Protein: RCL1
RNA 3'-terminal phosphate cyclase-like protein

Gene: RCL1
Organism: Homo sapiens
Interactions: 104
UniProt ID: Q9Y2P8

Gene Ontology (top 5):
GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000479 - endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 - endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0004521 - RNA endonuclease activity
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1058181

BMS1
Ribosome biogenesis protein BMS1 homolog

3

2

Small-scale

0.662

High

348289

MYC
Myc proto-oncogene protein

2

3

High-throughput

0.584

High

935395

H31
Histone H3.1

2

1

High-throughput

0.584

High

370757

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

841939

CDK9
Cyclin-dependent kinase 9

2

0

High-throughput

0.559

High

1086047

IF16
Gamma-interferon-inducible protein 16

2

0

High-throughput

0.559

High

1251085

SNIP1
Smad nuclear-interacting protein 1

2

0

Small-scale

0.559

High

595477

LMNB1
Lamin-B1

1

1

High-throughput

0.536

High

607850

USF1
Upstream stimulatory factor 1

1

4

High-throughput

0.536

High

839546

SPB9
Serpin B9

1

2

High-throughput

0.536

High

1307465

SH3G3
Endophilin-A3

2

1

High-throughput

0.521

High

121045

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

High-throughput

0.513

High

236851

CCNT1
Cyclin-T1

1

0

High-throughput

0.513

High

418809

NPM
Nucleophosmin

1

0

High-throughput

0.513

High

996970

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.513

High

1333351

GEMI7
Gem-associated protein 7

1

0

High-throughput

0.513

High

1376999

PIN4
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4

1

0

High-throughput

0.513

High

1078070

HERC1
Probable E3 ubiquitin-protein ligase HERC1

1

2

High-throughput

0.489

High

163498

XPO1
Exportin-1

1

2

High-throughput

0.479

High

268341

EED
Polycomb protein EED

1

1

High-throughput

0.479

High

278892

DNJC8
DnaJ homolog subfamily C member 8

1

1

High-throughput

0.479

High

295426

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

554098

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

603796

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

2

High-throughput

0.479

High

632960

TYY1
Transcriptional repressor protein YY1

1

1

High-throughput

0.479

High

652654

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

721826

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

759900

RS19
Small ribosomal subunit protein eS19

1

1

High-throughput

0.479

High

916974

RS6
Small ribosomal subunit protein eS6

1

1

High-throughput

0.479

High

940765

NOP14
Nucleolar protein 14

1

1

High-throughput

0.479

High

1030044

TIF1B
Transcription intermediary factor 1-beta

1

1

Small-scale

0.479

High

1035063

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

1

High-throughput

0.479

High

1242476

PAPD5
Terminal nucleotidyltransferase 4B

1

1

High-throughput

0.479

High

1259885

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

1

1

High-throughput

0.479

High

1264215

DNJC9
DnaJ homolog subfamily C member 9

1

1

High-throughput

0.479

High

1269976

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

1294148

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.479

High

1301834

RANB9
Ran-binding protein 9

1

1

High-throughput

0.479

High

1304192

RING2
E3 ubiquitin-protein ligase RING2

1

1

High-throughput

0.479

High

1348187

AATF
Protein AATF

1

1

High-throughput

0.479

High

1348283

DDX56
Probable ATP-dependent RNA helicase DDX56

1

1

High-throughput

0.479

High

1354920

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

123108

MEN1
Menin

1

0

High-throughput

0.458

High

199847

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

0

High-throughput

0.458

High

258255

DNJB6
DnaJ homolog subfamily B member 6

1

0

High-throughput

0.458

High

445591

RSSA
Small ribosomal subunit protein uS2

1

0

High-throughput

0.458

High

508782

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.458

High

570614

PTN2
Tyrosine-protein phosphatase non-receptor type 2

1

0

High-throughput

0.458

High

582572

NUCL
Nucleolin

1

0

High-throughput

0.458

High

749980

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

824554

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

851004

HDGF
Hepatoma-derived growth factor

1

0

High-throughput

0.458

High

1036224

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1063696

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

1158816

TAF2
Transcription initiation factor TFIID subunit 2

1

0

High-throughput

0.458

High

1189977

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.458

High

1204712

DDX42
ATP-dependent RNA helicase DDX42

1

0

High-throughput

0.458

High

1221854

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1235835

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

0

High-throughput

0.458

High

1256492

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1263589

PSPC1
Paraspeckle component 1

1

0

High-throughput

0.458

High

1285793

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

1286497

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

1300294

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

1

0

High-throughput

0.458

High

1304670

POP1
Ribonucleases P/MRP protein subunit POP1

1

0

High-throughput

0.458

High

1309084

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

0

High-throughput

0.458

High

1315746

NUSAP
Nucleolar and spindle-associated protein 1

1

0

High-throughput

0.458

High

1327752

NSRP1
Nuclear speckle splicing regulatory protein 1

1

0

High-throughput

0.458

High

1343820

ANLN
Anillin

1

0

High-throughput

0.458

High

1344545

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.458

High

1350129

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

1377338

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.458

High

103508

G4U4J3
PAP associated domain containing 5

1

1

High-throughput

0.445

High

402648

JUN
Transcription factor Jun

1

1

High-throughput

0.445

High

909356

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.437

High

1052357

SRC8
Src substrate cortactin

1

1

High-throughput

0.437

High

1136366

RC3H1
Roquin-1

1

1

High-throughput

0.437

High

1172346

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1331672

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

1335245

RC3H2
Roquin-2

1

1

High-throughput

0.437

High

1350509

HECW2
E3 ubiquitin-protein ligase HECW2

1

1

High-throughput

0.437

High

1357013

HECD1
E3 ubiquitin-protein ligase HECTD1

1

1

High-throughput

0.437

High

414402

RB
Retinoblastoma-associated protein

1

0

High-throughput

0.426

High

1057733

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.426

High

995321

GOGA2
Golgin subfamily A member 2

2

0

High-throughput

0.316

High

1031727

GRB10
Growth factor receptor-bound protein 10

2

0

High-throughput

0.298

High

1159755

RHGBA
Rho GTPase-activating protein 11A

2

0

High-throughput

0.298

High

307478

LETM1
Mitochondrial proton/calcium exchanger protein

1

0

High-throughput

0.279

Low

1160828

EMB
Embigin

1

0

High-throughput

0.279

Low

1161524

ULK3
Serine/threonine-protein kinase ULK3

1

0

High-throughput

0.279

Low

1245374

TTL
Tubulin--tyrosine ligase

1

0

High-throughput

0.279

Low

1270166

TFG
Protein TFG

1

0

High-throughput

0.279

Low

1349336

ARHGC
Rho guanine nucleotide exchange factor 12

1

0

High-throughput

0.279

Low

1356008

KLH21
Kelch-like protein 21

1

0

High-throughput

0.279

Low

149445

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

298903

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.249

Low

323335

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.249

Low

375117

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.249

Low

959780

VIGLN
Vigilin

1

0

High-throughput

0.249

Low

1053696

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.249

Low

1201779

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.249

Low

1312649

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.249

Low

1134797

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.232

Low

1169477

TIFAB
TRAF-interacting protein with FHA domain-containing protein B

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024