Protein: NMD3
60S ribosomal export protein NMD3 (Nonsense-mediated mRNA decay protein 3)

Gene: NMD3
Organism: Saccharomyces cerevisiae S288C
Interactions: 161
UniProt ID: P38861

Gene Ontology (top 5):
GO:0000055 - ribosomal large subunit export from nucleus
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

806151

LSG1
Large subunit GTPase 1

19

1

Small-scale

0.765

High

601042

RL8A
Large ribosomal subunit protein eL8A

8

1

Small-scale

0.744

High

806164

ARX1
Probable metalloprotease ARX1

29

0

Small-scale

0.735

High

798499

REI1
Cytoplasmic 60S subunit biogenesis factor REI1

6

2

Small-scale

0.729

High

806188

IF6
Eukaryotic translation initiation factor 6

6

1

Small-scale

0.727

High

806178

BUD20
Bud site selection protein 20

7

0

Small-scale

0.712

High

806160

PVH1
Tyrosine-protein phosphatase YVH1

7

0

Small-scale

0.709

High

427270

RLA0
Large ribosomal subunit protein uL10

4

2

Small-scale

0.694

High

806192

MEX67
mRNA export factor MEX67

6

0

Small-scale

0.690

High

410124

RL25
Large ribosomal subunit protein uL23

4

0

Small-scale

0.657

High

409728

RL24A
Large ribosomal subunit protein eL24A

3

1

Small-scale

0.656

High

684720

RL5
Large ribosomal subunit protein uL18

3

1

Small-scale

0.656

High

712565

RL8B
Large ribosomal subunit protein eL8B

3

1

Small-scale

0.656

High

721927

XPO1
Exportin-1

3

2

Small-scale

0.656

High

806139

RL10
Large ribosomal subunit protein uL16

4

0

Small-scale

0.648

High

514285

RL12B
Large ribosomal subunit protein uL11B

3

1

Small-scale

0.640

High

806175

REH1
Cytoplasmic 60S subunit biogenesis factor REH1

3

2

Small-scale

0.640

High

544826

SSB1
Ribosome-associated molecular chaperone SSB1

3

2

Small-scale

0.633

High

570011

RL3
Large ribosomal subunit protein uL3

3

0

Small-scale

0.628

High

806143

ALB1
Ribosome biogenesis protein ALB1

3

0

Small-scale

0.628

High

721610

RENT1
ATP-dependent helicase NAM7

3

0

Small-scale

0.615

High

806163

NOG1
Nucleolar GTP-binding protein 1

3

0

Small-scale

0.613

High

433202

RL17A
Large ribosomal subunit protein uL22A

2

1

High-throughput

0.611

High

750079

MRT4
Ribosome assembly factor MRT4

2

2

Small-scale

0.601

High

433634

RL26A
Large ribosomal subunit protein uL24A

2

1

High-throughput

0.584

High

513499

RL1A
Large ribosomal subunit protein uL1A

2

1

High-throughput

0.584

High

689029

RL16A
Large ribosomal subunit protein uL13A

2

1

High-throughput

0.584

High

806130

NUG1
Nuclear GTP-binding protein NUG1

2

1

Small-scale

0.584

High

531733

RL4A
Large ribosomal subunit protein uL4A

2

1

High-throughput

0.571

High

806133

SSB2
Ribosome-associated molecular chaperone SSB2

2

2

Small-scale

0.571

High

806155

JJJ1
J protein JJJ1

2

1

Small-scale

0.571

High

806177

RLP24
Ribosome biogenesis protein RLP24

2

1

Small-scale

0.571

High

511196

RL20B
Large ribosomal subunit protein eL20B

2

0

High-throughput

0.559

High

515254

RL35A
Large ribosomal subunit protein uL29A

2

0

Small-scale

0.559

High

758030

MTR2
mRNA transport regulator MTR2

2

0

Small-scale

0.559

High

806140

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.559

High

806153

PESC
Pescadillo homolog

2

0

High-throughput

0.559

High

806182

NOP53
Ribosome biogenesis protein NOP53

2

0

High-throughput

0.559

High

753362

RS3A1
Small ribosomal subunit protein eS1A

2

0

High-throughput

0.547

High

666183

MEK1
Meiosis-specific serine/threonine-protein kinase MEK1

1

0

High-throughput

0.513

High

702246

YJU2
Splicing factor YJU2

1

0

High-throughput

0.513

High

806124

RIX1
Pre-rRNA-processing protein RIX1

1

0

Small-scale

0.513

High

806138

NOP2
25S rRNA

1

0

High-throughput

0.513

High

806144

DPB11
DNA replication regulator DPB11

1

0

High-throughput

0.513

High

806179

DIA2
Protein DIA2

1

0

High-throughput

0.513

High

740657

CBS
Cystathionine beta-synthase

1

0

High-throughput

0.493

High

806158

NOP3
Serine/arginine

1

0

Small-scale

0.493

High

806185

RPN5
26S proteasome regulatory subunit RPN5

1

0

High-throughput

0.493

High

806165

YD132
Uncharacterized protein YDR132C

1

0

High-throughput

0.486

High

154166

RL36B
