Protein: GPKOW
G-patch domain and KOW motifs-containing protein (G-patch domain-containing protein 5) (Protein MOS2 homolog) (Protein T54)

Gene: GPKOW
Organism: Homo sapiens
Interactions: 124
UniProt ID: Q92917

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005681 - spliceosomal complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

238931

DHX16
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

5

3

Small-scale

0.938

High

1370623

BUD13
BUD13 homolog

8

2

High-throughput

0.755

High

976125

RPB7
DNA-directed RNA polymerase II subunit RPB7

2

0

High-throughput

0.742

High

1365835

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

3

High-throughput

0.740

High

1090833

TRAF2
TNF receptor-associated factor 2

4

3

High-throughput

0.698

High

1150144

TCEA2
Transcription elongation factor A protein 2

4

1

High-throughput

0.698

High

1370640

ZRAN1
Ubiquitin thioesterase ZRANB1

3

1

High-throughput

0.653

High

1370630

ROP1A
Ropporin-1A

3

0

High-throughput

0.646

High

386051

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

3

1

High-throughput

0.640

High

1370621

SH3G1
Endophilin-A2

4

1

High-throughput

0.629

High

654665

TCEA1
Transcription elongation factor A protein 1

2

1

High-throughput

0.606

High

1370634

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

2

0

High-throughput

0.605

High

783361

TRI23
E3 ubiquitin-protein ligase TRIM23

2

0

High-throughput

0.601

High

260257

BRD4
Bromodomain-containing protein 4

2

1

High-throughput

0.584

High

210324

PHF1
PHD finger protein 1

2

0

High-throughput

0.580

High

250308

VINEX
Vinexin

2

0

High-throughput

0.580

High

269328

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

572103

TRI27
Zinc finger protein RFP

2

0

High-throughput

0.580

High

1048948

REL
Proto-oncogene c-Rel

2

0

High-throughput

0.580

High

1205913

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

0

High-throughput

0.580

High

1370647

MD1L1
Mitotic spindle assembly checkpoint protein MAD1

2

0

High-throughput

0.580

High

1370648

NEMO
NF-kappa-B essential modulator

2

0

High-throughput

0.580

High

387866

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

2

1

High-throughput

0.574

High

209315

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

1

1

High-throughput

0.573

High

1370638

LR2BP
LRP2-binding protein

2

1

High-throughput

0.553

High

1370641

TRIM1
Probable E3 ubiquitin-protein ligase MID2

2

3

High-throughput

0.553

High

1023140

RBM10
RNA-binding protein 10

1

0

High-throughput

0.549

High

1241717

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.549

High

1370626

KLC2
Kinesin light chain 2

1

1

High-throughput

0.536

High

462547

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

1

High-throughput

0.515

High

1232500

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.515

High

50921

SYCE3
Synaptonemal complex central element protein 3

1

0

High-throughput

0.513

High

325026

HEXI1
Protein HEXIM1

1

0

High-throughput

0.513

High

603674

JUNB
Transcription factor JunB

1

0

High-throughput

0.513

High

931039

HSP72
Heat shock-related 70 kDa protein 2

1

0

High-throughput

0.513

High

1016360

SERF2
Small EDRK-rich factor 2

1

0

High-throughput

0.513

High

1334718

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.513

High

1370619

TREF1
Transcriptional-regulating factor 1

1

0

High-throughput

0.513

High

1370628

ASCC2
Activating signal cointegrator 1 complex subunit 2

1

0

High-throughput

0.513

High

1370633

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

High-throughput

0.513

High

1370622

MEP50
Methylosome protein WDR77

1

2

High-throughput

0.508

High

1370624

WDR83
WD repeat domain-containing protein 83

1

1

High-throughput

0.508

High

651695

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

2

Small-scale

0.506

High

908254

PRKX
cAMP-dependent protein kinase catalytic subunit PRKX

1

2

Small-scale

0.506

High

967896

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

0

High-throughput

0.486

High

894071

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.481

High

1361126

PIBF1
Progesterone-induced-blocking factor 1

1

1

High-throughput

0.481

High

185901

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.480

High

1370646

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

487603

PARP1
Poly [ADP-ribose] polymerase 1

1

2

High-throughput

0.479

High

589323

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

696118

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

714322

PML
Protein PML

1

1

High-throughput

0.479

High

998637

H31
Histone H3.1

1

1

High-throughput

0.479

High

1017079

H33
Histone H3.3

1

1

High-throughput

0.479

High

1096777

RFA4
Replication protein A 30 kDa subunit

1

1

High-throughput

0.479

High

1257093

PAXI1
PAX-interacting protein 1

1

1

High-throughput

0.479

High

1364190

TOPB1
DNA topoisomerase 2-binding protein 1

1

1

High-throughput

