Protein: AGK
Acylglycerol kinase, mitochondrial (hAGK) (EC 2.7.1.107) (EC 2.7.1.138) (EC 2.7.1.94) (Multiple substrate lipid kinase) (HsMuLK) (MuLK) (Multi-substrate lipid kinase)

Gene: AGK
Organism: Homo sapiens
Interactions: 131
UniProt ID: Q53H12

Gene Ontology (top 5):
GO:0001729 - ceramide kinase activity
GO:0004143 - ATP-dependent diacylglycerol kinase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1121326

TIM29
Mitochondrial import inner membrane translocase subunit Tim29

4

0

Small-scale

0.849

High

1121351

T10B
Mitochondrial import inner membrane translocase subunit Tim10 B

3

0

Small-scale

0.816

High

905471

TIM10
Mitochondrial import inner membrane translocase subunit Tim10

2

0

High-throughput

0.770

High

1121352

TIM9
Mitochondrial import inner membrane translocase subunit Tim9

1

1

High-throughput

0.691

High

227650

PRKN
E3 ubiquitin-protein ligase parkin

4

0

High-throughput

0.648

High

871913

AT12A
Potassium-transporting ATPase alpha chain 2

2

1

High-throughput

0.628

High

1121293

AGK
Acylglycerol kinase, mitochondrial

1

4

Small-scale

0.618

High

864220

CCHL
Holocytochrome c-type synthase

2

0

High-throughput

0.602

High

1121315

AP3S1
AP-3 complex subunit sigma-1

2

0

High-throughput

0.602

High

1121337

RAB18
Ras-related protein Rab-18

2

0

High-throughput

0.602

High

1121346

ZRAN1
Ubiquitin thioesterase ZRANB1

2

1

High-throughput

0.584

High

779531

CCNF
Cyclin-F

2

0

High-throughput

0.559

High

592292

RAB5A
Ras-related protein Rab-5A

2

0

High-throughput

0.547

High

1121316

BAD
Bcl2-associated agonist of cell death

2

0

High-throughput

0.547

High

1121318

OTUB1
Ubiquitin thioesterase OTUB1

2

0

High-throughput

0.547

High

160928

RAB7L
Ras-related protein Rab-7L1

1

2

High-throughput

0.536

High

162819

XPO1
Exportin-1

1

1

High-throughput

0.536

High

529213

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.536

High

530899

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

2

High-throughput

0.536

High

632294

TNR6
Tumor necrosis factor receptor superfamily member 6

1

2

High-throughput

0.536

High

863775

LIMK1
LIM domain kinase 1

1

2

High-throughput

0.536

High

949801

CBX1
Chromobox protein homolog 1

1

1

High-throughput

0.536

High

958291

AT2C1
Calcium-transporting ATPase type 2C member 1

1

1

High-throughput

0.536

High

1121339

PAK6
Serine/threonine-protein kinase PAK 6

1

1

High-throughput

0.536

High

1064

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.530

High

1041716

CUL3
Cullin-3

1

0

High-throughput

0.513

High

1050968

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.513

High

1121304

TBA1A
Tubulin alpha-1A chain

1

0

High-throughput

0.513

High

1121308

EFNMT
eEF1A lysine and N-terminal methyltransferase

1

0

High-throughput

0.513

High

1121325

NEUR1
Sialidase-1

1

0

High-throughput

0.513

High

1121336

AGO4
Protein argonaute-4

1

0

High-throughput

0.513

High

1121349

C2CD2
C2 domain-containing protein 2

1

0

High-throughput

0.513

High

1121353

COX11
Cytochrome c oxidase assembly protein COX11, mitochondrial

1

0

High-throughput

0.513

High

791625

HD
Huntingtin

1

0

High-throughput

0.493

High

1121296

ECM29
Proteasome adapter and scaffold protein ECM29

1

1

High-throughput

0.489

High

1121317

RSPRY
RING finger and SPRY domain-containing protein 1

1

2

High-throughput

0.489

High

125505

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

3

Small-scale

0.479

High

274551

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

1

High-throughput

0.479

High

299263

FARP2
FERM, ARHGEF and pleckstrin domain-containing protein 2

1

1

High-throughput

0.479

High

374334

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

5

High-throughput

0.479

High

375750

GBA1
Lysosomal acid glucosylceramidase

1

1

Small-scale

0.479

High

377378

GCR
Glucocorticoid receptor

1

4

High-throughput

0.479

High

384953

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.479

High

526403

HEM1
5-aminolevulinate synthase, non-specific, mitochondrial

1

1

Small-scale

0.479

High

568692

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

1

Small-scale

0.479

High

713817

RYK
Tyrosine-protein kinase RYK

1

3

Small-scale

0.479

High

717897

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.479

High

718914

PHB1
Prohibitin 1

1

2

High-throughput

0.479

High

799919

PPIC
Peptidyl-prolyl cis-trans isomerase C

1

1

Small-scale

0.479

High

998799

EP300
Histone acetyltransferase p300

1

2

High-throughput

0.479

High

1035803

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

1051306

DCTN1
Dynactin subunit 1

1

2

High-throughput

0.479

High

1063842

TNIP1
TNFAIP3-interacting protein 1

1

2

High-throughput

0.479

High

1086536

AT2B3
Plasma membrane calcium-transporting ATPase 3

1

1

Small-scale

0.479

High

1121297

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.479

High

1121300

SCMC1
Mitochondrial adenyl nucleotide antiporter SLC25A24

1

1

Small-scale

0.479

High

1121302

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

2

High-throughput

0.479

High

1121306

ZN598
E3 ubiquitin-protein ligase ZNF598

1

2

High-throughput

0.479

High

1121313

FBF1
Fas-binding factor 1

1

4

High-throughput

