Protein: RAP1B
Ras-related protein Rap-1b (EC 3.6.5.2) (GTP-binding protein smg p21B)

Gene: RAP1B
Organism: Homo sapiens
Interactions: 166
UniProt ID: P61224

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0003925 - G protein activity
GO:0005525 - GTP binding
GO:0005811 - lipid droplet
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

897929

RSLAA
Ras-like protein family member 10A

3

17

High-throughput

0.861

High

897883

GNDS
Ral guanine nucleotide dissociation stimulator

3

20

Small-scale

0.843

High

854082

GDS1
Rap1 GTPase-GDP dissociation stimulator 1

2

10

High-throughput

0.811

High

171541

RGL2
Ral guanine nucleotide dissociation stimulator-like 2

2

20

Small-scale

0.800

High

897932

RAB7B
Ras-related protein Rab-7b

1

19

High-throughput

0.698

High

362997

FINC
Fibronectin

1

12

High-throughput

0.691

High

636297

DNJB1
DnaJ homolog subfamily B member 1

1

5

High-throughput

0.691

High

897923

RIN3
Ras and Rab interactor 3

1

20

High-throughput

0.691

High

897964

RGL1
Ral guanine nucleotide dissociation stimulator-like 1

1

20

High-throughput

0.691

High

897924

PLPR1
Phospholipid phosphatase-related protein type 1

3

2

High-throughput

0.667

High

812872

RPGP1
Rap1 GTPase-activating protein 1

1

14

Small-scale

0.665

High

897926

RASF5
Ras association domain-containing protein 5

1

10

High-throughput

0.662

High

897895

CLM2
CMRF35-like molecule 2

1

0

High-throughput

0.656

High

674784

GRPR
Gastrin-releasing peptide receptor

2

6

High-throughput

0.628

High

897953

PACC1
Proton-activated chloride channel

2

1

High-throughput

0.628

High

897913

ZDH17
Palmitoyltransferase ZDHHC17

1

20

High-throughput

0.625

High

897912

MYLK4
Myosin light chain kinase family member 4

1

7

High-throughput

0.618

High

897961

NRBP2
Nuclear receptor-binding protein 2

1

20

High-throughput

0.618

High

120375

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

313169

RPGF3
Rap guanine nucleotide exchange factor 3

1

20

Small-scale

0.618

High

373983

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

20

High-throughput

0.618

High

436236

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.618

High

542845

BRAF
Serine/threonine-protein kinase B-raf

1

20

High-throughput

0.618

High

545300

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

564467

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

591796

RAB4A
Ras-related protein Rab-4A

1

20

High-throughput

0.618

High

793250

MUC18
Cell surface glycoprotein MUC18

1

20

High-throughput

0.618

High

884464

RAB25
Ras-related protein Rab-25

1

19

High-throughput

0.618

High

892300

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

893855

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

897874

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

897876

RB11A
Ras-related protein Rab-11A

1

17

High-throughput

0.618

High

897877

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

897878

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

897884

PAK2
Serine/threonine-protein kinase PAK 2

1

20

High-throughput

0.618

High

897891

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.618

High

897938

M3K14
Mitogen-activated protein kinase kinase kinase 14

1

20

High-throughput

0.618

High

897952

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.618

High

897956

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

897959

ANLN
Anillin

1

8

High-throughput

0.618

High

897966

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.618

High

581599

VCAM1
Vascular cell adhesion protein 1

2

16

High-throughput

0.601

High

897925

NEK7
Serine/threonine-protein kinase Nek7

1

4

High-throughput

0.594

High

131823

KRIT1
Krev interaction trapped protein 1

1

20

Small-scale

0.575

High

897898

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

12

High-throughput

0.575

High

848533

CAV2
Caveolin-2

2

8

High-throughput

0.571

High

897896

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

20

High-throughput

0.553

High

897907

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.553

High

897976

PKHM1
Pleckstrin homology domain-containing family M member 1

1

7

Small-scale

0.553

High

897978

M3K4
Mitogen-activated protein kinase kinase kinase 4

1

3

High-throughput

0.553

High

782023

RGS2
Regulator of G-protein signaling 2

1

10

High-throughput

0.541

High

274980

RENR
Renin receptor

1

5

High-throughput

0.536

High

451226

TPM1
Tropomyosin alpha-1 chain

1

6

High-throughput

0.536

High

574288

RL35A
