Protein: HOOK1
Protein Hook homolog 1 (h-hook1) (hHK1)

Gene: HOOK1
Organism: Homo sapiens
Interactions: 229
UniProt ID: Q9UJC3

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005874 - microtubule
GO:0007030 - Golgi organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1202479

HOOK3
Protein Hook homolog 3

7

17

Small-scale

0.969

High

1355972

HOOK1
Protein Hook homolog 1

6

17

Small-scale

0.945

High

1333728

AKTIP
AKT-interacting protein

11

4

Small-scale

0.760

High

515529

CDK4
Cyclin-dependent kinase 4

5

12

High-throughput

0.726

High

1353884

TFP11
Tuftelin-interacting protein 11

5

1

High-throughput

0.718

High

1289575

HOOK2
Protein Hook homolog 2

1

18

Small-scale

0.713

High

1235427

FHI1B
FHF complex subunit HOOK-interacting protein 1B

4

13

Small-scale

0.697

High

1303832

CDC5L
Cell division cycle 5-like protein

4

1

High-throughput

0.688

High

1355979

TN13B
Tumor necrosis factor ligand superfamily member 13B

3

2

High-throughput

0.667

High

1023014

CDC16
Cell division cycle protein 16 homolog

2

2

High-throughput

0.628

High

1312178

AASD1
Alanyl-tRNA editing protein Aarsd1

2

1

High-throughput

0.628

High

1355981

CRYL1
Lambda-crystallin homolog

2

1

High-throughput

0.628

High

985765

FHI1A
FHF complex subunit HOOK-interacting protein 1A

2

13

High-throughput

0.621

High

638421

RBTN2
Rhombotin-2

3

5

High-throughput

0.616

High

230531

TRAK2
Trafficking kinesin-binding protein 2

2

17

High-throughput

0.611

High

320054

HERC2
E3 ubiquitin-protein ligase HERC2

2

7

High-throughput

0.611

High

863138

PGTB2
Geranylgeranyl transferase type-2 subunit beta

3

2

High-throughput

0.609

High

1107956

F161A
Protein FAM161A

2

4

High-throughput

0.606

High

1236859

ZN655
Zinc finger protein 655

2

2

High-throughput

0.606

High

1028291

SBP1
Methanethiol oxidase

2

0

High-throughput

0.602

High

1229582

SYCE1
Synaptonemal complex central element protein 1

2

2

High-throughput

0.588

High

231757

KIF1B
Kinesin-like protein KIF1B

2

13

High-throughput

0.584

High

1033353

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

2

6

High-throughput

0.584

High

1132270

CF141
Uncharacterized protein C6orf141

2

1

High-throughput

0.574

High

1152404

CNDH2
Condensin-2 complex subunit H2

2

1

High-throughput

0.574

High

271213

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

17

High-throughput

0.573

High

1201252

FHI2B
FHF complex subunit HOOK-interacting protein 2B

2

13

High-throughput

0.567

High

1286556

ENTR1
Endosome-associated-trafficking regulator 1

2

0

High-throughput

0.559

High

1355977

AP4E1
AP-4 complex subunit epsilon-1

2

7

Small-scale

0.558

High

1355988

AP4B1
