Protein: TAF1C
TATA box-binding protein-associated factor RNA polymerase I subunit C (RNA polymerase I-specific TBP-associated factor 110 kDa) (TAFI110) (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (Transcription initiation factor SL1/TIF-IB subunit C)

Gene: TAF1C
Organism: Homo sapiens
Interactions: 114
UniProt ID: Q15572

Gene Ontology (top 5):
GO:0001164 - RNA polymerase I core promoter sequence-specific DNA binding
GO:0001181 - RNA polymerase I general transcription initiation factor activity
GO:0001650 - fibrillar center
GO:0005654 - nucleoplasm
GO:0005668 - RNA polymerase transcription factor SL1 complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1150292

TAF1B
TATA box-binding protein-associated factor RNA polymerase I subunit B

6

1

Small-scale

0.730

High

628787

TBP
TATA-box-binding protein

5

1

Small-scale

0.718

High

1150318

TAF1D
TATA box-binding protein-associated factor RNA polymerase I subunit D

5

0

Small-scale

0.696

High

1150288

TAF1A
TATA box-binding protein-associated factor RNA polymerase I subunit A

3

1

Small-scale

0.656

High

1150309

EAF1
ELL-associated factor 1

3

0

High-throughput

0.638

High

208265

RRP8
Ribosomal RNA-processing protein 8

3

0

High-throughput

0.634

High

1150314

TCPH
T-complex protein 1 subunit eta

3

3

High-throughput

0.604

High

841369

RBM34
RNA-binding protein 34

2

0

High-throughput

0.602

High

904760

MECP2
Methyl-CpG-binding protein 2

2

0

High-throughput

0.602

High

972420

RS14
Small ribosomal subunit protein uS11

2

0

High-throughput

0.602

High

288655

NPM3
Nucleoplasmin-3

2

1

High-throughput

0.601

High

447056

NPM
Nucleophosmin

2

1

High-throughput

0.601

High

604671

UBF1
Nucleolar transcription factor 1

2

0

Small-scale

0.577

High

290572

SURF6
Surfeit locus protein 6

2

0

High-throughput

0.576

High

786101

LONM
Lon protease homolog, mitochondrial

2

0

High-throughput

0.576

High

396178

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

1150289

TAF12
Transcription initiation factor TFIID subunit 12

1

0

Small-scale

0.554

High

875975

TCPE
T-complex protein 1 subunit epsilon

2

3

High-throughput

0.549

High

881939

TCPG
T-complex protein 1 subunit gamma

2

3

High-throughput

0.549

High

1007029

TCPB
T-complex protein 1 subunit beta

2

4

High-throughput

0.549

High

1097670

STK3
Serine/threonine-protein kinase 3

2

1

High-throughput

0.549

High

286995

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

2

High-throughput

0.536

High

625405

CSK22
Casein kinase II subunit alpha'