Large ribosomal subunit protein eL33

1

2

High-throughput

0.536

High

639923

ITB8
Integrin beta-8

1

19

High-throughput

0.536

High

686281

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

7

High-throughput

0.536

High

801050

KI67
Proliferation marker protein Ki-67

1

11

High-throughput

0.536

High

897901

SYT6
Synaptotagmin-6

1

9

High-throughput

0.536

High

897902

CDKAL
Threonylcarbamoyladenosine tRNA methylthiotransferase

1

3

High-throughput

0.536

High

897906

I20RB
Interleukin-20 receptor subunit beta

1

5

High-throughput

0.536

High

897909

DHB13
17-beta-hydroxysteroid dehydrogenase 13

1

11

High-throughput

0.536

High

897915

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

13

High-throughput

0.536

High

897922

UBP32
Ubiquitin carboxyl-terminal hydrolase 32

1

15

High-throughput

0.536

High

897930

STAM1
Signal transducing adapter molecule 1

1

12

High-throughput

0.536

High

897935

OPTN
Optineurin

1

20

High-throughput

0.536

High

897940

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

3

High-throughput

0.536

High

897942

TCAB1
Telomerase Cajal body protein 1

1

5

High-throughput

0.536

High

897947

DERL2
Derlin-2

1

1

High-throughput

0.536

High

897948

TOLIP
Toll-interacting protein

1

1

High-throughput

0.536

High

897960

CENPM
Centromere protein M

1

3

High-throughput

0.536

High

897967

LIMA1
LIM domain and actin-binding protein 1

1

20

High-throughput

0.536

High

897972

DICER
Endoribonuclease Dicer

1

1

High-throughput

0.536

High

897973

NTNG1
Netrin-G1

1

2

High-throughput

0.536

High

653541

CALR
Calreticulin

1

3

High-throughput

0.515

High

739050

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

6

High-throughput

0.515

High

111258

J3KNB8
Mitogen-activated protein kinase kinase kinase 4

1

12

High-throughput

0.514

High

441820

FGF4
Fibroblast growth factor 4

1

0

High-throughput

0.513

High

897900

UBR4
E3 ubiquitin-protein ligase UBR4

1

0

High-throughput

0.513

High

897903

ICE2
Little elongation complex subunit 2

1

0

High-throughput

0.513

High

897921

SEN2
tRNA-splicing endonuclease subunit Sen2

1

0

High-throughput

0.513

High

897934

T4S18
Transmembrane 4 L6 family member 18

1

0

High-throughput

0.513

High

897937

TECTB
Beta-tectorin

1

0

High-throughput

0.513

High

897950

MED28
Mediator of RNA polymerase II transcription subunit 28

1

0

High-throughput

0.513

High

897951

GHITM
Growth hormone-inducible transmembrane protein

1

0

High-throughput

0.513

High

897954

CB39L
Calcium-binding protein 39-like

1

0

High-throughput

0.513

High

897968

PADI3
Protein-arginine deiminase type-3

1

0

High-throughput

0.513

High

386421

P53
Cellular tumor antigen p53

1

2

High-throughput

0.508

High

526378

HEM1
5-aminolevulinate synthase, non-specific, mitochondrial

1

1

High-throughput

0.508

High

849920

APLP1
Amyloid beta precursor like protein 1

1

11

High-throughput

0.508

High

897881

TLE1
Transducin-like enhancer protein 1

1

5

High-throughput

0.508

High

897939

TCPH
T-complex protein 1 subunit eta

1

8

High-throughput

0.508

High

897941

CAB45
45 kDa calcium-binding protein

1

9

High-throughput

0.508

High

897971

FAF1
FAS-associated factor 1

1

13

High-throughput

0.508

High

394455

A4
Amyloid-beta precursor protein

1

11

High-throughput

0.501

High

897916

RPTOR
Regulatory-associated protein of mTOR

1

4

Small-scale

0.501

High

171745

WDR46
WD repeat-containing protein 46

1

5

High-throughput

0.489

High

198428

KLK10
Kallikrein-10

1

6

High-throughput

0.489

High

657994

ACADL
Long-chain specific acyl-CoA dehydrogenase, mitochondrial

1

3

High-throughput

0.489

High

897894

RTN1
Reticulon-1

1

12

High-throughput

0.489

High

897897

SYAM
Alanine--tRNA ligase, mitochondrial

1

1

High-throughput

0.489

High

897905

SHSA2
Protein shisa-2 homolog

1

2

High-throughput

0.489

High

897955

MAGF1
Melanoma-associated antigen F1

1

2

High-throughput

0.489

High

897957

NCK5L
Nck-associated protein 5-like

1

2

High-throughput

0.489

High

897974

AP3M1
AP-3 complex subunit mu-1

1

9

High-throughput

0.489

High

897975

DMXL1
DmX-like protein 1

1

7

High-throughput

0.489

High

326918

DDAH2
Putative hydrolase DDAH2

1

0

High-throughput

0.486

High

344472

A2MG
Alpha-2-macroglobulin

1

0

High-throughput

0.486

High

537861

KPYM
Pyruvate kinase PKM

1

0

High-throughput

0.486

High

897886

U119A
Protein unc-119 homolog A

1

0

High-throughput

0.486

High

227040

PRKN
E3 ubiquitin-protein ligase parkin

1

13

High-throughput

