Protein: TMCO3
Transmembrane and coiled-coil domain-containing protein 3 (Putative LAG1-interacting protein)

Gene: TMCO3
Organism: Homo sapiens
Interactions: 73
UniProt ID: Q6UWJ1

Gene Ontology (top 5):
GO:0015386 - potassium:proton antiporter activity
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

228091

PM34
Peroxisomal membrane protein PMP34

2

2

High-throughput

0.628

High

1043217

TAP2
Antigen peptide transporter 2

2

2

High-throughput

0.628

High

1248494

AT133
Polyamine-transporting ATPase 13A3

2

2

High-throughput

0.628

High

1248496

AT132
Polyamine-transporting ATPase 13A2

2

3

High-throughput

0.628

High

62967

POTEF
POTE ankyrin domain family member F

2

0

High-throughput

0.602

High

248594

FADS1
Acyl-CoA

2

0

High-throughput

0.602

High

800216

VKGC
Vitamin K-dependent gamma-carboxylase

2

0

High-throughput

0.602

High

1127840

ERG1
Squalene monooxygenase

2

0

High-throughput

0.602

High

1248477

ATG9A
Autophagy-related protein 9A

2

0

High-throughput

0.602

High

1248478

ADCK2
Uncharacterized aarF domain-containing protein kinase 2

2

0

High-throughput

0.602

High

1248497

PXMP2
Peroxisomal membrane protein 2

2

0

High-throughput

0.602

High

1248502

PSME2
Proteasome activator complex subunit 2

2

0

High-throughput

0.602

High

363445

EGFR
Epidermal growth factor receptor

2

0

Small-scale

0.582

High

1238988

NIPA3
Magnesium transporter NIPA3

2

0

High-throughput

0.576

High

1085441

SRBP2
Sterol regulatory element-binding protein 2

2

1

High-throughput

0.574

High

1114901

CUL4A
Cullin-4A

2

3

High-throughput

0.574

High

1115260

CUL4B
Cullin-4B

2

3

High-throughput

0.574

High

1191846

TBB8
Tubulin beta-8 chain

2

1

High-throughput

0.574

High

669013

FPR2
N-formyl peptide receptor 2

1

4

High-throughput

0.536

High

552281

ADT3
ADP/ATP translocase 3

1

0

High-throughput

0.513

High

934221

BI1
Bax inhibitor 1

1

0

High-throughput

0.513

High

1248493

S26A6
Solute carrier family 26 member 6

1

0

High-throughput

0.513

High

596998

TSHR
Thyrotropin receptor

1

1

High-throughput

0.494

High

165968

FFAR1
Free fatty acid receptor 1

1

3

High-throughput

0.489

High

1108571

TBB3
Tubulin beta-3 chain

1

1

High-throughput

0.489

High

1248484

EFNMT
eEF1A lysine and N-terminal methyltransferase

1

1

High-throughput

0.489

High

1113460

CUL3
Cullin-3

1

3

High-throughput

0.479

High

846074

GLP1R
Glucagon-like peptide 1 receptor

1

0

Small-scale

0.460

High

722495

CTR1
High affinity cationic amino acid transporter 1

1

1

High-throughput

0.445

High

1248500

SCN3B
Sodium channel regulatory subunit beta-3

1

1

High-throughput

0.445

High

351227

MOT3
Monocarboxylate transporter 3

1

0

High-throughput

0.426

High

1139462

S39AE
Metal cation symporter ZIP14

1

0

High-throughput

0.426

High

1248481

S35F2
Solute carrier family 35 member F2

1

0

High-throughput

0.426

High

1248487

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

1

0

High-throughput

0.426

High

1248491

CLCC1
Chloride channel CLIC-like protein 1

1

0

High-throughput

0.426

High

886080

CXCR3
C-X-C chemokine receptor type 3

1

4

High-throughput

0.407

High

956913

CXCR4
C-X-C chemokine receptor type 4

1

4

High-throughput

0.407

High

1101540

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

2

High-throughput

0.407

High

1199529

KLH22
Kelch-like protein 22

1

1

High-throughput

0.407

High

1248482

S15A3
Solute carrier family 15 member 3

1

1

High-throughput

0.407

High

714627

TYK2
Non-receptor tyrosine-protein kinase TYK2

2

0

High-throughput

0.328

High

943073

STX17
Syntaxin-17

2

0

High-throughput

0.328

High

1215310

DCAF8
DDB1- and CUL4-associated factor 8

2

0

High-throughput

0.328

High

1248479

DAAF5
Dynein axonemal assembly factor 5

2

0

High-throughput

0.328

High

1248483

GUF1
Translation factor GUF1, mitochondrial

2

0

High-throughput

0.328

High

1248485

FNDC5
Fibronectin type III domain-containing protein 5

2

0

High-throughput

0.328

High

1248492

PIGQ
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q

2

0

High-throughput

0.328

High

1248495

COG4
Conserved oligomeric Golgi complex subunit 4

2

0

High-throughput

0.328

High

1248498

PLCE
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon

2

0

High-throughput

0.328

High

1248499

IFT57
Intraflagellar transport protein 57 homolog

2

0

High-throughput

0.328

High

1248504

HEMK1
MTRF1L release factor glutamine methyltransferase

2

0

High-throughput

0.328

High

415655

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.282

High

253851

TPST2
Protein-tyrosine sulfotransferase 2

1

0

High-throughput

0.279

Low

261630

CATL2
Cathepsin L2

1

0

High-throughput

0.279

Low

618392

TSN8
Tetraspanin-8

1

0

High-throughput

0.279

Low

996992

TBA4A
Tubulin alpha-4A chain

1

0

High-throughput

0.279

Low

1116996

LAMB3
Laminin subunit beta-3

1

0

High-throughput

0.279

Low

1197241

MBRL
Membralin

1

0

High-throughput

0.279

Low

1213751

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.279

Low

1248476

DPH6
Diphthine--ammonia ligase

1

0

High-throughput

0.279

Low

1248480

SPA12
Serpin A12

1

0

High-throughput

0.279

Low

1248486

DR9C7
Short-chain dehydrogenase/reductase family 9C member 7

1

0

High-throughput

0.279

Low

1248488

BRI3B
BRI3-binding protein

1

0

High-throughput

0.279

Low

1248490

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

0

High-throughput

0.279

Low

218345

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

1220993

FBW10
F-box/WD repeat-containing protein 10

1

0

High-throughput

0.249

Low

1248503

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.249

Low

170820

CLGN
Calmegin

1

0

High-throughput

0.232

Low

596494

CTLA4
Cytotoxic T-lymphocyte protein 4

1

0

High-throughput

0.232

Low

704026

5HT1E
5-hydroxytryptamine receptor 1E

1

0

High-throughput

0.232

Low

1246077

GTR7
Solute carrier family 2, facilitated glucose transporter member 7

1

0

High-throughput

0.232

Low

1248489

SAAL1
Protein SAAL1

1

0

High-throughput

0.232

Low

1248501

MS18A
Protein Mis18-alpha

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025