Protein: ORML3
ORM1-like protein 3

Gene: ORML3, ORMDL3
Organism: Homo sapiens
Interactions: 62
UniProt ID: Q8N138

Gene Ontology (top 5):
GO:0002903 - negative regulation of B cell apoptotic process
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0006672 - ceramide metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

184872

SPTC1
Serine palmitoyltransferase 1

2

8

Small-scale

0.776

High

332794

KCNK5
Potassium channel subfamily K member 5

2

1

High-throughput

0.606

High

722526

CTR1
High affinity cationic amino acid transporter 1

2

2

High-throughput

0.606

High

1134126

NTCP
Hepatic sodium/bile acid cotransporter

2

3

High-throughput

0.606

High

1142875

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

2

High-throughput

0.606

High

1279327

DHB13
17-beta-hydroxysteroid dehydrogenase 13

2

1

High-throughput

0.606

High

1291419

RETR3
Reticulophagy regulator 3

2

1

High-throughput

0.606

High

1306976

CERS3
Ceramide synthase 3

2

2

High-throughput

0.606

High

1322825

GP152
Probable G-protein coupled receptor 152

2

4

High-throughput

0.606

High

1322832

RNF5
E3 ubiquitin-protein ligase RNF5

2

1

High-throughput

0.606

High

1322833

REEP2
Receptor expression-enhancing protein 2

2

1

High-throughput

0.606

High

1322835

ELOV4
Very long chain fatty acid elongase 4

2

1

High-throughput

0.606

High

1322843

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

3

High-throughput

0.606

High

845076

EAA3
Excitatory amino acid transporter 3

2

0

High-throughput

0.602

High

129879

GET1
Guided entry of tail-anchored proteins factor 1

2

0

High-throughput

0.580

High

1042604

ROM1
Rod outer segment membrane protein 1

2

0

High-throughput

0.580

High

1322821

SYT2
Synaptotagmin-2

2

0

High-throughput

0.580

High

1322830

GP101
Probable G-protein coupled receptor 101

2

0

High-throughput

0.580

High

1322831

TM237
Transmembrane protein 237

2

0

High-throughput

0.580

High

329641

LERL1
Leptin receptor overlapping transcript-like 1

2

1

High-throughput

0.553

High

1108958

AQP6
Aquaporin-6

2

5

High-throughput

0.553

High

1187492

AR13B
ADP-ribosylation factor-like protein 13B

2

1

High-throughput

0.553

High

1207547

F209A
Protein FAM209A

2

1

High-throughput

0.553

High

1322837

IF3M
Translation initiation factor IF-3, mitochondrial

2

2

High-throughput

0.553

High

1322839

S35C2
Solute carrier family 35 member C2

2

2

High-throughput

0.553

High

996240

EF1A1
Elongation factor 1-alpha 1

1

1

High-throughput

0.541

High

1053029

VMAT2
Synaptic vesicular amine transporter

1

2

High-throughput

0.536

High

1270838

SV2A
Synaptic vesicle glycoprotein 2A

1

6

High-throughput

0.536

High

1322824

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

1

1

High-throughput

0.536

High

1322826

AQP3
Aquaporin-3

1

4

High-throughput

0.536

High

1322827

BSCL2
Seipin

1

1

High-throughput

0.536

High

1322836

S22A4
Solute carrier family 22 member 4

1

6

High-throughput

0.536

High

1322840

GABR1
Gamma-aminobutyric acid type B receptor subunit 1

1

1

High-throughput

0.536

High

1322844

SC5A6
Sodium-dependent multivitamin transporter

1

3

High-throughput

0.536

High

877169

KC1D
Casein kinase I isoform delta

1

0

High-throughput

0.513

High

422559

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

848522

MAGA8
Melanoma-associated antigen 8

1

1

High-throughput

0.489

High

1308894

S22A9
Organic anion transporter 7

1

6

High-throughput

0.489

High

1322828

CREL1
Protein disulfide isomerase CRELD1

1

2

High-throughput

0.489

High

1287375

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

2

Small-scale

0.479

High

133769

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

High-throughput

0.458

High

947223

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.458

High

182652

GP182
G-protein coupled receptor 182

1

3

High-throughput

0.445

High

1242857

S39A4
Zinc transporter ZIP4

1

1

High-throughput

0.445

High

385955

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

High-throughput

0.439

High

1322823

LNX1
E3 ubiquitin-protein ligase LNX

1

1

Small-scale

0.439

High

1238733

TECT3
Tectonic-3

1

1

High-throughput

0.437

High

1322841

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

256081

S19A2
Thiamine transporter 1

1

0

High-throughput

0.426

High

561376

TDGF1
Protein Cripto

1

0

High-throughput

0.426

High

1322834

SPY4
Protein sprouty homolog 4

2

0

High-throughput

0.319

High

1315183

CJ067
Uncharacterized protein C10orf67, mitochondrial

2

0

High-throughput

0.316

High

1322822

COQ8A
Atypical kinase COQ8A, mitochondrial

2

0

High-throughput

0.316

High

1053698

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

0

High-throughput

0.282

High

326735

DUS14
Dual specificity protein phosphatase 14

1

0

High-throughput

0.279

Low

1062262

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

0

High-throughput

0.279

Low

1098638

SBP1
Methanethiol oxidase

1

0

High-throughput

0.279

Low

1322838

AT133
Polyamine-transporting ATPase 13A3

1

0

High-throughput

0.279

Low

965084

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.249

Low

479067

CEL3A
Chymotrypsin-like elastase family member 3A

1

0

High-throughput

0.232

Low

1322829

TM169
Transmembrane protein 169

1

0

High-throughput

0.232

Low

1322842

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025