AP-4 complex subunit beta-1

2

5

Small-scale

0.558

High

278349

PIAS2
E3 SUMO-protein ligase PIAS2

2

2

High-throughput

0.553

High

532332

ZNF35
Zinc finger protein 35

2

3

High-throughput

0.553

High

846614

ZNF80
Zinc finger protein 80

2

4

High-throughput

0.553

High

1103276

C19L2
CWF19-like protein 2

2

2

High-throughput

0.553

High

1135799

UT14C
U3 small nucleolar RNA-associated protein 14 homolog C

2

4

High-throughput

0.553

High

1189199

ZN572
Zinc finger protein 572

2

4

High-throughput

0.553

High

1197635

ANR23
Ankyrin repeat domain-containing protein 23

2

12

High-throughput

0.553

High

1293121

ZN764
Zinc finger protein 764

2

4

High-throughput

0.553

High

1354649

ZBT47
Zinc finger and BTB domain-containing protein 47

2

7

High-throughput

0.553

High

119735

AP4M1
AP-4 complex subunit mu-1

2

8

Small-scale

0.548

High

69258

MI4GD
MIF4G domain-containing protein

1

2

High-throughput

0.536

High

365106

FRIL
Ferritin light chain

1

2

High-throughput

0.536

High

1077162

MARE1
Microtubule-associated protein RP/EB family member 1

1

4

High-throughput

0.536

High

1101791

CF184
Cilia- and flagella-associated protein 184

1

1

High-throughput

0.536

High

1284840

EFMT3
EEF1A lysine methyltransferase 3

1

9

High-throughput

0.536

High

1316227

DUS16
Dual specificity protein phosphatase 16

1

7

High-throughput

0.536

High

1318419

UBXN6
UBX domain-containing protein 6

1

2

High-throughput

0.536

High

200911

CTIF
CBP80/20-dependent translation initiation factor

2

2

High-throughput

0.533

High

1139940

FHI2A
FHF complex subunit HOOK interacting protein 2A

2

13

High-throughput

0.533

High

66712

ZN785
Zinc finger protein 785

1

4

High-throughput

0.523

High

396012

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.515

High

960341

CDK5
Cyclin-dependent kinase 5

1

15

High-throughput

0.515

High

277371

ST1C4
Sulfotransferase 1C4

1

0

High-throughput

0.513

High

1128377

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

0

High-throughput

0.513

High

549239

ZN250
Zinc finger protein 250

1

1

High-throughput

0.494

High

149934

RFXK
DNA-binding protein RFXANK

1

6

High-throughput

0.489

High

281079

KRT38
Keratin, type I cuticular Ha8

1

19

High-throughput

0.489

High

548270

FOSL1
Fos-related antigen 1

1

4

High-throughput

0.489

High

1031110

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

8

High-throughput

0.489

High

1032211

ITAD
Integrin alpha-D

1

5

High-throughput

0.489

High

1238127

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

18

High-throughput

0.489

High

1268412

RUBIC
Run domain Beclin-1-interacting and cysteine-rich domain-containing protein

