Protein: RM27
Large ribosomal subunit protein bL27m (39S ribosomal protein L27, mitochondrial) (L27mt) (MRP-L27)

Gene: RM27, MRPL27
Organism: Homo sapiens
Interactions: 186
UniProt ID: Q9P0M9

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003735 - structural constituent of ribosome
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005762 - mitochondrial large ribosomal subunit

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1430527

RM18
Large ribosomal subunit protein uL18m

3

0

High-throughput

0.796

High

1451679

RM16
Large ribosomal subunit protein uL16m

2

1

High-throughput

0.776

High

1094149

RM28
Large ribosomal subunit protein bL28m

5

1

High-throughput

0.712

High

1328320

RM50
Large ribosomal subunit protein mL50

5

1

High-throughput

0.712

High

1418273

RM04
Large ribosomal subunit protein uL4m

5

2

High-throughput

0.712

High

1439611

RM47
Large ribosomal subunit protein uL29m

4

1

High-throughput

0.691

High

1418214

RM09
Large ribosomal subunit protein bL9m

4

1

High-throughput

0.683

High

969495

RS8
Small ribosomal subunit protein eS8

3

1

High-throughput

0.667

High

1452661

RM39
Large ribosomal subunit protein mL39

4

0

High-throughput

0.664

High

914781

RM12
Large ribosomal subunit protein bL12m

3

1

High-throughput

0.662

High

994847

YBOX1
Y-box-binding protein 1

3

2

Small-scale

0.662

High

1123465

ICT1
Large ribosomal subunit protein mL62

4

0

High-throughput

0.661

High

1419665

RM37
Large ribosomal subunit protein mL37

4

0

High-throughput

0.661

High

1446059

RT30
Large ribosomal subunit protein mL65

4

0

High-throughput

0.661

High

882398

RM19
Large ribosomal subunit protein bL19m

3

1

High-throughput

0.650

High

1275862

RM21
Large ribosomal subunit protein bL21m

3

1

High-throughput

0.650

High

1418160

RM13
Large ribosomal subunit protein uL13m

3

2

High-throughput

0.650

High

1437118

RM44
Large ribosomal subunit protein mL44

3

1

High-throughput

0.650

High

1448965

RM17
Large ribosomal subunit protein bL17m

3

2

High-throughput

0.650

High

686491

RL13
Large ribosomal subunit protein eL13

3

0

High-throughput

0.638

High

1281359

RM10
Large ribosomal subunit protein uL10m

3

0

High-throughput

0.634

High

1312788

RM41
Large ribosomal subunit protein mL41

3

0

High-throughput

0.634

High

1453230

RM35
Large ribosomal subunit protein bL35m

3

0

High-throughput

0.634

High

1453919

RM42
Large ribosomal subunit protein mL42

3

0

High-throughput

0.634

High

1418112

RM20
Large ribosomal subunit protein bL20m

3

0

High-throughput

0.622

High

1450797

RT18A
Large ribosomal subunit protein mL66

3

0

High-throughput

0.622

High

1449898

DDX28
Probable ATP-dependent RNA helicase DDX28

1

1

High-throughput

0.618

High

1027814

HNRPU
Heterogeneous nuclear ribonucleoprotein U

2

1

High-throughput

0.611

High

1331705

RM43
Large ribosomal subunit protein mL43

2

1

High-throughput

0.611

High

1387986

RM38
Large ribosomal subunit protein mL38

2

1

High-throughput

0.611

High

1453669

RM15
Large ribosomal subunit protein uL15m

2

2

High-throughput

0.611

High

1453917

RM11
Large ribosomal subunit protein uL11m

2

1

High-throughput

0.611

High

477881

RM03
Large ribosomal subunit protein uL3m

2

2

High-throughput

0.601

High

1213365

RM02
Large ribosomal subunit protein uL2m

2

2

High-throughput

0.601

High

1418327

RM01
Large ribosomal subunit protein uL1m

2

1

High-throughput

0.601

High

1453916

YBOX2
Y-box-binding protein 2

2

2

High-throughput

0.601

High

694037

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.586

High

1388300

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.586

High

76061

B4DEF8
Large ribosomal subunit protein mL45

2

0

High-throughput

0.585

High

1104149

RM49
Large ribosomal subunit protein mL49

2

0

High-throughput

0.585

High

280067

RM33
Large ribosomal subunit protein bL33m

2

0

High-throughput

