Protein: PIM3
Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)

Gene: PIM3
Organism: Homo sapiens
Interactions: 61
UniProt ID: Q86V86

Gene Ontology (top 5):
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006468 - protein phosphorylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

440615

FYN
Tyrosine-protein kinase Fyn

1

19

High-throughput

0.691

High

463145

YES
Tyrosine-protein kinase Yes

1

19

High-throughput

0.691

High

463621

LYN
Tyrosine-protein kinase Lyn

1

20

High-throughput

0.691

High

557365

SRC
Proto-oncogene tyrosine-protein kinase Src

1

19

High-throughput

0.691

High

692737

CALL3
Calmodulin-like protein 3

1

11

High-throughput

0.691

High

701860

ABCD3
ATP-binding cassette sub-family D member 3

1

2

High-throughput

0.691

High

841020

FRK
Tyrosine-protein kinase FRK

1

20

High-throughput

0.691

High

854140

KI67
Proliferation marker protein Ki-67

1

7

High-throughput

0.691

High

1110487

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

10

High-throughput

0.691

High

1117403

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

6

High-throughput

0.691

High

1290226

LRC59
Leucine-rich repeat-containing protein 59

1

3

High-throughput

0.691

High

1290227

RBM14
RNA-binding protein 14

1

3

High-throughput

0.691

High

1290233

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

1

5

High-throughput

0.691

High

256641

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

5

High-throughput

0.618

High

461662

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.618

High

468559

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.618

High

541037

PIM1
Serine/threonine-protein kinase pim-1

1

18

High-throughput

0.575

High

567442

TCTP
Translationally-controlled tumor protein

1

1

Small-scale

0.552

High

123756

MYO1C
Unconventional myosin-Ic

1

15

High-throughput

0.536

High

179225

ARC1B
Actin-related protein 2/3 complex subunit 1B

1

6

High-throughput

0.536

High

179531

ARPC3
Actin-related protein 2/3 complex subunit 3

1

1

High-throughput

0.536

High

217470

E41L2
Band 4.1-like protein 2

1

10

High-throughput

0.536

High

224739

ACTN4
Alpha-actinin-4

1

3

High-throughput

0.536

High

227916

MYO1B
Unconventional myosin-Ib

1

14

High-throughput

0.536

High

257899

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

1

1

High-throughput

0.536

High

270376

WDR1
WD repeat-containing protein 1

1

7

High-throughput

0.536

High

318354

MYO1D
Unconventional myosin-Id

1

16

High-throughput

0.536

High

385916

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

14

High-throughput

0.536

High

414130

P53
Cellular tumor antigen p53

1

6

High-throughput

0.536

High

415687

HSPB1
Heat shock protein beta-1

1

6

High-throughput

0.536

High

418698

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

7

High-throughput

0.536

High

447799

TPM3
Tropomyosin alpha-3 chain

1

11

High-throughput

0.536

High

464179

TPM2
Tropomyosin beta chain

1

11

High-throughput

0.536

High

475988

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

7

High-throughput

0.536

High

482923

TPM1
Tropomyosin alpha-1 chain

1

11

High-throughput

0.536

High

730731

1433S
14-3-3 protein sigma

1

20

High-throughput

0.536

High

774086

ADDA
Alpha-adducin

1

1

High-throughput

0.536

High

867256

CAPZB
F-actin-capping protein subunit beta

1

6

High-throughput

0.536

High

915128

CAZA1
F-actin-capping protein subunit alpha-1

1

4

High-throughput

0.536

High

920841

ACLY
ATP-citrate synthase

1

2

High-throughput

0.536

High

983523

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

7

High-throughput

0.536

High

984183

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

7

High-throughput

0.536

High

995438

TPM4
Tropomyosin alpha-4 chain

1

11

High-throughput

0.536

High

1010320

BASP1
Brain acid soluble protein 1

1

5

High-throughput

0.536

High

1028810

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

9

High-throughput

0.536

High

1120755

DSG2
Desmoglein-2

1

9

High-throughput

0.536

High

1160678

DREB
Drebrin

1

1

High-throughput

0.536

High

1290231

LIMA1
LIM domain and actin-binding protein 1

1

5

High-throughput

0.536

High

299264

FLOT1
Flotillin-1

1

4

High-throughput

0.489

High

502039

H2AZ
Histone H2A.Z

1

8

High-throughput

0.489

High

569200

CD59
CD59 glycoprotein

1

1

High-throughput

0.489

High

799962

COIL
Coilin

1

2

High-throughput

0.489

High

1162820

H2A2C
Histone H2A type 2-C

1

5

High-throughput

0.489

High

1290229

TMOD3
Tropomodulin-3

1

1

High-throughput

0.489

High

1290232

COR1C
Coronin-1C

1

4

High-throughput

0.489

High

989754

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

6

High-throughput

0.479

High

1028267

MDM2
E3 ubiquitin-protein ligase Mdm2

1

4

Small-scale

0.445

High

1207499

GNAS1
Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas

1

6

High-throughput

0.445

High

868726

LEG7
Galectin-7

1

0

High-throughput

0.426

High

1290228

RPF2
Ribosome production factor 2 homolog

1

0

High-throughput

0.279

Low

1290230

GBG12

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025