Protein: NUP42
Nucleoporin NUP42 (NLP-1) (NUP42 homolog) (Nucleoporin hCG1) (Nucleoporin-42) (Nucleoporin-like protein 2)

Gene: NUP42
Organism: Homo sapiens
Interactions: 148
UniProt ID: O15504

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005049 - nuclear export signal receptor activity
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

192594

GLE1
mRNA export factor GLE1

4

1

Small-scale

0.687

High

192610

CARME
Carnosine N-methyltransferase

4

0

High-throughput

0.661

High

192640

MKRN2
E3 ubiquitin-protein ligase makorin-2

3

1

High-throughput

0.656

High

192639

NXF2
Nuclear RNA export factor 2

2

1

High-throughput

0.628

High

192586

PUM1
Pumilio homolog 1

2

1

High-throughput

0.611

High

192645

MOV10
Helicase MOV-10

2

2

High-throughput

0.611

High

192667

IF2B2
Insulin-like growth factor 2 mRNA-binding protein 2

2

2

High-throughput

0.611

High

192576

RAE1L
mRNA export factor RAE1

2

0

High-throughput

0.585

High

192534

KRT34
Keratin, type I cuticular Ha4

2

0

High-throughput

0.580

High

192615

NUP35
Nucleoporin NUP35

2

0

High-throughput

0.559

High

192608

ARHGJ
Rho guanine nucleotide exchange factor 19

2

0

High-throughput

0.547

High

192525

AQR
RNA helicase aquarius

1

2

High-throughput

0.536

High

192530

SRS10
Serine/arginine-rich splicing factor 10

1

2

High-throughput

0.536

High

192531

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

1

High-throughput

0.536

High

192539

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

2

High-throughput

0.536

High

192541

SNRPA
U1 small nuclear ribonucleoprotein A

1

2

High-throughput

0.536

High

192543

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

2

High-throughput

0.536

High

192546

H12
Histone H1.2

1

1

High-throughput

0.536

High

192547

NUCL
Nucleolin

1

1

High-throughput

0.536

High

192549

H1T
Histone H1t

1

1

High-throughput

0.536

High

192562

CLK2
Dual specificity protein kinase CLK2

1

1

High-throughput

0.536

High

192563

CLK3
Dual specificity protein kinase CLK3

1

1

High-throughput

0.536

High

192564

NU153
Nuclear pore complex protein Nup153

1

1

High-throughput

0.536

High

192574

RAN
GTP-binding nuclear protein Ran

1

1

High-throughput

0.536

High

192582

SRSF1
Serine/arginine-rich splicing factor 1

1

1

High-throughput

0.536

High

192584

ELAV2
ELAV-like protein 2

1

1

High-throughput

0.536

High

192589

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

2

High-throughput

0.536

High

192595

LAR1B
La-related protein 1B

1

1

High-throughput

0.536

High

192597

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

1

High-throughput

0.536

High

192600

LARP1
La-related protein 1

1

1

High-throughput

0.536

High

192606

RBM45
RNA-binding protein 45

1

3

High-throughput

0.536

High

192616

PUM2
Pumilio homolog 2

1

1

High-throughput

0.536

High

192617

SRS12
Serine/arginine-rich splicing factor 12

1

2

High-throughput

0.536

High

192619

CELF1
CUGBP Elav-like family member 1

1

2

High-throughput

0.536

High

192620

RENT1
Regulator of nonsense transcripts 1

1

2

High-throughput

0.536

High

192623

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

1

High-throughput

0.536

High

192633

ATX2
Ataxin-2

1

1

High-throughput

0.536

High

192638

CRNL1
Crooked neck-like protein 1

1

1

High-throughput

0.536

High

192646

SYF1
Pre-mRNA-splicing factor SYF1

1

1

High-throughput

0.536

High

192650

STAU2
Double-stranded RNA-binding protein Staufen homolog 2

1

1

High-throughput

0.536

High

192657

MKRN1
E3 ubiquitin-protein ligase makorin-1

1

1

High-throughput

0.536

High

192660

RALY
RNA-binding protein Raly

1

1

High-throughput

0.536

High

192551

APC
Adenomatous polyposis coli protein

1

0

High-throughput

0.518

High

192628

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.518

High

63909

CNOT1
CCR4-NOT transcription complex subunit 1

1

0

High-throughput

0.513

High

183401

CASC3
Protein CASC3

1

0

High-throughput