0.576

High

1158319

RM23
Large ribosomal subunit protein uL23m

2

0

High-throughput

0.576

High

1196183

RM51
Large ribosomal subunit protein mL51

2

0

High-throughput

0.576

High

1281142

RM55
Large ribosomal subunit protein mL55

2

0

High-throughput

0.576

High

1287568

RM52
Large ribosomal subunit protein mL52

2

0

High-throughput

0.576

High

1347112

G45IP
Large ribosomal subunit protein mL64

2

0

High-throughput

0.576

High

1349574

RM30
Large ribosomal subunit protein uL30m

2

0

High-throughput

0.576

High

1382316

RM24
Large ribosomal subunit protein uL24m

2

0

High-throughput

0.576

High

1391630

RM48
Large ribosomal subunit protein mL48

2

0

High-throughput

0.576

High

1409990

RM34
Large ribosomal subunit protein bL34m

2

0

High-throughput

0.576

High

1418075

RM32
Large ribosomal subunit protein bL32m

2

0

High-throughput

0.576

High

1446751

RM40
Large ribosomal subunit protein mL40

2

0

High-throughput

0.576

High

1451510

RM22
Large ribosomal subunit protein uL22m

2

0

High-throughput

0.576

High

979315

RS6
Small ribosomal subunit protein eS6

2

1

High-throughput

0.571

High

1048742

SSBP
Single-stranded DNA-binding protein, mitochondrial

2

0

High-throughput

0.559

High

214348

MSI1H
RNA-binding protein Musashi homolog 1

1

2

High-throughput

0.536

High

586930

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.536

High

809893

RS19
Small ribosomal subunit protein eS19

1

1

High-throughput

0.536

High

824406

RL13A
Large ribosomal subunit protein uL13

1

2

High-throughput

0.536

High

860390

RS9
Small ribosomal subunit protein uS4

1

1

High-throughput

0.536

High

960004

RS3A
Small ribosomal subunit protein eS1

1

1

High-throughput

0.536

High

1016657

SRSF3
Serine/arginine-rich splicing factor 3

1

2

High-throughput

0.536

High

1148817

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

2

High-throughput

0.536

High

1415563

GNL3
Guanine nucleotide-binding protein-like 3

1

2

High-throughput

0.536

High

1432251

RM46
Large ribosomal subunit protein mL46

1

1

High-throughput

0.536

High

1437382

LN28A
Protein lin-28 homolog A

1

2

High-throughput

0.536

High

316094

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.517

High

425855

PCCA
Propionyl-CoA carboxylase alpha chain, mitochondrial

1

0

High-throughput

0.513

High

425968

PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial

1

0

High-throughput

0.513

High

429032

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.513

High

612804

RL7
Large ribosomal subunit protein uL30

1

0

High-throughput

0.513

High

616027

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.513

High

842581

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.513

High

964172

RL37
Large ribosomal subunit protein eL37

1

0

High-throughput

0.513

High

1009351

PRR3
Proline-rich protein 3

1

0

High-throughput

0.513

High

1016272

RL19
Large ribosomal subunit protein eL19

1

0

High-throughput

0.513

High

1057936

RL18
Large ribosomal subunit protein eL18

1

0

High-throughput

0.513

High

1141562

OXA1L
Mitochondrial inner membrane protein OXA1L

1

0

High-throughput

0.513

High

1240548

RM54
Large ribosomal subunit protein mL54

1

0

High-throughput

0.513

High

1242649

FAHD1
Oxaloacetate tautomerase FAHD1, mitochondrial

1

0

High-throughput

0.513

High

1341337

COQ8A
Atypical kinase COQ8A, mitochondrial

1

0

High-throughput

0.513

High

1389031

MASU1
Mitochondrial assembly of ribosomal large subunit protein 1

1

0

High-throughput

0.513

High

1389304

RM53
Large ribosomal subunit protein mL53

1

0

High-throughput

0.513

High

1410507

RT63
Large ribosomal subunit protein mL63

1

0

High-throughput

0.513

High

419245

H2A1B
Histone H2A type 1-B/E

1

1

High-throughput

0.489

High

502576

H2A1
Histone H2A type 1

1

1

High-throughput

0.489

High

1251057

RBMS3
RNA-binding motif, single-stranded-interacting protein 3

