Protein: LCE1B
Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A)

Gene: LCE1B
Organism: Homo sapiens
Interactions: 89
UniProt ID: Q5T7P3

Gene Ontology (top 5):
GO:0031424 - keratinization
GO:0042802 - identical protein binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

303145

RGS20
Regulator of G-protein signaling 20

5

1

High-throughput

0.659

High

885280

HXA1
Homeobox protein Hox-A1

5

2

High-throughput

0.659

High

1214330

KRA32
Keratin-associated protein 3-2

5

1

High-throughput

0.659

High

685870

KRA59
Keratin-associated protein 5-9

5

20

High-throughput

0.654

High

1214329

KRA42
Keratin-associated protein 4-2

4

20

High-throughput

0.644

High

1214324

KRA92
Keratin-associated protein 9-2

4

20

High-throughput

0.639

High

1214311

NT2NA
Notch homolog 2 N-terminal-like protein A

4

1

High-throughput

0.639

High

950278

KR107
Keratin-associated protein 10-7

4

20

High-throughput

0.637

High

950516

KR108
Keratin-associated protein 10-8

4

20

High-throughput

0.637

High

950785

KR109
Keratin-associated protein 10-9

4

20

High-throughput

0.637

High

1214318

KR412
Keratin-associated protein 4-12

4

20

High-throughput

0.637

High

949711

KR101
Keratin-associated protein 10-1

4

20

High-throughput

0.624

High

221141

SPY2
Protein sprouty homolog 2

3

6

High-throughput

0.617

High

733158

OTX1
Homeobox protein OTX1

3

1

High-throughput

0.617

High

1214308

ATL4
ADAMTS-like protein 4

3

1

High-throughput

0.616

High

159059

LCE2B
Late cornified envelope protein 2B

2

1

High-throughput

0.606

High

1213892

LCE1C
Late cornified envelope protein 1C

2

3

High-throughput

0.606

High

1213935

LCE1D
Late cornified envelope protein 1D

2

1

High-throughput

0.606

High

1213978

LCE1E
Late cornified envelope protein 1E

2

2

High-throughput

0.606

High

1214015

LCE1F
Late cornified envelope protein 1F

2

1

High-throughput

0.606

High

1214252

LCE1A
Late cornified envelope protein 1A

2

1

High-throughput

0.606

High

1214295

LCE1B
Late cornified envelope protein 1B

2

1

High-throughput

0.606

High

1214296

LCE3B
Late cornified envelope protein 3B

2

2

High-throughput

0.606

High

1214297

LCE4A
Late cornified envelope protein 4A

2

1

High-throughput

0.606

High

1214298

LCE2A
Late cornified envelope protein 2A

2

3

High-throughput

0.606

High

1214299

LCE2C
Late cornified envelope protein 2C

2

5

High-throughput

0.606

High

1214300

LCE2D
Late cornified envelope protein 2D

2

5

High-throughput

0.606

High

1214301

LCE5A
Late cornified envelope protein 5A

2

1

High-throughput

0.606

High

950070

KR105
Keratin-associated protein 10-5

3

20

High-throughput

0.597

High

652327

TGM1
Protein-glutamine gamma-glutamyltransferase K

2

0

High-throughput

0.580

High

1212894

LCE3C
Late cornified envelope protein 3C

2

0

High-throughput

0.580

High

221362

SPY1
Protein sprouty homolog 1

2

6

High-throughput

0.578

High

1214322

KRA94
Keratin-associated protein 9-4

2

20

High-throughput

0.573

High

949559

KR123
Keratin-associated protein 12-3

2

5

High-throughput

0.561

High

1214333

KRA15
Keratin-associated protein 1-5

2

20

High-throughput

0.561

High

70264

CRTP1
Cysteine-rich tail protein 1

2

1

High-throughput

0.553

High

221421

SPY3
Protein sprouty homolog 3

2

6

High-throughput

0.553

High

654511

FBLN1
Fibulin-1

2

3

High-throughput

0.553

High

948280

KR121
Keratin-associated protein 12-1

2

5

High-throughput

0.553

High

1214303

KR511
Keratin-associated protein 5-11

2

20

High-throughput

0.553

High

1214304

KRA57
Keratin-associated protein 5-7

2

20

High-throughput

0.553

High

1214305

KRA56
Keratin-associated protein 5-6

2

1

High-throughput

