Protein: RPA34
DNA-directed RNA polymerase I subunit RPA34 (A34) (DNA-directed DNA-dependent RNA polymerase 34.5 kDa polypeptide) (A34.5)

Gene: RPA34
Organism: Saccharomyces cerevisiae S288C
Interactions: 100
UniProt ID: P47006

Gene Ontology (top 5):
GO:0003899 - DNA-directed RNA polymerase activity
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0005736 - RNA polymerase I complex
GO:0006360 - transcription by RNA polymerase I

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

864034

RPA49
DNA-directed RNA polymerase I subunit RPA49

8

0

Small-scale

0.911

High

644949

RPA2
DNA-directed RNA polymerase I subunit RPA135

6

0

High-throughput

0.884

High

459121

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

4

0

High-throughput

0.831

High

864017

RPA34
DNA-directed RNA polymerase I subunit RPA34

2

0

High-throughput

0.753

High

645071

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

2

0

High-throughput

0.736

High

534277

RPA1
DNA-directed RNA polymerase I subunit RPA190

7

0

Small-scale

0.706

High

858232

RPA43
DNA-directed RNA polymerase I subunit RPA43

4

0

Small-scale

0.653

High

632181

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

3

0

High-throughput

0.622

High

632272

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

3

0

High-throughput

0.622

High

700017

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

3

0

High-throughput

0.622

High

739537

RPA12
DNA-directed RNA polymerase I subunit RPA12

3

0

Small-scale

0.616

High

864025

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

2

0

High-throughput

0.606

High

864040

TMA23
Protein TMA23

2

0

High-throughput

0.587

High

864052

NOP58
Nucleolar protein 58

2

1

Small-scale

0.586

High

579645

HSC82
ATP-dependent molecular chaperone HSC82

3

1

High-throughput

0.578

High

864023

RPA14
DNA-directed RNA polymerase I subunit RPA14

2

0

High-throughput

0.576

High

694580

SPT5
Transcription elongation factor SPT5

2

0

Small-scale

0.569

High

826620

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.559

High

864032

CDC14
Tyrosine-protein phosphatase CDC14

2

0

High-throughput

0.559

High

864035

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.536

High

864038

RNT1
Ribonuclease 3

1

0

Small-scale

0.529

High

738221

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

1

0

High-throughput

0.518

High

817411

HMF1
Protein HMF1

1

0

High-throughput

0.518

High

864053

NOP10
H/ACA ribonucleoprotein complex subunit NOP10

1

0

High-throughput

0.518

High

454456

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.513

High

722050

XPO1
Exportin-1

1

0

High-throughput

0.513

High

864044

NOP12
Nucleolar protein 12

1

0

High-throughput

0.493

High

864050

NSI1
RNA polymerase I termination factor

1

0

High-throughput

0.493

High

864051

NOP56
Nucleolar protein 56

1

1

Small-scale

0.481

High

448755

SNF1
Carbon catabolite-derepressing protein kinase

1

0

High-throughput

0.480

High

656525

KC11
Casein kinase I homolog 1

1

0

High-throughput

0.480

High

864033

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

0

High-throughput

0.480

High

392956

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.479

High

864018

NET1
Nucleolar protein NET1

1

1

High-throughput

0.479

High

864030

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

1

Small-scale

0.479

High

864037

TOF2
Topoisomerase 1-associated factor 2

1

1

High-throughput

0.479

High

415232

TOP1
DNA topoisomerase 1

1

0

Small-scale

0.460

High

864027

PXR1
Protein PXR1

1

0

Small-scale

0.460

High

149839

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

364611

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.458

High

436039

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

436452

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

512519

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

632356

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.458

High

670874

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

677465

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.458

High

679825

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

689537

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

707492

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

795959

RRN10
RNA polymerase I-specific transcription initiation factor RRN10

1

0

High-throughput

0.458

High

823715

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.458

High

826027

ULP2
Ubiquitin-like-specific protease 2

1

0

Small-scale

0.458

High

844514

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

864020

HGH1
Protein HGH1

1

0

Small-scale

0.458

High

864028

RRN9
RNA polymerase I-specific transcription initiation factor RRN9

1

0

High-throughput

0.458

High

864043

RBS1
RNA-binding suppressor of PAS kinase protein 1

1

0

Small-scale

0.458

High

864045

SGO1
Shugoshin

1

0

High-throughput

0.458

High

864047

HFI1
SAGA complex subunit HFI1

1

0

Small-scale

0.458

High

864048

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

864049

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

486233

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.426

High

545376

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

782367

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.426

High

864031

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.426

High

812438

LAA1
AP-1 accessory protein LAA1

2

0

High-throughput

0.313

High

826137

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.282

High

864029

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.279

Low

757711

EDE1
EH domain-containing and endocytosis protein 1

1

0

High-throughput

0.269

Low

692390

KCC1
Calcium/calmodulin-dependent protein kinase I

1

0

High-throughput

0.261

Low

864024

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.261

Low

383776

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

455138

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

514706

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

751427

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.249

Low

753450

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

795072

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

796977

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.249

Low

816822

FMP52
Protein FMP52, mitochondrial

1

0

High-throughput

0.249

Low

864019

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.249

Low

864021

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

864022

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

864026

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

864036

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

864039

RT51
Small ribosomal subunit protein bS1m

1

0

High-throughput

0.249

Low

864041

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.249

Low

864042

POB3
FACT complex subunit POB3

1

0

High-throughput

0.249

Low

864046

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

864054

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.249

Low

358261

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.232

Low

365096

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.232

Low

386766

TBB
Tubulin beta chain

1

0

High-throughput

0.232

Low

394683

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

450609

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.232

Low

453665

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.232

Low

536037

SEC7
ADP-ribosylation factor guanine nucleotide-exchange factor SEC7

1

0

High-throughput

0.232

Low

592339

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

597495

EF3A
Elongation factor 3A

1

0

High-throughput

0.232

Low

618603

FAS2
Fatty acid synthase subunit alpha

1

0

High-throughput

0.232

Low

836766

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025