1

2

High-throughput

0.489

High

423355

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

1453918

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

282118

MPPB
Mitochondrial-processing peptidase subunit beta

1

2

High-throughput

0.479

High

284244

SRS10
Serine/arginine-rich splicing factor 10

1

2

High-throughput

0.479

High

287404

RF1M
Peptide chain release factor 1, mitochondrial

1

2

High-throughput

0.479

High

351027

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

1

High-throughput

0.479

High

485479

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

1

High-throughput

0.479

High

508746

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.479

High

725669

CPSM
Carbamoyl-phosphate synthase [ammonia], mitochondrial

1

1

High-throughput

0.479

High

856414

IF2M
Translation initiation factor IF-2, mitochondrial

1

1

High-throughput

0.479

High

988226

TRA2B
Transformer-2 protein homolog beta

1

2

High-throughput

0.479

High

1083787

MPPA
Mitochondrial-processing peptidase subunit alpha

1

2

High-throughput

0.479

High

1111889

TRA2A
Transformer-2 protein homolog alpha

1

4

High-throughput

0.479

High

1215874

RC3H1
Roquin-1

1

1

High-throughput

0.479

High

1412468

TACO1
Translational activator of cytochrome c oxidase 1

1

1

High-throughput

0.479

High

1413034

MTG1
Mitochondrial ribosome-associated GTPase 1

1

2

High-throughput

0.479

High

1428758

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

1

High-throughput

0.479

High

1432643

MTRFR
Mitochondrial translation release factor in rescue

1

2

High-throughput

0.479

High

1438059

RC3H2
Roquin-2

1

1

High-throughput

0.479

High

1451696

NHP2
H/ACA ribonucleoprotein complex subunit 2

1

1

High-throughput

0.479

High

1453911

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

2

High-throughput

0.479

High

61667

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.458

High

66321

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.458

High

183762

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.458

High

279958

CISY
Citrate synthase, mitochondrial

1

0

High-throughput

0.458

High

533024

CH60
60 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.458

High

828995

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

842004

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

852064

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

882932

EFTU
Elongation factor Tu, mitochondrial

1

0

High-throughput

0.458

High

935214

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

1039432

RL6
Large ribosomal subunit protein eL6

1

0

High-throughput

0.458

High

1058336

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1092261

NFX1
Transcriptional repressor NF-X1

1

0

High-throughput

0.458

High

1117872

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.458

High

1142693

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

1234556

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

1270666

COX15
Heme A synthase COX15

1

0

High-throughput

0.458

High

1310484

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.458

High

1381761

FAKD4
FAST kinase domain-containing protein 4

1

0

High-throughput

0.458

High

1383572

MCUR1
Mitochondrial calcium uniporter regulator 1

1

0

High-throughput

0.458

High

1384898

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

1388441

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.458

High

1401647

EFGM
Elongation factor G, mitochondrial

1

0

High-throughput

0.458

High

1412609

CQ080
Mitochondrial nucleoid-associated protein 1

1

0

High-throughput

0.458

High

1414109

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.458

High

1415695

TR61B
tRNA

1

0

High-throughput

0.458

High

1416573

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

0

High-throughput

0.458

High

1418918

