Protein: WBP11
WW domain-binding protein 11 (WBP-11) (Npw38-binding protein) (NpwBP) (SH3 domain-binding protein SNP70) (Splicing factor that interacts with PQBP-1 and PP1)

Gene: WBP11
Organism: Homo sapiens
Interactions: 140
UniProt ID: Q9Y2W2

Gene Ontology (top 5):
GO:0003697 - single-stranded DNA binding
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

968048

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

7

6

Small-scale

0.751

High

786947

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

7

6

Small-scale

0.745

High

257285

PQBP1
Polyglutamine-binding protein 1

7

0

Small-scale

0.719

High

1390197

MCRS1
Microspherule protein 1

3

2

High-throughput

0.671

High

1055293

MTG8
Protein CBFA2T1

3

3

High-throughput

0.667

High

286511

WBP4
WW domain-binding protein 4

3

4

Small-scale

0.665

High

1369428

DDX17
Probable ATP-dependent RNA helicase DDX17

3

2

High-throughput

0.660

High

988053

GRB2
Growth factor receptor-bound protein 2

2

20

High-throughput

0.633

High

1154201

ITSN1
Intersectin-1

2

8

High-throughput

0.620

High

335940

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

2

1

Small-scale

0.620

High

766034

BMI1
Polycomb complex protein BMI-1

2

8

High-throughput

0.611

High

943833

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

2

11

High-throughput

0.606

High

1148967

SC23A
Protein transport protein Sec23A

2

8

High-throughput

0.606

High

260635

BRD4
Bromodomain-containing protein 4

2

4

High-throughput

0.584

High

373556

MYC
Myc proto-oncogene protein

2

11

High-throughput

0.584

High

1067862

EP300
Histone acetyltransferase p300

2

9

High-throughput

0.584

High

440798

FYN
Tyrosine-protein kinase Fyn

1

9

High-throughput

0.573

High

1309685

ARHGJ
Rho guanine nucleotide exchange factor 19

2

3

High-throughput

0.571

High

1369952

ARHG1
Rho guanine nucleotide exchange factor 1

2

4

High-throughput

0.571

High

1336588

MORN4
MORN repeat-containing protein 4

2

3

High-throughput

0.553

High

1385055

CHP3
Calcineurin B homologous protein 3

1

0

High-throughput

0.549

High

1414808

TRAF4
TNF receptor-associated factor 4

1

0

High-throughput

0.549

High

1490967

3BP1
SH3 domain-binding protein 1

2

0

High-throughput

0.547

High

222230

NCK2
Cytoplasmic protein NCK2

1

20

High-throughput

0.541

High

938147

ANM2
Protein arginine N-methyltransferase 2

1

2

High-throughput

0.541

High

1014984

ARF1
ADP-ribosylation factor 1

1

3

High-throughput

0.541

High

1150899

CIP4
Cdc42-interacting protein 4

1

3

High-throughput

0.541

High

1361854

RSPH1
Radial spoke head 1 homolog

1

3

High-throughput

0.541

High

173590

XPO1
Exportin-1

1

8

High-throughput

0.536

High

316642

ST17B
Serine/threonine-protein kinase 17B

1

2

High-throughput

0.536

High

612334

ARF4
ADP-ribosylation factor 4

1

3

High-throughput

0.536

High

634703

LMNB1
Lamin-B1

1

5

High-throughput

0.536

High

968494

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

6

High-throughput

0.536

High

1368813

EZH1
Histone-lysine N-methyltransferase EZH1

1

13

High-throughput

0.536

High

1413575

H2AJ
Histone H2A.J

1

7

High-throughput

0.536

High

1490970

MB212
Protein mab-21-like 2

1

1

High-throughput

0.536

High

158678

TYB4Y
Thymosin beta-4, Y-chromosomal

1

0

High-throughput

0.513

High

686692

3BHS2
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2

1

0

High-throughput

0.513

High

879766

MAPK2
MAP kinase-activated protein kinase 2

1

0

High-throughput

0.513

High

948615

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.513

High

1036561

ID2
DNA-binding protein inhibitor ID-2

1

0

High-throughput

0.513

High

1117719

NOG2
Nucleolar GTP-binding protein 2

1

0

High-throughput

0.513

High

1142825

PEA15
Astrocytic phosphoprotein PEA-15

1

0

High-throughput

0.513

High

1148887

