Protein: MAOX
NADP-dependent malic enzyme (NADP-ME) (EC 1.1.1.40) (Malic enzyme 1)

Gene: MAOX, ME1
Organism: Homo sapiens
Interactions: 55
UniProt ID: P48163

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004470 - malic enzyme activity
GO:0004473 - malate dehydrogenase (decarboxylating) (NADP+) activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

870636

MAOX
NADP-dependent malic enzyme

3

5

Small-scale

0.849

High

870637

EFNB2
Ephrin-B2

3

1

High-throughput

0.593

High

547108

PYC
Pyruvate carboxylase, mitochondrial

1

2

Small-scale

0.565

High

703492

MK01
Mitogen-activated protein kinase 1

1

0

Small-scale

0.537

High

870643

VAC14
Protein VAC14 homolog

1

4

High-throughput

0.536

High

370034

CYTC
Cystatin-C

1

0

High-throughput

0.513

High

376980

ANF
Natriuretic peptides A

1

0

High-throughput

0.513

High

391585

FRIH
Ferritin heavy chain

1

0

High-throughput

0.513

High

767039

PTN7
Tyrosine-protein phosphatase non-receptor type 7

1

0

High-throughput

0.513

High

870639

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

870653

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

0

High-throughput

0.513

High

870656

CDK15
Cyclin-dependent kinase 15

1

0

High-throughput

0.513

High

870660

OAZ3
Ornithine decarboxylase antizyme 3

1

0

High-throughput

0.513

High

828627

MDHC
Malate dehydrogenase, cytoplasmic

1

2

Small-scale

0.505

High

185507

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

High-throughput

0.501

High

179164

ARC1B
Actin-related protein 2/3 complex subunit 1B

1

0

High-throughput

0.493

High

241039

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

322915

UBP19
Ubiquitin carboxyl-terminal hydrolase 19

1

3

Small-scale

0.479

High

541393

FGFR1
Fibroblast growth factor receptor 1

1

2

High-throughput

0.479

High

870638

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.479

High

870645

DX39B
Spliceosome RNA helicase DDX39B

1

1

Small-scale

0.479

High

870650

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

870652

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

1

High-throughput

0.479

High

870655

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

1

Small-scale

0.479

High

870659

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

3

Small-scale

0.479

High

519835

ANDR
Androgen receptor

1

0

High-throughput

0.458

High

764534

CTNB1
Catenin beta-1

1

0

High-throughput

0.458

High

830319

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

870642

RING1
E3 ubiquitin-protein ligase RING1

1

0

Small-scale

0.458

High

870644

TRAF3
TNF receptor-associated factor 3

1

0

Small-scale

0.458

High

870648

OTU7B
OTU domain-containing protein 7B

1

0

Small-scale

0.458

High

870651

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

529318

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.445

High

870641

EFNB1
Ephrin-B1

1

1

High-throughput

0.445

High

105545

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

588159

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

694881

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

767655

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

295470

PSD10
26S proteasome non-ATPase regulatory subunit 10

1

0

High-throughput

0.426

High

848005

AL3B1
Aldehyde dehydrogenase family 3 member B1

1

0

High-throughput

0.426

High

870647

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.426

High

870654

ASB9
Ankyrin repeat and SOCS box protein 9

1

0

High-throughput

0.426

High

870658

MYCBP
c-Myc-binding protein

1

0

High-throughput

0.426

High

870661

FCF1
rRNA-processing protein FCF1 homolog

2

0

High-throughput

0.328

High

659662

NFYA
Nuclear transcription factor Y subunit alpha

2

0

High-throughput

0.318

High

325303

OR2A4
Olfactory receptor 2A4

1

0

High-throughput

0.279

Low

870640

DSCR6
Protein ripply3

1

0

High-throughput

0.279

Low

870649

LYPD4
Ly6/PLAUR domain-containing protein 4

1

0

High-throughput

0.279

Low

870657

FCRL5
Fc receptor-like protein 5

1

0

High-throughput

0.279

Low

353092

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

870646

EPHA7
Ephrin type-A receptor 7

1

0

High-throughput

0.249

Low

870662

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.249

Low

213399

ZSC12
Zinc finger and SCAN domain-containing protein 12

1

0

High-throughput

0.232

Low

261123

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025