0.513

High

192526

PRP17
Pre-mRNA-processing factor 17

1

0

High-throughput

0.513

High

192527

XYLK
Glycosaminoglycan xylosylkinase

1

0

High-throughput

0.513

High

192528

PTCD1
Pentatricopeptide repeat-containing protein 1, mitochondrial

1

0

High-throughput

0.513

High

192529

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

0

High-throughput

0.513

High

192532

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

0

High-throughput

0.513

High

192536

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.513

High

192538

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.513

High

192545

H2AX
Histone H2AX

1

0

High-throughput

0.513

High

192552

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.513

High

192554

NKTR
NK-tumor recognition protein

1

0

High-throughput

0.513

High

192561

RANG
Ran-specific GTPase-activating protein

1

0

High-throughput

0.513

High

192569

NU107
Nuclear pore complex protein Nup107

1

0

High-throughput

0.513

High

192573

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.513

High

192575

YBOX1
Y-box-binding protein 1

1

0

High-throughput

0.513

High

192577

RT05
Small ribosomal subunit protein uS5m

1

0

High-throughput

0.513

High

192578

RT09
Small ribosomal subunit protein uS9m

1

0

High-throughput

0.513

High

192583

NCBP1
Nuclear cap-binding protein subunit 1

1

0

High-throughput

0.513

High

192585

FADD
FAS-associated death domain protein

1

0

High-throughput

0.513

High

192587

IMB1
Importin subunit beta-1

1

0

High-throughput

0.513

High

192588

NUMA1
Nuclear mitotic apparatus protein 1

1

0

High-throughput

0.513

High

192590

SF3A1
Splicing factor 3A subunit 1

1

0

High-throughput

0.513

High

192591

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.513

High

192593

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.513

High

192599

ZC3HE
Zinc finger CCCH domain-containing protein 14

1

0

High-throughput

0.513

High

192601

F111B
Serine protease FAM111B

1

0

High-throughput

0.513

High

192602

MARK2
Serine/threonine-protein kinase MARK2

1

0

High-throughput

0.513

High

192604

PABP2
Polyadenylate-binding protein 2

1

0

High-throughput

0.513

High

192607

ABC3F
DNA dC->dU-editing enzyme APOBEC-3F

1

0

High-throughput

0.513

High

192613

PPHLN
Periphilin-1

1

0

High-throughput

0.513

High

192618

B2CL2
Bcl-2-like protein 2

1

0

High-throughput

0.513

High

192621

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.513

High

192624

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.513

High

192625

TRI11
E3 ubiquitin-protein ligase TRIM11

1

0

High-throughput

0.513

High

192629

ZFR
Zinc finger RNA-binding protein

1

0

High-throughput

0.513

High

192630

YTDC1
YTH domain-containing protein 1

1

0

High-throughput

0.513

High

192631

UIF
UAP56-interacting factor

1

0

High-throughput

0.513

High

192635

NUP58
Nucleoporin p58/p45

1

0

High-throughput

0.513

High

192636

RM13
Large ribosomal subunit protein uL13m

1

0

High-throughput

0.513

High

192637

RM01
Large ribosomal subunit protein uL1m

1

0

High-throughput

0.513

High

192643

DHX36
ATP-dependent DNA/RNA helicase DHX36

1

0

High-throughput

0.513

High

192647

NGRN
Neugrin

1

0

High-throughput

0.513

High

192649

ZCHC3
Zinc finger CCHC domain-containing protein 3

1

0

High-throughput

0.513

High

192652

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

1

0

High-throughput

0.513

High

192653

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

0

High-throughput

0.513

High

192655

RM15
Large ribosomal subunit protein uL15m

1

0

High-throughput

0.513

High

192659

NXT1
NTF2-related export protein 1

1

0

High-throughput

0.513

High

192661

ISY1
Pre-mRNA-splicing factor ISY1 homolog

1

0

High-throughput

0.513

High

192665

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

192666

CCDC9
Coiled-coil domain-containing protein 9

1

0

High-throughput

0.513

High

192540

RHOC
Rho-related GTP-binding protein RhoC