0.479

High

301714

TRI37
E3 ubiquitin-protein ligase TRIM37

1

12

High-throughput

0.479

High

503804

HSP7C
Heat shock cognate 71 kDa protein

1

7

High-throughput

0.479

High

523641

XRCC6
X-ray repair cross-complementing protein 6

1

3

High-throughput

0.479

High

530555

ITA4
Integrin alpha-4

1

20

High-throughput

0.479

High

617499

CRCM
Colorectal mutant cancer protein

1

5

High-throughput

0.479

High

827896

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

7

High-throughput

0.479

High

882207

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

16

High-throughput

0.479

High

897875

ARF6
ADP-ribosylation factor 6

1

18

High-throughput

0.479

High

897880

VIGLN
Vigilin

1

7

High-throughput

0.479

High

897882

KLC1
Kinesin light chain 1

1

7

High-throughput

0.479

High

897887

BIRC3
Baculoviral IAP repeat-containing protein 3

1

9

High-throughput

0.479

High

897888

CUL4A
Cullin-4A

1

8

High-throughput

0.479

High

897911

PAQR2
Adiponectin receptor protein 2

1

2

Small-scale

0.479

High

897917

EMC5
ER membrane protein complex subunit 5

1

4

High-throughput

0.479

High

897920

RN149
E3 ubiquitin-protein ligase RNF149

1

12

High-throughput

0.479

High

897927

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

4

High-throughput

0.479

High

897943

FACD2
Fanconi anemia group D2 protein

1

15

High-throughput

0.479

High

897944

ACE2
Angiotensin-converting enzyme 2

1

4

High-throughput

0.479

High

897945

TRI31
E3 ubiquitin-protein ligase TRIM31

1

3

High-throughput

0.479

High

897965

HDAC6
Histone deacetylase 6

1

9

High-throughput

0.479

High

897969

FZR1
Fizzy-related protein homolog

1

4

High-throughput

0.479

High

393778

SCG1
Secretogranin-1

1

2

High-throughput

0.464

High

897899

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

2

High-throughput

0.464

High

897970

KMT2B
Histone-lysine N-methyltransferase 2B

1

8

High-throughput

0.464

High

897977

CSAD
Cysteine sulfinic acid decarboxylase

1

3

High-throughput

0.464

High

496708

TAU
Microtubule-associated protein tau

1

16

High-throughput

0.445

High

897889

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

5

High-throughput

0.445

High

897919

CD177
CD177 antigen

1

4

Small-scale

0.445

High

897946

ZDHC5
Palmitoyltransferase ZDHHC5

1

20

High-throughput

0.445

High

552396

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.437

High

650844

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.437

High

720128

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.437

High

897885

TIF1B
Transcription intermediary factor 1-beta

1

6

High-throughput

0.437

High

897890

EMC2
ER membrane protein complex subunit 2

1

7

High-throughput

0.437

High

897892

EZH2
Histone-lysine N-methyltransferase EZH2

1

4

High-throughput

0.437

High

897893

E2F4
Transcription factor E2F4

1

3

High-throughput

0.437

High

897918

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

5

High-throughput

0.437

High

897928

ESR2
Estrogen receptor beta

1

18

High-throughput

0.437

High

897962

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

4

High-throughput

0.437

High

103890

G5E9S8
Kinesin light chain

1

6

High-throughput

0.407

High

874432

PLTP
Phospholipid transfer protein

2

0

High-throughput

0.318

High

238856

TPST2
Protein-tyrosine sulfotransferase 2

1

0

High-throughput

0.279

Low

579678

XRCC1
DNA repair protein XRCC1

1

0

High-throughput

0.279

Low

897879

RT35
Small ribosomal subunit protein mS35

1

0

High-throughput

0.279

Low

897914

CBCO1
Ciliary-associated calcium-binding coiled-coil protein 1

1

0

High-throughput

0.279

Low

897931

P33MX
Putative monooxygenase p33MONOX

1

0

High-throughput

0.279

Low

897936

EAF1
ELL-associated factor 1

1

0

High-throughput

0.279

Low

897949

PED1A
PC-esterase domain-containing protein 1A

1

0

High-throughput

0.279

Low

897958

NGRN
Neugrin

1

0

High-throughput

0.279

Low

897963

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

0

High-throughput

0.279

Low

897904

TPGS2
Tubulin polyglutamylase complex subunit 2

1

0

High-throughput

0.269

Low

897910

ZFHX4
Zinc finger homeobox protein 4

1

0

High-throughput

0.269

Low

505801

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

High-throughput

0.265

Low

855971

ZN135
Zinc finger protein 135

1

0

High-throughput

0.265

Low

897908

RD3
Protein RD3

1

0

High-throughput

0.249

Low

897933

PP14B
Protein phosphatase 1 regulatory subunit 14B

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024