

Low

754108

CD80
T-lymphocyte activation antigen CD80

1

0

High-throughput

0.232

Low

886139

CXCR3
C-X-C chemokine receptor type 3

1

0

High-throughput

0.232

Low

1090035

NTCP2
Ileal sodium/bile acid cotransporter

1

0

High-throughput

0.232

Low

1126007

LRC32
Transforming growth factor beta activator LRRC32

1

0

High-throughput

0.232

Low

1355933

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

1

0

High-throughput

0.232

Low

1387801

MUCL1
Mucin-like protein 1

1

0

High-throughput

0.232

Low

1435995

PACC1
Proton-activated chloride channel

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025