1

1

High-throughput

0.536

High

997735

CSK21
Casein kinase II subunit alpha

1

1

High-throughput

0.536

High

1008741

RED1
Double-stranded RNA-specific editase 1

1

1

High-throughput

0.536

High

1029299

SET
Protein SET

1

0

Small-scale

0.523

High

191332

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

0

High-throughput

0.513

High

339982

RPA1
DNA-directed RNA polymerase I subunit RPA1

1

0

High-throughput

0.513

High

537210

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.513

High

686179

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.513

High

785189

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.513

High

824164

RL13A
Large ribosomal subunit protein uL13

1

0

High-throughput

0.513

High

855091

NOP2
28S rRNA

1

0

High-throughput

0.513

High

975709

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.513

High

978959

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.513

High

985679

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.513

High

986055

RL8
Large ribosomal subunit protein uL2

1

0

High-throughput

0.513

High

1006423

SRPK2
SRSF protein kinase 2

1

0

High-throughput

0.513

High

1099364

SRSF6
Serine/arginine-rich splicing factor 6

1

0

High-throughput

0.513

High

1145217

RNPS1
RNA-binding protein with serine-rich domain 1

1

0

High-throughput

0.513

High

1150295

CC137
Coiled-coil domain-containing protein 137

1

0

High-throughput

0.513

High

1150298

PIAS4
E3 SUMO-protein ligase PIAS4

1

0

High-throughput

0.513

High

1150308

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.513

High

1150316

PDCL3
Phosducin-like protein 3

1

0

High-throughput

0.513

High

1150326

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.513

High

532606

CH60
60 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.489

High

610676

TCPA
T-complex protein 1 subunit alpha

1

3

High-throughput

0.489

High

821365

TCPZ
T-complex protein 1 subunit zeta

1

4

High-throughput

0.489

High

961180

FGF12
Fibroblast growth factor 12

1

1

High-throughput

0.489

High

1150302

TCPW
T-complex protein 1 subunit zeta-2

1

5

High-throughput

0.489

High

1150306

FGF13
Fibroblast growth factor 13

1

1

High-throughput

0.489

High

591662

H2AX
Histone H2AX

1

0

High-throughput

0.486

High

1150290

SMN
Survival motor neuron protein

1

0

High-throughput

0.486

High

1150305

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

1

0

High-throughput

0.486

High

413896

P53
Cellular tumor antigen p53

1

0

Small-scale

0.480

High

1150320

RRN3
RNA polymerase I-specific transcription initiation factor RRN3

1

0

Small-scale

0.480

High

674174

BRD2
Bromodomain-containing protein 2

1

1

High-throughput

0.479

High

1150303

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

129112

MEN1
Menin

1

0

High-throughput

0.458

High

190921

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

Small-scale

0.458

High

372113

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

650776

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

0

High-throughput

0.458

High

810120

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

979711

H4
Histone H4

1

0

High-throughput

0.458

High

1087754

NFIA
Nuclear factor 1 A-type

1

0

High-throughput

0.458

High

1150301

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1150315

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1093110

STK4
Serine/threonine-protein kinase 4

1

1

High-throughput

0.445

High

1150304

SC65
Endoplasmic reticulum protein SC65

1

1

High-throughput

0.445

High

345870

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.437

High

1141137

BRD3
Bromodomain-containing protein 3

1

1

High-throughput

0.437

High

1136772

MO4L2
Mortality factor 4-like protein 2

1

0

High-throughput

0.426

High

1150294

CAVN1
Caveolae-associated protein 1

1

0

High-throughput

0.426

High

1150312

DNJC7
DnaJ homolog subfamily C member 7

1

0

High-throughput

0.426

High

1150297

P3H3
Prolyl 3-hydroxylase 3

1

1

High-throughput

0.407

High

898669

RL14
Large ribosomal subunit protein eL14

3

0

High-throughput

0.347

High

1037508

RL18A
Large ribosomal subunit protein eL20

3

0

High-throughput

0.345

High

961738

RL37A
Large ribosomal subunit protein eL43

2

0

High-throughput

0.328

High

1150307

TRI44
Tripartite motif-containing protein 44

2

0

High-throughput

0.328

High

258893

DNJA2
DnaJ homolog subfamily A member 2

2

0

High-throughput

0.313

High

985181

RL10A
Large ribosomal subunit protein uL1

2

0

High-throughput

0.313

High

1150317

SAV1
Protein salvador homolog 1

2

0

High-throughput

0.313

High

171070

VP26C
Vacuolar protein sorting-associated protein 26C

1

0

High-throughput

0.282

High

191653

MAGB2
Melanoma-associated antigen B2

1

0

High-throughput

0.279

Low

376393

PDGFB
Platelet-derived growth factor subunit B

1

0

High-throughput

0.279

Low

428781

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.279

Low

521706

H14
Histone H1.4

1

0

High-throughput

0.279

Low

615805

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.279

Low

657244

KALM
Anosmin-1

1

0

High-throughput

0.279

Low

859842

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.279

Low

960743

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.279

Low

1127389

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

1150291

RN151
RING finger protein 151

1

0

High-throughput

0.279

Low

1150296

ZN467
Zinc finger protein 467

1

0

High-throughput

0.279

Low

1150300

ZCH10
Zinc finger CCHC domain-containing protein 10

1

0

High-throughput

0.279

Low

1150310

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

0

High-throughput

0.279

Low

1150311

ZNF48
Zinc finger protein 48

1

0

High-throughput

0.279

Low

1150313

MIPEP
Mitochondrial intermediate peptidase

1

0

High-throughput

0.279

Low

1150319

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

0

High-throughput

0.279

Low

1150323

PURG
Purine-rich element-binding protein gamma

1

0

High-throughput

0.279

Low

1150324

BAG5
BAG family molecular chaperone regulator 5

1

0

High-throughput

0.279

Low

1150325

E41L3
Band 4.1-like protein 3

1

0

High-throughput

0.279

Low

389829

TTHY
Transthyretin

1

0

High-throughput

0.265

Low

405466

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.265

Low

105986

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

400881

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.249

Low

505477

SLN14
Protein SLFN14 [Cleaved into: C-terminally truncated SLFN14 endoribonuclease

1

0

High-throughput

0.249

Low

1024593

VIGLN
Vigilin

1

0

High-throughput

0.249

Low

1150322

XPO7
Exportin-7

1

0

High-throughput

0.249

Low

239065

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.232

Low

635319

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

1

0

High-throughput

0.232

Low

1150293

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.232

Low

1150299

RNF10
E3 ubiquitin-protein ligase RNF10

1

0

High-throughput

0.232

Low

1150321

NYNRI
Protein NYNRIN

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025