Large ribosomal subunit protein eL36B

1

1

High-throughput

0.479

High

359218

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

1

Small-scale

0.479

High

432838

RL9A
Large ribosomal subunit protein uL6A

1

1

High-throughput

0.479

High

433019

RL6B
Large ribosomal subunit protein eL6B

1

1

High-throughput

0.479

High

434160

RL36A
Large ribosomal subunit protein eL36A

1

1

High-throughput

0.479

High

436406

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

1

High-throughput

0.479

High

444512

DED1
ATP-dependent RNA helicase DED1

1

1

Small-scale

0.479

High

503387

RL11A
Large ribosomal subunit protein uL5A

1

1

High-throughput

0.479

High

503790

RL27A
Large ribosomal subunit protein eL27A

1

1

High-throughput

0.479

High

503915

RL27B
Large ribosomal subunit protein eL27B

1

1

High-throughput

0.479

High

509894

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

1

1

High-throughput

0.479

High

523902

HSP71
Heat shock protein SSA1

1

2

Small-scale

0.479

High

526661

HSP72
Heat shock protein SSA2

1

2

Small-scale

0.479

High

632796

DBP5
ATP-dependent RNA helicase DBP5

1

1

Small-scale

0.479

High

645730

HSP74
Heat shock protein SSA4

1

2

Small-scale

0.479

High

670689

SIS1
Protein SIS1

1

1

High-throughput

0.479

High

689210

RL16B
Large ribosomal subunit protein uL13B

1

1

High-throughput

0.479

High

739362

ZUO1
Zuotin

1

2

Small-scale

0.479

High

745080

AFG2
ATPase family gene 2 protein

1

1

High-throughput

0.479

High

781188

RL14A
Large ribosomal subunit protein eL14A

1

1

High-throughput

0.479

High

803389

RL14B
Large ribosomal subunit protein eL14B

1

1

High-throughput

0.479

High

806134

RL13B
Large ribosomal subunit protein eL13B

1

1

High-throughput

0.479

High

806137

RL34B
Large ribosomal subunit protein eL34B

1

3

High-throughput

0.479

High

806142

RL17B
Large ribosomal subunit protein uL22B

1

1

High-throughput

0.479

High

806146

RL37A
Large ribosomal subunit protein eL37A

1

1

High-throughput

0.479

High

806147

RL4B
Large ribosomal subunit protein uL4B

1

1

High-throughput

0.479

High

806148

RL9B
Large ribosomal subunit protein uL6B

1

1

High-throughput

0.479

High

806149

RL37B
Large ribosomal subunit protein eL37B

1

1

High-throughput

0.479

High

806152

RL26B
Large ribosomal subunit protein uL24B

1

1

High-throughput

0.479

High

806157

RL34A
Large ribosomal subunit protein eL34A

1

3

High-throughput

0.479

High

806161

RL6A
Large ribosomal subunit protein eL6A

1

1

High-throughput

0.479

High

806162

RL21A
Large ribosomal subunit protein eL21A

1

1

High-throughput

0.479

High

806170

VMS1
tRNA endonuclease VMS1

1

3

High-throughput

0.479

High

806189

RL21B
Large ribosomal subunit protein eL21B

1

1

High-throughput

0.479

High

806190

RL13A
Large ribosomal subunit protein eL13A

1

1

High-throughput

0.479

High

806191

RL11B
Large ribosomal subunit protein uL5B

1

1

High-throughput

0.479

High

762816

TOR1
Serine/threonine-protein kinase TOR1

1

0

High-throughput

0.460

High

806123

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

High-throughput

0.460

High

149756

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

383695

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

392712

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.458

High

432575

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.458

High

434018

RL33A
Large ribosomal subunit protein eL33A

1

0

High-throughput

0.458

High

434250

RL29
Large ribosomal subunit protein eL29

1

0

High-throughput

0.458

High

434371

RL15A
Large ribosomal subunit protein eL15A

1

0

High-throughput

0.458

High

434565

RL22A
Large ribosomal subunit protein eL22A

1

0

High-throughput

0.458

High

435081

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

435957

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

455056

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

504205

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.458

High

510474

HSP77
Import motor subunit, mitochondrial

1

0

Small-scale

0.458

High

511418

RL43B
Large ribosomal subunit protein eL43B

1

0

High-throughput

0.458

