Protein: LRC46
Leucine-rich repeat-containing protein 46

Gene: LRC46, LRRC46
Organism: Homo sapiens
Interactions: 49
UniProt ID: Q96FV0

Gene Ontology (top 5):
GO:0007283 - spermatogenesis
GO:0007288 - sperm axoneme assembly
GO:0007338 - single fertilization
GO:0097225 - sperm midpiece
GO:0098727 - maintenance of cell number

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

714645

TYK2
Non-receptor tyrosine-protein kinase TYK2

4

20

High-throughput

0.797

High

628830

TBP
TATA-box-binding protein

4

1

High-throughput

0.691

High

643387

OSBP1
Oxysterol-binding protein 1

4

2

High-throughput

0.630

High

1060471

DPOE1
DNA polymerase epsilon catalytic subunit A

4

1

High-throughput

0.630

High

1248434

LRSM1
E3 ubiquitin-protein ligase LRSAM1

4

20

High-throughput

0.630

High

1325070

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

4

1

High-throughput

0.630

High

1390924

FZR1
Fizzy-related protein homolog

4

3

High-throughput

0.630

High

935944

ECHB
Trifunctional enzyme subunit beta, mitochondrial

3

1

High-throughput

0.609

High

1291033

PACS2
Phosphofurin acidic cluster sorting protein 2

3

1

High-throughput

0.609

High

1356560

CCD12
Coiled-coil domain-containing protein 12

3

1

High-throughput

0.609

High

1390926

WDR37
WD repeat-containing protein 37

3

4

High-throughput

0.609

High

1292033

AMZ2
Archaemetzincin-2

3

1

High-throughput

0.593

High

272381

OBSL1
Obscurin-like protein 1

1

12

High-throughput

0.514

High

920187

PLK1
Serine/threonine-protein kinase PLK1

1

12

High-throughput

0.514

High

1160824

MAPK3
MAP kinase-activated protein kinase 3

1

4

High-throughput

0.514

High

1350803

RS4Y2
Small ribosomal subunit protein eS4, Y isoform 2

1

3

High-throughput

0.489

High

788326

GPX4
Phospholipid hydroperoxide glutathione peroxidase GPX4

1

2

High-throughput

0.445

High

76564

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

8

High-throughput

0.437

High

977332

RS4X
Small ribosomal subunit protein eS4, X isoform

1

3

High-throughput

0.437

High

289801

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

1

1

High-throughput

0.407

High

326972

UBE4B
Ubiquitin conjugation factor E4 B

1

1

High-throughput

0.407

High

931579

RD23A
UV excision repair protein RAD23 homolog A

1

2

High-throughput

0.407

High

1178863

CF184
Cilia- and flagella-associated protein 184

1

1

High-throughput

0.407

High

1247585

TBPL2
TATA box-binding protein-like 2

1

1

High-throughput

0.407

High

1358645

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

1

1

High-throughput

0.407

High

1371596

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

7

High-throughput

0.407

High

1390919

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

1

5

High-throughput

0.407

High

1390922

UTP6
U3 small nucleolar RNA-associated protein 6 homolog

1

4

High-throughput

0.407

High

1390925

MYO6
Unconventional myosin-VI

1

6

High-throughput

0.407

High

1390928

HBS1L
HBS1-like protein

1

3

High-throughput

0.407

High

1390930

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

3

High-throughput

0.407

High

503644

TFPT
TCF3 fusion partner

4

0

High-throughput

0.360

High

940496

DPOE2
DNA polymerase epsilon subunit 2

4

0

High-throughput

0.360

High

1335447

HJURP
Holliday junction recognition protein

4

0

High-throughput

0.360

High

1390918

PITX2
Pituitary homeobox 2

3

0

High-throughput

0.347

High

1390920

UQCC1
Ubiquinol-cytochrome c reductase complex assembly factor 1

3

0

High-throughput

0.347

High

1390921

DJC28
DnaJ homolog subfamily C member 28

3

0

High-throughput

0.347

High

1390923

SIX4
Homeobox protein SIX4

3

0

High-throughput

0.347

High

1390927

RRP7A
Ribosomal RNA-processing protein 7 homolog A

3

0

High-throughput

0.347

High

1334353

IN80E
INO80 complex subunit E

3

0

High-throughput

0.339

High

716132

AL4A1
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1390916

S35A4
Probable UDP-sugar transporter protein SLC35A4

1

0

High-throughput

0.269

Low

229152

GTPB6
Putative GTP-binding protein 6

1

0

High-throughput

0.232

Low

954576

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.232

Low

1126339

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.232

Low

1251628

KAT3
Kynurenine--oxoglutarate transaminase 3

1

0

High-throughput

0.232

Low

1390917

AEDO
2-aminoethanethiol dioxygenase

1

0

High-throughput

0.232

Low

1390929

TCAF1
TRPM8 channel-associated factor 1

1

0

High-throughput

0.232

Low

1390931

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025