Protein: MCM10
Minichromosome maintenance protein 10 (Protein DNA43)

Gene: MCM10
Organism: Saccharomyces cerevisiae S288C
Interactions: 79
UniProt ID: P32354

Gene Ontology (top 5):
GO:0000727 - double-strand break repair via break-induced replication
GO:0000781 - chromosome, telomeric region
GO:0003688 - DNA replication origin binding
GO:0003690 - double-stranded DNA binding
GO:0003697 - single-stranded DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

735367

MCM10
Minichromosome maintenance protein 10

4

3

Small-scale

0.891

High

712953

MCM2
DNA replication licensing factor MCM2

11

13

Small-scale

0.761

High

735394

MCM6
DNA replication licensing factor MCM6

9

14

Small-scale

0.758

High

721353

MCM4
DNA replication licensing factor MCM4

10

14

Small-scale

0.757

High

735412

CDC45
Cell division control protein 45

9

2

Small-scale

0.753

High

735376

MCM7
DNA replication licensing factor MCM7

8

12

Small-scale

0.744

High

664421

MCM3
DNA replication licensing factor MCM3

7

12

Small-scale

0.741

High

713246

MCM5
Minichromosome maintenance protein 5

6

13

Small-scale

0.734

High

735384

PSF2
DNA replication complex GINS protein PSF2

3

1

Small-scale

0.660

High

561298

DPOLA
DNA polymerase alpha catalytic subunit A

3

2

Small-scale

0.646

High

444750

SIR2
NAD-dependent histone deacetylase SIR2

3

0

Small-scale

0.636

High

735406

SLD5
DNA replication complex GINS protein SLD5

3

2

Small-scale

0.633

High

586439

PCNA
Proliferating cell nuclear antigen

3

0

Small-scale

0.632

High

735418

PSF1
DNA replication complex GINS protein PSF1

2

2

Small-scale

0.619

High

440916

CDC7
Cell division control protein 7

2

5

Small-scale

0.602

High

734247

DBF4
DDK kinase regulatory subunit DBF4

2

1

Small-scale

0.602

High

444834

SIR3
Regulatory protein SIR3

2

5

Small-scale

0.595

High

735368

ORC2
Origin recognition complex subunit 2

2

3

Small-scale

0.595

High

735397

ORC1
Origin recognition complex subunit 1

2

5

Small-scale

0.595

High

735404

MEC3
DNA damage checkpoint control protein MEC3

2

0

Small-scale

0.588

High

632842

PRI2
DNA primase large subunit

2

0

Small-scale

0.559

High

735393

ORC5
Origin recognition complex subunit 5

1

1

Small-scale

0.501

High

735399

ORC4
Origin recognition complex subunit 4

1

4

Small-scale

0.501

High

735386

ACA2
ATF/CREB activator 2

1

0

High-throughput

0.493

High

735407

HMO1
High mobility group protein 1

1

0

High-throughput

0.493

High

735373

CENPA
Histone H3-like centromeric protein CSE4

1

3

Small-scale

0.481

High

364404

CDK1
Cyclin-dependent kinase 1

1

0

Small-scale

0.480

High

646337

RAD53
Serine/threonine-protein kinase RAD53

1

0

Small-scale

0.480

High

735390

CDT1
Cell division cycle protein CDT1

1

0

Small-scale

0.480

High

735398

ORC3
Origin recognition complex subunit 3

1

0

Small-scale

0.480

High

735375

DPOA2
DNA polymerase alpha subunit B

1

1

Small-scale

0.479

High

735388

MPH1
ATP-dependent DNA helicase MPH1

1

1

High-throughput

0.479

High

735400

H3
Histone H3

1

3

Small-scale

0.479

High

735371

CENPC
Inner kinetochore subunit MIF2

1

0

High-throughput

0.460

High

735382

MTW1
Kinetochore-associated protein MTW1

1

0

High-throughput

0.460

High

735391

NNF1
Kinetochore-associated protein NNF1

1

0

High-throughput

0.460

High

735395

KNL1
Outer kinetochore KNL1 complex subunit SPC105

1

0

High-throughput

0.460

High

735401

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

0

High-throughput

0.460

High

735405

CENPP
Inner kinetochore subunit CTF19

1

0

High-throughput

0.460

High

735370

CNS1
Hsp70/Hsp90 co-chaperone CNS1

1

0

High-throughput

0.458

High

735372

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

735374

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.458

High

735387

FAF1
Protein FAF1

1

0

High-throughput

0.458

High

735402

CTF4
DNA polymerase alpha-binding protein

1

0

Small-scale

0.458

High

735408

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

735411

BRE1
E3 ubiquitin-protein ligase BRE1

1

0

Small-scale

0.458

High

735414

DDC1
DNA damage checkpoint protein 1

1

0

Small-scale

0.458

High

523335

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

526157

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

544138

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

735383

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

735415

PSF3
DNA replication complex GINS protein PSF3

1

1

Small-scale

0.445

High

735380

GDS1
GTPase-GDP dissociation stimulator BEM4

1

0

High-throughput

0.438

High

735381

MET30
F-box protein MET30

1

0

High-throughput

0.438

High

735409

CIAO1
Cytosolic iron-sulfur protein assembly protein 1

1

0

High-throughput

0.438

High

735410

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.438

High

504097

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

735417

6P22
6-phosphofructo-2-kinase 2

1

1

High-throughput

0.437

High

735379

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

735385

6P21
6-phosphofructo-2-kinase 1

1

1

High-throughput

0.407

High

678855

CSM1
Monopolin complex subunit CSM1

1

0

High-throughput

0.251

Low

735389

STU2
Protein STU2

1

0

High-throughput

0.251

Low

735396

CENPQ
Inner kinetochore subunit OKP1

1

0

High-throughput

0.251

Low

149647

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.249

Low

409996

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

433514

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

512318

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

512882

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

514516

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

674480

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.249

Low

689327

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

735369

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

735377

YBU6
Probable thioesterase YBR096W

1

0

High-throughput

0.249

Low

735378

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

735392

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

735403

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

735413

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

735416

HSP42
Heat shock protein 42

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025