PP1R7
Protein phosphatase 1 regulatory subunit 7

1

0

High-throughput

0.513

High

1404929

PARK7
Parkinson disease protein 7

1

0

High-throughput

0.513

High

1411880

TCAL7
Transcription elongation factor A protein-like 7

1

0

High-throughput

0.513

High

608797

DDX5
Probable ATP-dependent RNA helicase DDX5

1

2

High-throughput

0.508

High

914004

RBM5
RNA-binding protein 5

1

5

High-throughput

0.508

High

1438569

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

1

1

Small-scale

0.508

High

1146882

PCBP1
Poly(rC)-binding protein 1

1

2

High-throughput

0.506

High

1458750

MO4L1
Mortality factor 4-like protein 1

1

0

High-throughput

0.493

High

694419

CO8A1
Collagen alpha-1(VIII) chain

1

3

High-throughput

0.489

High

1178519

KI26B
Kinesin-like protein KIF26B

1

1

High-throughput

0.489

High

1395093

JPH4
Junctophilin-4

1

4

High-throughput

0.489

High

1461600

ANR50
Ankyrin repeat domain-containing protein 50

1

3

High-throughput

0.489

High

1361547

CTBL1
Beta-catenin-like protein 1

1

0

High-throughput

0.486

High

944909

PCBP4
Poly(rC)-binding protein 4

1

2

High-throughput

0.481

High

127212

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

High-throughput

0.480

High

191168

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

3

High-throughput

0.479

High

272565

OBSL1
Obscurin-like protein 1

1

10

High-throughput

0.479

High

285533

EED
Polycomb protein EED

1

6

High-throughput

0.479

High

298467

DNJC8
DnaJ homolog subfamily C member 8

1

5

High-throughput

0.479

High

302676

RNF8
E3 ubiquitin-protein ligase RNF8

1

2

Small-scale

0.479

High

401733

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

7

High-throughput

0.479

High

406820

MYCN
N-myc proto-oncogene protein

1

12

High-throughput

0.479

High

522023

H14
Histone H1.4

1

6

High-throughput

0.479

High

590083

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.479

High

607245

CEBPB
CCAAT/enhancer-binding protein beta

1

6

High-throughput

0.479

High

696920

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

714537

PML
Protein PML

1

5

High-throughput

0.479

High

769568

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.479

High

905315

MECP2
Methyl-CpG-binding protein 2

1

2

High-throughput

0.479

High

946917

H2B1D
Histone H2B type 1-D

1

20

High-throughput

0.479

High

985080

RL31
Large ribosomal subunit protein eL31

1

1

High-throughput

0.479

High

995911

ACTC
Actin, alpha cardiac muscle 1

1

2

High-throughput

0.479

High

998979

H31
Histone H3.1

1

10

High-throughput

0.479

High

1024948

VIGLN
Vigilin

1

3

High-throughput

0.479

High

1033322

EWS
RNA-binding protein EWS

1

4

High-throughput

0.479

High

1127266

RBM39
RNA-binding protein 39

1

8

High-throughput

0.479

High

1128158

DHX8
ATP-dependent RNA helicase DHX8

1

1

High-throughput

0.479

High

1133063

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

3

High-throughput

0.479

High

1138785

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

3

High-throughput

0.479

High

1148676

SF3A2
Splicing factor 3A subunit 2

1

7

High-throughput

0.479

High

1152683

ELAV1
ELAV-like protein 1

1

3

High-throughput

0.479

High

1155930

EZH2
Histone-lysine N-methyltransferase EZH2

1

13

High-throughput

0.479

High

1235578

IFIX
Pyrin and HIN domain-containing protein 1

1

1

High-throughput

0.479

High

1238515

ZN746
Zinc finger protein 746

1

1

High-throughput

0.479

High

1258989

H32
Histone H3.2

1

10

High-throughput

0.479

High

1277001

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

6

High-throughput

0.479

High

1290840

ZCH18
Zinc finger CCCH domain-containing protein 18

1

5

High-throughput

0.479

High

1313554

SMC5
Structural maintenance of chromosomes protein 5

1

2

High-throughput

0.479

High

1351205

SP7
