Protein: CENPU
Inner kinetochore subunit AME1 (Associated with microtubules and essential protein 1) (CENP-U homolog) (Constitutive centromere-associated network protein AME1)

Gene: CENPU, AME1
Organism: Saccharomyces cerevisiae S288C
Interactions: 72
UniProt ID: P38313

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0000817 - COMA complex
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005816 - spindle pole body

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

730786

CENPA
Histone H3-like centromeric protein CSE4

10

1

Small-scale

0.752

High

748305

CENPO
Inner kinetochore subunit MCM21

9

1

Small-scale

0.750

High

748294

CENPQ
Inner kinetochore subunit OKP1

16

0

Small-scale

0.731

High

748281

DSN1
Kinetochore-associated protein DSN1

14

0

Small-scale

0.725

High

748286

NNF1
Kinetochore-associated protein NNF1

10

0

Small-scale

0.722

High

748300

CENPP
Inner kinetochore subunit CTF19

10

0

Small-scale

0.721

High

748273

MTW1
Kinetochore-associated protein MTW1

9

0

Small-scale

0.719

High

748306

NSL1
Kinetochore-associated protein NSL1

8

0

Small-scale

0.714

High

747506

CENPL
Inner kinetochore subunit IML3

8

0

Small-scale

0.711

High

748270

CENPN
Inner kinetochore subunit CHL4

6

0

Small-scale

0.697

High

748308

CENPH
Inner kinetochore subunit MCM16

6

0

Small-scale

0.696

High

748304

NKP2
Inner kinetochore subunit NKP2

5

0

Small-scale

0.677

High

748309

NKP1
Inner kinetochore subunit NKP1

5

0

Small-scale

0.672

High

748310

CENPI
Inner kinetochore subunit CTF3

5

0

Small-scale

0.669

High

356441

H4
Histone H4

4

0

Small-scale

0.648

High

748287

CENPK
Inner kinetochore subunit MCM22

3

0

Small-scale

0.622

High

707991

NUF2
Kinetochore protein NUF2

3

0

Small-scale

0.622

High

748291

SP105
Spindle pole body component SPC105

3

0

Small-scale

0.614

High

355880

H2B2
Histone H2B.2

3

0

Small-scale

0.613

High

392114

H2A1
Histone H2A.1

3

0

Small-scale

0.613

High

716089

CENPC
Inner kinetochore subunit MIF2

3

0

Small-scale

0.613

High

748284

CENPT
Inner kinetochore subunit CNN1

3

0

Small-scale

0.606

High

703786

PRS6B
26S proteasome regulatory subunit 6B homolog

2

0

Small-scale

0.594

High

748297

H3
Histone H3

2

1

Small-scale

0.584

High

748298

HSK3
DASH complex subunit HSK3

2

0

High-throughput

0.576

High

748274

LIS1
Nuclear distribution protein PAC1

2

0

High-throughput

0.570

High

691900

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

2

0

Small-scale

0.559

High

748269

CENPU
Inner kinetochore subunit AME1

2

0

Small-scale

0.559

High

748280

NDC80
Kinetochore protein NDC80

2

0

Small-scale

0.559

High

748302

KRE28
Spindle pole body component KRE28

2

0

Small-scale

0.559

High

748303

SPC24
Kinetochore protein SPC24

2

0

Small-scale

0.559

High

748307

PSH1
RING finger protein PSH1

2

0

Small-scale

0.559

High

748278

SSB2
Ribosome-associated molecular chaperone SSB2

2

1

High-throughput

0.552

High

748296

MPS1
Serine/threonine-protein kinase MPS1

1

1

High-throughput

0.536

High

339601

CDK1
Cyclin-dependent kinase 1

1

1

Small-scale

0.501

High

565567

PHO85
Cyclin-dependent protein kinase PHO85

1

1

Small-scale

0.501

High

624628

PCL1
PHO85 cyclin-1

1

0

Small-scale

0.480

High

747733

SLI15
Inner centromere protein-related protein SLI15

1

0

Small-scale

0.480

High

409987

NOT3
General negative regulator of transcription subunit 3

1

0

High-throughput

0.460

High

587845

AP1
AP-1-like transcription factor YAP1

1

0

High-throughput

0.460

High

605637

KIN3
Serine/threonine-protein kinase KIN3

1

0

High-throughput

0.460

High

748272

END3
Actin cytoskeleton-regulatory complex protein END3

1

0

High-throughput

0.460

High

748275

VAB2
Biogenesis of lysosome-related organelles complex 1 subunit VAB2

1

0

High-throughput

0.460

High

748279

MED3
Mediator of RNA polymerase II transcription subunit 3

1

0

High-throughput

0.460

High

748285

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

0

High-throughput

0.460

High

748290

NBP1
NAP1-binding protein

1

0

High-throughput

0.460

High

748295

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.460

High

748299

PRS8
26S proteasome regulatory subunit 8 homolog

1

0

High-throughput

0.460

High

662072

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

667575

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

716127

CBF3C
Centromere DNA-binding protein complex CBF3 subunit C

1

0

Small-scale

0.458

High

748271

IPL1
Spindle assembly checkpoint kinase

1

0

Small-scale

0.458

High

748276

SPC25
Kinetochore protein SPC25

1

0

Small-scale

0.458

High

748282

CBF3B
Centromere DNA-binding protein complex CBF3 subunit B

1

0

Small-scale

0.458

High

748288

SKP1
Suppressor of kinetochore protein 1

1

0

Small-scale

0.458

High

748292

YBP2
YAP1-binding protein 2

1

0

Small-scale

0.458

High

748293

DAM1
DASH complex subunit DAM1

1

0

High-throughput

0.458

High

748301

SPC19
DASH complex subunit SPC19

1

0

High-throughput

0.458

High

748311

CENPW
Inner kinetochore subunit WIP1

1

0

Small-scale

0.458

High

491052

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

493820

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

511118

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

694595

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

680660

HS104
Heat shock protein 104

1

0

High-throughput

0.426

High

748289

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

516873

SIR4
Regulatory protein SIR4

1

0

High-throughput

0.251

Low

690190

CDC3
Cell division control protein 3

1

0

High-throughput

0.251

Low

748277

TSC11
Target of rapamycin complex 2 subunit TSC11

1

0

High-throughput

0.251

Low

748283

BNI1
Protein BNI1

1

0

High-throughput

0.249

Low

748312

CENPX
Inner kinetochore subunit MHF2

1

0

Small-scale

0.249

Low

748313

CENPS
Inner kinetochore subunit MHF1

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024