Protein: FAD1
FAD synthase (EC 2.7.7.2) (FAD pyrophosphorylase) (FMN adenylyltransferase) (Flavin adenine dinucleotide synthase) [Includes: Molybdenum cofactor biosynthesis protein-like region; FAD synthase region]

Gene: FAD1, FLAD1
Organism: Homo sapiens
Interactions: 110
UniProt ID: Q8NFF5

Gene Ontology (top 5):
GO:0003919 - FMN adenylyltransferase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1338788

FAD1
FAD synthase

5

3

High-throughput

0.927

High

783341

TRI23
E3 ubiquitin-protein ligase TRIM23

4

0

High-throughput

0.663

High

1338813

PRDC1
Phosphoribosyltransferase domain-containing protein 1

4

0

High-throughput

0.663

High

1048922

REL
Proto-oncogene c-Rel

3

0

High-throughput

0.646

High

1338815

KLH14
Kelch-like protein 14

3

0

High-throughput

0.638

High

140371

SDCB1
Syntenin-1

2

0

High-throughput

0.601

High

882784

EFTU
Elongation factor Tu, mitochondrial

1

0

High-throughput

0.586

High

1338800

EFGM
Elongation factor G, mitochondrial

1

0

High-throughput

0.586

High

711726

RABP2
Cellular retinoic acid-binding protein 2

2

0

High-throughput

0.580

High

896829

DYN2
Dynamin-2

2

0

High-throughput

0.580

High

1338806

NIF3L
NIF3-like protein 1

2

0

High-throughput

0.580

High

1338817

CSN3
COP9 signalosome complex subunit 3

2

0

High-throughput

0.580

High

467698

CEL2A
Chymotrypsin-like elastase family member 2A

2

0

High-throughput

0.576

High

808121

CDN1A
Cyclin-dependent kinase inhibitor 1

2

0

High-throughput

0.570

High

1211385

CLVS2
Clavesin-2

2

1

High-throughput

0.553

High

1275327

APTX
Aprataxin

2

1

High-throughput

0.553

High

1338799

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.536

High

1338801

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.536

High

900044

FXR1
RNA-binding protein FXR1

1

0

High-throughput

0.518

High

987419

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

0

High-throughput

0.513

High

1123354

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.513

High

1310245

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1338789

BICD2
Protein bicaudal D homolog 2

1

0

High-throughput

0.513

High

1338803

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

1

0

High-throughput

0.513

High

405513

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.486

High

627996

ANXA7
Annexin A7

1

0

High-throughput

0.486

High

1126625

GRB7
Growth factor receptor-bound protein 7

1

0

High-throughput

0.486

High

1160519

SMN
Survival motor neuron protein

1

0

High-throughput

0.486

High

242335

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

532786

CH60
60 kDa heat shock protein, mitochondrial

1

4

High-throughput

0.479

High

942759

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

1

High-throughput

0.479

High

1090470

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

2

High-throughput

0.479

High

1091826

TP4A2
Protein tyrosine phosphatase type IVA 2

1

2

High-throughput

0.479

High

1207078

SYAM
Alanine--tRNA ligase, mitochondrial

1

1

High-throughput

0.479

High

1338802

DUS9
Dual specificity protein phosphatase 9

1

1

High-throughput

0.479

High

1338804

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

1

High-throughput

0.479

High

944522

GEMI4
Gem-associated protein 4

1

0

High-throughput

0.460

High

61559

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.458

High

279427

TULP3
Tubby-related protein 3

1

0

High-throughput

0.458

High

279837

CISY
Citrate synthase, mitochondrial

1

0

High-throughput

0.458

High

294051

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

315792

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

350928

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.458

High

471143

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.458

High

519167

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

611238

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.458

High

719353

MPIP3
M-phase inducer phosphatase 3

1

0

High-throughput

0.458

High

828858

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

831093

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

851959

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

872550

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

970804

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1015613

RHOG
Rho-related GTP-binding protein RhoG

1

0

High-throughput

0.458

High