Transcription factor Sp7

1

4

High-throughput

0.479

High

1367644

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1369883

CELF1
CUGBP Elav-like family member 1

1

4

High-throughput

0.479

High

1387653

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

5

High-throughput

0.479

High

1408071

H2B1L
Histone H2B type 1-L

1

20

High-throughput

0.479

High

1414625

DDX23
Probable ATP-dependent RNA helicase DDX23

1

3

High-throughput

0.479

High

1428431

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

10

High-throughput

0.479

High

1438096

RC3H2
Roquin-2

1

8

High-throughput

0.479

High

1448793

RNC
Ribonuclease 3

1

2

High-throughput

0.479

High

1452487

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

1

High-throughput

0.479

High

1458772

NXF1
Nuclear RNA export factor 1

1

1

High-throughput

0.479

High

1459387

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

1490966

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

1

High-throughput

0.479

High

1490969

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

1

High-throughput

0.479

High

134919

SAP18
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.458

High

248155

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

476206

ANXA5
Annexin A5

1

0

High-throughput

0.458

High

906467

DHB4
Peroxisomal multifunctional enzyme type 2

1

0

High-throughput

0.458

High

1241860

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

1446354

NGB
Neuroglobin

1

0

High-throughput

0.458

High

1461314

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.458

High

1490968

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

1251474

GGYF2
GRB10-interacting GYF protein 2

1

9

Small-scale

0.457

High

430540

JUN
Transcription factor Jun

1

10

High-throughput

0.445

High

530629

TAU
Microtubule-associated protein tau

1

11

High-throughput

0.445

High

1064050

ECHP
Peroxisomal bifunctional enzyme

1

1

High-throughput

0.445

High

412852

NTRK1
High affinity nerve growth factor receptor

1

12

High-throughput

0.437

High

1256187

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.437

High

1452297

TBA8
Tubulin alpha-8 chain

1

1

High-throughput

0.437

High

1454780

HECW2
E3 ubiquitin-protein ligase HECW2

1

7

High-throughput

0.437

High

915036

AK1C2
Aldo-keto reductase family 1 member C2

1

0

High-throughput

0.426

High

1420029

UBL5
Ubiquitin-like protein 5

1

0

Small-scale

0.426

High

1453784

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

0

High-throughput

0.426

High

887359

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

High-throughput

0.408

High

1034545

TAGL
Transgelin

1

1

High-throughput

0.407

High

1180760

LETM2
LETM1 domain-containing protein LETM2, mitochondrial

1

1

High-throughput

0.407

High

1193592

CE022
UPF0489 protein C5orf22

5

0

High-throughput

0.377

High

1359819

RT4I1
NAD(P)H oxidoreductase RTN4IP1, mitochondrial

1

0

High-throughput

0.282

High

276196

NIPS2
Protein NipSnap homolog 2

1

0

High-throughput

0.279

Low

292784

RENR
Renin receptor

1

0

High-throughput

0.279

Low

488090

IFI6
Interferon alpha-inducible protein 6

1

0

High-throughput

0.279

Low

1093787

GAGE5
G antigen 5

1

0

High-throughput

0.279

Low

1218131

CP141
Cilia- and flagella-associated protein 141

1

0

High-throughput

0.279

Low

1384738

I27L1
Interferon alpha-inducible protein 27-like protein 1

1

0

High-throughput

0.279

Low

1392198

RUSF1
RUS family member 1

1

0

High-throughput

0.279

Low

1452961

PEN2
Gamma-secretase subunit PEN-2

1

0

High-throughput

0.279

Low

1490971

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.279

Low

1273889

T2R42
Taste receptor type 2 member 42

1

0

High-throughput

0.232

Low

1436768

GHC1
Mitochondrial glutamate carrier 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025