High

511566

RL44B
Large ribosomal subunit protein eL42B

1

0

High-throughput

0.458

High

512433

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

513363

RL23B
Large ribosomal subunit protein uL14B

1

0

Small-scale

0.458

High

513683

RL2A
Large ribosomal subunit protein uL2A

1

0

High-throughput

0.458

High

515098

RL19B
Large ribosomal subunit protein eL19

1

0

High-throughput

0.458

High

515366

RS32B
Small ribosomal subunit protein eS32B

1

0

High-throughput

0.458

High

558714

CAF20
Cap-associated protein CAF20

1

0

Small-scale

0.458

High

560237

TOP3
DNA topoisomerase 3

1

0

High-throughput

0.458

High

569782

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.458

High

647103

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.458

High

666453

DBP2
ATP-dependent RNA helicase DBP2

1

0

High-throughput

0.458

High

674616

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

707057

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

727013

HS104
Heat shock protein 104

1

0

High-throughput

0.458

High

734971

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

747353

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

747843

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

776569

DEF1
RNA polymerase II degradation factor 1

1

0

High-throughput

0.458

High

778323

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

782251

SUMT
Uroporphyrinogen-III C-methyltransferase

1

0

Small-scale

0.458

High

792037

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.458

High

792516

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.458

High

798212

ENP1
Essential nuclear protein 1

1

0

High-throughput

0.458

High

806122

NMD3
60S ribosomal export protein NMD3

1

0

Small-scale

0.458

High

806126

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

806127

ECM1
Shuttling pre-60S factor ECM1

1

0

High-throughput

0.458

High

806128

NOC2
Nucleolar complex protein 2

1

0

Small-scale

0.458

High

806129

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.458

High

806131

GLE2
mRNA export factor GLE2

1

0

Small-scale

0.458

High

806132

NSA2
Ribosome biogenesis protein NSA2

1

0

Small-scale

0.458

High

806145

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

806154

GIS2
Zinc finger protein GIS2

1

0

High-throughput

0.458

High

806156

H3
Histone H3

1

0

High-throughput

0.458

High

806159

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

806166

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

806167

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.458

High

806168

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

806169

RRP17
Ribosomal RNA-processing protein 17

1

0

High-throughput

0.458

High

806171

RRP5
rRNA biogenesis protein RRP5

1

0

High-throughput

0.458

High

806172

RQC1
Ribosome quality control complex subunit 1

1

0

High-throughput

0.458

High

806173

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

806174

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

806176

ISA1
Iron-sulfur assembly protein 1

1

0

High-throughput

0.458

High

806180

TMA16
Translation machinery-associated protein 16

1

0

High-throughput

0.458

High

806181

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

806183

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

806184

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

806187

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

514211

RL12A
Large ribosomal subunit protein uL11A

1

1

Small-scale

0.445

High

806186

DBP10
ATP-dependent RNA helicase DBP10

1

2

High-throughput

0.437

High

394544

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

756623

NIC96
Nucleoporin NIC96

1

0

Small-scale

0.426

High

806135

NUP82
Nucleoporin NUP82

1

0

Small-scale

0.426

High

806136

NU159
Nucleoporin NUP159

1

0

Small-scale

0.426

High

806141

NUP85
Nucleoporin NUP85

1

0

Small-scale

0.426

High

806125

TEM1
Protein TEM1

1

0

High-throughput

0.279

Low

597456

EF3A
Elongation factor 3A

1

0

Small-scale

0.249

Low

794979

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

806150

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025