0.479

High

1370631

ANLN
Anillin

1

1

High-throughput

0.479

High

1194565

Q4G0R1
PIBF1 protein

1

1

High-throughput

0.470

High

1232348

Q6FGM0
Endophilin-A2

1

1

High-throughput

0.470

High

173165

XPO1
Exportin-1

1

0

High-throughput

0.458

High

242488

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

347854

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

401242

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

404290

GCR
Glucocorticoid receptor

1

0

High-throughput

0.458

High

558308

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

768807

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

951794

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

Small-scale

0.458

High

970875

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

980981

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

1027643

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

0

High-throughput

0.458

High

1097463

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.458

High

1156803

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

1276584

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1289509

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1313312

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1339639

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

1370612

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

1370620

CTIP
DNA endonuclease RBBP8

1

0

Small-scale

0.458

High

1370635

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1370639

HDAC6
Protein deacetylase HDAC6

1

0

High-throughput

0.458

High

1370642

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.458

High

605770

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

2

Small-scale

0.445

High

1322611

RPTOR
Regulatory-associated protein of mTOR

1

1

High-throughput

0.445

High

1370645

RBMX2
RNA-binding motif protein, X-linked 2

1

3

High-throughput

0.445

High

1227195

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.437

High

1254914

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

1370629

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

575178

IDE
Insulin-degrading enzyme

1

0

High-throughput

0.426

High

765765

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.426

High

1104629

IKZF1
DNA-binding protein Ikaros

1

0

High-throughput

0.426

High

1370625

INP5K
Inositol polyphosphate 5-phosphatase K

1

0

High-throughput

0.426

High

1063492

GOGA2
Golgin subfamily A member 2

4

0

High-throughput

0.364

High

1322709

F177A
Protein FAM177A1

3

0

High-throughput

0.347

High

66896

SPDE4
Speedy protein E4

2

0

High-throughput

0.316

High

725432

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

2

0

High-throughput

0.316

High

857055

GSTM5
Glutathione S-transferase Mu 5

2

0

High-throughput

0.316

High

1131209

MESD
LRP chaperone MESD

2

0

High-throughput

0.316

High

1206415

EFHC2
EF-hand domain-containing family member C2

2

0

High-throughput

0.316

High

1225033

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

0

High-throughput

0.316

High

1243426

CNKR3
Connector enhancer of kinase suppressor of ras 3

2

0

High-throughput

0.316

High

1323313

VPS52
Vacuolar protein sorting-associated protein 52 homolog

2

0

High-throughput

0.316

High

1348401

LNX1
E3 ubiquitin-protein ligase LNX

2

0

High-throughput

0.316

High

1370613

DDT4L
DNA damage-inducible transcript 4-like protein

2

0

High-throughput

0.316

High

1370615

HOOK2
Protein Hook homolog 2

2

0

High-throughput

0.316

High

1370617

GMPPA
Mannose-1-phosphate guanylyltransferase regulatory subunit alpha

2

0

High-throughput

0.316

High

1370627

ZMY12
Zinc finger MYND domain-containing protein 12

2

0

High-throughput

0.316

High

1370632

PICK1
PRKCA-binding protein

2

0

High-throughput

0.316

High

1370637

ARMX1
Armadillo repeat-containing X-linked protein 1

2

0

High-throughput

0.316

High

1370643

LZTS1
Leucine zipper putative tumor suppressor 1

2

0

High-throughput

0.316

High

1179998

CCD57
Coiled-coil domain-containing protein 57

1

0

High-throughput

0.299

High

1370644

NINL
Ninein-like protein

1

0

High-throughput

0.282

High

907682

CLCN2
Chloride channel protein 2

1

0

High-throughput

0.279

Low

1280206

MILR1
Allergin-1

1

0

High-throughput

0.279

Low

1370614

RMC1
Regulator of MON1-CCZ1 complex

1

0

High-throughput

0.279

Low

1370616

KBP
KIF-binding protein

1

0

High-throughput

0.279

Low

1370618

KAD7
Adenylate kinase 7

1

0

High-throughput

0.279

Low

1370636

PIM2
Serine/threonine-protein kinase pim-2

1

0

High-throughput

0.279

Low

422778

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.261

Low

377677

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

412382

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

995742

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.249

Low

1340183

ARK74
Aflatoxin B1 aldehyde reductase member 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025