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

1431986

IF3M
Translation initiation factor IF-3, mitochondrial

1

0

High-throughput

0.458

High

1433745

MTG2
Mitochondrial ribosome-associated GTPase 2

1

0

High-throughput

0.458

High

1435818

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1436124

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

1446270

NGRN
Neugrin

1

0

High-throughput

0.458

High

1450456

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

1451265

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

0

High-throughput

0.458

High

1451459

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

1453910

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

1209747

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.445

High

1290179

THOC4
THO complex subunit 4

1

2

High-throughput

0.445

High

1450588

ATD3A
ATPase family AAA domain-containing protein 3A

1

1

High-throughput

0.445

High

373359

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.437

High

406749

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.437

High

668053

CDK2
Cyclin-dependent kinase 2

1

1

High-throughput

0.437

High

913604

KIF11
Kinesin-like protein KIF11

1

1

High-throughput

0.437

High

1341039

THOC2
THO complex subunit 2

1

1

High-throughput

0.437

High

1368402

REQU
Zinc finger protein ubi-d4

1

1

High-throughput

0.437

High

1368654

KAT6A
Histone acetyltransferase KAT6A

1

1

High-throughput

0.437

High

653627

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

1116607

FHL3
Four and a half LIM domains protein 3

3

0

High-throughput

0.352

High

1358870

KBTB7
Kelch repeat and BTB domain-containing protein 7

2

0

High-throughput

0.328

High

1391639

ZN274
Neurotrophin receptor-interacting factor homolog

2

0

High-throughput

0.328

High

391507

FRIL
Ferritin light chain

2

0

High-throughput

0.313

High

1260455

H1FNT
Testis-specific H1 histone

2

0

High-throughput

0.313

High

183370

ZN185
Zinc finger protein 185

1

0

High-throughput

0.279

Low

207885

ZZEF1
Zinc finger ZZ-type and EF-hand domain-containing protein 1

1

0

High-throughput

0.279

Low

225710

AAKB2
5'-AMP-activated protein kinase subunit beta-2

1

0

High-throughput

0.279

Low

287737

KS6A5
Ribosomal protein S6 kinase alpha-5

1

0

High-throughput

0.279

Low

317379

ACL6B
Actin-like protein 6B

1

0

High-throughput

0.279

Low

338996

CBX6
Chromobox protein homolog 6

1

0

High-throughput

0.279

Low

376434

PDGFB
Platelet-derived growth factor subunit B

1

0

High-throughput

0.279

Low

649449

H1T
Histone H1t

1

0

High-throughput

0.279

Low

1356141

THAP3
THAP domain-containing protein 3

1

0

High-throughput

0.279

Low

1390649

NEIL1
Endonuclease 8-like 1

1

0

High-throughput

0.279

Low

1391817

AURKB
Aurora kinase B

1

0

High-throughput

0.279

Low

1407766

FOXB1
Forkhead box protein B1

1

0

High-throughput

0.279

Low

1453915

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

0

High-throughput

0.279

Low

559013

LYL1
Protein lyl-1

1

0

High-throughput

0.249

Low

593233

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.249

Low

600211

ZNF22
Zinc finger protein 22

1

0

High-throughput

0.249

Low

971213

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

1005191

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1015867

RHOG
Rho-related GTP-binding protein RhoG

1

0

High-throughput

0.249

Low

1332786

TDRD5
Tudor domain-containing protein 5

1

0

High-throughput

0.249

Low

1453912

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

1453914

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.249

Low

58957

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

0

High-throughput

0.232

Low

1196356

ZNG1F
Zinc-regulated GTPase metalloprotein activator 1F

1

0

High-throughput

0.232

Low

1453913

FBW1B
F-box/WD repeat-containing protein 11

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025