0.479

High

1121319

AURKB
Aurora kinase B

1

1

High-throughput

0.479

High

1121323

SFXN2
Sideroflexin-2

1

1

Small-scale

0.479

High

1121332

Q9H4D1
Protein kinase

1

2

High-throughput

0.479

High

1121335

SFXN1
Sideroflexin-1

1

1

High-throughput

0.479

High

1121338

BRD7
Bromodomain-containing protein 7

1

2

High-throughput

0.479

High

1121345

WWOX
WW domain-containing oxidoreductase

1

2

High-throughput

0.479

High

122805

MEN1
Menin

1

0

High-throughput

0.458

High

130518

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.458

High

173586

NPHP1
Nephrocystin-1

1

0

High-throughput

0.458

High

258458

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

298563

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

505412

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

0

Small-scale

0.458

High

684785

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.458

High

908652

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1049059

TRI14
Tripartite motif-containing protein 14

1

0

High-throughput

0.458

High

1062231

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

0

Small-scale

0.458

High

1064377

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

Small-scale

0.458

High

1119535

MIDN
Midnolin

1

0

High-throughput

0.458

High

1121298

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1121309

POC5
Centrosomal protein POC5

1

0

High-throughput

0.458

High

1121312

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1121334

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1121340

ANLN
Anillin

1

0

High-throughput

0.458

High

1121341

FBX6
F-box only protein 6

1

0

High-throughput

0.458

High

1121343

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.458

High

1121344

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1121350

TIM22
Mitochondrial import inner membrane translocase subunit Tim22

1

0

Small-scale

0.458

High

271770

PRDM1
PR domain zinc finger protein 1

1

1

High-throughput

0.457

High

1121328

KLF16
Krueppel-like factor 16

1

2

High-throughput

0.457

High

394854

A4
Amyloid-beta precursor protein

1

1

Small-scale

0.445

High

883525

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

2

High-throughput

0.445

High

973935

M2OM
Mitochondrial 2-oxoglutarate/malate carrier protein

1

2

High-throughput

0.445

High

352124

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

1

High-throughput

0.437

High

379472

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.437

High

903277

WDR5
WD repeat-containing protein 5

1

1

High-throughput

0.437

High

1121303

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

1121310

PCSK9
Proprotein convertase subtilisin/kexin type 9

1

1

Small-scale

0.437

High

1121324

RING2
E3 ubiquitin-protein ligase RING2

1

1

High-throughput

0.437

High

1121333

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

1121342

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

2

High-throughput

0.437

High

1121348

HECD1
E3 ubiquitin-protein ligase HECTD1

1

3

High-throughput

0.437

High

497138

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

1121294

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

346961

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.407

High

195912

TTI1
TELO2-interacting protein 1 homolog

1

0

High-throughput

0.279

Low

595252

LMNB1
Lamin-B1

1

0

High-throughput

0.279

Low

975382

TNAP2
Tumor necrosis factor alpha-induced protein 2

1

0

High-throughput

0.279

Low

1085201

PRSS8
Prostasin

1

0

High-throughput

0.279

Low

1121295

GP107
Protein GPR107

1

0

High-throughput

0.279

Low

1121305

DYM
Dymeclin

1

0

High-throughput

0.279

Low

1121307

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.279

Low

1121321

INT4
Integrator complex subunit 4

1

0

High-throughput

0.279

Low

1121347

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.279

Low

182781

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.249

Low

214290

SPOP
Speckle-type POZ protein

1

0

High-throughput

0.249

Low

215746

GTPB6
Putative GTP-binding protein 6

1

0

Small-scale

0.249

Low

262472

TULP3
Tubby-related protein 3

1

0

High-throughput

0.249

Low

307894

SNX4
Sorting nexin-4

1

0

Small-scale

0.249

Low

525953

IFM1
Interferon-induced transmembrane protein 1

1

0

High-throughput

0.249

Low

1065471

S39AE
Metal cation symporter ZIP14

1

0

Small-scale

0.249

Low

1072902

DHC24
Delta(24)-sterol reductase

1

0

Small-scale

0.249

Low

1121299

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.249

Low

1121301

CNNM4
Metal transporter CNNM4

1

0

Small-scale

0.249

Low

1121311

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

1121314

ASM3B
Acid sphingomyelinase-like phosphodiesterase 3b

1

0

Small-scale

0.249

Low

1121320

TECT2
Tectonic-2

1

0

High-throughput

0.249

Low

1121322

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

1121327

DERL1
Derlin-1

1

0

High-throughput

0.249

Low

1121329

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.249

Low

1121330

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.249

Low

1121331

CYTM1
Cysteine-rich and transmembrane domain-containing protein 1

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024