1058151

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1083674

MPPA
Mitochondrial-processing peptidase subunit alpha

1

0

High-throughput

0.458

High

1106621

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.458

High

1113748

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1117785

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.458

High

1142604

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

1162433

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.458

High

1224867

TENS2
Tensin-2

1

0

High-throughput

0.458

High

1234457

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

1334666

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1335502

MTMRE
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR14

1

0

High-throughput

0.458

High

1338792

RBCC1
RB1-inducible coiled-coil protein 1

1

0

High-throughput

0.458

High

1338794

FAKD4
FAST kinase domain-containing protein 4

1

0

High-throughput

0.458

High

1338795

MCUR1
Mitochondrial calcium uniporter regulator 1

1

0

High-throughput

0.458

High

1338797

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.458

High

1338805

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.458

High

1338807

IF3M
Translation initiation factor IF-3, mitochondrial

1

0

High-throughput

0.458

High

1338808

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1338809

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

1338810

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

1338814

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

1338818

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

0

High-throughput

0.458

High

326746

DUS14
Dual specificity protein phosphatase 14

1

1

High-throughput

0.437

High

1338793

TP4A1
Protein tyrosine phosphatase type IVA 1

1

3

High-throughput

0.437

High

638216

S1PR1
Sphingosine 1-phosphate receptor 1

1

0

High-throughput

0.426

High

653451

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

854553

S15A1
Solute carrier family 15 member 1

1

0

High-throughput

0.426

High

1209411

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1338819

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

0

High-throughput

0.426

High

1338791

PKHO2
Pleckstrin homology domain-containing family O member 2

3

0

High-throughput

0.347

High

1279010

TAFA3
Chemokine-like protein TAFA-3

2

0

High-throughput

0.328

High

1338811

FSCN3
Fascin-3

2

0

High-throughput

0.328

High

1213511

UBAP2
Ubiquitin-associated protein 2

2

0

High-throughput

0.318

High

1338798

LMBL3
Lethal(3)malignant brain tumor-like protein 3

2

0

High-throughput

0.316

High

587145

ITF2
Transcription factor 4

1

0

High-throughput

0.299

High

505103

BNIP5
Protein BNIP5

1

0

High-throughput

0.279

Low

938537

CCL18
C-C motif chemokine 18

1

0

High-throughput

0.279

Low

1200314

ANR39
Ankyrin repeat domain-containing protein 39

1

0

High-throughput

0.279

Low

1208226

SPXN4
Sperm protein associated with the nucleus on the X chromosome N4

1

0

High-throughput

0.279

Low

1241191

DUS1L
tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like

1

0

High-throughput

0.279

Low

1338790

SG1C1
Secretoglobin family 1C member 1

1

0

High-throughput

0.279

Low

1338796

ZN689
Zinc finger protein 689

1

0

High-throughput

0.279

Low

1338812

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.279

Low

1338816

FOXD3
Forkhead box protein D3

1

0

High-throughput

0.279

Low

1119626

CNCG
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma

1

0

High-throughput

0.269

Low

1220546

OTP
Homeobox protein orthopedia

1

0

High-throughput

0.269

Low

228323

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.265

Low

616344

RCC1
Regulator of chromosome condensation

1

0

High-throughput

0.265

Low

176077

KDM6B
Lysine-specific demethylase 6B

1

0

Small-scale

0.249

Low

341628

EYA4
Protein phosphatase EYA4

1

0

High-throughput

0.249

Low

543431

PSG1
Pregnancy-specific beta-1-glycoprotein 1

1

0

High-throughput

0.249

Low

768685

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1135741

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.249

Low

1254719

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1290250

MGDP1
Magnesium-dependent phosphatase 1

1

0

High-throughput

0.249

Low

1332278

GG6L2
Golgin subfamily A member 6-like protein 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025