1

1

High-throughput

0.489

High

1306173

NPAS1
Neuronal PAS domain-containing protein 1

1

9

High-throughput

0.489

High

1316996

LOXE3
Hydroperoxide isomerase ALOXE3

1

1

High-throughput

0.489

High

1349066

GPC5D
G-protein coupled receptor family C group 5 member D

1

2

High-throughput

0.489

High

838344

MEOX2
Homeobox protein MOX-2

1

5

High-throughput

0.481

High

1041255

CUL1
Cullin-1

1

12

High-throughput

0.481

High

1159374

DEN1B
DENN domain-containing protein 1B

1

3

High-throughput

0.481

High

1273526

KAT5
Histone acetyltransferase KAT5

1

2

High-throughput

0.481

High

121600

IKBE
NF-kappa-B inhibitor epsilon

1

10

High-throughput

0.479

High

196365

PJA2
E3 ubiquitin-protein ligase Praja-2

1

2

High-throughput

0.479

High

201988

WDR62
WD repeat-containing protein 62

1

6

High-throughput

0.479

High

216984

KIF1C
Kinesin-like protein KIF1C

1

13

High-throughput

0.479

High

229007

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

229894

KIF5C
Kinesin heavy chain isoform 5C

1

7

High-throughput

0.479

High

230284

SI1L3
Signal-induced proliferation-associated 1-like protein 3

1

7

High-throughput

0.479

High

296385

AL1A2
Retinal dehydrogenase 2

1

2

High-throughput

0.479

High

300977

HAUS5
HAUS augmin-like complex subunit 5

1

1

High-throughput

0.479

High

304384

UBR5
E3 ubiquitin-protein ligase UBR5

1

9

High-throughput

0.479

High

313904

SVIL
Supervillin

1

14

High-throughput

0.479

High

327722

ECD
Protein ecdysoneless homolog

1

1

High-throughput

0.479

High

339106

EGFR
Epidermal growth factor receptor

1

11

High-throughput

0.479

High

427693

ANXA2
Annexin A2

1

7

High-throughput

0.479

High

443873

VIME
Vimentin

1

5

High-throughput

0.479

High

506075

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

1

5

High-throughput

0.479

High

513644

PYC
Pyruvate carboxylase, mitochondrial

1

8

High-throughput

0.479

High

521675

ACE
Angiotensin-converting enzyme

1

4

High-throughput

0.479

High

573522

TCPA
T-complex protein 1 subunit alpha

1

2

High-throughput

0.479

High

587742

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

13

High-throughput

0.479

High

592566

RAB5A
Ras-related protein Rab-5A

1

6

High-throughput

0.479

High

702992

KINH
Kinesin-1 heavy chain

1

7

High-throughput

0.479

High

833173

VPS41
Vacuolar protein sorting-associated protein 41 homolog

1

8

Small-scale

0.479

High

840342

PEX5
Peroxisomal targeting signal 1 receptor

1

2

High-throughput

0.479

High

857244

CAZA1
F-actin-capping protein subunit alpha-1

1

9

High-throughput

0.479

High

876724

BRPF1
Peregrin

1

8

High-throughput

0.479

High

897149

ACTZ
Alpha-centractin

1

19

High-throughput

0.479

High

943535

TCPB
T-complex protein 1 subunit beta

1

3

High-throughput

0.479

High

957658

LRP2
Low-density lipoprotein receptor-related protein 2

1

2

High-throughput

0.479

High

978928

TF65
Transcription factor p65

1

5

High-throughput

0.479

High

982600

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

992402

KLC1
Kinesin light chain 1

1

5

High-throughput

0.479

High

1015875

WASC5
WASH complex subunit 5

1

1

High-throughput

0.479

High

1051504

DCTN1
Dynactin subunit 1

1

20

High-throughput

0.479

High

1051707

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

3

High-throughput

0.479

High

1068696

PLEC
Plectin

1

16

High-throughput

0.479

High

1075882

TRIPB
Thyroid receptor-interacting protein 11

1

17

High-throughput

0.479

High

1085537

MK06
Mitogen-activated protein kinase 6

1

13

High-throughput

0.479

High

1145085

WAC2A
WASH complex subunit 2A

1

2

High-throughput

0.479

High

1158659

C2D1A
Coiled-coil and C2 domain-containing protein 1A

1

3

High-throughput

0.479

High

1164728

C1TM
Monofunctional C1-tetrahydrofolate synthase, mitochondrial

1

3

High-throughput

0.479

High

1167836

DNMBP
Dynamin-binding protein

1

20

High-throughput

0.479

High

1173723

VP13C
Intermembrane lipid transfer protein VPS13C

1

2

High-throughput

0.479

High

1236011

ARFG2
ADP-ribosylation factor GTPase-activating protein 2

1

1

High-throughput

0.479

High

1244551

NUP43
Nucleoporin Nup43

1

11

High-throughput

0.479

High

1267229

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

8

High-throughput

0.479

High

1267776

HS105
Heat shock protein 105 kDa

1

7

High-throughput

0.479

High

1287118

HAUS1
HAUS augmin-like complex subunit 1

1

1

High-throughput

0.479

High

1295098

VPS39
Vam6/Vps39-like protein

1

18

Small-scale

0.479

High

1295920

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

1

19

High-throughput

0.479

High

1297076

IFT74
Intraflagellar transport protein 74 homolog

1

19

High-throughput

0.479

High