0.553

High

1214306

KRA54
Keratin-associated protein 5-4

2

20

High-throughput

0.553

High

1214307

KRA53
Keratin-associated protein 5-3

2

20

High-throughput

0.553

High

1214309

KRA52
Keratin-associated protein 5-2

2

1

High-throughput

0.553

High

1214314

KRA13
Keratin-associated protein 1-3

2

20

High-throughput

0.553

High

1214315

TRI42
Tripartite motif-containing protein 42

2

1

High-throughput

0.553

High

1214321

KRA98
Keratin-associated protein 9-8

2

20

High-throughput

0.553

High

1214323

KRA93
Keratin-associated protein 9-3

2

20

High-throughput

0.553

High

1214325

KR411
Keratin-associated protein 4-11

2

20

High-throughput

0.553

High

1214326

KRA41
Keratin-associated protein 4-1

2

20

High-throughput

0.553

High

1214327

KRA45
Keratin-associated protein 4-5

2

20

High-throughput

0.553

High

1214328

KRA44
Keratin-associated protein 4-4

2

20

High-throughput

0.553

High

1214331

KRA31
Keratin-associated protein 3-1

2

1

High-throughput

0.553

High

1214334

RGS17
Regulator of G-protein signaling 17

2

1

High-throughput

0.553

High

949897

KR103
Keratin-associated protein 10-3

2

20

High-throughput

0.526

High

1186741

KRA63
Keratin-associated protein 6-3

1

1

High-throughput

0.515

High

517026

NT2NC
Notch homolog 2 N-terminal-like protein C

1

1

High-throughput

0.470

High

950936

KR10B
Keratin-associated protein 10-11

1

20

High-throughput

0.470

High

1214332

KRA24
Keratin-associated protein 2-4

1

20

High-throughput

0.470

High

426095

PPB1
Alkaline phosphatase, placental type

1

1

High-throughput

0.439

High

505334

KRA23
Keratin-associated protein 2-3

1

20

High-throughput

0.439

High

948337

KR122
Keratin-associated protein 12-2

1

20

High-throughput

0.439

High

948715

KR10A
Keratin-associated protein 10-10

1

20

High-throughput

0.439

High

949656

KR124
Keratin-associated protein 12-4

1

1

High-throughput

0.439

High

950164

KR106
Keratin-associated protein 10-6

1

20

High-throughput

0.439

High

1059654

KRA11
Keratin-associated protein 1-1

1

20

High-throughput

0.439

High

1214302

VASN
Vasorin

1

1

High-throughput

0.439

High

1214335

CHIC2
Cysteine-rich hydrophobic domain-containing protein 2

1

1

High-throughput

0.439

High

1214317

MDFI
MyoD family inhibitor

2

0

High-throughput

0.327

High

354440

NAPSA
Napsin-A

2

0

High-throughput

0.316

High

452285

PDIA1
Protein disulfide-isomerase

2

0

High-throughput

0.316

High

705390

GRN
Progranulin

2

0

High-throughput

0.316

High

892207

MCSP
Sperm mitochondrial-associated cysteine-rich protein

2

0

High-throughput

0.316

High

1004680

RNF4
E3 ubiquitin-protein ligase RNF4

2

0

High-throughput

0.316

High

1145975

K1H1
Keratin, type I cuticular Ha1

2

0

High-throughput

0.316

High

1214312

NUFP2
FMR1-interacting protein NUFIP2

2

0

High-throughput

0.316

High

1214313

KR111
Keratin-associated protein 11-1

2

0

High-throughput

0.316

High

1214319

FUCO2
Plasma alpha-L-fucosidase

2

0

High-throughput

0.316

High

1214320

KR171
Keratin-associated protein 17-1

2

0

High-throughput

0.316

High

893915

MEOX2
Homeobox protein MOX-2

1

0

High-throughput

0.299

High

1214310

BEND5
BEN domain-containing protein 5

1

0

High-throughput

0.299

High

245969

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.268

Low

301467

WFS1
Wolframin

1

0

High-throughput

0.268

Low

843643

HD
Huntingtin

1

0

High-throughput

0.268

Low

1214336

RNF11
RING finger protein 11

1

0

High-throughput

0.268

Low

540

NBPFJ
NBPF family member NBPF19

1

0

High-throughput

0.251

Low

1214316

CTSR1
Cation channel sperm-associated protein 1

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025