Protein: ZN688
Zinc finger protein 688

Gene: ZN688, ZNF688
Organism: Homo sapiens
Interactions: 116
UniProt ID: P0C7X2

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

505771

NEK6
Serine/threonine-protein kinase Nek6

2

5

High-throughput

0.783

High

505712

MKRN3
E3 ubiquitin-protein ligase makorin-3

3

4

High-throughput

0.654

High

505774

ABI2
Abl interactor 2

3

5

High-throughput

0.654

High

505715

TIF1B
Transcription intermediary factor 1-beta

2

20

High-throughput

0.611

High

180215

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

2

1

High-throughput

0.606

High

210235

PHF1
PHD finger protein 1

2

1

High-throughput

0.606

High

505692

CCNC
Cyclin-C

2

1

High-throughput

0.606

High

505694

RBTN2
Rhombotin-2

2

15

High-throughput

0.606

High

505695

RBTN1
Rhombotin-1

2

15

High-throughput

0.606

High

505698

HXA1
Homeobox protein Hox-A1

2

15

High-throughput

0.606

High

505700

GEM
GTP-binding protein GEM

2

2

High-throughput

0.606

High

505701

CDN2D
Cyclin-dependent kinase 4 inhibitor D

2

12

High-throughput

0.606

High

505708

TLE5
TLE family member 5

2

2

High-throughput

0.606

High

505731

IGFN1
Immunoglobulin-like and fibronectin type III domain-containing protein 1

2

2

High-throughput

0.606

High

505738

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

2

3

High-throughput

0.606

High

505741

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

2

3

High-throughput

0.606

High

505752

TET5B
Terminal nucleotidyltransferase 5B

2

1

High-throughput

0.606

High

505764

SCNM1
Sodium channel modifier 1

2

5

High-throughput

0.606

High

505770

DEFI6
Differentially expressed in FDCP 6 homolog

2

1

High-throughput

0.606

High

505773

AIRIM
AFG2-interacting ribosome maturation factor

2

1

High-throughput

0.606

High

505784

ZN330
Zinc finger protein 330

2

7

High-throughput

0.606

High

505767

CARD9
Caspase recruitment domain-containing protein 9

3

10

High-throughput

0.597

High

505691

PSB1
Proteasome subunit beta type-1

2

0

High-throughput

0.580

High

505710

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

2

0

High-throughput

0.580

High

505748

TEKT4
Tektin-4

2

0

High-throughput

0.580

High

505781

NFU1
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial

2

0

High-throughput

0.580

High

222005

NCK2
Cytoplasmic protein NCK2

2

6

High-throughput

0.553

High

269146

HSF2B
Heat shock factor 2-binding protein

2

1

High-throughput

0.553

High

350430

GPAN1
G patch domain and ankyrin repeat-containing protein 1

2

7

High-throughput

0.553

High

505723

C102B
Coiled-coil domain-containing protein 102B

2

2

High-throughput

0.553

High

505725

TTC19
Tetratricopeptide repeat protein 19, mitochondrial

2

7

High-throughput

0.553

High

505732

CDR2L
Cerebellar degeneration-related protein 2-like

2

7

High-throughput

0.553

High

505735

GLCTK
Glycerate kinase

2

1

High-throughput

0.553

High

505744

CTSR1
Cation channel sperm-associated protein 1

2

1

High-throughput

0.553

High

505747

MYOZ3
Myozenin-3

2

1

High-throughput

0.553

High

505750

TCP11
T-complex protein 11 homolog

2

1

High-throughput

0.553

High

505758

CIB3
Calcium and integrin-binding family member 3

2

6

High-throughput

0.553

High

505776

RCOR3
REST corepressor 3

2

4

High-throughput

0.553

High

505697

CBX5
Chromobox protein homolog 5

1

20

Small-scale

0.536

High

505778

TF3C4
General transcription factor 3C polypeptide 4

1

3

High-throughput

0.536

High

505783

FBX7
F-box only protein 7

1

2

High-throughput

0.501

High

131687

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

2

High-throughput

0.481

High

180472

PLS1
Phospholipid scramblase 1

1

3

High-throughput

0.481

High

209941

CRX
Cone-rod homeobox protein

1

6

High-throughput

0.481

High

283424

TAD2A
Transcriptional adapter 2-alpha

1

1

High-throughput

0.481

High

284646

KHDR3
KH domain-containing, RNA-binding, signal transduction-associated protein 3

1

3

High-throughput

0.481

High

343727

LDOC1
Protein LDOC1

1

6

High-throughput

0.481

High

505686

K1C13
Keratin, type I cytoskeletal 13

1

12

High-throughput

0.481

High

505687

TRI27
Zinc finger protein RFP

1

20

High-throughput

0.481

High

505688

ITF2
Transcription factor 4

1

5

High-throughput

0.481

High

505690

K1C15
Keratin, type I cytoskeletal 15

1

12

High-throughput

0.481

High

505693

PSA3
Proteasome subunit alpha type-3

1

1

High-throughput

0.481

High

505696

TRI23
E3 ubiquitin-protein ligase TRIM23

1

4

High-throughput

0.481

High

505699

MEOX2
Homeobox protein MOX-2

1

14

High-throughput

0.481

High

505706

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

1

High-throughput

0.481

High

505707

REL
Proto-oncogene c-Rel

1

4

High-throughput

0.481

High

505711

TRAF2
TNF receptor-associated factor 2

1

20

High-throughput

0.481

High

505713

TRAF1
TNF receptor-associated factor 1

1

15

High-throughput

0.481

High

505714

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

4

High-throughput

0.481

High

505718

TRIP6
Thyroid receptor-interacting protein 6

1

3

High-throughput

0.481

High

505720

FHL5
Four and a half LIM domains protein 5

1

15

High-throughput

0.481

High

505721

KHDR2
KH domain-containing, RNA-binding, signal transduction-associated protein 2

