Protein: NALP2
NACHT, LRR and PYD domains-containing protein 2 (Nucleotide-binding site protein 1) (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2)

Gene: NALP2, NLRP2
Organism: Homo sapiens
Interactions: 50
UniProt ID: Q9NX02

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0006915 - apoptotic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1347596

ASC
Apoptosis-associated speck-like protein containing a CARD

2

18

Small-scale

0.776

High

886448

NALP5
NACHT, LRR and PYD domains-containing protein 5

1

18

High-throughput

0.691

High

1122746

PYDC2
Pyrin domain-containing protein 2

1

15

Small-scale

0.683

High

158551

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

13

Small-scale

0.665

High

167623

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

13

Small-scale

0.665

High

183339

MEFV
Pyrin

1

13

Small-scale

0.618

High

836030

GSK3B
Glycogen synthase kinase-3 beta

1

2

High-throughput

0.618

High

1263222

NALP7
NACHT, LRR and PYD domains-containing protein 7

1

20

Small-scale

0.618

High

1347600

SGT1
Protein SGT1 homolog

2

13

Small-scale

0.612

High

837099

MRE11
Double-strand break repair protein MRE11

2

0

Small-scale

0.559

High

149929

RFXK
DNA-binding protein RFXANK

1

4

High-throughput

0.536

High

154642

TPP1
Tripeptidyl-peptidase 1

1

1

High-throughput

0.536

High

276280

CIB2
Calcium and integrin-binding family member 2

1

1

High-throughput

0.536

High

597549

GSTM3
Glutathione S-transferase Mu 3

1

2

High-throughput

0.536

High

1236533

SIR6
NAD-dependent protein deacylase sirtuin-6

1

3

High-throughput

0.536

High

1284827

EFMT3
EEF1A lysine methyltransferase 3

1

1

High-throughput

0.536

High

1344298

MBNL1
Muscleblind-like protein 1

1

1

High-throughput

0.536

High

1347601

NEMO
NF-kappa-B essential modulator

1

3

Small-scale

0.515

High

158984

NCTR3
Natural cytotoxicity triggering receptor 3

1

0

High-throughput

0.513

High

246051

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.513

High

311771

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

0

High-throughput

0.513

High

335322

DYR
Dihydrofolate reductase

1

0

High-throughput

0.513

High

341470

FA12
Coagulation factor XII

1

0

High-throughput

0.513

High

1309598

BCL7B
B-cell CLL/lymphoma 7 protein family member B

1

0

High-throughput

0.513

High

1318403

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

1332122

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

0

High-throughput

0.513

High

1336353

E41L5
Band 4.1-like protein 5

1

0

High-throughput

0.513

High

1347595

CRIPT
Cysteine-rich PDZ-binding protein

1

0

High-throughput

0.513

High

1347599

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.513

High

1347597

FAF1
FAS-associated factor 1

1

6

Small-scale

0.508

High

1326395

DNAI2
Dynein axonemal intermediate chain 2

1

2

High-throughput

0.489

High

1347598

PSG11
Pregnancy-specific beta-1-glycoprotein 11

1

1

High-throughput

0.489

High

395910

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

432305

HS90A
Heat shock protein HSP 90-alpha

1

7

Small-scale

0.479

High

455934

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.479

High

667493

CASP1
Caspase-1

1

20

Small-scale

0.479

High

1050628

WRN
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN

1

4

Small-scale

0.479

High

1054214

BECN1
Beclin-1

1

6

High-throughput

0.479

High

1191732

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

1

High-throughput

0.479

High

1272043

RAD50
DNA repair protein RAD50

1

2

Small-scale

0.479

High

1035606

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.458

High

522225

CADH1
Cadherin-1

1

2

High-throughput

0.437

High

555666

H2AX
Histone H2AX

1

3

Small-scale

0.437

High

110685

H3BSK8
RB binding protein 6, ubiquitin ligase

1

1

High-throughput

0.407

High

111633

K7ER46
Beclin 1

1

6

High-throughput

0.407

High

1169911

PKHG7
Pleckstrin homology domain-containing family G member 7

1

1

High-throughput

0.407

High

646002

CRBB3
Beta-crystallin B3

1

0

High-throughput

0.279

Low

1071753

TTF1
Transcription termination factor 1

1

0

High-throughput

0.279

Low

1074831

TAF13
Transcription initiation factor TFIID subunit 13

1

0

High-throughput

0.279

Low

1306164

NPAS1
Neuronal PAS domain-containing protein 1

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024