Protein: AMPD2
AMP deaminase 2 (EC 3.5.4.6) (AMP deaminase isoform L)

Gene: AMPD2
Organism: Homo sapiens
Interactions: 84
UniProt ID: Q01433

Gene Ontology (top 5):
GO:0003876 - AMP deaminase activity
GO:0005829 - cytosol
GO:0006188 - IMP biosynthetic process
GO:0032264 - IMP salvage
GO:0042632 - cholesterol homeostasis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1030305

AMPD2
AMP deaminase 2

3

11

High-throughput

0.861

High

654159

AMPD1
AMP deaminase 1

2

11

High-throughput

0.783

High

1030299

AMPD3
AMP deaminase 3

1

11

High-throughput

0.665

High

966202

1433G
14-3-3 protein gamma

3

7

High-throughput

0.662

High

1030306

1433F
14-3-3 protein eta

3

7

High-throughput

0.662

High

1030316

DCAF8
DDB1- and CUL4-associated factor 8

3

1

High-throughput

0.662

High

1030337

FAME
Factor associated with metabolism and energy

3

0

High-throughput

0.638

High

591278

CD44
CD44 antigen

3

0

High-throughput

0.634

High

729754

1433B
14-3-3 protein beta/alpha

2

7

High-throughput

0.628

High

1030329

LZTS2
Leucine zipper putative tumor suppressor 2

2

1

High-throughput

0.628

High

760427

SDC2
Syndecan-2

4

2

High-throughput

0.627

High

1030311

RNPS1
RNA-binding protein with serine-rich domain 1

3

0

High-throughput

0.616

High

616741

SDC1
Syndecan-1

3

2

High-throughput

0.604

High

1030341

MLX
Max-like protein X

2

0

High-throughput

0.602

High

1030327

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.580

High

1030321

EIF1A
Probable RNA-binding protein EIF1AD

2

0

High-throughput

0.576

High

1030324

DDX17
Probable ATP-dependent RNA helicase DDX17

2

0

High-throughput

0.576

High

575135

IDE
Insulin-degrading enzyme

1

1

High-throughput

0.536

High

690914

1433T
14-3-3 protein theta

1

7

High-throughput

0.536

High

730519

1433S
14-3-3 protein sigma

1

7

High-throughput

0.536

High

971416

1433E
14-3-3 protein epsilon

1

1

High-throughput

0.536

High

990107

1433Z
14-3-3 protein zeta/delta

1

7

High-throughput

0.536

High

1022695

XIAP
E3 ubiquitin-protein ligase XIAP

1

1

High-throughput

0.536

High

295814

FACE1
CAAX prenyl protease 1 homolog

1

0

High-throughput

0.513

High

384657

CRYAB
Alpha-crystallin B chain

1

0

High-throughput

0.513

High

549566

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.513

High

599194

IL7RA
Interleukin-7 receptor subunit alpha

1

0

High-throughput

0.513

High

760825

GLYC
Serine hydroxymethyltransferase, cytosolic

1

0

High-throughput

0.513

High

1030312

KRA61
Keratin-associated protein 6-1

1

0

High-throughput

0.513

High

1030313

KR196
Keratin-associated protein 19-6

1

0

High-throughput

0.513

High

1030314

KR197
Keratin-associated protein 19-7

1

0

High-throughput

0.513

High

1030323

R3GEF
Guanine nucleotide exchange factor for Rab-3A

1

0

High-throughput

0.513

High

1030325

PSMG2
Proteasome assembly chaperone 2

1

0

High-throughput

0.513

High

1030332

ARL6
ADP-ribosylation factor-like protein 6

1

0

High-throughput

0.513

High

1030343

NDK7
Nucleoside diphosphate kinase homolog 7

1

0

High-throughput

0.513

High

861575

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

1

High-throughput

0.501

High

474620

VIME
Vimentin

1

0

High-throughput

0.493

High

726650

SDC4
Syndecan-4

1

2

High-throughput

0.489

High

1030315

PREP
Presequence protease, mitochondrial

1

1

High-throughput

0.489

High

536990

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.479

High

970352

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

1030310

EEA1
Early endosome antigen 1

1

2

High-throughput

0.479

High

222952

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

241425

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

655794

TBG1
Tubulin gamma-1 chain

1

0

High-throughput

0.458

High

700612

PSA5
Proteasome subunit alpha type-5

1

0

Small-scale

0.458

High

942561

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.458

High

1027386

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

0

High-throughput

0.458

High

1030309

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1030330

TCHP
Trichoplein keratin filament-binding protein

1

0

High-throughput

0.458

High

1030333

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

1030339

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1030340

GCP4
Gamma-tubulin complex component 4

1

0

High-throughput

0.458

High

934477

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.445

High

1030335

DDX28
Probable ATP-dependent RNA helicase DDX28

1

1

High-throughput

0.445

High

674138

BRD2
Bromodomain-containing protein 2

1

1

High-throughput

0.437

High

695236

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

413643

P53
Cellular tumor antigen p53

1

0

High-throughput

0.426

High

529648

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

829355

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

1

High-throughput

0.407

High

1030308

CTBP1
C-terminal-binding protein 1

3

0

High-throughput

0.342

High

1030331

HIRP3
HIRA-interacting protein 3

3

0

High-throughput

0.342

High

1030307

EPS8
Epidermal growth factor receptor kinase substrate 8

2

0

High-throughput

0.328

High

1030322

GP156
Probable G-protein coupled receptor 156

2

0

High-throughput

0.328

High

1030334

GPBL1
Vasculin-like protein 1

2

0

High-throughput

0.328

High

332501

CCDB1
Cyclin-D1-binding protein 1

2

0

High-throughput

0.327

High

282519

PAGE1
P antigen family member 1

2

0

High-throughput

0.313

High

1030320

HDGR2
Hepatoma-derived growth factor-related protein 2

2

0

High-throughput

0.313

High

1030342

PHF8
Histone lysine demethylase PHF8

2

0

High-throughput

0.313

High

928419

TERF1
Telomeric repeat-binding factor 1

1

0

High-throughput

0.299

High

1030336

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.288

High

718387

CD6
T-cell differentiation antigen CD6

1

0

High-throughput

0.279

Low

1030317

ANGE2
Protein angel homolog 2

1

0

High-throughput

0.279

Low

1030326

F136A
Protein FAM136A

1

0

High-throughput

0.279

Low

105770

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

279344

TULP3
Tubby-related protein 3

1

0

High-throughput

0.249

Low

411755

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

588487

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

1030318

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1030319

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1030338

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.249

Low

330121

VENTX
Homeobox protein VENTX

1

0

High-throughput

0.232

Low

1030328

EAF1
ELL-associated factor 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025