Protein: FIRRM
FIGNL1-interacting regulator of recombination and mitosis (FIDGETIN-like-1 interacting protein) (FLIP) (POLO1-associating protein)

Gene: FIRRM
Organism: Homo sapiens
Interactions: 76
UniProt ID: Q9NSG2

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0000775 - chromosome, centromeric region
GO:0000776 - kinetochore
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1244970

FIGL1
Fidgetin-like protein 1

3

1

Small-scale

0.658

High

1042787

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

2

2

High-throughput

0.611

High

212493

SPIT2
Kunitz-type protease inhibitor 2

3

1

High-throughput

0.609

High

845486

PE2R3
Prostaglandin E2 receptor EP3 subtype

3

2

High-throughput

0.609

High

835402

VIPR2
Vasoactive intestinal polypeptide receptor 2

3

2

High-throughput

0.604

High

1291905

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

3

7

High-throughput

0.593

High

622687

TNR1A
Tumor necrosis factor receptor superfamily member 1A

2

1

High-throughput

0.574

High

630193

ACM3
Muscarinic acetylcholine receptor M3

2

4

High-throughput

0.574

High

665326

EDNRB
Endothelin receptor type B

2

3

High-throughput

0.574

High

770923

OPRM
Mu-type opioid receptor

2

3

High-throughput

0.574

High

939539

FCGRN
IgG receptor FcRn large subunit p51

2

1

High-throughput

0.574

High

1449390

C5AR2
C5a anaphylatoxin chemotactic receptor 2

2

6

High-throughput

0.574

High

351974

S1PR4
Sphingosine 1-phosphate receptor 4

2

4

High-throughput

0.549

High

683346

TNR5
Tumor necrosis factor receptor superfamily member 5

2

1

High-throughput

0.549

High

1101675

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

2

8

High-throughput

0.549

High

638252

S1PR1
Sphingosine 1-phosphate receptor 1

1

3

High-throughput

0.536

High

348759

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

High-throughput

0.513

High

486627

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

640302

EPHA1
Ephrin type-A receptor 1

1

0

High-throughput

0.513

High

906192

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

0

High-throughput

0.513

High

1022973

EFNB1
Ephrin-B1

1

0

High-throughput

0.513

High

1219626

DEN4C
DENN domain-containing protein 4C

1

0

High-throughput

0.513

High

1324870

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.513

High

1415601

AFG2B
ATPase family gene 2 protein homolog B

1

0

High-throughput

0.513

High

1449395

HIG1A
HIG1 domain family member 1A, mitochondrial

1

0

High-throughput

0.513

High

1449396

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

1

0

High-throughput

0.513

High

423282

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

133315

P2Y10
Putative P2Y purinoceptor 10

1

8

High-throughput

0.489

High

182792

GP182
G-protein coupled receptor 182

1

5

High-throughput

0.489

High

466978

ACM4
Muscarinic acetylcholine receptor M4

1

2

High-throughput

0.489

High

640475

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

4

High-throughput

0.489

High

733086

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

2

High-throughput

0.489

High

833876

P2RY2
P2Y purinoceptor 2

1

7

High-throughput

0.489

High

907064

CCR6
C-C chemokine receptor type 6

1

4

High-throughput

0.489

High

936130

PAR2
Proteinase-activated receptor 2

1

8

High-throughput

0.489

High

1449103

GP173
Probable G-protein coupled receptor 173

1

1

High-throughput

0.489

High

1055979

RAD51
DNA repair protein RAD51 homolog 1

1

1

Small-scale

0.481

High

1128191

DMC1
Meiotic recombination protein DMC1/LIM15 homolog

1

1

Small-scale

0.481

High

720701

AGTR1
Type-1 angiotensin II receptor

1

4

High-throughput

0.437

High

171588

S27A2
Long-chain fatty acid transport protein 2

1

0

High-throughput

0.426

High

1244117

TMM88
Transmembrane protein 88

1

0

High-throughput

0.426

High

1449392

FZD10
Frizzled-10

1

0

High-throughput

0.426

High

669368

ACKR3
Atypical chemokine receptor 3

1

5

High-throughput

0.407

High

704084

5HT1E
5-hydroxytryptamine receptor 1E

1

1

High-throughput

0.407

High

1404961

S1PR3
Sphingosine 1-phosphate receptor 3

1

3

High-throughput

0.407

High

1029634

CD83
CD83 antigen

2

0

High-throughput

0.328

High

1278577

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

2

0

High-throughput

0.316

High

1330749

SIGL1
SIGLEC family-like protein 1

2

0

High-throughput

0.313

High

1350897

HUMMR
Protein MGARP

2

0

High-throughput

0.313

High

1399625

OPALI
Opalin

2

0

High-throughput

0.313

High

380163

HLAB
HLA class I histocompatibility antigen, B alpha chain

2

0

High-throughput

0.288

High

854588

S15A1
Solute carrier family 15 member 1

1

0

High-throughput

0.279

Low

1142531

PDCD1
Programmed cell death protein 1

1

0

High-throughput

0.279

Low

1238257

CK087
Uncharacterized protein C11orf87

1

0

High-throughput

0.279

Low

1291692

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.279

Low

1356735

TM263
Transmembrane protein 263

1

0

High-throughput

0.279

Low

1392395

MACIR
Macrophage immunometabolism regulator

1

0

High-throughput

0.279

Low

1406550

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

0

High-throughput

0.279

Low

1430974

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

1449389

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.279

Low

1449391

P2RX2
P2X purinoceptor 2

1

0

High-throughput

0.279

Low

1449393

CLC4A
C-type lectin domain family 4 member A

1

0

High-throughput

0.279

Low

1449397

GPR45
Probable G-protein coupled receptor 45

1

0

High-throughput

0.279

Low

339234

SFT2B
Vesicle transport protein SFT2B

1

0

High-throughput

0.249

Low

50706

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.232

Low

139333

UPK2
Uroplakin-2

1

0

High-throughput

0.232

Low

166424

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

0

High-throughput

0.232

Low

1214134

DIK1A
Divergent protein kinase domain 1A

1

0

High-throughput

0.232

Low

1232137

VASN
Vasorin

1

0

High-throughput

0.232

Low

1335742

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low

1391465

S35A4
Probable UDP-sugar transporter protein SLC35A4

1

0

High-throughput

0.232

Low

1395671

S35E1
Solute carrier family 35 member E1

1

0

High-throughput

0.232

Low

1435998

PACC1
Proton-activated chloride channel

1

0

High-throughput

0.232

Low

1446708

TMM9B
Transmembrane protein 9B

1

0

High-throughput

0.232

Low

1448668

GTR9
Solute carrier family 2, facilitated glucose transporter member 9

1

0

High-throughput

0.232

Low

1449394

XCT
Cystine/glutamate transporter

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025