1

2

High-throughput

0.479

High

192544

RAC2
Ras-related C3 botulinum toxin substrate 2

1

2

High-throughput

0.479

High

192566

RAB7A
Ras-related protein Rab-7a

1

1

High-throughput

0.479

High

192567

RAB9A
Ras-related protein Rab-9A

1

1

High-throughput

0.479

High

192572

RHOA
Transforming protein RhoA

1

2

High-throughput

0.479

High

192592

CPEB4
Cytoplasmic polyadenylation element-binding protein 4

1

1

High-throughput

0.479

High

192627

FUBP3
Far upstream element-binding protein 3

1

2

High-throughput

0.479

High

192654

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

2

High-throughput

0.479

High

192656

NXF1
Nuclear RNA export factor 1

1

1

High-throughput

0.479

High

192556

NU214
Nuclear pore complex protein Nup214

1

0

Small-scale

0.460

High

156709

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

192524

CTIF
CBP80/20-dependent translation initiation factor

1

0

High-throughput

0.458

High

192533

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.458

High

192535

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

192537

MYCN
N-myc proto-oncogene protein

1

0

High-throughput

0.458

High

192548

RAB5A
Ras-related protein Rab-5A

1

0

High-throughput

0.458

High

192553

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

192555

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

192557

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

192558

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

192565

EMD
Emerin

1

0

High-throughput

0.458

High

192570

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.458

High

192571

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

192579

H33
Histone H3.3

1

0

High-throughput

0.458

High

192596

RNF43
E3 ubiquitin-protein ligase RNF43

1

0

High-throughput

0.458

High

192603

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

192605

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

0

High-throughput

0.458

High

192611

DHB11
Estradiol 17-beta-dehydrogenase 11

1

0

High-throughput

0.458

High

192612

LS14A
Protein LSM14 homolog A

1

0

High-throughput

0.458

High

192614

NUP43
Nucleoporin Nup43

1

0

High-throughput

0.458

High

192644

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

192651

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.458

High

192663

DD19B
ATP-dependent RNA helicase DDX19B

1

0

High-throughput

0.458

High

192664

RL26L
Ribosomal protein uL24-like

1

0

High-throughput

0.458

High

192542

PAB4L
Polyadenylate-binding protein 4-like

1

1

High-throughput

0.445

High

192559

HELZ
Probable helicase with zinc finger domain

1

2

High-throughput

0.445

High

192568

SEC13
Protein SEC13 homolog

1

0

Small-scale

0.438

High

192550

RAE1
Rab proteins geranylgeranyltransferase component A 1

1

0

High-throughput

0.426

High

192641

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

0

High-throughput

0.426

High

75888

B4DEF8
Large ribosomal subunit protein mL45

1

0

High-throughput

0.279

Low

192658

IL17B
Interleukin-17B

1

0

High-throughput

0.279

Low

192560

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.249

Low

192580

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.249

Low

192598

FBX42
F-box only protein 42

1

0

High-throughput

0.249

Low

192609

CXD3
Gap junction delta-3 protein

1

0

High-throughput

0.249

Low

192622

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.249

Low

192626

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

192632

SEC62
Translocation protein SEC62

1

0

High-throughput

0.249

Low

192634

DERL1
Derlin-1

1

0

High-throughput

0.249

Low

192642

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.249

Low

192648

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.249

Low

192662

ALK
ALK tyrosine kinase receptor

1

0

High-throughput

0.249

Low

192581

TAP1
Antigen peptide transporter 1

1

0

Small-scale

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025