Protein: GFPT2
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase 2) (Glutamine:fructose-6-phosphate amidotransferase 2) (GFAT 2) (GFAT2) (Hexosephosphate aminotransferase 2)

Gene: GFPT2
Organism: Homo sapiens
Interactions: 65
UniProt ID: O94808

Gene Ontology (top 5):
GO:0004360 - glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GO:0005829 - cytosol
GO:0006002 - fructose 6-phosphate metabolic process
GO:0006047 - UDP-N-acetylglucosamine metabolic process
GO:0006048 - UDP-N-acetylglucosamine biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

317448

GFPT1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1

3

10

High-throughput

0.855

High

317449

LRP1
Prolow-density lipoprotein receptor-related protein 1

2

1

High-throughput

0.628

High

317462

SIR6
NAD-dependent protein deacylase sirtuin-6

3

3

High-throughput

0.599

High

240336

PRKN
E3 ubiquitin-protein ligase parkin

2

5

High-throughput

0.584

High

317452

CUL3
Cullin-3

1

4

High-throughput

0.536

High

289297

FCN3
Ficolin-3

1

0

High-throughput

0.513

High

296754

ST1C4
Sulfotransferase 1C4

1

0

High-throughput

0.513

High

317433

S10A6
Protein S100-A6

1

0

High-throughput

0.513

High

317434

TBB5
Tubulin beta chain

1

0

High-throughput

0.513

High

317446

ALR
FAD-linked sulfhydryl oxidase ALR

1

0

High-throughput

0.513

High

317468

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

0

High-throughput

0.513

High

317471

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.513

High

317435

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

3

High-throughput

0.501

High

165875

FFAR1
Free fatty acid receptor 1

1

1

High-throughput

0.489

High

317442

APJ
Apelin receptor

1

1

High-throughput

0.489

High

317457

FIGL1
Fidgetin-like protein 1

1

7

High-throughput

0.489

High

317459

SV2A
Synaptic vesicle glycoprotein 2A

1

2

High-throughput

0.489

High

317467

OIT3
Oncoprotein-induced transcript 3 protein

1

1

High-throughput

0.489

High

317443

HNF1B
Hepatocyte nuclear factor 1-beta

1

0

High-throughput

0.479

High

317432

GCR
Glucocorticoid receptor

1

2

High-throughput

0.479

High

317439

RO52
E3 ubiquitin-protein ligase TRIM21

1

1

High-throughput

0.479

High

317450

EP300
Histone acetyltransferase p300

1

5

High-throughput

0.479

High

317454

TNIP1
TNFAIP3-interacting protein 1

1

2

High-throughput

0.479

High

317460

DCP2
m7GpppN-mRNA hydrolase

1

1

High-throughput

0.479

High

317469

FBXW7
F-box/WD repeat-containing protein 7

1

3

Small-scale

0.479

High

317445

MTR1A
Melatonin receptor type 1A

1

1

High-throughput

0.464

High

176111

PER2
Period circadian protein homolog 2

1

0

Small-scale

0.458

High

317436

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.445

High

317447

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

3

High-throughput

0.445

High

317463

SETD6
N-lysine methyltransferase SETD6

1

1

High-throughput

0.445

High

317453

CUL4A
Cullin-4A

1

4

High-throughput

0.437

High

317458

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

317478

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.437

High

317440

FPR1
fMet-Leu-Phe receptor

1

2

High-throughput

0.407

High

317441

ACKR3
Atypical chemokine receptor 3

1

1

High-throughput

0.407

High

317470

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

1

2

High-throughput

0.407

High

317474

TBA1C
Tubulin alpha-1C chain

1

1

High-throughput

0.407

High

317481

DKK3
Dickkopf-related protein 3

2

0

High-throughput

0.328

High

317485

ACOT9
Acyl-coenzyme A thioesterase 9, mitochondrial

2

0

High-throughput

0.328

High

317486

SALL2
Sal-like protein 2

2

0

High-throughput

0.328

High

317480

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.299

High

317472

CLIC6
Chloride intracellular channel protein 6

1

0

High-throughput

0.282

High

317431

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.279

Low

317437

ACYP2
Acylphosphatase-2

1

0

High-throughput

0.279

Low

317444

MAGA8
Melanoma-associated antigen 8

1

0

High-throughput

0.279

Low

317451

SLAF1
Signaling lymphocytic activation molecule

1

0

High-throughput

0.279

Low

317461

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

0

High-throughput

0.279

Low

317464

F174A
Membrane protein FAM174A

1

0

High-throughput

0.279

Low

317465

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

317477

CST9L
Cystatin-9-like

1

0

High-throughput

0.279

Low

317483

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

0

High-throughput

0.279

Low

60824

MBPHL
Myosin-binding protein H-like

1

0

High-throughput

0.249

Low

104987

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

317430

NDUAA
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

1

0

High-throughput

0.249

Low

317438

ARSA
Arylsulfatase A

1

0

High-throughput

0.249

Low

317455

SUSD4
Sushi domain-containing protein 4

1

0

High-throughput

0.249

Low

317473

GPHA2
Glycoprotein hormone alpha-2

1

0

High-throughput

0.249

Low

317476

DPEP2
Dipeptidase 2

1

0

High-throughput

0.249

Low

317479

SIAE
Sialate O-acetylesterase

1

0

High-throughput

0.249

Low

317482

XPO7
Exportin-7

1

0

High-throughput

0.249

Low

262192

SCN2B
Sodium channel regulatory subunit beta-2

1

0

High-throughput

0.232

Low

317456

FDX2
Ferredoxin-2, mitochondrial

1

0

High-throughput

0.232

Low

317466

HAVR2
Hepatitis A virus cellular receptor 2

1

0

High-throughput

0.232

Low

317475

CCM2
Cerebral cavernous malformations 2 protein

1

0

High-throughput

0.232

Low

317484

PDIP2
Polymerase delta-interacting protein 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025