1

3

High-throughput

0.481

High

505722

TENS2
Tensin-2

1

2

High-throughput

0.481

High

505726

HMBX1
Homeobox-containing protein 1

1

5

High-throughput

0.481

High

505728

ANR11
Ankyrin repeat domain-containing protein 11

1

6

High-throughput

0.481

High

505729

BEND5
BEN domain-containing protein 5

1

1

High-throughput

0.481

High

505734

RFX6
DNA-binding protein RFX6

1

1

High-throughput

0.481

High

505736

HOMEZ
Homeobox and leucine zipper protein Homez

1

5

High-throughput

0.481

High

505746

MIPO1
Mirror-image polydactyly gene 1 protein

1

1

High-throughput

0.481

High

505753

GASP2
G-protein coupled receptor-associated sorting protein 2

1

1

High-throughput

0.481

High

505757

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

16

High-throughput

0.481

High

505760

HTF4
Transcription factor 12

1

5

High-throughput

0.481

High

505761

MDFI
MyoD family inhibitor

1

9

High-throughput

0.481

High

505762

TRAF4
TNF receptor-associated factor 4

1

20

High-throughput

0.481

High

505768

GO45
Golgin-45

1

2

High-throughput

0.481

High

505769

BOLA2
BolA-like protein 2

1

1

High-throughput

0.481

High

505772

ZC4H2
Zinc finger C4H2 domain-containing protein

1

3

High-throughput

0.481

High

505777

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

20

High-throughput

0.481

High

505782

ADIP
Afadin- and alpha-actinin-binding protein

1

6

High-throughput

0.481

High

505785

MAGD1
Melanoma-associated antigen D1

1

6

High-throughput

0.481

High

505716

CUL3
Cullin-3

1

20

High-throughput

0.479

High

753

A0A087WZT3
BOLA2-SMG1P6 readthrough

1

1

High-throughput

0.470

High

505786

X5D778
Ankyrin repeat domain 11 isoform A

1

14

High-throughput

0.470

High

155646

FCHO1
F-BAR domain only protein 1

1

3

High-throughput

0.439

High

220734

PPIP1
Proline-serine-threonine phosphatase-interacting protein 1

1

3

High-throughput

0.439

High

270083

TMCC2
Transmembrane and coiled-coil domains protein 2

1

1

High-throughput

0.439

High

505702

KR122
Keratin-associated protein 12-2

1

20

High-throughput

0.439

High

505703

KR103
Keratin-associated protein 10-3

1

20

High-throughput

0.439

High

505704

KR109
Keratin-associated protein 10-9

1

20

High-throughput

0.439

High

505705

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

2

High-throughput

0.439

High

505709

GOGA2
Golgin subfamily A member 2

1

20

High-throughput

0.439

High

505717

K1H1
Keratin, type I cuticular Ha1

1

20

High-throughput

0.439

High

505719

CCD57
Coiled-coil domain-containing protein 57

1

3

High-throughput

0.439

High

505724

K1C40
Keratin, type I cytoskeletal 40

1

20

High-throughput

0.439

High

505727

RINT1
RAD50-interacting protein 1

1

2

High-throughput

0.439

High

505730

NT2NA
Notch homolog 2 N-terminal-like protein A

1

20

High-throughput

0.439

High

505737

IHO1
Interactor of HORMAD1 protein 1

1

2

High-throughput

0.439

High

505740

USBP1
Harmonin-binding protein USHBP1

1

6

High-throughput

0.439

High

505742

CBY2
Protein chibby homolog 2

1

4

High-throughput

0.439

High

505743

PNMA1
Paraneoplastic antigen Ma1

1

10

High-throughput

0.439

High

505745

CEP70
Centrosomal protein of 70 kDa

1

11

High-throughput

0.439

High

505751

OSTF1
Osteoclast-stimulating factor 1

1

16

High-throughput

0.439

High

505754

GMPPA
Mannose-1-phosphate guanylyltransferase regulatory subunit alpha

1

1

High-throughput

0.439

High

505755

CC136
Coiled-coil domain-containing protein 136

1

9

High-throughput

0.439

High

505756

RPGR1
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1

1

5

High-throughput

0.439

High

505759

SPAG5
Sperm-associated antigen 5

1

4

High-throughput

0.439

High

505763

KIFC3
Kinesin-like protein KIFC3

1

10

High-throughput

0.439

High

505765

KRA42
Keratin-associated protein 4-2

1

20

High-throughput

0.439

High

505766

CEP44
Centrosomal protein of 44 kDa

1

2

High-throughput

0.439

High

505775

CEP72
Centrosomal protein of 72 kDa

1

6

High-throughput

0.439

High

505779

PNMA2
Paraneoplastic antigen Ma2

1

10

High-throughput

0.439

High

505780

CAPS1
Calcium-dependent secretion activator 1

1

2

High-throughput

0.439

High

505689

F261
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1

2

0

High-throughput

0.316

High

505733

F90A1
Protein FAM90A1

2

0

High-throughput

0.316

High

505749

PIHD2
PIH1 domain-containing protein 2

2

0

High-throughput

0.316

High

505739

CCD33
Coiled-coil domain-containing protein 33

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025