1299407

RBM14
RNA-binding protein 14

1

3

High-throughput

0.479

High

1306733

TCPH
T-complex protein 1 subunit eta

1

2

High-throughput

0.479

High

1314493

IFT27
Intraflagellar transport protein 27 homolog

1

13

High-throughput

0.479

High

1319024

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

9

High-throughput

0.479

High

1327451

KLC2
Kinesin light chain 2

1

5

High-throughput

0.479

High

1328762

RBNS5
Rabenosyn-5

1

8

High-throughput

0.479

High

1329134

VPS16
Vacuolar protein sorting-associated protein 16 homolog

1

2

Small-scale

0.479

High

1331574

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

1333234

IFT22
Intraflagellar transport protein 22 homolog

1

6

High-throughput

0.479

High

1336256

Q9HCK3
KIAA1569 protein

1

1

High-throughput

0.479

High

1344408

4ET
Eukaryotic translation initiation factor 4E transporter

1

1

High-throughput

0.479

High

1345608

KLC4
Kinesin light chain 4

1

5

High-throughput

0.479

High

1346909

PAPD1
Poly(A) RNA polymerase, mitochondrial

1

1

High-throughput

0.479

High

1348425

ABI2
Abl interactor 2

1

17

High-throughput

0.479

High

1349414

LRP1B
Low-density lipoprotein receptor-related protein 1B

1

5

High-throughput

0.479

High

1350049

VPS18
Vacuolar protein sorting-associated protein 18 homolog

1

6

Small-scale

0.479

High

1350170

BCCIP
BRCA2 and CDKN1A-interacting protein

1

1

High-throughput

0.479

High

1350312

SI1L2
Signal-induced proliferation-associated 1-like protein 2

1

5

High-throughput

0.479

High

1354482

AASS
Alpha-aminoadipic semialdehyde synthase, mitochondrial

1

1

High-throughput

0.479

High

1354664

RIM3A
RIMS-binding protein 3A

1

15

High-throughput

0.479

High

1354783

ZRAN1
Ubiquitin thioesterase ZRANB1

1

13

High-throughput

0.479

High

1355350

TBK1
Serine/threonine-protein kinase TBK1

1

19

High-throughput

0.479

High

1355973

TNIK
TRAF2 and NCK-interacting protein kinase

1

20

High-throughput

0.479

High

1355978

PZRN3
E3 ubiquitin-protein ligase PDZRN3

1

13

High-throughput

0.479

High

1355982

GIT1
ARF GTPase-activating protein GIT1

1

5

High-throughput

0.479

High

1355989

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

1

3

High-throughput

0.479

High

1086347

H31T
Histone H3.1t

1

7

High-throughput

0.470

High

261609

NCOR1
Nuclear receptor corepressor 1

1

18

High-throughput

0.470

High

1151291

Q6FHY5
MEOX2 protein

1

5

High-throughput

0.470

High

905771

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.460

High

1347094

RBM22
Pre-mRNA-splicing factor RBM22

1

0

High-throughput

0.460

High

47967

IFT56
Intraflagellar transport protein 56

1

0

High-throughput

0.458

High

875410

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

1101367

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1147757

HAUS3
HAUS augmin-like complex subunit 3

1

0

High-throughput

0.458

High

1222019

IFT20
Intraflagellar transport protein 20 homolog

1

0

High-throughput

0.458

High

1222166

DHX37
Probable ATP-dependent RNA helicase DHX37

1

0

High-throughput

0.458

High

1332246

HAUS4
HAUS augmin-like complex subunit 4

1

0

High-throughput

0.458

High

1343429

IFT46
Intraflagellar transport protein 46 homolog

1

0

High-throughput

0.458

High

1355976

SUFU
Suppressor of fused homolog

1

0

High-throughput

0.458

High

56768

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

4

High-throughput

0.445

High

1039922

SNW1
SNW domain-containing protein 1

1

2

High-throughput

0.439

High

1261907

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

1

3

High-throughput

0.439

High

1286124

LENG1
Leukocyte receptor cluster member 1

1

1

High-throughput

0.439

High

1313914

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

4

High-throughput

0.439

High

1315723

AP1M1
AP-1 complex subunit mu-1

1

8

Small-scale

0.439

High

149399

CTRO
Citron Rho-interacting kinase

1

18

High-throughput

0.437

High

167033

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

8

High-throughput

0.437

High

246293

NBN
Nibrin

1

1

High-throughput

0.437

High

398308

PCCA
Propionyl-CoA carboxylase alpha chain, mitochondrial

1

8

High-throughput

0.437

High

398418

PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial

1

5

High-throughput

0.437

High

444506

K1C19
Keratin, type I cytoskeletal 19

1

11

High-throughput

0.437

High

451751

CLCB
Clathrin light chain B

1

5

High-throughput

0.437

High

554006

RFA2
Replication protein A 32 kDa subunit

1

6

High-throughput

0.437

High

683020

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

2

High-throughput

0.437

High

721727

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

724398

FBN2
Fibrillin-2 [Cleaved into: Placensin]

1

3

High-throughput

0.437

High

726467

BASI
Basigin

1

4

Small-scale

0.437

High

823511

PAXI
Paxillin

1

14

High-throughput

0.437

High

891620

MYL6
Myosin light polypeptide 6

1

20

High-throughput

0.437

High

950573

ARF1
ADP-ribosylation factor 1

1

3

High-throughput

0.437

High

1024110

ACACA
Acetyl-CoA carboxylase 1

1

8

High-throughput

0.437

High

1072731

UBE3C
Ubiquitin-protein ligase E3C

1

8

High-throughput

0.437

High

1103101

ATG2A
Autophagy-related protein 2 homolog A

1

2

High-throughput

0.437

High

1124961

ZN326
DBIRD complex subunit ZNF326

1

1

High-throughput

0.437

High

1126059

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

3

High-throughput

0.437

High

1145645

F91A1
Protein FAM91A1

1

1

High-throughput

0.437

High

1148856

VIR
Protein virilizer homolog

1

2

High-throughput

0.437

High

1159463

FBX42
F-box only protein 42

1

12

High-throughput

0.437

High

1166052

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

1168434

LMTK1
Serine/threonine-protein kinase LMTK1

1

20

High-throughput

0.437

High

1174127

UBP54
Inactive ubiquitin carboxyl-terminal hydrolase 54

1

10

High-throughput

0.437

High

1238726

KRI1
Protein KRI1 homolog

1

1

High-throughput

0.437

High

1272054

RAD50
DNA repair protein RAD50

1

19

High-throughput

0.437

High

1290092

RNF31
E3 ubiquitin-protein ligase RNF31

1

12

High-throughput

0.437

High

1299875

LENG8
Leukocyte receptor cluster member 8

1

1

High-throughput

0.437

High

1301297

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

8

High-throughput

0.437

High

1310463

GPTC1
G patch domain-containing protein 1

1

1

High-throughput

0.437

High

1335933

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

5

High-throughput

0.437

High

1345174

VPS45
Vacuolar protein sorting-associated protein 45

1

6

High-throughput

0.437

High

1354499

ZO2
Tight junction protein ZO-2

1

9

High-throughput

0.437

High

1355974

RAB21
Ras-related protein Rab-21

1

10

High-throughput

0.437

High

1355975

MRTFB
Myocardin-related transcription factor B

1

7

High-throughput

0.437

High

1355986

FARP1
FERM, ARHGEF and pleckstrin domain-containing protein 1

1

10

High-throughput

0.437

High

1355987

HYOU1
Hypoxia up-regulated protein 1

1

7

High-throughput

0.437

High

1091187

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

4

High-throughput

0.407

High

1169920

PKHG7
Pleckstrin homology domain-containing family G member 7

1

18

High-throughput

0.407

High

1318886

ZDHC5
Palmitoyltransferase ZDHHC5

1

2

High-throughput

0.407

High

1349742

TBCD7
TBC1 domain family member 7

4

0

High-throughput

0.364

High

1291033

ZB10P
Putative protein ZBED10P

1

0

High-throughput

0.279

Low

300281

PRP6
Pre-mRNA-processing factor 6

1

0

High-throughput

0.251

Low

1063781

EXOS7
Exosome complex component RRP42

1

0

High-throughput

0.251

Low

1288173

ESS2
Splicing factor ESS-2 homolog

1

0

High-throughput

0.251

Low

1334391

UNKL
Putative E3 ubiquitin-protein ligase UNKL

1

0

High-throughput

0.251

Low

1355985

CCDC9
Coiled-coil domain-containing protein 9

1

0

High-throughput

0.251

Low

906943

PRS4
26S proteasome regulatory subunit 4

1

0

High-throughput

0.249

Low

974019

M2OM
Mitochondrial 2-oxoglutarate/malate carrier protein

1

0

High-throughput

0.249

Low

986447

P2R3A
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha

1

0

High-throughput

0.249

Low

1058717

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

0

High-throughput

0.249

Low

1127784

AMER1
APC membrane recruitment protein 1

1

0

High-throughput

0.249

Low

1200248

N4BP2
NEDD4-binding protein 2

1

0

High-throughput

0.249

Low

1218537

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.249

Low

1268565

K0232
Uncharacterized protein KIAA0232

1

0

High-throughput

0.249

Low

1316262

K1671
Uncharacterized protein KIAA1671

1

0

High-throughput

0.249

Low

1348895

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.249

Low

1355980

NCKP1
Nck-associated protein 1

1

0

High-throughput

0.249

Low

1355983

TMED5
Transmembrane emp24 domain-containing protein 5

1

0

High-throughput

0.249

Low

1355984

NOC2L
Nucleolar complex protein 2 homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024